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[A case of urachal abscess].

A 26-year-old male with urachal abscess was demonstrated. Ultrasonography, CT and MRI revealed that there was a mass at the supravesical region, which was connected to the umbilicus. However, a differential diagnosis as to whether the mass was a tumor or an abscess was difficult from these examinations. Thus we performed an open biopsy. A pathological examination revealed no malignant change in the biopsy specimen. On the other hand, the pathological diagnosis of a follicular tumor located at the roof of the urinary bladder was TCC G2, but we considered that, this change was a reactive hyperplasia with dysplasia resulting from chronic inflammation of urachal abscess. Thus, the complete excision of urachal abscess and partial cystectomy were performed. The serial sections of the bladder wall revealed no malignant changes. We reviewed similar cases reported in our country and discussed various factors causing urachal abscess, especially related to the infectious root.

Abscess↗

Intra-abdominal abscesses in Crohn's disease.

We reviewed 22 patients who had intra-abdominal abscesses secondary to Crohn's disease. A total of 29 abscesses were discovered. These included superficial and deep intraperitoneal as well as pelvic and retroperitoneal abscesses. Diagnosis was aided by ultrasound and computer tomographic scanning. Barium studies continue to play an important role in delineating the extent of bowel involvement and fistulization. Treatment varied depending on the location and size of the abscess. The need for ultimate bowel resection was determined in the majority of cases by the presence of fistulization between the abscess cavity and the bowel. The terminal ileum or neoterminal ileum were almost always involved.

Abdomen↗

[Etiology, diagnosis and treatment of hepatic abscesses after biliary tract surgery].

The majority of hepatic abscesses of biliary tract origin are the result of suppurative or non suppurative cholangitis, caused either by common duct stones, inflammatory stricture or malignancies. We report our experience of 7 consecutive liver abscesses after biliary tract surgery, treated in our surgical unit over a 2-year period, there were 6 females and 1 male with an age of 41 to 83 years. Hepatic abscess after biliary surgery developed from 10 days to 14 months postoperatively. Two patients underwent primary surgical drainage and remained clinically well 6 months and 2 years postoperatively. Five patients initially had percutaneous drainage and 4 of them subsequently underwent operative drainage; one patient declined any further operative treatment after percutaneous drainage and died 8 days later from continuing sepsis. Multiple factors may account for the development of both cholangitis and hepatic abscess following biliary tract procedures. Radiologic investigation should not only focus on the abscess itself but must also identify underlying biliary pathology. Our experience suggests that a surgical approach may be preferable to percutaneous techniques as it allows appropriate management of the associated biliary pathology.

Adult↗

Ampicillin-sulbactam therapy for multiple pyogenic hepatic abscesses.

A patient with multiple, pyogenic hepatic abscesses is described, and the pathophysiology, etiologies, clinical and laboratory manifestations, and management of the disease are reviewed. A 55-year-old man with a history of ethanol abuse and pancreatitis developed fever, chills, general malaise, and right upper quadrant abdominal pain two weeks before hospitalization. Baseline laboratory and hematology results included serum albumin concentration, 3.2 g/dL; serum alkaline phosphatase concentration, 239 mIU/mL; total serum bilirubin concentration, 1.3 mg/dL; white blood cell count, 18,400/cu mm; red blood cell count, 4.7 million/cu mm; hemoglobin, 12.5 g/dL; and hematocrit, 38.8%. Abdominal ultrasound showed echo-free cavities throughout the hepatic parenchyma; abdominal computed-tomography (CT) scan showed hepatomegaly and multiple radiolucent spaces. CT-guided needle aspiration of a hepatic mass yielded purulent material that grew Fusobacterium necrophorum under anaerobic conditions. On day 7, the patient was started on i.v. ampicillin sodium-sulbactam sodium. A CT scan two weeks later showed a reduction in the number and sizes of abscesses. The patient continued i.v. therapy for one month, then was discharged on a regimen of p.o. amoxicillin trihydrate-clavulanate potassium. Hepatic abscesses are either amebic or pyogenic; the latter usually has a higher mortality. The etiologies of pyogenic hepatic abscesses include ascending cholangitis, portal vein bacteremia, systemic bacteremia, extension from a contiguous focus of infection, and trauma. Diagnosis is difficult and relies highly on clinical suspicion. Clinical symptoms include hepatomegaly, fever, chills, and malaise. Abnormal laboratory values include leukocytosis, anemia, and hypoalbuminemia. The abscesses are frequently polymicrobial; Escherichia coli is the most commonly isolated species. CT is the best radiological technique for diagnosis.(ABSTRACT TRUNCATED AT 250 WORDS)

