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At least 217 records · Page 12Linked to original sources

Bicuspid aortic valve in an adult human cadaver: a case report.

We encountered a "bicuspid" aortic valve in an 83-year-old man. This valve consisted of two semilunar leaflets, anterior and posterior, though they were extensively calcified. The right and left coronary arteries independently arose from the anterior aortic sinus. The infundibular ligament ran from the pulmonary trunk at the commissure of the right and left semilunar cusps to the aorta at the mid-point of the anterior sinus. These findings strongly suggests the present bicuspid aortic valve may be formed by fusion of usual right and left (coronary) cusps. No other congenital anomalies were noted in this heart.

Aged↗

[Rare association of a bicuspid aortic valve and accessory azygous lobe in Turner syndrome. Echocardiographic and clinical findings].

The frequency of cardiovascular anomalies in patients affected by Turner's syndrome is well recognized. Its most frequent anomalies are aortic coarctation and a bicuspid aortic valve which are both found in 30% of cases. Other frequent anomalies are the dilatation of the ascending aorta, the aortic valve stenosis and/or insufficiency, the partial anomalous pulmonary venous drainage, and the interatrial septal defect. The aortic dissection and the aortic aneurysmal rupture, both complications of the cystic media necrosis of the aorta, are unusual, but dramatic, in their manifestations. The authors illustrate the case of a 6 year old female with Turner's syndrome by chance come under their observation for a cardiological evaluation according to which an azigos lobe and a bicuspid aortic valve. The authors consider it is the first time that an investigator has pointed out the association of these anomalies in Turner's syndrome. The authors believe that the illustrated case confirms the value of an echocardiographic evaluation as regards patients with Turner's syndrome, even with no findings of cardiovascular disease.

Aortic Valve↗

[Valvuloplasty for aortic insufficiency in a patient with bicuspid aortic valve].

A 20-year-old man with a bicuspid valve underwent aortic valvuloplasty for aortic regurgitation. Valvuloplasty was performed according to Cosgrove's method. Intraoperative transesophageal color Doppler echocardiography showed trivial aortic regurgitation after the repair. Peak pressure gradient across the repaired aortic valve was 9.3 mmHg at rest (cardiac output 4.2 l/min, stroke volume 49 ml) and 27.6 mmHg at dobutamine infusion (cardiac output 8.7 l/min, stroke volume 78 ml). The patient was in NYHA class I with no medication after surgery. Valvuloplasty for aortic regurgitation with a bicuspid valve is the surgical procedure of choice.

Adult↗

The bicuspid nature of the valves of the peripheral collecting lymphatic vessels of the dog.

A controversy presently exists about the structure of lymphatic valves, the bicuspid structure vs. the funnel-like architechture. This present study, along with a review of the literature was undertaken in an attempt to clarify this controversy. Twenty lymphatic valves from the collecting lymphatic channels draining the back paw region in four dogs were examined and several were photographed. The bicuspid nature and the three dimensional anatomy of these valves is clearly demonstrated.

Animals↗

Endodontic therapy in a mandibular second bicuspid with four canals.

Success in endodontic therapy often depends on the removal of the critical concentration of pulp tissue or necrotic debris within the root canal system. The best method to ensure this objective is to locate and instrument all of the canals in the root of the tooth. Therefore, a thorough knowledge of root canal morphology is essential to reduce the chances of failure. The purpose of this article is to report a case of mandibular second bicuspid with four distinct canals.

Bicuspid↗

Results of surgical exposure of impacted cuspids and bicuspids in relation to patients' somatic and dental maturation.

The aim of the study was to correlate the rate of postoperative eruption of impacted teeth after surgical exposure to the patient?S' SOMATIC AND DENTAL DEVELOPMENT. THIS RELATIONSHIP WAS ANALYZED IN 31 PATIENTW WITH IMPACTED CUSPIDS OR BICUSPIDS, 12 OF WHOM WERE OVER 25 AND 19 UNDER 21 YEARS OF AGE. Surgical uncovering of the impacted teeth was carried out and the degree of subsequent eruption was evaluated 4 months after the operation. On uncovering the crown was exposed as far as the cementoenamel juction and the surrounding bone was covered with mucous membrane. Dental age and growth rate were used as variables describing individual somatic and dental maturation. After surgical uncovering eruption took place in all but one tooth. Eruption was quicker and more complete in children who were still growing than in young adults. The eruption process was also more favorable in dentitions still under formation than in cases with completed dental development. Early intervention and total surgical uncovering of the crown are advocated in cases of impacted teeth.

