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Indirect MR arthrography: concepts and controversies.

Indirect MR arthrography involves intravenous injection of a standard dose of Gadolinium contrast followed, in delayed fashion, by MR imaging. Contrast in taken up by the joint at a rate dependent on a variety of factors including synovial area, vascularity, permeability, and pre-existing joint effusion. Patient acceptance is higher than with direct intra-articular injection, and logical considerations (e.g., not needing a radiologist present) make this an attractive alternative to direct MR arthrography. At best, an indirect MR arthrography exam can look virtually identical to a direct MR arthrogram. However, the radiologist should be aware that vascular tissue inside and outside the joint will enhance, which may be considered either an advantage or disadvantage. Additionally, since all compartments of the joint enhance, information regarding abnormal communication of contrast material is absent. Suboptimal exams occur due to the need for diffusion of contrast into the joint. Exercise can help improve the quality of exams. Using an adequate time delay is essential for optimizing indirect MR arthrography.

Contrast Media↗

Labral-ligamentous complex of the shoulder. Evaluation with double oblique axial MR arthrography.

PURPOSE: To assess the ability of double oblique axial (DOA) MR arthrography in evaluating labral-ligamentous complex compared with conventional axial (CA) MR arthrography. MATERIAL AND METHODS: MR arthrography of 51 shoulders, subsequently examined with arthroscopy, were retrospectively reviewed. DOA imaging was performed in all 51 shoulders and both DOA and CA imaging in 37 using a 1.5 T unit with gradient recalled-echo T2*-weighted sequences. DOA imaging was performed using perpendicular planes to the long axis of the glenoid fossa obtained by an oblique sagittal scout image. We compared the ability of DOA with that of CA MR arthrography to assess labral injuries and to demonstrate the whole length of the anterior band of the inferior glenohumeral ligament (AIGHL), which were shown to be intact by arthroscopy. RESULTS: For anterior labral injuries, sensitivity and specificity were 87% and 93% with CA, and 94% and 100% with DOA imaging, respectively. For posterior labral injuries, sensitivity and specificity were 47% and 100% with CA, and 79% and 96% with DOA imaging, respectively. There were no statistically significant differences between CA and DOA images, except for the ability to diagnose posterior labral injuries, where DOA imaging had a significant superior sensitivity (p=0.0327). DOA images also demonstrated the whole length of the intact AIGHL in 10 of 11 shoulders, while CA imaging showed this in only 3 of 11. CONCLUSION: DOA imaging was equal or better than CA imaging for evaluating the labral-ligamentous complex.

Adult↗

Arthrographis keratitis mimicking acanthamoeba keratitis.

OBJECTIVE: To describe a case of keratomycosis caused by Arthrographis kalrae, mimicking Acanthamoeba keratitis. METHODS: Case report. RESULTS: A 23-year-old female contact lens wearer developed dendritic keratitis in her amblyopic eye (OD). Baseline vision was 20/50. Treatment with trifluridine 1% resulted in resolution of the dendrite, but an area of stromal haze developed, spreading to a discontinuous ring shape, and the vision dropped to 20/200. Photophobia was intense, and pain was out of proportion to the examination. Cultures were sent, and empiric treatment of Acanthamoeba was begun, without subsequent improvement. After 4 weeks, cultures were positive for a fungal species. Amphotericin 0.5% drops were begun, with moderately rapid resolution of the active keratitis. At last follow-up, best-corrected vision was 20/100. Review of the culture showed the organism to be Arthrographis kalrae. CONCLUSION: Arthrographis kalrae has been reported only once before as an ocular pathogen. As in the previously reported case of Arthrographis, our patient's presentation was strongly suggestive of Acanthamoeba keratitis.

Acanthamoeba Keratitis↗

Ligamentous and tendinous anatomy of the intermetacarpal and common carpometacarpal joints: evaluation with MR imaging and MR arthrography.

PURPOSE: The purpose of this work was to demonstrate the normal ligamentous and tendinous anatomy of the intermetacarpal (IMC) and common carpometacarpal (CCMC) joints with MRI and MR arthrography. METHOD: MR images of 22 wrists derived from fresh human cadavers were obtained before and after arthrography. The MR imaging features of the ligaments and tendons about the CCMC and IMC joints and the joints themselves were analyzed in a randomized fashion and correlated with those seen on anatomic sections. RESULTS: Six CCMC ligaments were visualized. The dorsal and palmar CCMC ligaments and the pisometacarpal ligament were best visualized in the sagittal plane. The radial and ulnar CCMC collateral ligaments and the capito-third metacarpal ligament were best visualized in the coronal plane. Three main IMC ligaments were observed: a dorsal and a palmar ligament and an interosseous ligament complex. All three ligaments were best visualized in the axial plane. Four tendinous insertions to the metacarpal bases were evident. CONCLUSION: The anatomy of the ligaments and tendinous insertions about the second to fifth IMC and the CCMC joints is well demonstrated by MR imaging and MR arthrography. MR arthrography does not significantly improve the visualization of these complex structures.

