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At least 199 records · Page 11Linked to original sources
PubMed1975

[Histological classification of malignant breast neoplasms. Recent concepts].

The recent histological classifications of breast malignant epithelial tumours place increased emphasis on several concepts: in situ carcinoma, difference of lobular carcinoma from other forms of breast cancer and histological factors of prognosis. The authors propose to discriminate: non infiltrating duct carcinoma (intraductal carcinoma); lobular carcinoma (in situ and infiltrating); infiltrating duct carcinoma in their usual form (80 p. 100 about of all breast carcinoma); among them, histological types with a less ominous prognosis, although relatively rare, are stressed (infiltrating papillary and comedo-carcinomas, tubular carcinoma, medullary carcinoma, colloid carcinoma, cylindroma, certain metaplastic variants, Paget's disease of the nipple); some features in unusual hosts are related. They mention the criteria of the Scarff and Bloom's "grading" and its importance from the point of view of prognosis, mainly for the usual infiltrating forms. Other malignant tumours of the breast (malignant cystosarcoma phyllodes, sarcomas, mammary metastases) are more scarcely seen (I p. 100 of the mammary neoplasms): their classification is succinctly recalled.

Breast↗
PubMedDate not supplied

[Correlation of the probability of occurrence of breast neoplasms with solar activity].

A contingent with high incidence of precancerous breast diseases (1080 persons) was studied to assess the relationship between solar activity and 1) alterations in the relationship between women with early menarche and women with middle and late menarche (high and low risk of breast cancer respectively) and 2) incidence of benign breast diseases. It was established that population content alterations were wave-like and had statistically significant periods 3,5; 7 and 12 years, and correlate with Wolf number changes. Incidence of benign breast diseases in the group aged 20-50 years also changed periodically (T = 11 years) depending on the birth-year and correlated conversely with Wolf numbers at the birth-years. Incidence of benign breast diseases changes periodically in the population of women with early menarche with the period of 3.6 years, and in those with middle and late menarche--with the periods of 10.5, 3.2 and 4 years. There is a statistically significant correlation between the incidence of benign breast diseases and Wolf numbers in population of women with middle and late menarche.

Breast Diseases↗
PubMed1984

[Estrogen receptors in primary breast neoplasms].

Estrogen receptors were studied in 108 stage I and II breast cancer patients aged 28-83. The receptors were identified in 72.6% of cases, 55.5% of tumors being estrogen receptor-positive. Estrogen receptor level and frequency in tumor were found to depend upon patient's age and menstrual function. Mean estrogen receptor levels in patients with adrenal and involutive forms of cancer, which are the most sensitive to hormone therapy were 2-3 times those in ovarian and thyroid forms, the latter being the least sensitive to hormone treatment (ovariectomy + corticosteroids). Scirrhous tumors of the breast in elderly patients were mostly estrogen receptor-positive, this pointing to favorable prognosis in this age bracket.

Adenocarcinoma↗