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At least 199 records · Page 11Linked to original sources
PubMed2000

The role of gravity in human walking: pendular energy exchange, external work and optimal speed.

During walking on Earth, at 1.0 g of gravity, the work done by the muscles to maintain the motion of the centre of mass of the body (W(ext)) is reduced by a pendulum-like exchange between gravitational potential energy and kinetic energy. The weight-specific W(ext) per unit distance attains a minimum of 0.3 J x kg(-1) x m(-1) at about 4.5 km x h(-1) in adults. The effect of a gravity change has been studied during walking on a force platform fixed to the floor of an aircraft undergoing flight profiles which resulted in a simulated gravity of 0.4 and 1.5 times that on Earth. At 0.4 g, such as on Mars, the minimum W(ext) was 0.15 J x kg(-1) x m(-1), half that on Earth and occurred at a slower speed, about 2.5 km x h(-1). The range of walking speeds is about half that on Earth. At 1.5 g, the lowest value of W(ext) was 0.60 J x kg(-1) x m(-1), twice that on Earth; it was nearly constant up to about 4.3 km x h(-1) and then increased with speed. The range of walking speeds is probably greater than that on Earth. A model is presented in which the speed for an optimum exchange between potential and kinetic energy, the 'optimal speed', is predicted by the balance between the forward deceleration due to the lift of the body against gravity and the forward deceleration due to the impact against the ground. In conclusion, over the range studied, gravity increases the work required to walk, but it also increases the range of walking speeds.

Energy Metabolism↗
PubMed2001

Effects of changing gravity on anticipatory grip force control during point-to-point movements of a hand-held object.

We investigated the quality of predictive grip force control during gravity changes induced by parabolic flight maneuvers. During these maneuvers gravity varied: There were 2 periods of hypergravity, in which terrestrial gravity nearly doubled, and a 20-s period of microgravity, during which a manipulated object was virtually weightless. We determined grip and load forces during vertical point-to-point movements of an instrumented object. Point-to-point movements were a combination of static (stationary holding) and dynamic (continuous movements) task conditions, which were separately analyzed in our previous studies. Analysis of the produced grip forces revealed that grip adjustments were closely linked to load force fluctuations under each gravity condition. In particular, grip force maxima coincided closely in time with load force peaks, although these occurred at different phases of the movement depending on the gravity level. However, quantitative analysis of the ratio of maximum grip force to the corresponding load force peak revealed an increased force ratio during microgravity when compared to that during normal and hypergravity. We hypothesize that the impaired precision of force coupling with respect to force magnitude during microgravity results from reduced feedback information about the object's mass during the stationary holding of the object in between each movement. The results indicate that the temporal grip force regulation is highly automatized and stable, whereas economical planning of force magnitude is more flexible and might reflect changes of the external loading condition.

Adaptation, Physiological↗
PubMed2004

A network of superconducting gravimeters detects submicrogal coseismic gravity changes.

With high-resolution continuous gravity recordings from a regional network of superconducting gravimeters, we have detected permanent changes in gravity acceleration associated with a recent large earthquake. Detected changes in gravity acceleration are smaller than 10(-8) meters seconds(-2) (1 micro-Galileo, about 10(-9) times the surface gravity acceleration) and agree with theoretical values calculated from a dislocation model. Superconducting gravimetry can contribute to the studies of secular gravity changes associated with tectonic processes.

Journal Article↗
PubMed2006

Isolation and characterization of brewer's yeast variants with improved fermentation performance under high-gravity conditions.

To save energy, space, and time, today's breweries make use of high-gravity brewing in which concentrated medium (wort) is fermented, resulting in a product with higher ethanol content. After fermentation, the product is diluted to obtain beer with the desired alcohol content. While economically desirable, the use of wort with an even higher sugar concentration is limited by the inability of brewer's yeast (Saccharomyces pastorianus) to efficiently ferment such concentrated medium. Here, we describe a successful strategy to obtain yeast variants with significantly improved fermentation capacity under high-gravity conditions. We isolated better-performing variants of the industrial lager strain CMBS33 by subjecting a pool of UV-induced variants to consecutive rounds of fermentation in very-high-gravity wort (>22 degrees Plato). Two variants (GT336 and GT344) showing faster fermentation rates and/or more-complete attenuation as well as improved viability under high ethanol conditions were identified. The variants displayed the same advantages in a pilot-scale stirred fermenter under high-gravity conditions at 11 degrees C. Microarray analysis identified several genes whose altered expression may be responsible for the superior performance of the variants. The role of some of these candidate genes was confirmed by genetic transformation. Our study shows that proper selection conditions allow the isolation of variants of commercial brewer's yeast with superior fermentation characteristics. Moreover, it is the first study to identify genes that affect fermentation performance under high-gravity conditions. The results are of interest to the beer and bioethanol industries, where the use of more-concentrated medium is economically advantageous.

