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At least 199 records · Page 11Linked to original sources
PubMed1992

Behavior problems in sons and daughters of substance abusing parents.

Information to address the question of whether sex specific features exist in behavioral characteristics of children of substance abusing parents was gathered from the records of a large number of hospital treated youth. There was a trend for sons of substance abusing parents to have more conduct disorder diagnoses in association with severe aggressive/destructive behavior than sons of non substance abusing parents. Girls of substance abusing parents generally were more likely to have attention deficit/hyperactive, aggressive and conduct disorder problems than girls of non substance abusing parents.

Adolescent↗
PubMed1989

Effects of maternal mood on mother-son interaction patterns.

This study evaluated the impact of maternal mood on mother-son interaction patterns. Forty boys between the ages of 46 and 72 months and their mothers participated. A within-subject experimental design was employed so that all mothers participated in both a positive and a negative mood induction. Observations of mother-son interactions were conducted immediately following the mood inductions. During the negative mood condition, mothers issued fewer positive statements toward their children and engaged in less general verbal interaction. In addition, children were less complaint with maternal commands during the negative mood condition. Implications of the effects of mood on mother-child interaction patterns are discussed.

Adult↗
PubMed1997

Ocular manifestations in a father and son with EEC syndrome.

BACKGROUND: The ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome is a rare disease which follows an autosomal-dominant pattern of inheritance. Due to the ectodermal dysplasia there is atresia of the lacrimal duct system and aplasia of the meibomian glands with a defective tear film. Therefore, vascularized corneal scars often form during early adult life. PATIENTS: Father aged 41 years, and son aged 23 months. Both patients: stenosis/atresia of lacrimal duct systems (the father had twice undergone dacryocystorhinostomy externally) with epiphora, lip-palate clefting, syndactylies of fingers and toes, lobster deformities of hands. Additional ophthalmological findings in the father: bilaterally extracted juvenile cataracts with implantation of intraocular lenses, bilateral extensive vascularized corneal scars. Additional dermatological findings in the father: malignant melanoma of the calf, now in complete remission following several operations on the melanoma and several cycles of chemotherapy for the metastases. DISCUSSION AND THERAPEUTIC CONCLUSIONS: Father and son show the full clinical picture of the EEC syndrome with clefting, lobster-like deformities of the hands and ectodermal dysplasia with tear duct atresia and aplasia of the meibomian glands with defective tear film. During childhood, the main handicapping features are the clefting and the hand deformities with their respective multiple operative revisions. During early adulthood, however, the ocular problems become the predominantly handicapping aspects of the EEC syndrome; due to the ectodermal dysplasia, vascularized corneal scarring develops. Tearing and secondary inflammation due to lacrimal duct atresia has to be treated by early dacryocystorhinostomy. As secondary infections promote the development of corneal scars, one should not postpone the operation too long. Infections have to be treated promptly by local antibiotics. Because of the aplasia of the meibomian glands, artificial tear substitution should be given on a regular basis to support the defective tear film. Thus, the development of vascularized corneal scars can perhaps be delayed. Once corneal scarring has developed, perforating keratoplasty has a poor prognosis due to the ectodermal dysplasia, the absence of the meibomian glands and the defective tear film. Three factors lead to the formation of vascularized corneal scars: recurrent infections of lid margins and conjunctiva due to obstructed tear ducts; defective tear film with insufficient lipid phase due to the aplasia of the meibomian glands; and primary corneal epithelial defects in the course of the generalized ectodermal dysplasia.

Adult↗
PubMedDate not supplied

Sons and daughters of parents in a support organization.

Earlier surveys of a parents' support organization revealed a 3:1 ratio of parents of sons to parents of daughters. Three possible explanations for this ratio were considered based on differential onset, behavioral differences, and marital status. A re-analysis of survey data indicated that the most reasonable explanation of the gender difference is the greater propensity for anti-social behavior on the part of sons, leading to increased parental needs for support and outside assistance.

Adolescent↗
PubMed1993

Jacob Freud's birthday greeting to his son Alexander.

