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PubMedDate not supplied

Aneurysmal bone cyst of the larynx.

Aneurysmal bone cyst is a rare lesion of the head and neck, and the mandible and maxilla are the most common sites of occurrence. To the authors' knowledge, two cases of aneurysmal bone cyst of the larynx described here are the first to be reported. Although the exact pathogenesis of this lesion is unknown, several theories of its origin are discussed. Complete surgical excision is the treatment of choice. Radiation therapy for this benign lesion is not indicated because of a possible association with the development of sarcoma. Histologic misdiagnosis of carcinoma or sarcoma of the larynx leading to unnecessary radical surgery is a risk and should be avoided by obtaining expert pathologic consultation.

Adult↗
PubMed2004

Aneurysmal bone cyst of the maxilla.

An aneurysmal bone cyst of the maxilla is a nonneoplastic, uncommon, solitary bone lesion recognized by distinct radiographic and histopathological characteristics. It is described as a localized and quickly expandable benign tumor, which can reach a considerable size. It is characterized by the replacement of bone by spongy fibro-osseous tissue and a locally destructive and multicystic lesion filled with blood. It is attributed to a circulatory disturbance leading to locally increased venous pressure but with an unclear etiology. It takes place mainly in the long bones and in patients less than 20 years old, with no sex predilection. Its treatment is by surgical excision. An aneurysmal bone cyst in the facial bone is rare. The present case describes the lesion arising in the maxilla of a 14-year-old girl.

Adolescent↗
PubMed2004

Autologous bone marrow injection in the management of simple bone cysts in children.

The majority of simple bone cysts (SBC's) is not symptomatic and remains undiagnosed or is discovered fortuitously. A number of simple bone cysts are only diagnosed after a pathological fracture which occurs as a presenting symptom. Fractures are managed either conservatively or surgically, based on criteria such as the age of the child and the type and localisation of the fracture. The risk for fracture can be evaluated radiographically. In the absence of a fracture risk, plain radiographic follow-up is sufficient. In case of a high fracture risk, percutaneous aspiration and injection of bone marrow may be performed. The result of this treatment in 21 simple bone cysts with a high risk for fracture is reported. Slow regression of the cyst and progressive healing were obtained in 15 cases (71.4%) whereas no response was noted in 3 cases (14.3%) and recurrence in another 3 (14.3%), after a mean follow-up of 37.1 months. Guidelines are proposed for the follow-up and management of SBC.

Adolescent↗
PubMed1982

Aneurysmal bone cyst and other nonneoplastic conditions.

Aneurysmal bone cyst is a benign proliferative tumefaction of bone. Histologic similarities indicate a kinship among classic aneurysmal bone cysts, essentially "solid" proliferative lesions in bones; giant cell reparative granulomas of the jaws, at the base of the skull, and in the small bones of the hands and feet; skeletal lesions of hyperparathyroidism; and even pseudosarcomatous myositis ossificans, proliferative myositis, and proliferative fasciitis.

Adolescent↗
PubMed2004

Soft tissue aneurysmal bone cyst.

A soft tissue aneurysmal bone cyst located in the right gluteus medius of a 21-year-old man is reported. On conventional radiography, the lesion demonstrated a spherically trabeculated mass with a calcific rim. On CT scan, it showed a well-organized peripheral calcification resembling a myositis ossificans. On MRI, it presented as a multilocular, cystic lesion with fluid-fluid levels. The lesion had no solid components except for intralesional septa. Although findings on imaging and histology were identical to those described in classical aneurysmal bone cyst, diagnosis was delayed because of lack of knowledge of this entity and its resemblance to the more familiar post-traumatic heterotopic ossification (myositis ossificans).

Adult↗
PubMed1987

Aneurysmal bone cyst associated with a dentigerous cyst: report of case.

An aneurysmal bone cyst associated with a dentigerous cyst filled the entire maxillary right sinus and corresponding eroding portions. The report discusses the unusual presence of a dentigerous cyst, documentation of an aneurysmal bone cyst associated with a primary lesion, and offers suggestions as to the common pathogenesis of the two lesions.

Adult↗
PubMed1985

Aneurysmal bone cyst: a hybrid lesion?

A case of aneurysmal bone cyst in the maxilla is reported which developed following the excision of a cementifying fibroma from the same site. Aneurysmal bone cyst has been seen previously in association with other osseous lesions in the jaws and in other bones. A review of the literature revealed 58 cases of aneurysmal bone cyst in the jaws, of which 13 were associated with other bone disease. One theory of pathogenesis of aneurysmal bone cyst is supported by the finding of such hybrid lesions.

Adolescent↗
PubMed1999

Aneurysmal bone cysts of the spine.