Aged↗

Evaluation of popliteal cysts and painful calves with ultrasonography: comparison with arthrography.

Grey-scale ultrasonography will detect reliably the presence of clinically significant popliteal cysts, fluid collections which do not fill by arthrography, and will frequently demonstrate ruptured cysts and the soft tissue changes resulting from a recent leak. Forty-eight knees, in 25 patients with popliteal and/or calf pain were examined by ultrasonography followed by arthrography. Popliteal cysts were demonstrated in 40% (19/48) by ultrasound and in 46% (22/48) by arthrogram. For comparison between arthrography and ultrasonography chi2 = 8.58 and contingency coefficient, phi = 0.42 (p less than 0.01). Acute cyst rupture was shown in 2 patients (8%) by both arthrography and ultrasound. In a further study ultrasonography demonstrated popliteal cysts with a prevalence of 31% (22/72) in 36 patients with definite or classical rheumatoid arthritis compared with 4% (3/72) in controls closely matched for age and sex. This difference in prevalence between the rheumatoid patients and controls was highly significant chi2 = 17.48, p less than 0.001. Ultrasonography, therefore, will demonstrate noninvasively the presence of popliteal cysts, may assist in the diagnosis of rupture, and furthermore will assist in quantitative, sequential assessment of patients with painful knees and calves.

Aged↗

CT arthrography of the glenohumeral joint: CT fluoroscopy versus conventional CT and fluoroscopy--comparison of image-guidance techniques.

PURPOSE: To compare examination time with radiologist time and to measure radiation dose of computed tomographic (CT) fluoroscopy, conventional CT, and conventional fluoroscopy as guiding modalities for shoulder CT arthrography. MATERIALS AND METHODS: Glenohumeral injection of contrast material for CT arthrography was performed in 64 consecutive patients (mean age, 32 years; age range, 16-74 years) and was guided with CT fluoroscopy (n = 28), conventional CT (n = 14), or conventional fluoroscopy (n = 22). Room times (arthrography, room change, CT, and total examination times) and radiologist times (time the radiologist spent in the fluoroscopy or CT room) were measured. One-way analysis of variance and Bonferroni-Dunn posthoc tests were performed for comparison of mean times. Mean effective radiation dose was calculated for each method with examination data, phantom measurements, and standard software. RESULTS: Mean total examination time was 28.0 minutes for CT fluoroscopy, 28.6 minutes for conventional CT, and 29.4 minutes for conventional fluoroscopy; mean radiologist time was 9.9 minutes, 10.5 minutes, and 9.0 minutes, respectively. These differences were not statistically significant. Mean effective radiation dose was 0.0015 mSv for conventional fluoroscopy (mean, nine sections), 0.22 mSv for CT fluoroscopy (120 kV; 50 mA; mean, 15 sections), and 0.96 mSv for conventional CT (140 kV; 240 mA; mean, six sections). Effective radiation dose can be reduced to 0.18 mSv for conventional CT by changing imaging parameters to 120 kV and 100 mA. Mean effective radiation dose of the diagnostic CT arthrographic examination (140 kV; 240 mA; mean, 25 sections) was 2.4 mSv. CONCLUSION: CT fluoroscopy and conventional CT are valuable alternative modalities for glenohumeral CT arthrography, as examination and radiologist times are not significantly different. CT guidance requires a greater radiation dose than does conventional fluoroscopy, but with adequate parameters CT guidance constitutes approximately 8% of the radiation dose.

Adolescent↗

Temporomandibular joint arthrography: comparison of morbidity with ionic and low osmolality contrast media.

We compared patient morbidity associated with temporomandibular joint (TMJ) arthrography using both meglumine/sodium diatrizoate (60%) and the new monoacidic dimer, Hexabrix, in a double-blind randomized clinical trial in 31 patients. Patients experienced maximal discomfort from TMJ arthrography with the initial joint filling and joint distension; this rapidly resolved over 10 minutes. Delayed exacerbation of pain is less than described for shoulder arthrography. The newer contrast media promise to decrease patient morbidity with arthrography.

