Clinical evaluation of primidone (Mysoline), new anticonvulsant drug.
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Anticonvulsants↗
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Megaloblastic anemia during primidone (mysoline) therapy.
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Anemia↗
Intoxication from primidone due to its biotransformation to phenobarbital.
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Barbiturates↗
Controlled evaluation of primidone and diphenyllhydantoin sodium. Comparative anticonvulsant efficacy and toxicity in children.
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Adolescent↗
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
A quantitative method for the simultaneous determination of five anticonvulsants in serum has been developed using chemical ionization mass spectrometry without prior chromatographic separation. The technique was shown to be rapid, simple and sensitive, allowing the routine analysis of 50 microliter of serum with good within-day and day-to-day precision.
Anticonvulsants↗
Comparison of the effectiveness of phenobarital, mephobarbital, primidone, diphenylhydantoin, ethotoin, metharbital, and methylphenylethylhydantoin in motor seizures.
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Anticonvulsants↗
Rapid, simultaneous GLC determination of phenobarbital, primidone, and diphenylhydantoin.
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Chromatography, Gas↗
Quantitative TLC determination of primidone, phenylethylmalonediamide, and phenobarbital in biological fluids.
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Amides↗
Orthostatic tremor: combined treatment with primidone and clonazepam.
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Clonazepam↗
Placental transfer and pharmacokinetics of primidone and its metabolites phenobarbital, PEMA and hydroxyphenobarbital in neonates and infants of epileptic mothers.
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Adult↗
Synthesis of millimole amounts of 14C- and 2D-labelled primidone, phenylethylmalonamide and phenobarbital for high-sensitivity detection in biological materials.
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Biodegradation, Environmental↗
Lesions in folic acid metabolism induced by primidone.
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Biochemical Phenomena↗
Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.
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Aniline Compounds↗
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
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Benzyl Compounds↗
A gas-chromatographic method for the simultaneous determination of phenobarbitone, primidone and phenytoin in serum using a nitrogen detector.
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Chromatography, Gas↗
Quantitative determination of primidone in biological material.
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Animals↗
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.
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Animals↗
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
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Abnormalities, Drug-Induced↗