Ampicillin↗

Percutaneous catheter drainage of abdominal abscesses associated with perforated viscus.

Improvements in radiologic localization have made percutaneous catheter drainage (PCD) the initial procedure of choice for many intra-abdominal abscesses (IAA). During the past seven years 154 patients underwent PCD for treatment of abdominal abscesses. Fourteen of these patients had PCD as the initial treatment for IAA secondary to a perforated viscus and subsequently underwent an elective one-stage operation to treat the underlying disease. Etiologies of the abscesses included perforated appendicitis in six patients, sigmoid diverticulitis in three patients, Crohn's ileitis in two patients, and one case each of perforated gastric ulcer, perforated sigmoid carcinoma, and perforated gallbladder. Initial localization of the abscess was achieved by either CT or ultrasound. Seven abscesses were localized in the right lower quadrant, four were localized in the liver, and one was localized each in the left flank, right flank, subhepatic space, and pelvis. All patients subsequently underwent a definitive elective operation for their primary disease including six interval appendectomies, four sigmoid colectomies, two small-bowel resections, one subtotal gastrectomy and one cholecystectomy. There were no complications due to PCD and no deaths occurred. We conclude that PCD can be successfully performed as the initial treatment for IAA associated with a perforated viscus, obviating the first stage of the traditional two-stage surgical approach.

Abdomen↗

[Experience on the treatment of acute anorectal abscess with primary fistulotomy].

From August 1985 to July 1989, 72 cases with initial attacks of acute cryptoglandular anorectal abscesses were hospitalized and treated in Kuang Tien General Hospital. Among them were 52 cases of the perianal type, 8 of the intersphincteric type, 11 of the ischiorectal type and one case involving the supralevator space. Included were 62 males and 10 females (sex ratio 6:1) with a mean age of 39 years (range, 18 to 63). The mean duration of the follow-up was 24 months. Most anorectal abscesses originate from a cryptoglandular infection and are usually treated initially by incision and drainage. However, a fistula operation may be required if a fistula develops weeks or months later. Several published papers from various hospitals have also pointed out that this disease condition can be successfully treated by a one-stage operation-primary fistulotomy. In order to determine the source of infection, careful examination was carried out in the operating room under adequate anesthesia. A definite or at least a highly suspected offending crypt was found in 57 cases, all of whom were treated by primary fistulotomy. The remaining 15 cases whose offending crypts were undetectable, were treated by incision and drainage. Of the 57 cases treated with primary fistulotomy, four cases developed recurrent abscesses or fistulas. In the incision and drainage group, five cases developed recurrences. Among the nine cases of recurrence, five were of the ischiorectal type. The author surmises that acute anorectal abscess of the ischiorectal type was rarely cured by the one-stage primary fistulotomy operation. However, for the majority of perianal and intersphincteric abscesses, primary fistulotomy should be the first choice of management.

Abscess↗

[Multiple liver abscesses due to Candida albicans in a patient with acute promyelocytic leukemia: percutaneous transhepatic intraportal administration of amphotericin B].