Beer↗
PubMed1992

Gravity and the circulation: "open" vs. "closed" systems.

The elementary principles of liquid dynamics are described by the equations of Bernoulli and Poiseuille. Bernoulli's equation deals with nonviscous liquids under steady streamline flow. Pressures in such flows are related to gravity and/or acceleration. Changes in elevation affect the gravitational potential energy of the liquid and the velocity of flow determines the kinetic energy. The sum of these three factors represented in the Bernoulli equation remains constant, but the variables are interconvertible. In contrast, the Poiseuille equation describes the pressures related to viscous resistance only, and the energy of flow is dissipated as heat. A combination of the two equations describes the flow in tubes more realistically than either equation alone. In "open" systems gravity hinders uphill flow and causes downhill flow, in which the liquid acts as a falling body. In contrast, in "closed" systems, like the circulation, gravity does not hinder uphill flow nor does it cause downhill flow, because gravity acts equally on the ascending and descending limbs of the circuit. Furthermore, in closed systems, the liquid cannot "fall" by gravity from higher levels of gravitational potential to lower levels of potential. Flow, up or down, must be induced by some source of energy against the resistance of the circuit. In the case of the circulation, the pumping action of the heart supplies the needed energy gradients. Flow in collapsible tubes, like veins, obeys the same basic laws of liquid dynamics except that transmural pressures near zero or below zero reduce markedly the cross-sectional area of the tube, which increases the viscous resistance to flow.(ABSTRACT TRUNCATED AT 250 WORDS)

Adaptation, Physiological↗
PubMed1999

Walking in simulated reduced gravity: mechanical energy fluctuations and exchange.

Walking humans conserve mechanical and, presumably, metabolic energy with an inverted pendulum-like exchange of gravitational potential energy and horizontal kinetic energy. Walking in simulated reduced gravity involves a relatively high metabolic cost, suggesting that the inverted-pendulum mechanism is disrupted because of a mismatch of potential and kinetic energy. We tested this hypothesis by measuring the fluctuations and exchange of mechanical energy of the center of mass at different combinations of velocity and simulated reduced gravity. Subjects walked with smaller fluctuations in horizontal velocity in lower gravity, such that the ratio of horizontal kinetic to gravitational potential energy fluctuations remained constant over a fourfold change in gravity. The amount of exchange, or percent recovery, at 1.00 m/s was not significantly different at 1.00, 0.75, and 0.50 G (average 64.4%), although it decreased to 48% at 0.25 G. As a result, the amount of work performed on the center of mass does not explain the relatively high metabolic cost of walking in simulated reduced gravity.

Aged↗
PubMed2000

Effects of respiration and gravity on infradiaphragmatic venous flow in normal and Fontan patients.

BACKGROUND: In the Fontan circulation, pulmonary and systemic vascular resistances are in series. The implications of this unique arrangement on infradiaphragmatic venous physiology are poorly understood. METHODS AND RESULTS: We studied the effects of respiration and gravity on infradiaphragmatic venous flows in 20 normal healthy volunteers (control) and 48 Fontan patients (atriopulmonary connection [APC] n=15, total cavopulmonary connection [TCPC] n=30). Hepatic venous (HV), subhepatic inferior vena caval (IVC), and portal venous (PV) flow rates were measured with Doppler ultrasonography during inspiration and expiration in both the supine and upright positions. The inspiratory-to-expiratory flow rate ratio was calculated to reflect the effect of respiration, and the supine-to-upright flow rate ratio was calculated to assess the effect of gravity. HV flow depended heavily on inspiration in TCPC compared with both control and APC subjects (inspiratory-to-expiratory flow rate ratio 3.4, 1.7, and 1.6, respectively; P:<0.0001). Normal PV flow was higher in expiration, but this effect was lost in TCPC and APC patients (inspiratory-to-expiratory flow rate ratio 0.8, 1.0, and 1.1, respectively; P:=0.01). The respiratory influence on IVC flow was the same in all groups. Gravity decreased HV flow more in APC than in TCPC patients (supine-to-upright flow rate ratio 3.2 versus 2.1, respectively; P:<0.04) but reduced PV flow equally in all groups. CONCLUSIONS: Gravity and respiration have important influences on infradiaphragmatic venous return in Fontan patients. Although gravity exerts a significant detrimental effect on lower body venous return, which is more marked in APC than in TCPC patients, the beneficial effects of respiration in TCPC patients are mediated primarily by an increase in HV flow. These effects may have important short- and long-term implications for the hemodynamics of the Fontan circulation.

