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The string and the doorknob: profile of a popular approach to dental extraction.

Dental technology and delivery of care constantly improve. At the same time, certain folk traditions and attitudes towards dentistry remain curiously constant. Dental extraction using string is an enduring amateur technique, images of which are still widely perpetuated among the laity, in western society. The historical development of extraction as a treatment modality and the rise of dentistry are discussed in relation to the patient's view of dental therapy. Various examples from art and literature are introduced to give depth and perspective to current popular perceptions. Extraction with string is presented as a metaphor for all extractions and as reflective of the public's continuing psychological sensitivity to surgical intervention in the oral cavity.

Adult↗

Binge drinking and health-related quality of life: do popular perceptions match reality?

BACKGROUND: Popular culture (movies, television shows, advertising) often portrays drinking to the point of intoxication as either humorous or associated with enjoyable social activities that enhance quality of life. This study examined the association between binge drinking (consuming five or more alcoholic drinks on one occasion) and health-related quality of life (HRQOL) among U.S. adults. METHODS: Data are from the Behavioral Risk Factor Surveillance System, a continuous random-digit-dial telephone survey of adults aged >/=18 years conducted in all states. This survey included questions about alcohol consumption and HRQOL. RESULTS: In 2001, 52% of U.S. adults were current drinkers (one or more drinks in the past 30 days). Of current drinkers, 11% were frequent binge drinkers (three or more episodes in past month) and 14% were infrequent binge drinkers (one to two episodes in past month). After adjusting for confounding factors, frequent binge drinkers were more likely than non-binge drinkers to experience >/=14 unhealthy days (physical or mental) in the past month (adjusted odds ratio [AOR]=1.39, 95% confidence interval [CI]=1.24-1.56), primarily because they had more mentally unhealthy days than non-binge drinkers (AOR=1.52, 95% CI=1.32-1.75). CONCLUSIONS: Frequent binge drinking is associated with significantly worse HRQOL and mental distress, including stress, depression, and emotional problems. Effective interventions to prevent binge drinking should be widely adopted and may help improve quality of life.

Adolescent↗

Perceptions of student nurses regarding the use of a popular autobiography as a teaching tool.

Recent studies encourage educators in nursing to use innovative and non-traditional teaching methods, such as using popular movies, posters, portfolios and surfing the internet, to stimulate students' interest, participation and interaction to enhance academic performance as well as knowledge retention. In this, descriptive cross-sectional study, we used self-administered questionnaires with statements graded on 5-points Likert scale (quantitative measures) and open-ended questions (qualitative measures), to assess the feasibility and students' perceptions regarding the use of Lance Armstrong's autobiography of surviving against cancer as a teaching tool. At the beginning of the lecture copies of selected chapters from: "It's Not About the Bike; My Journey Back to Life" [Armstrong, L., Jenkins, S. 2001. It's Not About The Bike: My Journey Back To Life. Yellow Jersey Press, Random House (Pty) Limited, Great Britain], were given to students. Willing students were requested to read for the whole class while the lecturer interjected periodically to explain and expound on certain pharmacological concepts. Eighty percent (80%) of participants felt that the use of an autobiography stimulated their interesting in cancer drugs and 84% agreed/strongly agreed that it contributed to their knowledge of pharmacology. Using Lance Armstrong's autobiography of survival to teach cytotoxic drugs is a worthwhile and rewarding exercise from the student nurses' perspective.

Adult↗

An aqueous extract of the popular Chinese nutraceutical Kwei Ling Ko (Tortoise shell-Rhizome jelly) activates the PPARgamma pathway and down-regulates the NFkappaB activity.

It is generally believed that the popular nutraceutical 'Kwei Ling Ko' (KLK; Tortoise shell-Rhizome jelly) has antiinflammatory effects, but the mechanism by which its effects are manifested remains unknown. Peroxisome proliferation-activated receptors (PPARs) are members of the nuclear hormone receptor/transcription factor superfamily with multiple roles in adipocyte differentiation, glucose homeostasis, immunomodulation and antiinflammatory regulation. As PPAR is required for adipocyte induction, we used adipogenesis as a possible screen for the activation of the PPAR pathway. Interestingly, an aqueous extract of KLK (sKLK) was able to induce the adipocyte differentiation of fibroblast cell lines. Adipogenesis was confirmed by flow cytometric analysis using a fluorescent lipid stain. Up-regulation of PPARgamma transcripts during adipogenesis was also demonstrated by reverse transcription-polymerase chain reaction (RT-PCR). The sKLK-induced adipogenesis was similar to that elicited by insulin. The activity of nuclear factor-kappaB (NFkappaB), a transcription factor responsible for the regulation of proinflammatory genes, was also down-regulated in response to sKLK. Luciferase reporter gene assays further demonstrated that sKLK inhibited both basal and tumor necrosis factor-alpha-stimulated NFkappaB activation. The activities reported in this study support an immunomodulatory effect for sKLK. As activation of PPAR pathway has a dual role in adipogenesis and anti-inflammation, our observations are consistent with the notion that KLK possesses antiinflammatory properties.