A 36-year-old male with acute promyelocytic leukemia in second relapse was admitted to receive reinduction therapy in June, 1985, and entered into third complete remission, but he developed spiky fever after chemotherapy. Ultrasonic tomography revealed multiple liver abscesses and culture of the aspirates demonstrated Candida albicans in the abscesses. He was treated with intravenous administration of amphotericin B (AMPH-B) but the effect on the liver abscesses was unsatisfactory and consolidation therapy was difficult to start. AMPH-B (30 mg/day) was administered by percutaneous transhepatic intraportal administration (PTIA). About two months later, multiple liver abscesses disappeared. No remarkable complications such as severe fever, chill and renal dysfunction were recognized during PTIA of AMPH-B. So PTIA of AMPH-B is considered to be useful and safe for the management of fungal liver abscesses.

Adult↗

Nursing care of a patient with a subphrenic abscess.

A subphrenic abscess is an abscess which forms below the diaphragm and above the transverse colon. Patients in the postoperative period following gastric, esophageal or hepatic surgery are at risk of developing a subphrenic abscess especially if they are older, if they develop a leak at an anastomosis site or if there was a high operative blood loss. Nurses who are aware of high-risk patients should increase their observations of the signs and symptoms of early subphrenic abscess. Subphrenic abscesses are often managed on the general nursing units but signs of impending respiratory failure or circulatory collapse may warrant transfer of the patient to an intensive care unit. Nursing interventions are then focused on maintaining the body systems, evaluating the effects of the medical and nursing interventions and supporting the patient and family who may be very anxious at the severity of the unanticipated complication.

Humans↗

[A clinical assessment of the computed tomographic potentials in the diagnosis of postoperative peritoneal abscesses].

Modern diagnosis of postoperative abscesses in the peritoneal cavity keeps on being a difficult problem in abdominal surgery. They often develop against the background of the operation and the underlying disease, which masks the clinical course. Fourty-six patients suspected of having postoperative abscess were examined. Computer tomographic examination presented unequivocal data on the presence or absence of abscess in 42 patients (91.3 per cent), whereas in 6.5 per cent the conclusion was not emphatic for abscess and in 2.2 per cent there was lack of coincidence. This makes the method particularly suitable when other methods fail to produce explicit evidence for abscesses and the clinical suspicion remains.

Abscess↗

Ultrasonography as a diagnostic aid in horses with anaerobic bacterial pleuropneumonia and/or pulmonary abscessation: 27 cases (1984-1986).

The medical records of 83 horses with pleuropneumonia and/or pulmonary abscessation, in which thoracic sonography was used, were reviewed. The sonograms of these horses were reviewed retrospectively for free gas echoes within pleural or abscess fluid. Anaerobic infection was confirmed in 27 horses, and gas echoes were observed in 21 horses. There was a significant (P less than 0.001) correlation between the observation of gas echoes and anaerobic infection in horses with pleuropneumonia and/or pulmonary abscessation. A foul odor to the breath or pleural fluid was significantly (P less than 0.001) associated with anaerobic infection. Poor survival rates were associated with gas echoes or a foul odor to the breath or pleural fluid, both of which were associated with anaerobic infection. Gas echoes within pleural or abscess fluid were found to be a sensitive and specific indicator of anaerobic infection, as was a putrid odor to the breath or pleural fluid. Evaluation for gas echoes and foul odor had better predictive value than did evaluation for gas echoes or foul odor alone. Gas echoes within pleural or abscess fluid is highly suggestive of anaerobic infection. Ultrasonography should be performed repeatedly in horses with pleuropneumonia to assess the progression or resolution of pleural and parenchymal disease. The detection of gas echoes on subsequent ultrasonograms may indicate the development of anaerobic infection.

Animals↗

Bactericidal antimicrobial cover in primary suture of perianal or pilonidal abscess. A prospective, randomized, double-blind clinical trial.