Adolescent↗
PubMed1991

A technique for the determination of center of gravity and rolling resistance for tilt-seat wheelchairs.

A balance platform setup was defined for use in the determination of the center of gravity in the sagittal plane for a wheelchair and patient. Using the center of gravity information, measurements from the wheelchair and patient (weight, tire coefficients of friction), and various assumptions (constant speed, level-concrete surface, patient-wheelchair system is a rigid body), a method for estimating the rolling resistance for a wheelchair was outlined. The center of gravity and rolling resistance techniques were validated against criterion values (center of gravity error = 1 percent, rolling resistance root mean square error = 0.33 N, rolling resistance Pearson correlation coefficient = 0.995). Consistent results were also obtained from a test dummy and five subjects. Once the center of gravity is known, it is possible to evaluate the stability of a wheelchair (in terms of tipping over) and the interaction between the level of stability and rolling resistance. These quantitative measures are expected to be of use in the setup of wheelchairs with a variable seat angle and variable wheelbase length or when making comparisons between different wheelchairs.

Biomechanical Phenomena↗
PubMed2003

[Auxin-mediated response of cucumber seedlings to gravity].

Gravity regulates peg formation because cucumber seedlings grown in a horizontal position develop a peg on the lower side of the transition zone (TR zone) but not on the upper side. Studies on peg formation have suggested the regulation of peg formation by gravity as follows. Cucumber seedlings potentially develop a peg on both the lower and upper sides of the TR zone. The development of the peg on upper side of the TR zone is suppressed in response to gravity. A phytohormone, auxin, induces peg formation. Upon gravistimulation the auxin concentration on the upper side of the TR zone is reduced to a level below the threshold value necessary for peg formation. The unequally distributed auxin across TR zone is caused by a change in accumulation of auxin influx carrier (CsAUX1) protein and auxin efflux carrier (CsPIN1) protein in response to gravity. In addition, TR zone before peg initiation expresses both CsARF2 (putative activator of auxin response factor) and CsIAA1 (putative repressor of auxin-inducible gene expression), by which TR zone could respond the auxin gradient regulated by gravity.

Cucumis sativus↗
PubMed1986

Passage of inert particles varying in length and specific gravity through the postruminal digestive tract of steers.

Postruminal passage of inert particles varying in specific gravity, length, and time of administration in relation to feeding, as well as interactions among these factors, were studied in four ruminally cannulated steers. Animals were allowed access to a 40% grain mix, 60% long alfalfa hay diet for 6 h daily. Eleven combinations of particle specific gravity (.9, 1.17, 1.41, or 1.77) and length (1, 5, or 10 mm) were used. Two hundred particles of each combination were placed in the abomasum at the beginning of the meal, the end of the meal, or 6 or 12 h after the end of the meal. Recovery of particles in feces within 24 or 48 h of administration and times of first appearance and maximal concentration were examined. Particle recovery 24 h after dosing as a percentage of 48-h recovery and time of maximal concentration in feces best described postruminal passage of inert particles. Passage was affected by specific gravity, but not length, of particles. Those having a specific gravity of 1.17 passed most quickly. Time at which particles were placed in the abomasum in relation to feeding affected the passage of particles varying in specific gravity. This interaction may be important in studies of ruminal passage that depend on marker appearance in feces.

Animals↗
PubMed1999

[Errors in pointing under various body orientation relative to the gravity vector].