3T3 Cells↗

Antiepileptic popular ketogenic diet: emerging twists in an ancient story.

The antiepileptic activity associated with ketogenic diets (KD) have been known for some time. First reports date back to the Middle Ages and even Biblical times where KD was achieved by fasting (i.e. "water diet") [see Swink, T.D., Vining, E.P.G., Freeman, J.M., 1997. The ketogenic diet: 1997. Adv. Pediatr. 44, 297-329, and references therein]. In the early 20th century, changes in the design of the KD were introduced, shifting the so-called "water diet" to a high-fat diet. Initial clinical evaluations undertaken between the 1920s and 1940s were enthusiastic, but the popularity of the KD was retrograded upon clinical introduction of phenytoin and subsequently other antiepileptic drugs. Today, despite a pharmacological arsenal targeting cerebral receptors and specific events in seizure initiation and development, about 30-40% patients are still refractory to available medications. Thus, the KD has been re-introduced in recent years as an alternative therapy, averring to be efficacious against some instances of resistant or intractable epilepsy. Despite a long historical background and enlarged clinical use, identification of the underlying anticonvulsant mechanisms associated with this nonpharmacological approach is still in stagnation. The present review is an attempt to encourage current research orientation through well-based and directed proposals for putative emerging candidates mediating KD anticonvulsant mechanisms. The reader is provided with a special emphasis on ATP-sensitive and recently cloned two-pore (or tandem) domain potassium channels, as well as several emerging conceptual views and advances such as nuclear receptors, uncoupling proteins and gap junctions that the authors speculate may contribute to understanding the basic mechanisms linked to the KD.

Brain Chemistry↗

Popular perceptions of tobacco products and patterns of use among male college students in India.

This paper examines popular perceptions of tobacco products and describes patterns of use among college youth in Karnataka, India. Data are drawn from 25 key informant interviews and six focus groups with male and female college students, interviews with shopkeepers, observational data on youth tobacco consumption, and a college-based survey. The survey was administered to 1587 males attending eleven colleges. Forty-five percent (n = 716) of college students surveyed had used tobacco products. Thirty-six percent (n = 573) had tried cigarettes, 10% (n = 157) had tried bidis, and 18% (n = 290) had tried gutkha. Tobacco consumption among smokers was low; for daily smokers, the mean number of cigarettes smoked was 6 per day. Students attending professional colleges, including engineering, medicine, and law were significantly more likely to have ever smoked and to be daily smokers when compared to students enrolled in other courses of study. In interviews, male students noted that smoking a cigarette enhanced one's manliness, relieved boredom, and eased tension. Although female students interviewed were non-smokers, several suggested that in the future, smoking might be an acceptable behavior among college-going females. When asked about their perceptions of smoking among youth in Western countries, the majority of students believed that three-quarters of male and female youth in the West smoked. This perception has been largely formed through media images, including satellite television and films. With regard to addiction, it was widely believed that filter-tipped cigarettes were one of the most addictive products because they are made of better quality tobacco, and are milder and smoother to smoke. Therefore, a person could easily smoke more of them, which would lead to addiction. Another widely held belief was that the more expensive the cigarette, the less harmful it was for one's health.

Adolescent↗

Biotechnology and the popular press: hype and the selling of science.

The popular media has emerged as an important source of scientific information. It has been suggested that the portrayal of genetics by the media is often inaccurate--a phenomenon branded 'genohype'--and, as a result, is having an adverse impact on public understanding and policy development. However, emerging data suggest that, in some circumstances, the media reporting of science is surprisingly accurate and portrays a message created by the scientific community. As such, there are reasons to believe that the hyping of research results might be part of a more systemic problem associated with the increasingly commercial nature of the research environment.