Thirteen patients with aneurysmal bone cyst of the spine (excluding sacral lesions) were retrospectively reviewed. Treatment for aneurysmal bone cysts remains controversial, but surgical resection, irradiation, and embolization are common treatment modalities for those involving the spine. Of 102 patients with aneurysmal bone cysts, 15 had a lesion of the spine, including 2 sacral cases. Of the 13 patients with a lesion of the thoracic or lumbar spine, 9 underwent resection of the lesion, 2 curettage and cementation, and 2 only currettage. Eleven patients underwent segmental arthrodesis with instrumentation after treatment of the primary or recurrent lesion, while 2 patients underwent segmental arthrodesis using autogeneic bone. Nine patients did not develop a local recurrence after resection of the lesion. However, the 2 patients who underwent curettage alone developed local recurrences. None of 4 patients developed recurrences after curettage and cementation. After recurrence, 1 patient underwent additional resection with irradiation, and 1 patient underwent resection alone. At the final follow-up, all lesions were under control. In one patient, lumbar kyphosis developed after segmental arthrodesis with instrumentation, and arthrodesis was performed again. Radical resection of aneurysmal bone cysts of the spine with instrumentation is the optimal method of acquiring a high degree of local control and preventing spinal deformity.

Adolescent↗
PubMed1995

Calcifying solitary bone cyst: morphological aspects and differential diagnosis of sclerotic bone tumours.

Fourteen solitary bone cysts (SBC) with large areas of calcification (7 in the femur, 4 in the humerus, and 1 each in the pelvis, the tibia and the scapula) and 402 SBC from the Hamburg Bone Tumour Registry were reviewed in a retrospective study. The analysis was done with emphasis on the clinical, radiological and histological appearances. SBC are well known lesions, but calcifying SBC (CSBC) or extensive extragnathic cement-like bone productions are rare. The clinical and radiological differential diagnosis includes fibrous dysplasia, chondroma, low-grade chondrosarcoma and osteosarcoma. Bits of this cement-like matrix are detectable within the wall of approximately 70% (278 of 402) of SBC from the registry. CSBC are changed SBC. The intraoperative confirmation of the diagnosis on a frozen section by the bone pathologist leads to curettage which is currently the most common therapy in this benign lesion.

Adolescent↗
PubMed1984

[Fractures in benign bone cysts].

Etiology, clinical manifestations, roentgenographic appearance and histological variations of solitary and aneurysmatic bone cyst are reported. The classification of solitary bone cyst into active and inactive cysts is important therefore prognosis and treatment are different. The critical control of our patients with fractured solitary and aneurysmatic bone cysts since 1973 resulted in a very contenting management of treatment. Active solitary bone cysts, recurrent cysts, fractured cysts and large cysts close to joints are treated by segmental resection, interposing of ribs, homologous or autogenous cancellous bone graft and plate osteosynthesis. We never found recidives under this treatment. The only curettage of active solitary bone cyst frequently is accompanied by recidive and unsatisfying functional results. Reports of local corticoid injections in treatment of bone cysts should be furthermore controlled critical.

Adolescent↗
PubMed2002

[Finite element analysis of the development of subchondral bone cysts].

In principle three different types of subchondral bone cysts have been described in literature: subchondral bone cysts in osteoarthritis, subchondral bone cysts in rheumatoid arthritis and in intraosseous ganglia. However, an exact differentiation of these lesion types has not yet been defined, as there is no consensus on etiology. The aim of this study is the investigation of the etiology of cysts using finite element analysis. We assume that local cartilage lesions, i.e. the typical arthritic joint disease, can cause cysts. The results of these investigations are confirmed by clinical observations. Cartilage lesions generating stress induced microfractures may be able to explain the process of subchondral cyst formation. We assume that bone resorption is caused primarily by local overload. Moreover, local stress concentration along the border of cysts may account for their tendency to enlarge.

Arthritis, Rheumatoid↗
PubMed2004

Cytogenetic and molecular cytogenetic findings in 43 aneurysmal bone cysts: aberrations of 17p mapped to 17p13.2 by fluorescence in situ hybridization.