A new record of Jacob Freud's writing, discovered in the Freud Collections of the Library of Congress, confirms that at a late age (77) he was still involved in Hebrew learning and Judaic practice. More significantly, a letter to his youngest son, Alexander, would seem to point strongly to the latter's knowledge and practice of Judaism. This finding, in turn, would appear to complete the picture that all four of his sons, including Sigmund, had substantial Judaic training, both in school and home. It is concluded that Freud's strong, insistent denial of his Jewish education and practice is due to ulterior motives: to distance himself publicly and totally from any possible accusations--in the midst of the anti-Semitic atmosphere in Vienna and elsewhere--that psychoanalysis is Judaic. Only thus could he claim and attempt to convince others that his psychological discoveries and principles were universal and applicable to all humanity.

Adult↗
PubMed1985

Pituitary and gonadal function in the infant son of a patient with hypogonadotropic hypogonadism.

We have evaluated the pituitary-gonadal function of the infant son of a patient with hypogonadotropic hypogonadism. The father was treated with hCG and FSH to induce fertility. The son had normal external genitalia and his testicular volume increased appropriately during early infancy. Basal and post GnRH gonadotropin levels, as well as testosterone concentrations increased during early infancy. The data suggest that this infant had adequate gonadotropin secretion and testicular function. The patient illustrates the potential usefulness of evaluating the pituitary-gonadal function of male infants suspected of having hypogonadotropic hypogonadism.

Adult↗
PubMed1988

P300 latency after ethanol ingestion in sons of alcoholics and in controls.

The magnitude and persistence of ethanol-induced increases in the latency of the P3 event-related potential from auditory stimuli were evaluated in 21 sons of alcoholic fathers (FHP) and 21 control sons of nonalcoholics (FHN) matched on demography and drinking history. The men were assessed at baseline, 70 min after imbibing a beverage, and 240 min after drinking, with observations carried out for each individual in 3 dosage conditions (placebo, 0.75 ml/kg of ethanol, and 1.1 ml/kg of ethanol). There were no family group differences for baseline (prechallenge) P3 latencies, nor any significant group differences after placebo or low-dose ethanol challenges. However, in the high alcohol dose challenge condition, P3 latencies for FHP subjects returned toward baseline measures more quickly than for FHN men. These results are consistent with previous reports of behavioral and biochemical measures in which FHP subjects demonstrated less intense reactions or returned toward baseline conditions more rapidly after ethanol ingestion relative to the FHN controls.

Adult↗
PubMedDate not supplied

Mother-son sexual abuse: rare or underreported? A critique of the research.

This paper reviews the literature regarding mother-son sexual abuse and critiques the methodologies that may be responsible for the underreporting of such cases. The review of the clinical and empirical literature reveals discrepancies regarding estimates of incidence and prevalence of mother-son sexual abuse. The author suggests improved methodologies for researchers interested in studying this topic.

Adult↗
PubMed1978

An analysis of meiotic chromosomes of inbred male mice and their F1 sons after long-term treatment of sires with triethylenemelamine.

The dose-dependent effects of triethylenemelamine (TEM) on fertility and the induction of chromosomal translocation in treated mice and their F1 sons were examined C3H mice were treated with TEM for 8 successive weeks at doses of 0.02 and 0.04 mg/kg of body weight. All males treated with TEM were fertile,and cytological analysis of meiotic cells showed no chromosomal rearrangements. Semi-sterility and sterility were noted in F1 sons of TEM-treated animals. This semi-sterility and sterility were associated with reciprocal translocations. The percentage of animals heterozygous for translocations was higher for F1 males originating from sires treated with TEM at 0.04 mg/kg than from sires treated with 0.02 mg/kg.

Administration, Oral↗
PubMed1994

Tolerating reality: the experience of parents of HIV positive sons.

In this study, the experience of parents as they discover that their son is HIV+ or has AIDS, witness their deterioration and death, is described. Using the methods of grounded theory, 13 parents (8 mothers and 5 fathers) were interviewed and a model depicting the basic social psychological process (BSSP), keeping reality at a tolerable level, was developed. Six stages of tolerating reality are: Suspecting, Taking it in, Going along with the changed reality, Being swept along with symptoms, Beating down the denial, and learning to live with it. Parents engaged in a number of strategies aimed at keeping reality at a tolerable level, so they could function in their 'comfort zone' and cope with day-to-day horror, fear and uncertainty while attending to their son.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Prepubertal sons of substance abusers: influences of parental and familial substance abuse on behavioral disposition, IQ, and school achievement.