Biotechnology↗

Evidence-based morning report: a popular new format in a large teaching hospital.

Recent innovations in postgraduate medical education place greater emphasis on evidence-based curricula and self-directed, learner-centered education. Little has been published to date about how to apply these educational innovations to morning report, traditionally an important daily teaching venue in all internal medicine training programs. We describe here the content and conduct of a new evidence-based morning report at a large teaching hospital where it has become the popular hub for residents' self-directed academic activities. Methodologic standards are needed to study, report, and evaluate outcomes of similar educational interventions.

Evidence-Based Medicine↗

Mutagenicity screening of popular Thai spices.

Mutagenicity screening was carried out on 31 samples of popular Thai spices derived from 12 different families of plants, namely the Amaryllidaceae (2), Graminae (1), Labiatae (4), Lauraceae (1), Magnoliaceae (1), Myristicaceae (2), Myrtaceae (2), Piperaceae (3), Rutaceae (2), Solanaceae (2), Umbelliferae (2) and Zingiberaceae (9). Two variations of the rapid streak method of rec-assay in Bacillus subtilis strains H17 (rec+) and M45 (rec-) were used. Only Ceylon cinnamon (the bark of Cinnamomum zeylanicum Nees of the family Lauraceae) showed mutagenic activity. The crude form of this spice and its water-heated and water-macerated residues all produced the rec effect, while water-heated and water-macerated filtrates did not, even in concentrations equivalent to as much as 50 mg solids/test disc.

Bacillus subtilis↗

Who smokes in Hollywood? Characteristics of smokers in popular films from 1940 to 1989.

We examined how smokers were depicted in 100 popular films spanning 5 decades. Smokers were depicted as more romantically and sexually active than nonsmokers and as marginally more intelligent than nonsmokers. Smokers and nonsmokers did not differ in terms of attractiveness, goodness, socioeconomic status, aggression, friendliness, or outcome at film's end. Thus, if anything, smokers are depicted a bit more positively than nonsmokers. We compared Hollywood's depiction of smokers to real-world demographics on smoking and found that Hollywood's depiction of smoking tends to ignore the negative consequences and correlates (e.g., ill health, low socioeconomic status, aggressive behavior) of smoking.

Deception↗

Popular press diagnoses and psychiatric diagnoses.

The symptom spectra of several 'popular press' diagnoses are examined and compared to Diagnostic and Statistical Manual of Mental Disorders-IIIR criteria for somatization disorder, depression, and generalized anxiety disorder. While there is much overlap, there are clear distinctions, and these psychiatric terms do not adequately coincide with the symptom spectra of these disorders. These conditions may represent 'neuroendocrine dysrhythmias' - abnormal/normal physiological dysfunctions with psychodynamic roots and/or influences. They currently often fall between the established domains claimed by Medicine and Psychiatry, with resultant poor evaluation and management with this spectrum of problems.

Female↗

Increasing popularity of injection as the route of administration of amphetamine in Edinburgh.

Six hundred and thirty four interviews of injecting drug users were performed between 1992 and 1994 as part of a study of injecting drug use and HIV prevalence in Edinburgh, Scotland. Amphetamine was injected by more subjects (44%) than any other drug. Preference for injection as the route of administration of amphetamine increased over the period despite no change in the popularity of the drug generally. Simultaneously, heroin use and injection declined. Analyses indicated that amphetamine injectors comprised two distinct sub-groups. The majority were polydrug injectors who injected frequently, had a longer injecting history and were more likely to share injection equipment. About one-fifth were stimulant-only injectors who injected infrequently, were relatively recent initiates to injecting and whose numbers increased over the 3 years. Drug treatment and prevention services may need to explore alternative methods to respond effectively to these emerging trends.

Adolescent↗

Drug policy by popular referendum: This, too, shall pass.

In formulating policies for drug offenders, lawmakers must decide concrete questions about such matters as legal jurisdiction, burdens of proof, and reporting of progress information. Although these decisions may seem incidental to treatment and beyond the purview of science, they are based on empirically testable assumptions about the behavior of drug abusers and have a direct bearing on the efficacy of drug treatment interventions. Unfortunately, these assumptions have generally not been subjected to empirical inquiry. As a result, drug policy continues to be crafted by non-scientific advocates and subjected to popular vote by an insufficiently informed public. This article identifies several empirically answerable questions that underlie critical decision points in criminal statutes for drug offenders, reviews the available research evidence relevant to these questions, and encourages drug abuse researchers to conduct studies aimed squarely at informing these policy-relevant decisions.

