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PubMed2003

[Specific features of tuberculin sensitivity in children with allergic dermatoses].

The recent rise in the incidence of allergic diseases, including allergic dermatoses, requires a comprehensive approach to solving a number of problems associated with this disease. Analyzing the case reports of 62 children with allergic dermatoses has indicated that this is a particular contingent of children, which needs a more careful approach to different preventive measures, to interpreting tuberculin reactions and hence to substantiating the use chemotherapeutical prevention. A graded skin tuberculin test and an immunological study should be performed in critical cases.

Child↗
PubMed2003

[Phototherapy and photochemotherapy of inflammatory dermatoses].

Stubborn and extensive dermatoses, such as psoriasis vulgaris or atopic dermatitis (eczema), are indications for phototherapeutic methods. These include UVB phototherapy, UVA photochemotherapy (PUVA), UVA irradiation following prior photosensitization, UVA, treatment and combination treatments. Phototherapy is contraindicated in the case of light-induced dermatoses. Caution must also be exercised in patients receiving photosensitizing medications. When establishing the indication, consideration must be given to the treatment-related increased risk of developing skin cancer. The patient must also be informed of such undesired potential side effects as burns and premature aging of the skin.

Administration, Topical↗
PubMed2003

A continuous spectrum of neutrophilic dermatoses in Crohn's disease.

UNLABELLED: The inflammatory bowel disease is accompanied by cutaneous manifestations in approximately 10% of the cases. Neutrophilic dermatoses are located on the dermis and/or epidermis and are characterised on histological examination by the presence of an infiltrate that consists largely of neutrophils. The prototype of neutrophilic dematoses is Sweetacute;s syndrome; which is rarely associated with Crohńs disease. CASE REPORT: A 63 year old woman was admitted to hospital with pyrexia, abdominal pain, episcleritis and skin lesions. She presented erythematous lesions on trunk, legs and arms, with tendency towards formation of plaques, nodules and vesicular pustular lesions. Both the colonoscopy and colonic biopsies confirmed the diagnosis of colonic Crohńs disease. Cutaneous biopsies re-vealed an infiltrate consisting mainly of neutrophils. These biopsies, together with clinical details led to the diagnosis of Sweetacute;s syndrome. A methylprednisolone treatment rapidly improved the skin lesions and clinical symptoms. The different clinical forms of neutrophilic dermatosis are an extra intestinal manifestation of Crohńs disease, and are some-times found concurrently in the same patient, which would indicate a common pathogenesis with different clinical presentations (spectrum of neutrophilic dermatoses).

Crohn Disease↗
PubMedDate not supplied

Vitamin A acid in acneiform dermatoses.

A definition and classification of acneiform dermatoses is presented to distinguish these diseases from true acne. True acne is a follicular eruption which begins with a comedo, sometimes evolving into various inflammatory lesions. Members of true acne are acne vulgaris with its varieties, acne venenata, and comedonal acne due to physical agencies. Acneiform reactions begin with an inflammatory lesion, usually a papule or pustule. Comedones are uncommon and may follow pustules. Acneiform eruptions are almost always drug-induced, the commonest agents being corticosteroids and ACTH, iodides, bromides, anti-convulsive drugs, and INH. Topical treatment with VAA is indicated in every variety of true acne; VAA is helpful in acneiform dermatoses with secondary comedo formation, as for instance in steroid acne. Very satisfying results can be achieve with this regimen.

Acne Vulgaris↗
PubMed2003

[Life quality in patients with sarcoidosis and isolated skin syndrome in chronic dermatoses].

Seventeen patients, including 3 (17.6%) males and 14 (82.4%) females, who had respiratory sarcoidosis with the skin syndrome as erythema nodosum, were examined; their mean age was 41.65 +/- 2.63 years. The histological verification of the diagnosis was 94%. Among 77 patients with chronic dermatoses with the isolated skin syndrome (psoriasis, acne vulgaris, atopic dermatitis, neurodermitis, lichen ruber planus, seborrheal pemphigns, eczema), there were 33 (42.9%) males and 44 (57.1%) females, whose mean age was 36.64 +/- 1.3 years. Comparative analysis of life quality (LQ) in these two groups by using the WHOQOL-100 questionnaire revealed differences in two indices that reflect the level of independence and social relations (p < or = 0.05). In terms of independence, the impact of the disease on LQ was more pronounced in patients with sarcoidosis, its negative effect being in 75% of the criteria rated. Thus, poorer LQ may be stated in patients with skin lesion than in those with the isolated skin syndrome in chronic dermatoses.