Errors in pointing to remembered target locations were measured in healthy subjects in upright, supine and prone positions, i.e. in three positions differing in body and arm movement orientation relative to the gravity vector. The X-error was unaffected by the body position, whereas the Y-error was dependent on subject's orientation relative to the gravity vector. In two lying positions, the subjects pointed below and in the vertical posture above the remembered target locations. On the contrary, the variable error was differentially affected by orientation of the movement trajectory relative to the gravity vector. In the supine position, the variable error was larger and in the prone position, smaller than in the upright posture. The gravity bias in pointing errors suggests that the motor program generated in the lying position is not modified to adapt to altered orientation relative to the gravity vector.

Adult↗
PubMed2000

Unique postural control of upside-down swimming catfish, Synodontis nigriventris, not affected by the change of gravity.

In general, most fishes maintain a swimming posture with the dorsal side towards the water surface under normal gravity condition. In contrast to normal fishes, a catfish Synodontis nigriventris, shows a unique postural control. The catfish keeps its posture with the ventral side towards the water surface and the dorsal side towards water bottom under normal gravity. This evidence leads one to assume that the upside-down posture of the catfish is controlled by gravity sensation in a manner different from that of other fishes. However, it has remained unclear to date whether the gravity sensation contributes to the unique postural control of this catfish. We examined its postural control in intact and labyrinth-removed catfish using a clinostat which generates a specific gravity environment (pseudo-microgravity) on earth. In addition, we examined its postural control under microgravity during parabolic flights.

Animals↗
PubMed2003

Effects of high gravity on amphibian development.

In order to clarify the possible effects of high gravity environments on eggs and developing embryos, Rana rugosa and Xenopus laevis fertilized eggs and early embryos were raised in 2 G, 5 G, 7 G and 10 G up to the hatched tadpole stage. The results showed that: (1) High gravity significantly retarded the development of eggs and embryos beginning treatment before the blastula stage and induced various abnormalities, including two heads and microcephally suggesting that high gravity is apt to disrupt the animal-vegital axis. On the other hand, embryos beginning treatment after the gastrula stage showed a striking increase in the number of normal-appearing feeding tadpoles. (2) Autopsy revealed that brains, notochords and muscles were reduced in development and differentiation for embryos and tadpoles developed in high gravity. (3) It seems likely that the system for hydrogen peroxide detoxification develops abnormally in high gravity-treated embryos and tadpoles, which probably results in oxidative stress, leading to considerable cell damage.

Animals↗
PubMed2003

Gravity or translation: central processing of vestibular signals to detect motion or tilt.

The processing and detection of tilts relative to gravity from actual motion (translational accelerations) is one of the most fundamental issues for understanding vestibular sensorimotor control in altered gravity environments. In order to better understand the nature of multisensory signals in detecting motion and tilt, we summarize here our recent studies regarding the central processing of vestibular signals during multi-axis rotational and translational stimuli. Approximately one fourth of the cells in the vestibular nuclei exclusively encoded rotational movements (Canal-Only neurons) and were unresponsive to translation. The Canal-Only central neurons encoded head rotation in canal afferent coordinates, exhibited no orthogonal canal convergence and were characterized by significantly higher sensitivities to rotation as compared to canal afferents. Another fourth of the neurons modulated their firing rates during translation (Otolith-Only cells). During rotations, these neurons typically only responded when the axis of rotation was earth-horizontal and the head was changing orientation relative to gravity. The remaining cells (approximately half of total population) were sensitive to both rotations and translations (Otolith+Canal neurons). Maximum sensitivity vectors to rotation were distributed throughout the 3D space, suggesting strong convergence from multiple semicircular canals. Only a small subpopulation (approximately one third) of these Otolith+Canal neurons seems to encode a true estimate of the translational component of the imposed passive head and body movement. These results provide the first step in further understanding multisensory convergence in normal gravity, as this task is fundamental to our appreciation of neurovestibular adaptation to altered gravity.

Acceleration↗
PubMed2004

ECG voltage modifications as response to gravity changes.

The aim of the study was to analyze ECG (QRS) voltage responses to body fluid shift due to gravity chances. Acute changes in gravity were created by two ways: 1) changes in gravity value during parabolic flights (within 27 subjects 45 ECG have been analyzed); 2) changes in gravity direction due to rotation of the body during postural tests (within 11 subjects 14 ECG have been analyzed). Results and conclusions. Gravity change leads to body fluid shift and changes of intrathoracic organs and tissues electroconduction. It influences on ECG voltage. During parabolic flights in up-right position: R amplitude in Z axis increases in hypergravity (+0.19 mV) and decreases in microgravity (-0.24 mV). During postural tests, R amplitude in Z axis increases in orthostatic position (+0.09 mV) and decreases in antiorthostatic position (-0.025 mV). Changes in QRS voltage during parabolic flights are more important than during postural tests. This could be due to more effective blood redistribution during parabolic flights.