In order to better understand the transgeneration liability for a substance abuse disorder, we investigated the impact of parental and familial substance abuse disorders on prepubertal boys. Specifically, the influence of each parent's substance abuse history and the effects of significant family aggregation of substance abuse disorders were tested as predictors of the child's behavioral disposition, IQ, and school achievement scores, while controlling for socioeconomic status (SES). Sons of substance abusing fathers were found to have higher externalizing and internalizing problem-behavior scores, lower IQ scores, and lower school achievement scores. Internalizing and externalizing problem-behavior scores were most strongly associated with bilineal parental substance abuse, whereas SES and paternal substance abuse were most strongly associated with IQ and school performance scores. The results are compatible with the hypothesis that although paternal substance abuse has an adverse impact on the son's functioning, bilineal parental substance abuse is associated with the greatest behavioral deviancy among prepubertal males and is associated with a greater liability for substance abuse.

Achievement↗
PubMed2004

Engineers have more sons, nurses have more daughters: an evolutionary psychological extension of Baron-Cohen's extreme male brain theory of autism.

In his extreme male brain theory of autism, Baron-Cohen postulates that having a typically male brain was adaptive for ancestral men and having a typically female brain was adaptive for ancestral women. He also suggests that brain types are substantially heritable. These postulates, combined with the insight from the Trivers-Willard hypothesis regarding parental ability to vary offspring sex ratio, lead to the prediction that people who have strong male brains should have more sons than daughters, and people who have strong female brains should have more daughters than sons. The analysis of the 1994 US General Social Survey data provides support for this prediction. Our results suggest potentially fruitful extensions of both Baron-Cohen's theory and the Trivers-Willard hypothesis.

Adaptation, Physiological↗
PubMed2000

Concurrent choroidal melanoma in son and father.

PURPOSE: To report the concurrent occurrence of choroidal melanoma in a son and father. METHODS: Case reports. The likelihood of familial occurrence of uveal melanoma in which father and son are affected was estimated using the principles of probability. RESULTS: Unilateral choroidal melanoma was diagnosed in a 41-year-old man. Three months later, his 68-year-old father presented with a pigmented choroidal mass that greatly increased in size during the next 6 months and was diagnosed a choroidal melanoma. No personal or family history of atypical moles, cutaneous melanoma, or other malignancy existed. The likelihood of familial occurrence of uveal melanoma using principles of probability was estimated to be 1 in 10 million. CONCLUSION: Considering the low prevalence of uveal melanoma in the general population, the likelihood of uveal melanoma occurring in a family setting is remote.

Adult↗
PubMed1997

Event-related potential negative shift in sons of polysubstance- and alcohol-use disorder fathers.

Previous research has considered event-related potentials (ERPs) in relation to liability for alcohol and other substance use. This study explored ERPs in preadolescent boys at elevated risk for substance use due to paternal history of substance abuse or dependence. Sons (age 10-12) of fathers with an alcohol-use disorder (ALC, n = 29) were matched by age, IQ, education and parental alcohol use with sons of fathers with a polysubstance abuse or dependence diagnosis (POLY, n = 37). These two groups were matched with a low-risk comparison group (LOW, n = 29) of boys whose fathers had no substance-use disorder diagnosis. No boy in the study met criteria for a substance-use disorder. ERPs were collected from midline (Fz, Cz, Pz) and parietal (P3, P4) electrode leads during an auditory oddball task. ERPs of boys from the ALC and POLY groups showed a slow negative shift prominent at Cz and Pz. This negative shift, evident by 100 ms post-stimulus and lasting for the duration of the 1000-ms recording period, overlapped temporally with N1, N2 and P3 amplitude differences distinguishing the ALC and POLY groups from the LOW group. The ALC and POLY groups differed from each other in N2 amplitude at Cz, which was larger for ALC subjects. These findings offer a possible alternative explanation for previously observed amplitude anomalies noted in children at risk for substance-use disorders and suggest new avenues of inquiry.