Adult↗

Injuries of the lateral ankle ligaments: classification with tenography and arthrography.

To assess the value of tenography of the peroneal tendon sheaths and of arthrography of the tibiotalar joint for the diagnosis and classification of recent ruptures of the lateral ankle ligaments, the authors performed a prospective study on 108 patients with inversion trauma of the ankle. All patients underwent tenography. Arthrography was performed if results of tenography were negative. All patients with positive tenographic or arthrographic results underwent surgery. Tenography proved to be reliable in the diagnosis of injuries of the calcaneofibular ligament (sensitivity, 88%; specificity, 87%-94%). The positive predictive value of tenography in combination with arthrography was 100% for the diagnosis of lateral ligament ruptures. The authors conclude that a combination of arthrography and tenography is a reliable method for diagnosing recent ruptures of the lateral ankle ligaments and for differentiating between isolated ruptures of the talofibular ligament and combined lesions of both the talofibular and the calcaneofibular ligaments.

Adolescent↗

Rotator cuff disease: assessment with MR arthrography versus standard MR imaging in 36 patients with arthroscopic confirmation.

Standard proton-density- and T2-weighted magnetic resonance (MR) imaging and MR arthrography were used to depict rotator cuff disease in 36 shoulders in 36 patients; the findings were compared with arthroscopic findings in every patient. In 19 rotator cuffs normal at arthroscopy, MR arthrography revealed no tear in 16 patients, a partial tear in one patient, and a full-thickness tear in two patients. Standard proton-density- and T2-weighted images were normal in 15 of these patients and revealed a partial tear in two patients and a full-thickness tear in two patients. In 13 partial tears found at arthroscopy, MR arthrography showed a partial tear in six patients, no tear in five patients, and a full-thickness tear in two patients; standard MR imaging revealed a partial tear in one patient, no tear in 10 patients, and a full-thickness tear in two patients. All four full-thickness tears proved with arthroscopy were correctly diagnosed with both MR imaging methods. The main advantage of MR arthrography was better depiction of partial tears in the articular surface.

Adolescent↗

Posterosuperior glenoid impingement of the shoulder: findings at MR imaging and MR arthrography with arthroscopic correlation.

PURPOSE: To determine the utility of magnetic resonance (MR) imaging and MR arthrography in the evaluation of arthroscopic findings of posterosuperior glenoid impingement. MATERIALS AND METHODS: The findings at MR imaging, MR arthrography, and physical examination with the patient under anesthesia were retrospectively reviewed in eight patients with arthroscopic evidence of posterosuperior glenoid impingement. RESULTS: All patients had shoulder pain; anterior instability was found in six patients. Other than bone marrow abnormalities, findings at MR imaging were not reliable for the detection of posterosuperior glenoid impingement. MR arthrography was superior to routine MR imaging in all four cases in which it was done; positioning the shoulder in abduction and external rotation was beneficial in three of four patients. CONCLUSION: Impingement of the rotator cuff on the posterior superior glenoid labrum is a cause of posterior shoulder pain in athletes who throw. MR arthrography may allow detection of abnormalities associated with this clinical entity.

Adolescent↗

Lesions of the acetabular labrum: accuracy of MR imaging and MR arthrography in detection and staging.

PURPOSE: To determine the accuracy of magnetic resonance (MR) imaging and MR arthrography in the detection and staging of lesions of the acetabular labrum. MATERIALS AND METHODS: Fifty-seven hips of 56 patients with chronic hip pain and a strong clinical suspicion of labral lesions were examined with a three-dimensional gradient-echo sequence in the coronal oblique and sagittal oblique projections before and after the intraarticular injection of gadopentetate dimeglumine. The labra were evaluated on the basis of morphology, signal intensity, the presence or absence of a tear, and their attachment to the acetabulum. Twenty-two of the hips underwent surgical intervention, and 35 hips were treated conservatively. RESULTS: Twenty of the 22 labra with surgical proof were staged accurately with MR arthrography. On the conventional MR images, only eight of the 22 labra were staged correctly. Whereas the sensitivity of MR arthrography was 90% and its accuracy was 91%, the sensitivity of MR imaging was 30% and its accuracy was 36%, compared with surgical findings. CONCLUSION: MR arthrography enables accurate detection and staging of lesions of the acetabular labrum and appears to be indicated in the assessment of chronic hip pain in patients with a strong suspicion of labral lesions.

