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PubMed1991

Zona incerta lesions: effects on copulation, partner-preference and other socio-sexual behaviors.

Sexually active males prefer a sexually receptive female to a non-receptive female, and partner-preference tests provide one way of studying the effect of brain damage on sexual motivation. Male rats with bilateral electrolytic lesions of the caudal zona incerta do not mate, and we studied the effects of zona incerta destruction on copulation and partner-preference. Lesioned males did not mate but were not indifferent to sexually receptive females. They continued to show a strong preference for a sexually receptive female over a non-receptive female. In addition, lesioned males showed many incomplete mounts i.e. mounts not accompanied by the pelvic thrusting necessary for intromission and ejaculation. Anogenital investigation of the receptive female was common. Taken together, these facts suggest that zona incerta destruction eliminates copulation without affecting sexual motivation, and that the failure to mate after lesioning probably reflects an inability to properly engage the locomotor responses of copulation.

Animals↗
PubMed1988

Ontogeny of polycose and sucrose appetite in neonatal rats.

Rat pups 3 to 15 days of age were infused with sucrose or Polycose solutions (.03 or .3 M) through oral cannulas and their solution intake, mouthing behavior, and general locomotor activity were recorded. Overall, the pups displayed similar ingestive responses to Polycose and sucrose. They discriminated between .3 M sucrose and water as early as 6-days of age, and between .3 M Polycose and water as early as 9-days of age. However, at the .03 M concentration the pups responded to Polycose before they responded to sucrose. The results confirm previous reports that rat pups have an unlearned preference for sucrose and demonstrate that a similar preference exists for starch-derived polysaccharides. The Polycose appetite displayed by the neonatal rats is consistent with results obtained with adult animals which suggest that rats have taste receptors for starch-derived polysaccharides as well as for sugars.

Aging↗
PubMed2005

Does brand differentiate pharmaceuticals?

INTRODUCTION: Role of marketing in pharmaceutical industry is increasing and inspiration by successful brands known from consumer goods market influenced pharmaceutical companies enough to switch their attention to branding initiatives. Still there is little evidence that pharmaceutical brands represent anything more than product only. OBJECTIVES AND METHODS: This study aims to explore the area of branding in pharmaceutical industry. Central hypothesis of the research has been that brand and its emotional content differentiate pharmaceuticals as well as rational data derived from clinical studies. It has been tested by extensive review of available literature as well as by primary research focused on drivers of physicians' attitudes towards products and their influence on prescribing behavior. The research has been conducted in the sample of psychiatrists in the Czech Republic. RESULTS: No evidence about pharmaceutical brand exceeding value of product has been found in reviewed literature. Nevertheless, the primary research conducted in the sample of Czech psychiatrists indicates that emotional brand in pharmaceutical industry exists and enables author to draw a model of Customer/product life cycle that describes likely impact of functional, emotional and self-expressive benefits throughout pharmaceutical product's market presence. CONCLUSIONS: Pharmaceutical brand is likely to develop differently than the same of consumer goods products--it seems to be built predominantly on long-term positive experience. Marketing role in this process should lie in finding relevant product position and building brand identity compliant with real product capabilities.

Advertising↗
PubMed2005

The effect of Taiwan's tax-induced increases in cigarette prices on brand-switching and the consumption of cigarettes.

The effect of raising cigarette taxes to reduce smoking has been the subject of several studies, which often treat the price of cigarettes as an exogenous factor given to smokers who respond to it by adjusting their smoking behavior. However, cigarette prices vary with brand and quality, and smokers can and do switch to lower-priced brands to reduce the impact of the tax on the cost of cigarettes as they try to consume the same number of cigarettes as they had before a tax hike. Using data from a two-year follow-up interview survey conducted before and after a new cigarette tax scheme was imposed in Taiwan in 2002, this study examines three behavioral changes smokers may make to respond to tax-induced cigarette price increase: brand-switching, amount consumed, and amount spent on smoking. These changes were studied in relation to smoker income, before-tax cigarette price, level of addiction, exposure to advertizing, and consumer loyalty. We found that smokers, depending upon exposure to advertizing, level of consumer loyalty and initial price of cigarettes, switched brands to maintain current smoking habits and control costs. We also found that the initial amount smoked and level of addiction, not price, at least not at the current levels in Taiwan, determined whether a smoker reduced the number of cigarettes he consumed.

Adolescent↗
PubMed1996

Why do bad moods increase self-defeating behavior? Emotion, risk taking, and self-regulation.

