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PubMedDate not supplied

[Surgical strategy in acute thrombophlebitis of the superficial veins of the lower extremities].

Active surgical policy in combined treatment of 98 patient with acute thrombophlebitis of the leg superficial veins provided good short- and long-term results in 73 of them. Urgent surgery was performed in cases with ascending thrombophlebitis of the large saphenous vein or thrombus location in the saphenofemoral anastomosis. No lethal outcome due to operative interventions were registered whereas conservative therapy resulted in 2 deaths from pulmonary artery thromboembolism.

Acute Disease↗
PubMed2004

A hematogenic pleuropneumonia caused by postoperative septic thrombophlebitis in a Thoroughbred gelding.

A 7-year-old Thoroughbred gelding was admitted to Equine Hospital, Korea Racing Association for evaluation and treatment of colic. Based on the size and duration of the large colonic and cecal impaction, a routine ventral midline celiotomy and large colon enterotomy were performed to relieve the impaction. Six days following surgery the gelding exhibited signs of lethargy, fever, inappetence and diarrhea. Eleven days following surgery, the jugular veins showed a marked thrombophlebitis. On the sixteenth day of hospitalization the gelding died suddenly. Upon physical examination, the horse was febrile, tachycardic and tachypnoeic. Thoracic excursion appeared to be increased; however, no abnormal lung sounds were detected. No cough or nasal discharge was present. Hematology revealed neutrophilic leukocytosis. Serum biochemistry was normal but plasma fibrinogen increased. In necropsy, fibrinopurulent fluid was present in the thoracic cavity. There were firm adhesions between visceral pleura and thoracic wall. White, mixed and red thrombi were formed in both jugular veins from the insertion point of IV catheter. Histopathological examination showed fibrinopurulent inflammation and vascular thrombosis in the lung. The pleura showed edematous thickening and severe congestion. The clinicopathological and pathological findings suggest that septic thrombi associated with septic thrombophlebitis metastasized into the pulmonary circulation and were entrapped in the pulmonary parenchyma and provoked pleuropneumonia.

Animals↗
PubMed2004

Haemoglobin of varicose vein, varicose vein with thrombophlebitis and in parietal thrombus of varicose vein.

Saphenous veins were taken for examination: unchanged, varicose with thrombophlebitis and varicose thrombus. The contents of haemoglobin and protein were determined in the homogenate of that material. Only small quantities of haemoglobin were found in walls of unchanged veins. Greater amounts of haemoglobin were observed in walls of varicose veins, especially in walls of varicose veins with thrombophlebitis. The varicose vein thrombus also contained marked quantities of haemoglobin.

Chromatography, Gel↗
PubMed1991

[Septic thrombophlebitis of the great vessels of the neck. A severe complication of central venous catheters].

Septic thrombophlebitis of the large veins of the neck is an uncommon, but extremely severe, complication in carriers of central venous catheters. Treatment of these cases is difficult and, generally, the clinical condition does not permit surgical approach. Four patients with septic central vein thrombophlebitis are reported. They were treated with conservative measures including catheter removal and high-dose parenteral antibiotics for at least four weeks, with excellent results in all. The relevant literature and the therapeutic alternatives are reviewed.

Adult↗
PubMed1991

Development of thrombophlebitis in peripheral veins with Vialon and PTFE-Teflon cannulas: a double-blind, randomised, controlled trial.

A series of 54 normal subjects were randomised to have either a Vialon or a PTFE-Teflon peripheral vein cannula inserted in a vein in each forearm to observe the development of thrombophlebitis. Cannulas were inspected twice daily for up to 5 days to observe the development of three signs, erythema, oedema or hardness and one symptom, pain. Each sign and symptom was recorded twice daily at three points, the cannula insertion site, the mid-point of the cannula and the cannula tip. The degree of change was recorded as less than 1, 1-2 and greater than 2 cm. Any cannula causing any sign greater than 2 cm was removed. By the end of the study over 40% of both types of cannula had been removed. There were no significant differences between the numbers of each type of cannula removed at any time point throughout the duration of the study. There were no significant differences in the amounts of erythema or hardness, but minimally increased swelling was observed at the mid-point of the PTFE-Teflon cannulas (P = 0.022). Despite the theoretical superiority of Vialon as a cannula material, under controlled conditions there appears to be little difference in its inherent capacity to cause the thrombophlebitis.