Acetabulum↗

Collateral ligaments of the elbow: conventional MR imaging and MR arthrography with coronal oblique plane and elbow flexion.

PURPOSE: To determine the best plane and position of the elbow for optimal visualization of normal and abnormal collateral ligaments with conventional magnetic resonance (MR) imaging and MR arthrography, to determine the normal appearance of the collateral ligaments at MR arthrography and to assess use of MR arthrography in evaluation of collateral ligamentous lesions. MATERIALS AND METHODS: Nine cadaveric elbow specimens were imaged with and without intraarticular administration of gadolinium-containing solution in several planes that were identified as potentially useful in a pilot study in two specimens. MR imaging findings were compared with anatomic findings. RESULTS: Normal and abnormal ligaments were best depicted in a 20 degrees posterior oblique coronal plane in relation to the humeral shaft with the elbows extended and a coronal plane aligned with the humeral shaft with the elbows slightly flexed (20 degrees-30 degrees of flexion). Gadolinium enhancement improved the delineation of normal and abnormal ligaments on T1-weighted images in each case. CONCLUSION: The posterior oblique coronal plane with the elbows extended or the coronal plane aligned with the humeral shaft with the elbows slightly flexed allows accurate assessment of the collateral ligaments. Gadolinium-enhanced MR arthrography of the elbow seems to be a promising technique.

Aged↗

Arthrography of the dislocated elbow joint.

Arthrography has been suggested as a useful tool for diagnosing ligament ruptures. In 14 consecutive patients with non-fractured elbow dislocations arthrography was performed after reduction of the dislocation. One or two days following arthrography all elbows were examined under general anesthesia with regard to stability and half of them were randomized for surgery with exploration and suture of both the ulnar and the radial collateral ligaments. Arthrography, even if performed within 24 hours after the injury, was found to be unreliable in diagnosing ligament injuries after elbow dislocation. Leakage of the contrast medium was more or less limited to the site of the major injury, which in the dorsal and dorso-radial dislocation was a rupture of the volar aspect of the capsule and the ulnar side of the joint in the radial dislocation.

Adolescent↗

Diagnosis of cruciate ligament injury using single contrast arthrography.

To evaluate the accuracy of arthrography for assessing the status of the anterior cruciate ligament (ACL), 212 arthrograms from 212 knees in 205 consecutive patients undergoing single contrast arthrography and subsequent arthroscopy or arthrotomy were reviewed. Criteria for evaluation of the ACL included the clarity of its radiographic appearance as well as the anterior laxity of the knee as seen on manual stress views. Of the 111 knees having intact ACLs at surgery, 98 (88%) were evaluated correctly by arthrography. Of the 101 knees having a damaged ACL, 85 were read as torn or attenuated on the arthrogram. When the torn and attenuated ligaments were considered separately, accuracy was decreased. Of the 87 ligaments actually torn, 68 (78%) were read as torn and 9 (10%) as attenuated. Of the 14 actually attenuated, 5 (36%) were read as attenuated and 3 (21%) as torn. Of 114 arthrograms read as intact, 98 (86%) were correct. Of 77 arthrograms read as torn, 68 (88%), were correct. Of 21 arthrograms read as attenuated, 5 (24%) were correct. Of 114 torn medial menisci, 112 (98%) were correctly diagnosed, as were 38 (69%) of 55 torn lateral menisci. Sixteen of the 17 missed lateral meniscus tears were in knees with torn medial menisci. Single contrast arthrography is, therefore, highly accurate in distinguishing intact from damaged ACLs. The distinction between torn and attenuated ligaments, however, is not valuable.

Humans↗

Comparison of arthroscopic findings with magnetic resonance imaging and arthrography in children with glenohumeral deformities secondary to brachial plexus birth palsy.