Increased risk taking may explain the link between bad moods and self-defeating behavior. In Study 1, personal recollections of self-defeating actions implicated bad moods and resultant risky decisions. In Study 2, embarrassment increased the preference for a long-shot (high-risk, high-payoff) lottery over a low-risk, low-payoff one. Anger had a similar effect in Study 3. Study 4 replicated this and showed that the effect could be eliminated by making participants analyze the lotteries rationally, suggesting that bad moods foster risk taking by impairing self-regulation instead of by altering subjective utilities. Studies 5 and 6 showed that the risky tendencies are limited to unpleasant moods accompanied by high arousal; neither sadness nor neutral arousal resulted in destructive risk taking.

Adolescent↗
PubMed2003

Is there a magnitude effect in tipping?

The present study examined nearly 1,000 tips recorded for two taxicabs, two hair salons, and two restaurants. In each of the six cases, amount of tip increased linearly as a function of the amount of the bill. Contrary to standard microeconomic theory, there was a magnitude effect in that as the amount of the bill increased, the percent tip tended to decrease. The present results extend the findings of Chapman and Winquist (1998), obtained using hypothetical scenarios, to real-world tipping behavior. Chapman and Winquist argued that a magnitude effect in tipping reflects the shape of the utility function for money. We suggest, however, that the magnitude effect may be the mathematical consequence of replotting the fundamental relationship between tip and bill amounts in terms of percent tip, given that the observed linear relation between tip and bill amounts has a positive intercept. We suggest further that the positive intercept arises because a tip represents a judgment as to what constitutes a fair or equitable wage, and part of what constitutes a fair wage is independent of the amount of the bill, reflecting compensation for simply being there when needed. The present account implies that different explanations may be needed for magnitude effects observed in different domains.

Choice Behavior↗
PubMed2006

Spatially selective representations of voluntary and stimulus-driven attentional priority in human occipital, parietal, and frontal cortex.

When multiple objects are present in a visual scene, they compete for cortical processing in the visual system; selective attention biases this competition so that representations of behaviorally relevant objects enter awareness and irrelevant objects do not. Deployments of selective attention can be voluntary (e.g., shift or attention to a target's expected spatial location) or stimulus driven (e.g., capture of attention by a target-defining feature such as color). Here we use functional magnetic resonance imaging to show that both of these factors induce spatially selective attentional modulations within regions of human occipital, parietal, and frontal cortex. In addition, the voluntary attentional modulations are temporally sustained, indicating that activity in these regions dynamically tracks the locus of attention. These data show that a convolution of factors, including prior knowledge of location and target-defining features, determines the relative competitive advantage of visual stimuli within multiple stages of the visual system.

Adult↗
PubMed1997

Food shopping and label use behavior among high school-aged adolescents.

Ninety adolescents (41 males and 49 females) stratified by shopping experience (44 shoppers and 46 nonshoppers) were given a list of 20 foods to select in a supermarket. An interview was conducted to determine reason(s) given for each food selection, use of nutrition information, and other variables. Reasons most often reported for selecting foods were personal preference/taste, custom/habit, and price/cost. Participants were five times more likely to use front label/nutrition claims than nutrient labels. Fat free/low fat, lite/light, and cholesterol free/low cholesterol were the most commonly used claims whereas total fat and calories were the most commonly used nutrient label constituents. Females were more likely than males to use front label/nutrition claims (F (1,82) = 4.78, p < .01). There were no significant differences between males' and females' use of nutrient labels. Education that emphasizes food-shopping and label-reading skills is needed by adolescents.

Adolescent↗
PubMedDate not supplied

[Spatial-motor asymmetry in rat behavior].

The experiments were carried out on rats in three different mazes: U-shape, complicated linear and 12-beam radial. Series of tests differed by succession of rats learning in the mazes and the character of reinforcement. Most of the rats manifested a spatial-motor asymmetry (SMA) in all used situations. Under all conditions SMA increased in the process of learning parallel to a decrease of the errors number or the time of the task performing. In the group of rats sequently learning in different mazes, the direction of moving changed with changes in spatial characteristics of the medium. Preliminary training of rats in conditions creating SMA, promoted its acceleration in new conditions. The conclusion is made that the rats have no physiological mechanism which rigidly fixes a single (in all conditions) direction of runs. SMA is considered as a behavioural tactics which is corrected in the process of training and which provides for an adequate behaviour.

Animals↗
PubMed2003

Stimulus control of predatory behavior by the Iberian wall lizard (Podarcis hispanica, Sauria, Lacertidae): effects of familiarity with prey.