Adult↗
PubMed1990

[Acute lymphocytic leukemia with thrombophlebitis of lower limbs and translocation (4;11)].

On November 22, 1985, a 54-year-old male was admitted to the cardiovascular department of our hospital suffering from thrombophlebitis, with redness, swelling and pain around the right ankle and left knee. He was transferred to our department on Nov. 26, because of hyperleukocytosis. Peripheral blood examination revealed hyperleukocytosis with 93.0% blastic cells and thrombocytopenia. The bone marrow aspirate was hypercellular and almost all cells were consistent with peroxidase negative blastic cells. The blastic cells were Leu M1 positive and Leu M2, M3 and lymphocytic markers were negative. The patient was diagnosed to have acute lymphocytic leukemia with Leu M1 positive blast cells. BH-AC/DMP therapy was began on the 1st hospital day but he died of cerebral haemorrhage on the 4th hospital day. An autopsy revealed systemic infiltration of leukemic cells including thrombophlebitis of the legs. Chromosome analysis of the bone marrow cells showed t(4;11)(q21;q23).

Antigens, Differentiation, Myelomonocytic↗
PubMed1990

Home heparin infusion in the management of deep vein thrombophlebitis.

Feasibility of home Heparin infusion in the management of deep vein thrombophlebitis (DVT) was assessed in 15 patients. Patients with chest pain, dyspnea, bleeding tendencies, immediate postoperative state, and lack of reliable care giver were excluded. Five patients received the entire course of Heparin infusion at home and 10 were initially started on Heparin in the hospital. Regular assessment and monitoring of blood coagulation parameters were performed by a visiting home nurse clinician in consultation with the attending physician. Eleven physicians were involved in this management and made a total of six physician home visits. Results showed improvement in all but one patient, who had advanced malignancy and resistant thrombophlebitis and who eventually died. No complications occurred among the patients studied. Patient and family surveys indicated a high degree of satisfaction and preference for this modality of care. Analysis of cost indicated a 48% savings compared with similar treatment administered in a hospital setting.

Adult↗
PubMed1990

[Puerperal thrombophlebitis].

Thirty-eight cases of puerperal thrombophlebitis were reported. The incidence was 0.36% for the 1960s and 0.38% for the 1970s. During 1980s, it was reduced to 0.11%. However, the severity of the disease remained unimproved. Pulmonary and cerebral embolism occurred each in one case. Cesarean section was found to be associated with a 3-19 times increase of risk of developing puerperal thrombophlebitis as compared with vaginal delivery. The pathophysiological changes, diagnostic methods, treatment and prevention are discussed.

Adult↗
PubMed1990

[The treatment of pulmonary thromboembolism in puerperae with pelvic thrombophlebitis].

The possibilities of current conservative treatment were studied on parturients with pelvic thrombophlebitis and lung thromboembolism. It was established that performance of total hysterectomy or usage of vena cava filter in parturients with pelvic thrombophlebitis and lung thromboembolism should be made after careful evaluation and after trials of current conservative treatment (venous application of antibiotics from the sixth generation, metronidazol preparations and heparin).

Anti-Bacterial Agents↗
PubMed1988

Comparative study of the action of topical heparinoids on the evolution of experimental thrombophlebitis.

The action of three different topical heparinoids on the evolution of experimental thrombophlebitis was studied. Thrombophlebitis was induced in the marginal vein of the ear of rabbits by stasis and injection of hypertonic glucose solution. Forty-eight hours later the animals were allocated to three treatment groups and a control group. The substances were applied over the affected vein three times a day for 6 days and the ears inspected daily by transilumination. After 7 days, the animals were killed and anatomopathological studies performed. No difference in thrombus frequency or inflammatory reaction was observed between the animals treated with heparinoids and the control groups, or among the treated groups.

Animals↗
PubMed1989

[Recurrent thrombophlebitis, weakness].

