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Fast food.

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Child↗

Fast food arthritis--a clinico-pathologic study of post-Salmonella reactive arthritis.

OBJECTIVE: To study the clinical presentation, immunogenetics, and serum immune response to lipopolysaccharide (LPS) in a cohort of patients with post-Salmonella reactive arthritis (ReA). METHODS: A validate ReA screening questionnaire (Quest 2) was mailed to 919 individuals reporting symptoms of gastroenteritis to the health department after eating at a single restaurant. Three hundred twenty-one persons returned questionnaires; 170 reported symptoms outside the gastrointestinal tract; 23 of those 170 reporting persistent joint symptoms were seen 4 to 16 weeks after the outbreak and 5 of the 23 were seen in followup 12 to 20 weeks later. Clinical features, HLA Class I typing, serum soluble CD8 levels, and serum antibodies to gram negative LPS by ELISA were determined. RESULTS: Joint complaints were reported more frequently by individuals with a longer duration of diarrhea. Upper extremity joints were frequently involved, and 66% reported one or more extraarticular symptoms of Reiter's syndrome. Three of 5 typed individuals were HLA-B27 positive, including 3 of the 4 most severely involved. Serum soluble CD8 levels correlated poorly with disease activity measured either clinically or by C-reactive protein. Antibodies to Klebsiella and Shigella LPS rose over time, while antibodies to Salmonella LPS fell. CONCLUSION: The clinical picture of post-Salmonella ReA is less stereotyped than often assumed, although severity correlated with HLA-B27 status. The association of joint symptoms with duration of diarrhea and the kinetics of the anti-LPS antibody response support the hypothesis that abnormal gut permeability plays a role in the pathogenesis of post-Salmonella ReA.

Antibodies, Bacterial↗

Efficiency of breakfast consumption patterns of ninth graders: nutrient-to-cost comparisons.

OBJECTIVE: To assess the efficiency of breakfast consumption patterns in terms of nutrient-to-cost comparisons. DESIGN: Twenty-four-hour dietary recalls were collected and food items named were priced (prices from local grocery stores and restaurants were averaged). Three breakfast consumption groups were identified: restaurant foods (fast foods), ready-to-eat (RTE) cereal, and other foods. SUBJECTS: Subjects consisted of 567 ninth-grade students (57% female, 86% white, mean age 14.8 years) in New Orleans, La. STATISTICAL ANALYSES: Analysis of variance techniques were used to test statistical significance for total nutrient intake levels, intake levels of nutrients per 1,000 kcal, and nutrient intake levels per dollar spent. Groupings were determined using the Duncan test or pairwise comparisons. RESULTS: Five percent of students ate a fast-food breakfast, 30% ate RTE cereal, and 65% ate other breakfasts. The mean cost of the breakfast meals was significantly (P<.0001) higher for the fast-food breakfast than for the RTE cereal breakfast and the other breakfast (fast>other=RTE). For every dollar spent, the RTE cereal and other breakfasts provided significantly more energy, carbohydrate, fiber, sugar, and protein than the fast-food breakfast. The other breakfast provided significantly (P<.001) more total and saturated fat per dollar than the fast-food or RTE cereal breakfasts. The RTE cereal breakfast provided significantly (P<.001) more, per dollar spent, of folic acid, iron, niacin, vitamins A and D, and zinc than the other 2 breakfast meals. APPLICATIONS: The importance consumers place on taste, cost, and convenience continues to influence types of foods consumed. Yet, their food choices may not be as efficient in terms of the nutrients obtained per dollar spent. With the increasing demands being placed on families and the decreasing amount of time being spent on food preparation, nutrition education programs should continue to promote a higher level of efficient food choices.

Adolescent↗

Seven eating styles linked to overeating, overweight, and obesity.