Comorbidity↗

An evaluation of the shape of some popular nickel titanium alloy preformed arch wires.

The mathematical Beta function is shown to be an accurate planar representation of the natural human arch form defined by the spatial coordinates of the labial and buccal dental/bracket interfacing surfaces in the maxillary and mandibular arches. Graphic planar representations of the corresponding bracket base spatial coordinates of 33 popular preformed nickel titanium arch wires and bracket assemblies were superimposed on each of the relevant maxillary and mandibular natural forms. The arch forms of the preformed nickel titanium arch wires and bracket assemblies did not emulate the natural human arch form. The average mandibular natural human arch form first molar/canine width ratio is 2.38/1; the same preformed arch wire/bracket ratio is 1.87/1. These ratios for the maxillary arch are 1.92/1 and 1.54/1, respectively. The average canine width exceeded the natural canine width by 5.95 mm in the mandibular arch and 8.23 mm in the maxillary arch. The corresponding mandibular first molar and maxillary first molar widths exceeded the natural human first molar arch width by 0.84 mm and 2.68 mm, respectively. These findings have implications with respect to posttreatment stability and facial esthetics. "Round tripping" teeth resulting from subsequent change to stainless steel arch wires to restore a more natural human arch form and size may result in deleterious tissue effects.

Cephalometry↗

Key personalities in the development and popularization of the transsphenoidal approach to pituitary tumors: an historical overview.

Although the transsphenoidal procedure, as we know it today, was devised at the beginning of the last century, its acceptance and eventual widespread affirmation have been a slow but relentless process. Like many technologic and scientific advances, several individuals contributed to the perfection of an idea whose time had come. Yet, it is unequivocally accepted that a few key figures played a critical role in the development, preservation, and eventual widespread popularization of transsphenoidal surgery. These pioneers were original thinkers and bold (albeit careful) surgeons. Their persistence in the face of incredible obstacles provides a source of continuous inspiration.

Austria↗

Health and nature in the 19th century Australian women's popular press.

This paper asks how health and nature are represented in the Australian women's press during the late nineteenth century. A time of significant social change during which women, and sympathetic male colleagues, challenged traditional roles as pathological creatures of the domestic sphere, this period is explored through the writing of women working for popular magazines. As women captured, transformed and redeployed stereotypical views of them as essentially and naturally ill, they consolidated their push into the public realm, while also convincing themselves and others of their vital place in the private sphere, but as capable, well and fit creators of people and of a nation.

Attitude to Health↗

Portrayals of food practices and exercise behavior in popular American films.

OBJECTIVE: To describe depictions of food, alcohol, and exercise and sport in popular films. DESIGN: Content analysis of the 10 top-grossing films each year from 1991 to 2000 (N = 100 films). ANALYSIS: Coding reliabilities were assessed with Cohen's kappa. Research questions were addressed with basic descriptive statistics. Associations among variables were examined through a cross-tabulation procedure that corrects for the clustering of exercise and food depictions within movies. RESULTS: Food and drink appeared regularly in the films analyzed, typically as a background element or prop. On average, food appeared on the screen once every 4.2 minutes. The foods shown were most likely to be fats, oils, and sweets; fruits, vegetables, and dairy products were rarely seen. More than 20% of the food items shown were alcoholic beverages, which were nearly 2 times more likely to be ingested as nonalcohol food items. Planned exercise and sports appeared at a rate of about 2 incidents per hour. These activities rarely received explicit evaluation by characters. CONCLUSIONS AND IMPLICATION: Films frequently portray foods and exercise. These depictions have the potential to cultivate beliefs about normative eating and exercise behavior, suggesting a need for public health professionals to encourage the media to offer healthier images.

Alcohol Drinking↗

A pneumatic artificial larynx popularized in Hong Kong.

The 'Taiwan tube' is an inexpensive pneumatic artificial larynx made in Taiwan. The device, which is a tracheo-oral shunt containing a resonator, is popular with laryngectomees in Hong Kong. This paper reports its use and describes its working dynamics which compare favourably with those of other forms of voice restoration.

Adult↗