Adult↗
PubMed1990

[A study on the relationships between imbalance of stomatognathic function and asymmetry of craniofacial morphology, and the center of gravity of the upright posture].

Mastication is one of the most important functions of the stomatognathic system and it can be performed either on the left side or right side. However, some people have each habitual chewing side, so imbalance of stomatognathic function between left and right is observed. This imbalance is supposed to reflect the relationship between the left and right elements of the stomatognathic system. Therefore, the analysis of this imbalance is very useful for assessing the stomatognathic system. The purpose of this study was to reveal the relationship between imbalance of stomatognathic function between left and right and asymmetry of craniofacial morphology, and the relationship between imbalance of stomatognathic function between left and right and center of gravity of upright posture. Eighty subjects without stomatognathic dysfunction were selected for this study. Electromyograms of the left and right masseter, anterior temporal, posterior temporal and anterior belly of digastric muscles during clenching were recorded, and mandibular movements during chewing were recorded. Analysis of imbalance between left and right was performed using functional parameters. Cephalograms (P-A) were taken for an analysis of craniofacial symmetry. The center of gravity of the upright posture was recorded using stabilograph. Analyses were performed to study the relationships between the parameters of stomatognathic function and craniofacial asymmetry, and the center of gravity of the upright posture. The results were as follows: 1. The analysis of functional parameters revealed some subjects showed imbalance between left and right sides. 2. On the side with wider craniofacial morphology as determined by some parameters, the activity of the masseter muscle during clenching showed tendency to be higher than that of the opposite, while the activity of the anterior temporal muscle showed tendency to be lower. On the side with longer craniofacial morphology, the activity of the anterior temporal muscle showed tendency to be higher than that of the opposite. 3. On the side where the center of gravity was shifted during clenching, the activities of the masseter, anterior temporal and posterior temporal muscles showed tendency to be higher than those of the opposite, and the durations of chewing cycle and opening phase showed tendency to be shorter. These results suggest that there are close relationships between imbalance of stomatognathic function and craniofacial asymmetry, and between imbalance of stomatognathic function and the center of gravity of the upright posture.

Cephalometry↗
PubMed1988

[A clinical study on lateral deviation of the line of gravity in idiopathic scoliosis].

The static deviation of the line of gravity in normal adolescent children and idiopathic scoliosis patients was analyzed. The following results were obtained: 1) The line of gravity deviated 1.3 cm to the left in the control. 2) The line of gravity in the right-convex single curve group was characterized as follows: It deviated to the right compared to the control, and it deviated further in severe cases. Brace treatment had no effect on the correction of the deviation. No difference was noted in the deviation between the thoracic and the lumbar curve group. 3) The line of gravity in the double curve group deviated slightly to the right, but that in the left convex single curve group was similar to the control. 4) The of gravity in the right-convex single curve group who underwent surgical treatment was corrected to the left.

Adolescent↗
PubMed1985

[Development of the gravity vector in normal walking. Muscular and kinetic correlations].

The vertical vector P which represents the body weight in a standing subject undergoes variations in the course of walking which merits study. This is the subject of this article. It is based on the numerical findings derived from work published on walking and is concerned with its displacement, the ground contact forces, muscular activity and expenditure of energy. A study using pressure transducers makes it possible to trace the progressive area of the gravity vector in the horizontal plane in the course of walking. At the same time, the progressive position of the centre of gravity in space can be registered and timed. The resulting trace is analogous to that obtained by a study of plantar pressures. The gravity vector is displaced in the course of walking like the clapper of a clock, suspended at the centre of gravity and passing successively in diagonal form in the four sectors of the horizontal plane defined by the axis of the walking and the frontal plane. In this displacement, its value varies steadily and cyclically. The trunk muscles, whose contraction has been studied clinically and by electromyography at the time of the different phases of walking are exactly those which can provide the mechanical compensation necessary for the displacement of the body weight vector. As to the time factor, it seems to show that, for a given subject, there exists, in relation to his weight and the height of the centre of gravity a speed of walking that corresponds to the minimum expenditure of energy.

Body Weight↗