Adult↗
PubMed1977

[Occupational dermatoses reported in the Lódź district in the years 1972-1976].

108 cases were evaluated. It was stated that they were mostly caused by an exposure to allergic effects of industrial allergens: metal compounds, epoxides, paragroup compounds, turpentine, formalin and rubber components. Location and clinical picture of dermatoses constitute mainly dermatitis and contact eczema on the skin of hands. The cases referred mainly to the men employed in building, chemical, textile and metal industries. Opening a center performing allergic tests with industrial allergents, which at the same time could determine their occurrence in work environment, provides the basic condition for a proper diagnosis and prophylaxis of occupational dermatoses.

Adult↗
PubMed2004

Prevalence of self-reported hand dermatoses in New Zealand dentists.

OBJECTIVES: To estimate the self-reported prevalence of hand dermatoses and irritation to the eyes, nose and airway among New Zealand dentists. MATERIALS AND METHODS: A cross-sectional survey used a postal questionnaire sent to all practising dentists on the New Zealand Dental Register. RESULTS: The response rate was 81.3 percent. Over 40 percent of dentists had experienced symptoms at some stage during their practising life, and one-third reported experience of symptoms during the previous 12 months. Prevalence was higher among females, more recent graduates, and those suffering from hay fever, asthma or any other allergic condition. One-third of sufferers had consulted a medical practitioner about the problem. Multivariate modelling showed that females had twice the odds of experiencing symptoms at some time during their practising life (after controlling for time since graduation, allergies and hay fever, lifelong wearing of gloves, and hobbies involving exposure to solvents). Those who reported hobbies involving solvents were over 11 times as likely to report having experienced symptoms at some time during their practising life. CONCLUSIONS: A substantial proportion of the dental practice workforce in New Zealand is at risk for occupational dermatoses. Reducing exposure to potential allergens and irritants is the key to minimising that risk.

Adult↗
PubMed1978

[Dermatoses in tapestry workers].

From among 810 persons subjected to a medical examination, skin lesions were found in 33.3%. These were mostly: seborrhea (89 cases), occupational naevi (55 cases), dermatomycosis (49 cases), urticaria (21 cases), eczema (12 cases). Other dermatoses were found in 44 workers, however, in a small percentage, not greater than in other non-industrial populations. No occupational dermatoses resulting from exposure to fundamental materials or dyes used in production were found.

Adolescent↗
PubMed1994

Occupational dermatoses among workers in a porcelain manufacturing factory.

The objectives of the present work are to determine the prevalence and risk factors of occurrence of occupational dermatoses among workers in a porcelain manufacturing factory. The study included 235 workers (132 males and 103 females). After history taking, dermatological examination was performed at the work place. Cases of contact dermatitis (CD) were patch tested using potassium dichromate 0.5%, Cobalt chloride 1% and Nickel sulphate 5% in petrolatum. Results showed that the prevalence of occupational dermatoses (OD) was 26.8% among exposed workers. The highest percentage of OD was found among workers in the decoration department. It represented 30.2% of all cases. CD was the commonest presentation among the studied group, it represented 27% of all cases of OD. Results of patch testing indicated that out of 17 cases of CD 12 cases (70%) were of the irritant variety and 5 cases (30%) were of the allergic type. The prevalence of OD was found to be affected by age, duration of work, type of exposure and daily bathing after work.

Adolescent↗
PubMed1989

[Measures for the combined therapy and prevention of dermatoses occurring in workers in contact with organophosphorus pesticides].

Allergenic and photosensitizing effects of organophosphorus pesticides (OPP) have been detected, as well as their destructive effect on the skin cell ultrastructure, on the body metabolism and enzymic systems, and the inhibitory effect on cholinesterase activity. Pesticide-induced changes in polyunsaturated fatty acids (PUFA) are significant in the mechanism of dermatoses development. The complex of treatment-and-prophylaxis measures includes regular dermatologic check-ups and limitation of the number of subjects handling OPP. Subjects in whom premorbid shifts have been detected, should be followed up. The therapy and prevention of the dermatoses developing as a result of exposure to pesticides may be effectively carried out with antioxidants, amino acids, vitamins, etc.; diets with the optimal PUFA-tocopherol ratio are advisable. Overalls with multiple protective physicochemical characteristics, filtering respirators and such are recommended.

Agricultural Workers' Diseases↗
PubMedDate not supplied

[Phencarol in the treatment of allergic dermatoses of various pathological mechanisms].