OBJECTIVE: To broaden the perspective on the causes of overeating, overweight, and obesity and provide cross-cultural, comprehensive treatment approaches. BACKGROUND: Through food-related research into the world's wisdom traditions, cultural traditions, Eastern healing systems, and Western nutritional science, the authors present recurrent themes derived from ways in which cultures regarded, experienced, prepared, and shared food for millennia. DESIGN: An 80-item questionnaire, designed to measure food, nutrition, and eating themes was administered to 5,256 participants who registered for a Web-based integrative nutrition e-course. When the 80-items were factor analyzed separately in two randomly split halves of the sample as well as within age and sex categories, seven coherent and consistent factors or eating styles emerged. These eating styles were entered into a multiple regression analysis to predict overeating frequency and body mass index (BMI). RESULTS: Each of the newly identified eating styles was independently related to self-reports of overeating frequency; five of the seven were significantly related to overweight and obesity. The eating styles include the following: (1) "Emotional Eating" (eating to manage feelings); (2) "Fresh Food, Fast Food" (eating mostly processed, high-calorie food; less fresh food); (3) "Food Fretting" (judgmental thoughts and overconcern about food); (4) "Task Snacking" (eating while doing other activities); (5) "Sensory, Spiritual Nourishment" ("flavoring" food with meaning); (6) "Eating Atmosphere" (dining aesthetics and surroundings); (7) "Social Fare" (eating alone vs with others). CONCLUSIONS: Further research is needed to assess the degree to which practicing and implementing these eating styles integratively will decrease overeating, overweight, and obesity.

Adult↗

Environmental and lifestyle influences on obesity.

Obesity is an end result of the intricate interactions of biology, behavior, and environment. Recent hypotheses in the scientific community suggest the current obesity epidemic is being driven largely by environmental factors (e.g., high energy/high fat foods, fast food consumption, television watching, "super-sized" portions, etc.) rather than biological ones. Individuals are bombarded with images and offers of high fat, high calorie, highly palatable, convenient, and inexpensive foods. These foods are packaged in portion sizes that far exceed federal recommendations. Furthermore, the physical demands of our society have changed resulting in an imbalance in energy intake and expenditure. Today's stressful lifestyles compound the effects of environmental factors by impairing weight loss efforts and by promoting fat storage. Combating the obesity epidemic demands environmental and social policy changes, particularly in the areas of portion size, availability of healthful foods, and promotion of physical activity.

Diet↗

[Global trends in food consumption and nutrition].

Obesity and lifestyle diseases increase all over the world, especially in developing countries. One reason is the change in diet. This nutrition transition is characterised by improvement in dietary variation, but also by increase in the content of fat and sugar. The transition seems to start at a lower level of income, compared to what occurred in the Western countries after the Second World War. The reason is that many foods are relatively cheaper, especially fat and sugar. The world market is presently flooded with cheap vegetable fat. Urbanisation leads to over-consumption by increasing market access to fatty and sugary foods, including fast foods. Globalization increases the consumption of sweet soda pops, biscuits and snacks produced by multinational companies. Western supermarkets and fast food franchises also promote these dietary changes (McDonaldization). It has been proposed that the population in developing countries is more vulnerable towards these dietary changes in regard to obesity and chronic diseases, due to undernutrition in early life (the Barker hypothesis). We may therefore expect an unprecedented increase in the prevalence of chronic diseases, especially diabetes type 2 in the developing countries. One may question if this increase will be a transient phenomenon, or if we can expect the same pattern as we have seen in the West, namely that the poor become the fat-test segment of the population, with the highest prevalence of chronic diseases.

Developed Countries↗

Effects of fasting and food restriction on sympathetic activity in brown adipose tissue in mice.

The activity of the sympathetic nervous system in mice that were either fed ad libitum, food restricted or fasted was estimated by measuring the accumulation of dopamine following the inhibition of dopamine beta-hydroxylase activity. Mice in each group were injected with the dopamine beta-hydroxylase inhibitor 1-cyclohexyl-2-mercaptoimidazole and were exposed to either 30 degrees C (warm) or 4 degrees C (cold). Mice were killed 1 h after the injection. Both heart and brown adipose tissue were then quickly removed and homogenized in ice-cold perchloric acid. Dopamine and noradrenaline were determined using high performance liquid chromatography. Regardless of whether mice were warm or cold exposed, both content and concentration of brown adipose tissue and dopamine were predictably higher in 1-cyclohexyl-2-mercaptoimidazole-injected mice than in non-injected animals. In mice fed ad libitum, post-injection content and concentration of dopamine in both brown adipose tissue and heart were higher in cold-exposed mice than in warm-exposed animals. In food-restricted and fasted mice, post-injection concentrations of dopamine in brown adipose tissue were higher in cold-exposed mice than in warm-exposed animals. In food-restricted and fasted mice there was no difference between warm- and cold-exposed animals with respect to post-injection contents and concentrations of dopamine in heart tissue. In fasted mice there was no difference between warm- and cold-exposed animals in post-injection content of dopamine in brown adipose tissue. This study provides further evidence that fasting, in contrast to food restriction, may blunt the tissue sympathetic nervous system response in brown adipose tissue of cold-exposed mice.