Alcohol-Related Disorders↗
PubMed1988

[Techniques of DNA polymorphisms revealed by probes for the Y chromosome applied to questions of father-son line in analyses of paternity].

The Y specific probe (two 49f and 49a sub-clones) is a polymorphic one for the A (5 alleles), C (2 alleles), D (3 alleles), F (2 alleles) and I (2 alleles). We show that the corresponding allelic combinations, or haplotypes, are transmitted father-to-son in eleven random chosen families. Utilisation of these polymorphisms in other eleven father-son paternitity cases, studied for a panel of erythrocytic and seric markers, shows a good correlation between the two approaches, most of the paternies excluded by the Y probes being also excluded with other allotypic markers. Utilisation of this sort of polymorphism does not necessitate the knowledge of maternal genotype in families studied.

DNA Probes↗
PubMed1997

Basal plasma beta-endorphin in prepubertal sons of alcoholics and drug addicts: lack of association with problem behaviors.

Several reports have speculated that variations in beta-endorphin functioning may actually proceed the development of alcoholism and other drug use disorders, and is consequently a genetic mechanism of some etiologic importance. The goal of this investigation was to determine whether differences in basal plasma beta-endorphin concentrations could be confirmed in prepubertal children naive to alcohol and drugs, yet at parental risk for alcoholism, or drug dependence. Consequently, we have examined fasting basal plasma beta-endorphin concentrations in a sample of prepubertal sons of alcoholic fathers and compared them to both our existing sample of sons of drug dependent fathers and normal control boys. In addition, we examined the relationship between plasma beta-endorphin concentrations and maternal reports of problem behaviors posited to be related to the liability for alcoholism or drug abuse. The results reveal no differences in fasting basal plasma beta-endorphin concentrations. Although the at-risk groups differ significantly from normal boys having elevated scale scores for internalizing and externalizing problem behaviors, no association between plasma beta-endorphin and these behavioral risk factors could be found. Overall, the results fail to support an inherited 'opioid deficiency hypothesis' for the development of alcoholism or drug dependence.

Alcoholism↗
PubMed1990

'Exceptional sons' from Drosophila melanogaster mothers carrying a balancer X chromosome.

This study reports on exceptional males which are obtained by using Drosophila melanogaster mothers carrying the balancers In(1)FM6 or In(1)FM7 as one of their X chromosomes. The phenomenon was first observed in interspecific crosses between D. melanogaster females and males of its closest relatives which normally produce unisexual female hybrid progeny. Whereas hybrid sons from these crosses die as third instar larvae, the presence of the particular X balancers in the mother allows a low percentage of sons to survive. Similar sterile males are also observed among non-hybrid flies. Data are presented which suggest that the males thus generated could be hyperploid for part of their X chromosome as a result of a meiotic event in their mothers or else they could start life as female zygotes and change sex through a mitotic event at an early stage.

Animals↗
PubMed2002

Son preference and fertility in China.

This paper examines the effect of son preference on the hazards of having a second and a third birth. With data from the Two-per-thousand National Sample Survey on Fertility and Contraception conducted in 1988 by the State Family Planning Commission of China, the hazard of having a second birth among 62+ thousand married women who have had a first birth, and the hazard of having a third birth among 43+ thousand married women who have had two births was examined. These two hazards (i.e. the hazard of moving from the first to the second birth, and the hazard of moving from the second to the third birth) were analysed by estimating Cox proportional hazard models. The major covariate in the first analysis is whether or not the first-born was a daughter. In the second analysis the main covariate is whether both of the first two children were girls. In both models seven covariates known to have independent effects on the transition to a second (or third) birth are controlled for, namely, whether the woman is a Han, whether she is a farmer, her age at the birth of the first (or second) child, whether she had her first (or second) birth prior to the initiation in 1979 of the one-child policy, and three dummy variables reflecting her level of education. The results show the important influence of son preference on the hazard of having another birth.

China↗