Adolescent↗

Supernumerary impactions of the mandibular cuspids and bicuspids. Case report.

A case involving the presence of supernumerary cuspids and bicuspids is described. The condition was probably an inherited one because of the family history and the bilateral incidence. The supernumerary teeth erupted because of alveolar resorption in which inflammatory factors probably played a role. Radiographic follow-up of the site of supernumerary impacted teeth and alveolar resorption should be undertaken.

Aged↗

[Resistance to fracture of direct restorations with cuspal coverage in endodontically treated upper bicuspids].

Endodontically treated teeth are considered more susceptible to fracture because of the loss of tooth structure. The aim of this study was to evaluate the increase of resistance to fracture of upper bicuspids that underwent endodontic access and were restored with composite resin, with cuspal coverage. Forty extracted human maxillary premolars were divided in 4 groups: I--intact teeth; II--teeth with endodontic access and MOD preparation, restored with composite resin, without cuspal coverage; III--teeth with endodontic access, MOD preparation and occlusal reduction, restored with composite resin, with cuspal coverage; IV--teeth with endodontic access and MOD preparation, without any restoration. The test specimens were submitted to compression test up to their fracture. The test of Turkey and the ANOVA analysis were used to compare and test the results. The teeth from group III (with cuspal coverage) presented with significantly greater resistance to fracture, when compared with those from groups II (restored without cuspal coverage) and IV (not restored). The composite restoration with cuspal coverage can be considered an alternative for endodontically treated premolars.

Bicuspid↗

Effects of combined topical metronidazole and mechanical treatment on the subgingival flora in deep periodontal pockets in cuspids and bicuspids.

The Effect on the subgingival microflora of a single topical administration of a 95% collagen and 5% metronidazole device in combination with debridement was investigated in 30 adult periodontitis patients in comparison with mechanical treatment alone. For each patient, plaque samples from test and control sites in cuspids and bicuspids were collected for culture and enumeration of total anaerobically cultivable bacteria (TA), black-pigmented anaerobes (BPA), and Actinobacillus actinomycetemcomitans (Aa). Spirochetes and fusiforms were quantified by direct microscopic examination after Giemsa staining. A decrease was observed for all parameters, and a significant difference in comparison with the control group was found for fusiforms. After treatment, a lower number of Aa positive sites were observed in the test group (13/25). These results show that a single application of topical metronidazole seems to be effective as adjunctive antimicrobial treatment in adult periodontitis.

Administration, Oral↗

Caveat preparator: maxillary second bicuspid root invaginations.

Seventy-five percent of maxillary second bicuspids have a single pulpal canal. The remainder present dual canals with one or two associated apical orifices and proximal root concavities. This latter phenomenon may well lead to root perforations when placing posts. The following case documents such an occurrence.

Bicuspid↗

The clinical management of congenitally absent and malformed maxillary lateral incisors and second bicuspids.

A number of options have been presented to treat patients with congenitally absent (or malformed) MLI's and second bicuspids. Overall the treatment of choice was shown to be essentially dependent on diagnostic parameters, length of treatment time, facial esthetics and age of patient. Orthodontic space closure is the treatment of choice since it should result in a lasting natural healthy dentition. In prosthetic cases, implant-supported or otherwise, the skill of the practitioner and the quality of the prosthesis, plus the general health and the oral hygiene of the patient, would be important considerations to ensure longevity of the prostheses. TMJ dysfunction occurring during orthodontic treatment is a possibility. Procedures that may precipitate a dormant predisposition to these kind of difficulties should be carefully evaluated and/or compensated.

Anodontia↗

Familial congenital bicuspid aortic valve: a disorder of uncertain inheritance.

Congenital bicuspid aortic valve (BAV) is one of the most frequent heart defects detected by echocardiographic investigation and necropsy (0.9-1% of the general population), but only 16 families with familial congenital BAV have been described up to now. We report on a family in which 4 members of two generations (2 brothers, 1 sister, and her son) are affected with BAV. The BAV mode of inheritance is discussed.

Adult↗

Familial patent ductus arteriosus and bicuspid aortic valve with hand anomalies: a novel heart-hand syndrome.