The 46-year-old woman was admitted with an acute inflammatory swelling of the left forearm. During the previous six months the patient had suffered from recurrent thromboses of the superficial veins associated with generalized physical weakness. The gynaecological history was remarkable for hypermenorrhea and metrorrhagia. On examination, the signs of an acute thrombophlebitis with concomitant lymphangitis were observed. In the lower right abdomen there was a palpable tumor. Laboratory findings showed a mild anemia and indices of inflammation. Subsequent procedures (abdominal sonography, gynaecological examination) further substantiated the suspicion of an underlying malignant process. Hysterectomy and histological examination revealed two different carcinomas of the right ovary and of the uterine cave. Already during the uncomplicated postoperative period the thrombophlebitis completely regressed.

Adenocarcinoma↗
PubMed1989

[Ultrasonic scanning, is it an alternative to phlebography in deep thrombophlebitis of the leg?].

A material of 27 patients with clinically suspected deep thrombophlebitis in the lower limbs were examined both by ultrasonic scanning and by phlebography. We found a true negative diagnostic frequency of 100% and true positive diagnostic frequency of 85% by ultrasonic scanning. On the basis of this finding, ultrasonic scanning is proposed as the primary investigation in cases of suspected deep thrombophlebitis in the lower limbs.

False Positive Reactions↗
PubMedDate not supplied

A trial of povidone-iodine antiseptic solution for the prevention of cannula-related thrombophlebitis.

In a prospective trial of 200 adult patients, using a semiquantitative technique for culturing material from intravenous cannulae, we studied the efficacy of povidone-iodine antiseptic solution (test), and the use of no topical agent whatsoever (control). The incidence of cannula-related thrombophlebitis was slightly higher in the test group than in the control group. It is concluded that the use of povidone-iodine antiseptic solution does not reduce the incidence of cannula-related thrombophlebitis.

Adult↗
PubMed1989

Thrombophlebitis following intravenous glucose in the cold.

In an effort to characterize the role of carbohydrate metabolism during the hypermetabolic state associated with whole body cooling, oral (n = 6) and intravenous (iv; n = 3) glucose tolerance tests (GTT) were performed in nude subjects. Unexpectedly, 1-2 wks after the completion of their iv GTT (50% dextrose) in the cold, superficial thrombophlebitis was diagnosed in all 3 subjects. No subject developed thrombophlebitis after the oral GTT in the warm and cold, nor after the iv GTT in the warm. Since this complication was not observed in further testing with isotonic iv solutions under identical conditions in the cold as above, we conclude that the adverse reaction is the result of an interaction between whole body cooling or vasoconstriction and the hypertonicity of the dextrose solution. Environmental physiologists and medical officers should be aware of this complication.

Administration, Oral↗
PubMed1987

Postabortal septic pelvic thrombophlebitis diagnosed with computed tomography. A case report.

Septic pelvic thrombophlebitis is an uncommon complication in obstetrics and gynecology that may be difficult to diagnose clinically. Computed tomography (CT), an accurate and noninvasive modality, has greatly aided in the diagnosis of this disorder. In a case of septic pelvic thrombophlebitis complicating second-trimester pregnancy termination, CT enabled the correct diagnosis to be made and treatment to be initiated.

Abortion, Induced↗
PubMed1986

[Surgical tactics in acute thrombophlebitis of the varicose dilated great saphenous vein].

A comparative analysis of results of the operative and conservative methods of treatment of acute thrombophlebitis of varicose dilated large subcutaneous vein was performed. The conservative treatment of the disease is shown to be timetaking, does not exclude the following recidivation of the thrombotic process and operative treatment. Radical venectomy for acute thrombophlebitis of the varicose dilated large subcutaneous vein is thought to be the method of choice since it prevents developing thromboembolism of the pulmonary artery, cures the patient from the main disease and facilitates earlier occupational rehabilitation.

Acute Disease↗
PubMed1986

Widespread superficial thrombophlebitis as a manifestation of secondary syphilis--a new sign. A report of 2 cases.

Two patients with serologically proven secondary syphilis also showed multifocal superficial thrombophlebitis. All manifestations cleared when appropriate antisyphilitic treatment was instituted. Although Treponema pallidum could not be demonstrated in the thrombophlebitic veins, the organism was considered responsible, either directly or indirectly. Multifocal superficial thrombophlebitis should be regarded as a new sign of secondary syphilis.

Adult↗