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At least 199 records · Page 11Linked to original sources
PubMed1984

Changes in the rheologic properties of blood after a high altitude expedition.

The changes in blood rheologic properties induced by exposure to high altitude plus heavy and prolonged physical strain were investigated in 14 climbers of an Italian expedition to Himalaya (maximum altitude reached m 7350). In blood samples collected immediately after return, alterations of some haemorheologic parameters were observed in comparison with baseline values, and namely an increase in relative blood viscosity, fibrinogen and erythrocyte filtration time along with a fall in platelet count. Treatment with a drug acting on the red cell deformability (Pentoxifylline) appeared to prevent the changes in blood viscosity and erythrocyte filterability. In the 9 climbers whom we were able to re-examine after three months, all altered parameters were found to be restored to baseline values. These results contribute to the knowledge of the pathogenesis of high altitude disease and stress the significance of altered haemorheology as one of the mechanisms possibly involved in the vascular events observed in this condition.

Adult↗
PubMed2006

Expedited laser damage profiling of KDxH(2-x)PO4 with respect to crystal growth parameters.

We investigate the laser-induced damage resistance at 355 nm in deuterated potassium dihydrogen phosphate (DKDP) crystals grown with varying growth parameters, including speed of growth and temperature. The aim is to explore a new expedited method to study the growth parameters affecting the laser-induced damage resistance in DKDP material to obtain crystals with enhanced performance.

Journal Article↗
PubMed2001

Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICU.

STUDY OBJECTIVE: To determine if enterally administered methadone can facilitate fentanyl discontinuation and prevent withdrawal in children at high risk for opioid abstinence syndrome. DESIGN: Retrospective analysis. SETTING: Pediatric intensive care unit (PICU) in a tertiary care children's hospital. PATIENTS: Twenty-two children (aged 6.1 +/- 5.4 yrs) who received continuous fentanyl infusion for 9 days or longer. INTERVENTION: Guidelines for initiating enteral methadone, rapidly tapering and discontinuing fentanyl infusions, and tapering methadone were implemented in the PICU. Development of opioid abstinence syndrome was evaluated during fentanyl and methadone dosage reductions and for 72 hours thereafter. MEASUREMENTS AND MAIN RESULTS: Children received fentanyl by continuous infusion for 17.8 +/- 8.4 days. Peak fentanyl infusion rate was 5.9 +/- 3.8 microg/kg/hour, and the median cumulative dose was 1302 microg/kg (range 354-7535 microg/kg). Methadone 0.50 +/- 0.22 mg/kg/day was begun 1.6 +/- 1.9 days before tapering fentanyl. The fentanyl infusion rate on starting the taper was 5.0 +/- 3.6 microg/kg/hour. Fentanyl was tapered and discontinued in a median of 2.6 days (range 0-11.9 days). Twenty-one patients had no opioid abstinence syndrome during or after fentanyl taper. One patient experienced significant opioid withdrawal after fentanyl discontinuation, which resolved after reinstitution of fentanyl and increasing the dosage of methadone to 0.3 mg/kg every 6 hours. Overall, methadone was tapered and discontinued in 18.2 +/- 11.9 days without precipitating opioid abstinence syndrome. CONCLUSION: Enteral administration of methadone may expedite fentanyl discontinuation and reduce the risk of withdrawal in critically ill children at high risk for opioid abstinence syndrome.

Adolescent↗
PubMed2004

Comparison of the RT3 Research Tracker and Tritrac R3D accelerometers during a backpacking expedition by a single subject.

This study compared the RT3 Research Tracker accelerometer and the Tritrac R3D accelerometer in a field setting. A six-day backpacking expedition (122.4 km in length) was completed by a single subject in the Grand Canyon National Park, Arizona. The overall correlation between the counts of vector magnitude activity for the RT3 and R3D was moderate (r =.75, p<.001), with the overall calculated bias [mean difference (RT3 minus R3D) and standard deviation of the differences] across all six days estimated at 235+/-436 vector magnitude activity counts. However, agreement between the instruments is problematic; the RT3 might be 201 activity counts below or 671 activity counts above the R3D in assessing physical activity during backpacking.

Acceleration↗
PubMed2004

Morbidity and health survey of wintering members in Japanese Antarctic research expedition.

