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[Combination therapy of porphyria cutanea tarda using chloroquine and bloodletting therapy].

14 patients with PCT were treated with phlebotomy combined with Chloroquine. 4 venesections were performed before Chloroquine-treatment administered intermittently twice weekly. The so-called flu-syndrome manifested itself in the majority of patients. The clinical symptoms of PCT regressed within 6 weeks to 4 months of treatment, and the urinary uroporphyrin excretion returned to normal within 6 weeks to 3 months. Besides the flu-syndrome no side-effects could be observed. There has been a clinical and biochemical remission for a year and a half in each case but one. Relapse occurred in one case only one year after treatment.

Adult↗

[Comparative evaluation of the protective effect of furantril and bloodletting in experimental pulmonary edema].

The author carried out studies on the protective effect of furanthril and bleeding, administered 15 minutes before adrenaline in rabbits with lung oedema induced by adrenaline. The gravity of lung oedema was evaluated by the size of lung coefficient and percentage of the survivals. The obtained results showed that furanthril in a dose of 15 mg per kg showed considerably more manifested effect in comparison with that of bleeding of 7 ml per kg. Their combined usage revealed stronger protective action in comparison with their single application.

Acute Disease↗

Bloodletting.

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Bloodletting↗

[Erroneous diagnosis of lithium poisoning due to use of lithium-heparin bloodletting tubes].

In two male patients, aged 53 and 21 years, lithium intoxication was suspected. The diagnosis was apparently confirmed by blood testing (the lithium concentrations amounted to 3.68 and 1.82 mmol/l, respectively). Retrospectively however it was found that blood sampling tubes with lithium-heparin as the anticoagulant had been used. No lithium intoxication was present in the patients. Clear instructions in writing are necessary to prevent this error.

Adult↗