The authors examine the relative roles of vision and chemoreception and the influence of previous experience with prey on the predatory behavior of Iberian wall lizards (Podarcis hispanica). Experiment 1 compared the responses to visual, chemical, and a combination of visual and chemical cues of a familiar prey by 2 groups of lizards that had been kept in captivity for either 3 months or 21 days. Experiment 2 assessed the responses of lizards kept in the laboratory for more than 3 months to a novel prey species. The results reveal that feeding on a prey species affects the lizards' responses to chemical stimuli from that prey. The response to chemical cues of a novel prey requires a 1st-feeding experience with that prey. Lizards that have been fed the same prey species for several months cease responding to the chemical stimuli of that particular prey.

Animals↗
PubMed1976

Experimental studies on food selective behavior in squirrel monkeys fed on riboflavin deficient diet.

The present study was conducted to determine the extent to which squirrel monkeys might demonstrate self-selective behavior when fed a riboflavin deficient diet, and the extent to which such a diet might lead to digestive disturbances, general weakness, lack of vigor, and loss of weight for such animals. Ss included 12 male squirrel monkeys approximately eight months of age. Experimental Ss, fed a riboflavin deficient diet, were tested on performance on a T-maze, a "vigor roller apparatus," and observed for digestive disturbances, general weakness, and loss of weight. Control Ss, fed a balanced diet, were given the same procedure. Significant results from the .001 to the .05 levels indicated experimental S s preferred a high riboflavin diet after the diet was deficient in this substance, and indicated digestive disturbances, lack of vigor, and loss of weight as compared with the control Ss.

Animals↗
PubMed2003

Effects of perinatal visual stimulation on preference, growth, and mortality in African clawed frogs (Xenopus Laevis).

Two exploratory experiments examined the effects of flashing light stimulation on growth, mortality, and behavioral preferences of Xenopus laevis tadpoles. Experiment 1 showed that tadpoles exposed to continuous visual stimulation, from egg-laying through postnatal day 40, had significantly higher mortality rates and weighed significantly less than controls. In contrast to controls, experimental tadpoles showed a preference for visual stimulation throughout early development. Results support the notion that augmented visual stimulation during early development affects species-typical development and the creation of postnatal preferences. Experiment 2 exposed subjects to propranolol in their water to investigate a potential sympathetic nervous system (SNS) mechanism responsible for the previous results. Tadpoles exposed to propranolol and visual stimulation simultaneously did not show a preference for the visual stimulation. Although this preliminary finding suggests SNS involvement, this notion deserves further investigation.

Adrenergic beta-Antagonists↗
PubMed1997

Stimulation of tachykinin NK-3 receptors in the nucleus basalis magnocellularis reduces alcohol intake in rats.

Injections in the nucleus basalis magnocellularis (NBM) of the tachykinin (TK) NK-3 receptor agonist [Asp5,6,MePhe8]substance P(5-11), also referred to as amino-senktide (NH2-SENK), markedly reduced alcohol intake in genetically selected alcohol-preferring rats, offered 10% ethanol 2 h/day. The threshold dose in the NBM was 0.5 ng/site, while neither 1 nor 10 ng/rat of NH2-SENK inhibited alcohol intake following administration into the lateral ventricle. Injection of NH2-SENK, 25 ng/site, in the NBM did not modify water or food intake in water deprived rats, providing evidence for the behavioral selectivity of the effect on ethanol intake. The selective TK NK-3 receptor antagonist, R-820, injected in the NBM at the dose of 1000 ng/site 5 min before NH2-SENK 5 ng/site, significantly reduced the effect of NH2-SENK. The selective TK NK-1 receptor agonist [Sar9,Met(O2)11]substance P inhibited alcohol intake following injection in the NBM only at 25 ng/site; but the same dose induced marked grooming and inhibited also water intake in water deprived rats. The present results confirm that TK NK-3, but not NK-1, receptor agonists selectively inhibit ethanol intake in alcohol-preferring rats and suggest that the NBM is a site of action for their effect.

Alcohol Drinking↗
PubMedDate not supplied

Age and gender differences in sexual behavior preferences: a follow-up report.