BACKGROUND: Characterization of glenohumeral deformities secondary to brachial plexus birth palsy with plain radiography is difficult because the glenohumeral joint does not completely ossify until puberty. The purpose of this study was to compare the findings on magnetic resonance imaging and arthrography with those on arthroscopy to better understand the roles of these methods in the evaluation of glenohumeral development in this condition. METHODS: Eighty-four children who ranged in age from seven months to thirteen years and six months had glenohumeral arthrography while they were under general anesthesia for operative treatment of an internal rotation contracture. Thirty-six children also received magnetic resonance imaging with use of cartilage-sensitive axial gradient-echo sequences. Thirty-seven children were evaluated arthroscopically. RESULTS: Arthrography showed a concentric glenohumeral joint in thirty-three children, a flat glenoid in eight, a biconcave glenoid in seventeen, and a pseudoglenoid in twenty-six. Thus, 61% (fifty-one) of the eighty-four children with an internal rotation contracture had a substantial deformity. The severity of the contracture was associated with the existence and the type of the deformity (p = 0.001). Magnetic resonance imaging showed greater detail than arthrography did in defining the severity of the deformity in both the glenoid and the humeral head. The thirty-seven children who were examined arthroscopically showed a progression from those who had a concentric, conforming joint to those who had a markedly deformed joint with a bifurcated glenoid and a flattened, oval-shaped humeral head that articulated with the posterior aspect of the glenoid. Irregularities and cavitation of the anterior aspect of the glenoid were common. The subscapularis and rotator interval tissue were the primary sites of contracture. CONCLUSIONS: Profound glenohumeral deformities secondary to brachial plexus birth palsy are commonly seen within the first two years of life. The information provided by imaging studies is helpful in defining the natural history of this condition and in determining the success of surgical intervention.

Adolescent↗

Sensitivity of MR arthrography in the evaluation of acetabular labral tears.

OBJECTIVE: MRI has historically provided suboptimal visualization of tears of the acetabular labrum. Degenerative fraying and underlying cartilage abnormalities can often mimic tears of the labrum on conventional MRI. Administration of intraarticular gadolinium enhances the MRI appearance of the labrum to improve detection of labral abnormalities. This study examined the improved diagnostic sensitivity of MR arthrography compared with conventional MRI and the importance of confining the study to a small field of view. MATERIALS AND METHODS: Fifty-one hips were imaged in 48 patients. Fourteen hips underwent conventional MRI with a large field of view (30-38 cm). Seven hips underwent conventional MRI with a small field of view (14-20 cm). Thirty hips underwent MR arthrography with a small field of view (14-20 cm). Labral tears were diagnosed when contrast material was identified within the labrum or between the labrum and the acetabulum, when a displaced fragment was noted, or when a paralabral cyst was identified. All study results were compared with findings at the time of hip arthroscopy. RESULTS: Conventional MRI with a large field of view was 8% sensitive in detecting labral tears compared with findings at the time of arthroscopy. Diagnostic sensitivity was improved to 25% with a small field of view. MR arthrography with a small field of view was 92% sensitive in detecting labral tears. CONCLUSION: A combination of MR arthrography and a small field of view is more sensitive in detecting labral abnormalities than is conventional MRI with either a large or a small field of view.

Acetabulum↗

Prearthrotomy diagnostic evaluation of the knee: review of 100 cases diagnosed by arthrography and arthroscopy.

The results of 100 prearthrotomy evaluations of the knee including clinical examinations, arthrography, and arthroscopy were correlated with surgical findings. Arthroscopy was most accurate for meniscal lesions involving the central edge and anterior horn, anterior cruciate lesions, and chondromalacia. Arthrography was most accurate for midbody and peripheral tears. The combined accuracy of arthrography and arthroscopy in diagnosing all pathology within the 100 operated knees was 97%. Our results indicate that prearthrotomy arthroscopy and arthrography are complementary examinations and not mutually exclusive.

Adolescent↗

Morbidity from shoulder arthrography: etiology, incidence, and prevention.

A prospective study was performed to assess patient discomfort after shoulder arthrography. Three different techniques were compared using equal intraarticular volumes of: positive contrast medium alone, positive contrast medium diluted with local anesthetic, or positive contrast medium and air. Moderate or severe exacerbation of baseline shoulder discomfort, when evaluated 24-48 hr after arthrography, occurred in 74% of all patients. There was significantly less discomfort after double-contrast examinations than after other techniques, although the level of morbidity was still high. This incidence and severity of discomfort after shoulder arthrography is higher than previously reported or generally recognized. Morbidity after shoulder arthrography is probably caused by a direct irritant effect of the positive contrast medium and/or the additional influx of fluid, into an already distended joint, in response to the hyperosmolar positive contrast medium. The latter effect is consistent with the delayed onset of symptoms which usually began 4-6 hr after the procedure, peaked in intensity 12 hr later and, when severe, often lasted for several days. Smaller volumes of intraarticular contrast medium and/or the use of nonionic and polymeric contrast agents, untested in this protocol, might reduce these symptoms.

Anesthesia, Local↗