The association between cardiac and limb defects, particularly those affecting the hand, has been well documented by the delineation of several heart-hand syndromes. Based on observations with a three-generation family with seven affected individuals, we describe a novel heart-hand syndrome comprising patent ductus arteriosus, bicuspid aortic valve, 5th metacarpal hypoplasia, and brachydactyly. The inheritance pattern was consistent with autosomal dominance, although X-linked dominance could not be excluded. Penetrance appeared to be complete, but there was variability of the cardiac and hand phenotypes. Because this new syndrome closely resembled Char syndrome (patent ductus arteriosus, 5th finger middle phalangeal hypoplasia, and minor facial anomalies), multipoint linkage analysis was performed using polymorphic DNA markers spanning the recently identified Char syndrome critical region at chromosomal bands 6p12-p21.1. This analysis formally excluded this 3-cM region, documenting that the two traits are not allelic. In sum, a novel heart-hand syndrome involving left ventricular outflow and aortic arch as well as an ulnar ray derivative has been identified. Because the hand anomalies can be subtle, thorough evaluation is suggested for families inheriting these cardiac defects as a mendelian trait.

Alleles↗

Ascending aortic aneurysm and dissection in young adults with bicuspid aortic valve: implications for echocardiographic surveillance.

Bicuspid aortic valve (BAV) is an independent risk factor for aneurysm and dissection of the ascending aorta. Despite this association, routine imaging of the aorta has not been recommended for patients with BAV. We describe two young men who developed life-threatening aneurysm or dissection of the ascending aorta; one had a normally functioning BAV and the other was 10 years after valve replacement. The pathology of this condition is very similar to that found in the Marfan syndrome. We recommend echocardiographic surveillance of the ascending aorta at regular intervals, and consideration of beta-adrenergic blockade among patients with significant dilation.

Adult↗

Direction, site of origin and duration of jets: implications in the color Doppler assessment of valvar lesions. With emphasis on pure and combined mitral and bicuspid aortic lesions.

Color Doppler imaging has renewed and widened the capabilities of the flow mapping technique. In addition to its facilitation, it has some specific advantages: by showing the spatio-temporal variations of jets within the cardiac cycle, it provides a quadri-dimensional insight into flow dynamics, which has improved the semi-quantitative assessment of the severity in mitral regurgitation by taking into account the duration of the regurgitant jet within systole. It is also crucial for the study of multiple jets often seen in combined mitral disease and related to various diseased components of the mitral apparatus. Peculiar features of sites, directions and timings of jets enable the recognition of their mechanisms and draw the attention to a possible surface adherence effect, in the case of complicated trajectories impinging on the cardiac structures. Color Doppler imaging is also unique in singling out the precise site where the jets originate. This leads to developments of quantitation of stenosis based on planimetry of jet origin areas and to new quantitative methods relying on flow convergence information on one hand, and on the other hand, it helps approach to special lesional mechanisms such as, for instance bicuspid aortic valves, easily singled out by flow information from tricuspid aortic valves. This information will be crucial in the discussion of the type of repair procedure in the future.

Aortic Valve Insufficiency↗

A case of hypoplastic left heart syndrome and bicuspid aortic valve in monochorionic twins.

The etiology of hypoplastic left heart syndrome (HLHS) remains unclear. Since a genetic cause for HLHS has not been obvious, it is generally considered to be inherited in a multifactorial manner. Studies of twins are valuable in elucidating the genetic contribution to a birth defect such as HLHS. We report a case of monochorionic twins in whom one has HLHS and the other has a bicuspid aortic valve. Predisposing genetic and environmental influences on individuals with identical genotypes, such as twins, may result in discordance of left-sided flow lesions.

Aortic Valve↗

[Noonan's syndrome with an unusual combination of hypertrophic cardiomyopathy, congenital bicuspid aortic valve, coarctation of the aorta and hypoplastic aortic arch].

Noonan's syndrome is characterized by craniofacial anomalies, i. e. ptosis, webbing of the neck and a deep nuchal hairline, as well as skeletal deformities such as short stature, clinodactyly, pectus carinatum and funnel chest and other organ anomalies, mainly cardiac valve disease, less often testicular retention or kidney malformations. Noonan syndrome presents with aspects similar to Ullrich-Turner syndrome, but can be found in both male and female patients. In about one half of the patients with Noonan's syndrome cardiovascular anomalies occur, mostly anomalies of the right heart (mainly valvular pulmonary stenosis). Aortic stenosis and coarctation of the aorta are rarely seen. We report on a patient with four sequential potentially stenosing and stenosed parts of the proximal systemic circulation: hypertrophic cardiomyopathy, bicuspid aortic valve, coarctation of the aorta and a hypoplastic aortic arch as a part of Noonan's syndrome. This patient presents with a unique combination of anomalies, as he also shows a Madelung like deformity of the wrist.

Adult↗