Aneurysmal bone cyst is a benign, cystic lesion of bone composed of blood-filled spaces separated by fibrous septa. Relatively few cases of aneurysmal bone cyst have been cytogenetically characterized, yet abnormalities of the short arm of chromosome 17 appear to be recurrent. In this study, conventional cytogenetic analysis of 43 aneurysmal bone cyst specimens from 38 patients over a 12-year period revealed clonal chromosomal abnormalities in 12 specimens. Karyotypic anomalies of 17p, including a complex translocation and inversion, were identified in eight of these 12 specimens. In an effort to further define the aberrant 17p breakpoint, fluorescence in situ hybridization (FISH) analyses were performed using a series of probe combinations spanning a 5.1 Mb region between the TP53 (17p13.1) and Miller-Dieker lissencephaly syndrome (17p13.3) gene loci. These studies revealed the critical breakpoint locus at 17p13.2, flanked proximally by an RP11-46I8, RP11-333E1, and RP11-457I18 bacterial artificial chromosome (BAC) probe cocktail and distally by an RP11-198F11 and RP11-115H24 BAC and RP5-1050D4 P1 artificial chromosome (PAC) probe cocktail. Overall, abnormalities of the 17p13.2 locus were identified by metaphase and/or interphase cell FISH analysis in 22 of 35 (63%) aneurysmal bone cyst specimens examined including 26 karyotypically normal specimens. These cytogenetic and molecular cytogenetic findings expand our knowledge of chromosomal alterations in aneurysmal bone cyst, further localize the critically involved 17p breakpoint, and provide an alternative approach (ie FISH) for detecting 17p abnormalities in nondividing cells of aneurysmal bone cysts. The latter could potentially be utilized as an adjunct in diagnostically challenging cases.

Adult↗
PubMed2003

Bone cysts in sarcoidosis: what is their clinical significance?

The incidence of bone cysts in sarcoidosis, a multisystemic disease, varies in different series, and these cysts are generally asymptomatic. We evaluated bone cysts in 516 sarcoidosis patients with available hand X-rays and in 200 patients with foot X-rays. Bone cysts were present in 21 cases (19 females, two males). The cysts were localized in phalanges of the hand in all cases, in feet in five cases, and in nasal bone in one. Six patients with bone cysts also had lupus pernio. Among those with cystic bone lesions, females were more frequent; extrapulmonary and skin involvement and lupus pernio were significantly more common. We diagnosed cystic bone lesions in 3.6% of our sarcoidosis patients and conclude that cysts were more frequent in females and in patients with lupus pernio.

Adult↗
PubMed1993

Packing with high-porosity hydroxyapatite cubes alone for the treatment of simple bone cyst.

In 23 patients, simple bone cysts were treated by curettage followed by packing the cavity with cubes of high-porosity hydroxyapatite (HA). In 22 patients, HA was packed exclusively without autogeneic bone graft. Except in one patient who sustained pathologic fracture at the femoral diaphysis, HA was packed with a fibula strut graft. Each case had an uneventful postoperative course and was followed, on average, two years. Complete healing without cyst recurrence occurred in 18 cases (78%). In three cases--all rapidly growing children--a new cyst appeared between the epiphyseal plate and the HA packing, but the original cysts did not recur. In two multiloculated cysts, the cavities were not filled fully and healing was incomplete, yet there was no cyst recurrence. In the entire group, new bone surrounding HA was roentgenographically evident within an average of 2.3 months. Thus, the result of packing high-porosity HA for simple bone cysts compares favorably with the cure rates reported either with autogeneic bone graft, or topical steroid injection.

Adolescent↗
PubMed2006

Primary aneurysmal bone cyst of coronoid process.

BACKGROUND: Aneurysmal bone cysts are relatively uncommon in the facial skeleton. These usually affect the mandible but origin from the coronoid process is even rarer. To the best of our knowledge, this is the first reported case of a coronoid process aneurysmal bone cyst presenting as temporal fossa swelling. CASE PRESENTATION: A 17 year old boy presented with a progressively increasing swelling in the left temporal region developed over the previous 8 months. An expansile lytic cystic lesion originating from the coronoid process of the left mandible and extending into the infratemporal and temporal fossa regions was found on CT scan. It was removed by a superior approach to the infratemporal fossa. CONCLUSION: Aneurysmal bone cyst of the coronoid process can attain enormous dimensions until the temporal region is also involved. A superior approach to the infratemporal fossa is a reasonable approach for such cases, providing wide exposure and access to all parts of the lesion and ensuring better control and complete excision.

Journal Article↗
PubMed1982

Juxta-articular bone cyst.

Juxta-articular bone cyst was first described as a distinct clinical entity by Hicks in 1956 and called "intraosseous ganglion". Hitherto, some 150 similar cases have been described. The cyst, which is usually solitary, occurs in the epiphysis near a weight-bearing joint in middle-aged persons. It may cause persistent pain but is easily overlooked on ordinary X-rays. The histogenesis is uncertain. Six patients treated by thorough curettage and autologous bone transplantation are presented. All achieved immediate relief from pain. Some theoretical aspects concerning the histogenesis are discussed.

Adult↗
PubMed1979

Two atypical solitary bone cysts.

Two atypical solitary bone cysts occurring posterior to the angle of the mandible, and in each case showing delayed healing, are reported. Some speculations are made on the possible aetiology of these lesions in general.

Adolescent↗