Phencarol produced in the USSR is an antihistaminic drug highly effective in allergic dermatoses with the pathological mechanism of humoral and cellular type. The best results were obtained in acute allergic dermatoses and in acute recurrences of chronic allergic diseases. In comparative studies with difergan a greater efficiency of phencarol was noted, which was expressed as a higher proportion regression of lesions and more rapid action of the drug. The duration of phencarol treatment was about 3 weeks, the daily dose was 50-75 mg in adults. The drug was well tolerated.

Adolescent↗
PubMed1989

[Secondary candidal infection in patients with chronic dermatoses].

Clinical and laboratory examinations of 250 patients with chronic dermatoses (eczema, neurodermatitis, psoriasis, pemphigus, etc.) have revealed secondary candidal involvement of the skin and mucosa in 121 (46.6%). C. albicans, often associated with bacillary (33.3%) or bacterial (7.3%) microflora, predominated among the yeast-like fungi isolated from the patients. These data point to the necessity of prescribing, besides the antimycotic agents, a complex of pathogenetic therapy including immunomodulators, in order to cut down the terms of treatment and prevent secondary candidal infection in the patients with chronic dermatoses.

Adolescent↗
PubMed1989

[Eczema diseases and erythemato-squamous dermatoses of aging skin--studies of the effectiveness and tolerance of Prednicarbate in various vehicles].

In an open multi-center study on 1,286 patients aged 60 years and more, we tested the efficacy and compatibility of prednicarbate (Dermatop) in various vehicles. The eczemas and erythematosquamous dermatoses of 857 patients (66.6%) disappeared within three weeks treatment. In 142 patients (11%), it took more than 3 weeks (62 day at the most) to achieve a complete healing. A very good or good tolerance was observed in 97.1% of the patients. Only in 1.5% the study had to be broken off because of a change for the worse. Prednicarbate, therefore, is especially suitable in the treatment of eczemas and chronic erythematosquamous dermatoses of aged skin.

Aged↗
PubMed1989

[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].

The blood plasma levels of a number of endogenous prostaglandins have been measured by column chromatography followed by radioimmunoassay in 33 patients with psoriasis and in 22 children with allergic dermatoses. The findings evidence an increase of these prostanoids at the peak of the skin process exacerbation, thus indicating their role in the pathogenesis of psoriasis and allergic dermatoses in children.

6-Ketoprostaglandin F1 alpha↗
PubMed1989

[Morbidity from allergic dermatoses and pruritus in Blagoveshchensk].

The intensive morbidity index in respect of allergic dermatoses has made up 12.07 in 1986, allergic dermatitis being the most prevalent (72%). The morbidity has been the highest among subjects aged 21 to 40. Seasonal changes in the allergic dermatoses incidence rates have been determined: skin itching, urticaria, and neurodermatitis have been the most prevalent in October, whereas eczema occurred mostly in May.

Age Factors↗
PubMed1985

[Protective skin ointments. Their value in preventing occupational dermatoses].

The application of topical skin protectant products is discussed. Their primary indication is prophylaxis of non-allergic contact dermatitis. In persons already sensitized a reliable prevention of allergic contact eczema is doubtful. The methods which have been used in the past to prove the efficacy of skin protective ointments are examined critically. Most of the model experiments are of an acute character. They do not adequately suit the practical work situation, where occupational dermatoses develop after frequent contact with relatively small doses of noxious substances. A repetitive patch-test method is presented and with the use of two skin protective agents it is demonstrated how the efficacy of such products can be proven. For effective preventive measures in industry, it is recommended that skin protection plans be set up. It has been proven that such measures reduce the morbidity rate of occupational dermatoses, which serves to show its economical importance.

Animals↗
PubMed1988

[Structural-functional characteristics of the surface of the blood mononucleocytes in children suffering from chronic dermatoses. I. The correction of the glycocalyx structure by UV irradiation of the blood and in the course of treatment with an autotransfusion of UV-irradiated blood].

In children suffering from chronic dermatoses (psoriasis and neurodermatitis), the glycocalix of blood mononuclears displays an Alcian blue dye sorption by 23-25% less than that in healthy children. The UV irradiation of their blood (254 nm), in addition to a course of UV-irradiated blood autotransfusion, resulted in an elevated sorption capacity of the mononuclear glycocalix up to the normal. A possible involvement of these changes in immunocompetent cell glycocalix in the pathogenesis of chronic dermatoses is discussed, as well as the significance of glycocalix normalization in the medicinal effect of UV-irradiated blood autotransfusion.

Absorption↗