STUDY DESIGN: The Japanese Antarctic Research Expedition (JARE) started in 1956. Syowa Station is the mother station of JARE at 69 degrees 00'S and 39 degrees 35'E in East Antarctica. An epidemiological survey of the wintering team of JARE was carried out based on the annual reports of JARE over the period 1956-2001. METHODS: The total number of personnel was 1,236 including 3 females. The age of personnel was from 21 to 56 (average 33.1). We examined the proportion of personnel who had contracted disease with healthy personnel, as reported by the medical department at Syowa as well as a health survey of the latest party by biochemical analyses. RESULTS: The total number of diseases was 4,760. The ratios of surgical-orthopedic, internal medical, and dental cases were 45%, 23%, and 13%, respectively. Only one death from a blizzard was recorded. In the latest party, serum levels for triglyceride, calcium, and gamma-glutamyl transpeptidase increased during the wintering period. CONCLUSION: The very low mortality of JARE may be due to the effective personnel selection and that there have been no severe accidents. There has been no deterioration in nutritional parameters in JARE recently.

Adult↗
PubMed1997

Medicare program; establishment of an expedited review process for Medicare beneficiaries enrolled in health maintenance organizations, competitive medical plans, and health care prepayment plans--HCFA. Final rule with comment period.

This final rule with comment period establishes a new administrative review requirement for Medicare beneficiaries enrolled in health maintenance organizations (HMOs), competitive medical plans (CMPs), and health care prepayment plans (HCPPs). This rule implements section 1876(c)(5) of the Social Security Act, which specifies the appeal and grievance rights for Medicare enrollees in HMOs and CMPs. This rule requires that an HMO, CMP, or HCPP establish and maintain, as part of the health plan's appeals procedures, an expedited process for making organization determinations and reconsidered determinations when an adverse determination could seriously jeopardize the life or health of the enrollee or the enrollee's ability to regain maximum function. This rule also revises the definition of appealable determinations to clarify that it includes a decision to discontinue services.

Centers for Medicare and Medicaid Services, U.S.↗
PubMed1998

Expedited safety reporting requirements for human drug and biological products; correction--FDA. Final rule; correction.

The Food and Drug Administration (FDA) is correcting a document that appeared in the Federal Register of October 7, 1997 (62 FR 52237), to include some conforming amendments that were inadvertently omitted. The final rule amended the expedited safety reporting regulations for human drug and biological products. This action is being taken to ensure the accuracy and consistency of the regulations.

Adverse Drug Reaction Reporting Systems↗
PubMed1982

Medicare program; Provider Reimbursement Review Board: expedited administrative review--Health Care Financing Administration. Final rule with comment period.

Current Medicare regulations permit providers of services to appeal reimbursement decisions of Medicare fiscal intermediaries to the Provider Reimbursement Review Board. Following the Board's decision, the provider may also request judicial review of that decision (and of any action by the Secretary with respect to that decision). These amendments to our regulations permit the provider to obtain expedited administrative review when the Board determines that it lacks authority to decide a question of law, regulation, or HCFA ruling relevant to the case. The question of whether authority is lacking may be raised by the provider or on the Board's own motion. The regulations eliminate the current requirement for a Board hearing before judicial review when the Board lacks authority to decide an issue, and they establish time limits within which the Board must act. These rules implement section 955 of the Omnibus Reconciliation Act of 1980, Pub. L. 96-499.

Centers for Medicare and Medicaid Services, U.S.↗
PubMed1983

Medicare program; Provider Reimbursement Review Board; expedited administrative review--HCFA. Final rule.

These regulations amend procedures for providers to follow in order to obtain an expedited administrative review where the amount of Medicare reimbursement is in dispute. The changes are in response to comments we received on our final rule with comment period, published July 22, 1982. They are intended to clarify policy not included specifically in previous regulations text.

Centers for Medicare and Medicaid Services, U.S.↗
PubMed1999

[Recovery and use of deuterium-free water in extended space expeditions].

The methods of deuterium-free water, as applied to the conditions of long-term space expeditions have been discussed. It is shown that with the use of the method of electrolysis of distilled water or urine condensate followed by the catalytic or high-temperature synthesis one can obtained water with four-fold decrease in deuterium concentration. In order to reduce the energy expenditure it is necessary to use the existing routine technologies of water and oxygen regeneration or the versions with applying the fuel cells in which hydrogen and oxygen resulting from electrolysis would generate the electrical power with simultaneous isolation of deuterium-free water.

Deuterium↗
PubMed1999

Kangchenjunga 1998. A venture undertaken with "medical expeditions".

The article describes the research carried out on the recent Kanchenjunga Medical Expedition to Eastern Nepal during the post-monsoon season of 1998. Twenty-two projects are described, under the general functional headings of respiratory, cardiovascular, hormonal, sensory and neurological and infection and immunity.