Adipose Tissue, Brown↗

Size makes a difference.

OBJECTIVE: To elucidate status and trends in portion size of foods rich in fat and/or added sugars during the past decades, and to bring portion size into perspective in its role in obesity and dietary guidelines in Denmark. DATA SOURCES: Information about portion sizes of low-fat and full-fat food items was obtained from a 4-day weighed food record (Study 1). Trends in portion sizes of commercial foods were examined by gathering information from major food manufacturers and fast food chains (Study 2). Data on intakes and sales of sugar-sweetened soft drinks and confectionery were obtained through nation-wide dietary surveys and official sales statistics (Study 3). RESULTS: Study 1: Subjects ate and drank significantly more when they chose low-fat food and meal items (milk used as a drink, sauce and sliced cold meat), compared with their counterparts who chose food and meal items with a higher fat content. As a result, almost the same amounts of energy and fat were consumed both ways, with the exception of sliced cold meat (energy and fat) and milk (fat). Study 2: Portion sizes of commercial energy-dense foods and beverages, and fast food meals rich in fat and/or added sugars, seem to have increased over time, and in particular in the last 10 years. Study 3: The development in portion sizes of commercial foods has been paralleled by a sharp increase of more than 50% in the sales of sugar-sweetened soft drinks and confectionery like sweets, chocolate and ice creams since the 1970s. CONCLUSIONS: Larger portion sizes of foods low in fat and commercial energy-dense foods and beverages could be important factors in maintaining a high energy intake, causing over-consumption and enhancing the prevalence of obesity in the population. In light of this development, portion size ought to take central place in dietary guidelines and public campaigns.

Adolescent↗

Meal size, not body size, explains errors in estimating the calorie content of meals.

BACKGROUND: Although most people underestimate the calories they consume during a meal or during the day, calorie underestimation is especially extreme among overweight persons. The reason for this systematic bias is unknown. OBJECTIVE: To investigate whether the association between calorie underestimation and body mass reflects a tendency for all persons to underestimate calories as the size of a meal increases. DESIGN: Overweight and normal-weight adults estimated the number of calories of a fast-food meal they had ordered and eaten (study 1) or of 15 fast-food meals that were chosen by the experimenter (study 2) in a randomized, controlled trial. Their estimations were compared with the actual number of calories of the meals. SETTING: Study 1 was a field study conducted in fast-food restaurants in 3 medium-sized midwestern U.S. cities. Study 2 was conducted in a laboratory at a major U.S. research university. PARTICIPANTS: Study 1 involved 105 lunchtime diners (average body mass index [BMI], 24.2 kg/m2 [range, 17.2 to 33.5 kg/m2]). Study 2 involved 40 undergraduate students (average BMI, 23.2 kg/m2 [range, 16.1 to 32.3 kg/m2]). MEASUREMENTS: Participants were asked to estimate the number of calories in a fast-food meal they had ordered and eaten (study 1) or in 15 sizes of the same fast-food meal (study 2). The actual number of calories in the meals in the field study was obtained by unobtrusively recording the food that was ordered (identified from the wrappings and containers). Weight and height were self-reported. RESULTS: Although participants strongly underestimated the number of calories in larger meals (by -38.0% in study 1 and by -22.6% in study 2), they almost perfectly estimated the number of calories in smaller meals (by -2.9% in study 1 and by 3.0% in study 2). After the authors controlled for body weight-related differences in meal size, the calorie estimations of normal-weight and overweight participants were identical in both studies. LIMITATIONS: These studies examined fast-food meals. Weight and height were self-reported. There were too few observations to distinguish between obese (BMI > or =30 kg/m2) and overweight (BMI >25 kg/m2 but <30 kg/m2) participants. CONCLUSIONS: Greater underestimation of calories by overweight persons is a consequence of their tendency to consume larger meals. Calorie underestimation is related to meal size, not body size.

Adult↗