This study extends prior research on gender differences in sexual behavior preferences. The authors administered the 6-factors Inventory of Dyadic Heterosexual Preferences (IDHP)1 to 76 married or cohabiting couples (mean age = 35 years). Their preference patterns were compared to similar data obtained previously from younger (mean age = 21 years), single respondents. Gender differences that were replicated included women's stronger preferences for romantic foreplay and men's greater erotophilia and preferences for using erotica and combining alcohol and drug use with sex. Women's stronger conventionality was not replicated among older partners, both of whom were less conventional than their younger counterparts. Older men and women were also more inclined toward the use of erotica. Unlike younger men, older men were more negative toward the use of contraception. Implications for sexual safety, adjustment, communication, and therapy are discussed.

Adult↗
PubMed2006

Visual selective attention and the effects of monetary rewards.

Outcomes of actions, in the form of rewards and punishments, are known to shape behavior. For example, an action followed by reward will be more readily elicited on subsequent encounters with the same stimuli and context -- a phenomenon known as the law of effect. These consequences of rewards (and punishments) are important because they reinforce adaptive behaviors at the expense of competing ones, thus increasing fitness of the organism in its environment. However, it is unknown whether similar influences regulate covert mental processes, such as visual selective attention. Visual selective attention allows privileged processing of task-relevant information, while inhibiting distracting contextual elements. Using variable monetary rewards as arbitrary feedback on performance, we tested whether acts of attentional selection, and in particular the resulting aftereffects, can be modulated by their consequences. Results show that the efficacy of visual selective attention can be sensibly adjusted by external feedback. Specifically, although lingering inhibition of distractors is robust after highly rewarded selections, it is eliminated after poorly rewarded selections. This powerful feature of visual selective attention provides attentive processes with both flexibility and self-regulation properties.

Adult↗
PubMed2000

The cognitive bias task (CBT) in healthy controls: a replication study.

Contextual processing is the selection and bringing "on-line" of internal representations of a task that can be used in planning and mediating goal-appropriate behavioral responses and is a relevant issue that probably is involved in many neurological and psychiatric conditions. The Cognitive Bias Task is a measure of context-dependent responding, is sensitive to quadrant-lesion effects, and interacts with gender. The goal of this study was to replicate and detail more completely the method of context-dependent processing for healthy control patients on the Cognitive Bias Task. The results show the presence of three different cognitive patterns that could biases the response of control patients: context-independent, context-dependent, and mixed. Gender, but not handedness, significantly influences contextual processing, with more females than males producing a context-independent pattern of responding. Test results and the relation of contextual processing in psychiatric disorders were discussed.

Adult↗
PubMed2004

The relationship between antipsychotic treatment and quality of life for patients with dementia living in residential and nursing home care facilities.

For any treatment, the impact on quality of life (QoL) is a key consideration. These issues are particularly important in the pharmacologic management of behavioral and psychological symptoms in patients with dementia (BPSD). Although these symptoms can be very distressing for some patients, the overall relationship of the symptoms with QoL is far less clear. In addition, although antipsychotic agents have moderate efficacy in the short- to medium-term management of these symptoms, it cannot be assumed that symptom resolution automatically equates with improved QoL. This is of particular concern in light of the adverse side effect profiles of many of these agents. Indeed, the only empirical study in this area conducted to date indicated that antipsychotics are associated with a worse QoL for nursing home patients. Unfortunately, none of the placebo-controlled trials of antipsychotics for the treatment of BPSD have included formal QoL measures, although preliminary evidence indicates that atypical antipsychotics such as quetiapine may result in QoL improvements. The inclusion of systematic QoL measures in future clinical trials is imperative in order to provide evidence to enable the clinician to make informed judgments regarding the potential benefits or risks of pharmacologic treatment for individual patients. In addition, such information will facilitate a better understanding of the likely factors that may contribute to the impact of treatment on QoL (e.g., side effects) and hence enable physicians to make rational treatment choices between different pharmacologic agents.

Aged↗
PubMed2006

Directional preferences in turning behavior of girls and boys.

Turning biases in humans and animals are known to be related to dopaminergic asymmetry between the brain hemispheres. A laboratory method, in which turning preference was evaluated, was adapted based upon the turning of the subject toward a particular sound in a square room. One of the aims of this study was to investigate the reliability of this method with children, and the other aim was to research the turning preference in boys and girls. 31 children between 7 and 13 yr. old volunteered as subjects, and 17 subjects were retested. The subjects tended significantly to turn leftward (60.1%), and fewer girls (53.7%) turned to the left than boys (66.2%). The correlation between the test and the retest was significant (r=.79, p< .01). Most studies have indicated that humans in childhood and adulthood exhibit left-turning preference, but conflicts between the results obtained on different types of rotation tasks have suggested that hemispheric dopaminergic activity might affect preference. That needs study.

Acoustic Stimulation↗

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