Acclimatization↗
PubMed2000

Expediting the transfer of evidence into practice: building clinical partnerships.

A librarian/clinician partnership was fostered in one hospital through the formation of the Evidence-based Practice Committee, with an ulterior goal of facilitating the transfer of evidence into practice. The paper will describe barriers to evidence-based practice and outline the committee's strategies for overcoming these barriers, including the development and promotion of a Web-based guide to evidence-based practice specifically designed for clinicians (health professionals). Educational strategies for use of the Web-based guide will also be addressed. Advantages of this partnership are that the skills of librarians in meeting the needs of clinicians are maximized. The evidence-based practice skills of clinicians are honed and librarians make a valuable contribution to the knowledge-base of the clinical staff. The knowledge acquired through the partnership by both clinicians and librarians will increase the sophistication of the dialogue between the two groups and in turn will expedite the transfer of evidence into practice.

Evidence-Based Medicine↗
PubMed2001

[Specific aspects of hemostasis and lipid peroxidation in thrombocyte membranes during expedition and shift organization of labor].

The aim of the present study is to investigate dynamics of the hemostasis system and structural and functional state of thrombocyte membranes by the LPO and AOD parameters under the conditions of expedition and shift organization of labour of worker tripping from the West Siberia middle latitudes to the Far North. A trend to hypocoagulemia and increases in LPO and AOD reactions were characteristic of the type-1 (adaptive) reaction. The type-2 (hypotensive) reaction included a trend to hypercoagulemia, an increase in LPO and a decrease in AOD reactions in thrombocyte membranes as well as a hypertensive reaction during the whole shift period. The type-3 (asthenic) reaction was described by hypocoagulemia, an increase in the amount of LPO products with a simultaneous decrease in the AOD activity and asthenic sleep disturbance.

Adult↗
PubMed1995

[The herbariums from Spanish scientific expeditions in the New World].

The herbaria compounded by the botanical Spanish expeditions to the New world during the XVIIIth century constitutes one of the most important treasures of the Royal Botanical Garden from Madrid. These collections of dry plants document the existence of the species in time and in space, and they are essential resources for the botanical investigation. The specimens type and of reference of these collections are fundamental for the correct identification of each species and their varieties. They are used to give validity to the botanical investigation securing that one could repeat or compare with future investigations.

Americas↗
PubMedDate not supplied

Expedited permanency planning: evaluation of the Kentucky Adoptions Opportunities Project.

This article presents the evaluation findings of a Kentucky Adoptions Opportunities Project (KAOP), a three-year project funded by the U.S. Department of Health and Human Services, Administration on Children, Youth and Families, Children's Bureau. The primary goal of the KAOP was implementation of three permanency planning activities: (1) risk assessment/concurrent planning, (2) one child/one legal voice, and (3) early placement in kinship or foster/adoptive homes. These activities were designed to expedite a permanency placement decision within 12 months for high-risk children. The evaluation of 124 high-risk children in the KAOP revealed that the majority of children had one or both parents coping with multiple risk factors, including mental illness, substance abuse, mental retardation, or family violence. The major barriers to permanency are discussed, as well as the policy and practice implications in the context of Adoption and Safe Families Act of 1997.

Adoption↗
PubMed1998

[An experimental study of expediting the early attachment of human gingival epithelial cells to titanium with laminin].

Using in vitro culture model, the attachment of human gingival epithelial cells to laminin-coated pure titanium was studied. The average numbers of attached cells on different surface of titanium with or without laminin were calculated under catoptric fluorescent microscope and were statistically analyzed with factorial design. The results showed that Laminin could expedite the early attachment of human gingival epithelial cells to titanium.

Cell Adhesion↗
PubMed2002

["P" as in Program Package. About torturing data and significant "fishing expeditions"].

For the study of prognostic factors, the medical researchers have access to a number of advanced statistical techniques available in standard program packages. A tradition has developed where survival or time to relapse is analysed on the basis of statistical materials with few patients but a large number of possible explanatory variables. In statistical "fishing expeditions" the p-values are used to sort out potentially useful prognostic variables. Since the number of observations is small, all relevant prognostic factors do not give statistical significance. Since a large number of variables are tested there is a considerable risk for spurious significances. It is not enough to show that a prognostic factor seems to be efficient in the patient group where it was first found. The result must be verified in further studies of independent groups of similar patients.

Confidence Intervals↗