The effect of 1-day treatment vs. 4-day treatment with metronidazole and ampicillin in association with primary closure of perianal and pilonidal abscesses was evaluated in a double-blind clinical trial. The patients were randomly allocated to 1-day (group I) or 4-day (group II) antibiotic regimen. No clinical signs of sepsis appeared in any patient. Primary healing, without fistula formation was achieved in all 17 perianal abscesses in the 1-day therapy group and in 14 of 15 in the 4-day group (non-significant difference). Excision with primary suture of pilonidal abscess resulted in primary healing in 20 of 26 cases in group I and 20 of 30 in group II (non-significant difference). Healing with formation of a new sinus or secondary healing occurred in four and two cases, respectively, in the 1-day therapy group, and in two and nine of the 4-day group. One-day administration of metronidazole/ampicillin is as effective as 4-day treatment in primary closure of perianal and pilonidal abscess. The procedure appears to be safe in both groups, but more efficacious in perianal abscess.

Abscess↗

[Surgery of cryptoglandular anorectal fistula and abscess. With special reference to complicated infections].

In an unselected personal consecutive series of anal fistulous abscesses (n = 253) 21 patients (8%) had a complex fistula, i.e. a translevatoric pelvirectal extension of an ischiorectal track (n = 7), a high intersphincteric fistulous abscess with an intramural or a pelvirectal extension (n = 7), a suprasphincteric fistula (n = 2), an intralevatoric fistulous abscess (n = 5). Treatment procedures were an ischiorectal laying open with translevatoric coring out, an intraluminal laying open into the lower rectum, and partial external sphincter division with seton drainage, respectively, as proposed in the literature. For the posterior levator space abscesses circular laying open into the anal canal lead to healing. In 2 patients with an anterior extension of an intralevatoric and with a suprasphincteric fistulous abscess, respectively, a posterior approach with a transsphincteric longitudinal excision of the diseased anosphincteric tissue was employed, with primary suture of the anorectum and of the sphincters, and with a covering colostomy. The procedure revealed to be useful with respect to exposure, fistula healing, and repair of previously transsected muscle.

Abscess↗

[Pancreatic abscess. Extraperitoneal drainage].

The pancreatic abscess occurs in two to six per cent of patients with acute pancreatitis and in 40 to 50 per cent of whom develop the severe form of the disease. The postoperative morbidity rate is 85 to 90 per cent and the mortality rate is 30 to 50 per cent due to persistence or recurrence of infection. The anatomical location and dissemination of the pancreatic abscess allows an extraperitoneal approach. Twelve patients with pancreatic abscess are reported. Seven males and five females, with an average age of 36 years. Fever, abdominal pain, cutaneous hypersensitivity and palpable abdominal mass were the most frequent clinical signs. Most of them developed multiple organic failure, leukocytosis, hyperglycemia, increasing L.D.H. and alkaline phosphatase levels. The CAT scan was most useful to localize the abscess. About 83 per cent of patients had been operated on previously. The extraperitoneal surgical approach was anterior in 10 patients and posterior in two patients. Ten patients developed complications that resolved with conservative measures. Two patients (17%) died. Extraperitoneal drainage is a valid alternative to prevent peritoneal contamination and some other serious postoperative complications in the management of pancreatic abscess.

Abscess↗

[Retroperitoneal perforation of duodenal ulcer responsible for abscess].

The authors report a case of retroperitoneal perforation of a duodenal ulcer. This is a rare condition which is exceptionally responsible for abscess formation. If often has a poor prognosis. In the present case, the abscess was infrahepatic. The diagnosis of the origin of the abscess was established by radiological opacification via percutaneous puncture. Surgical drainage and irrigation performed via an extraperitoneal approach centered over the cavity, combined with triple-agent antibiotic therapy (penicillin, gentamicin, metronidazole) ensured collapse followed by sterilisation of the abscess cavity. The ulcer was cured by medical treatment. This case differs from the published case in terms of the diagnostic procedures classically used (upper gastrointestinal endoscopy and small bowel series), the infrahepatic site of the abscess and the extraperitoneal surgical treatment which avoided dissemination to the peritoneal cavity.

Abscess↗

Brain abscess in cyanotic congenital heart disease.

Twenty-eight patients of cyanotic congenital heart disease (CHD) complicated with brain abscess were reviewed. There were 22 males and 6 females with a mean age of 9.1 +/- 5.5 years. Tetralogy of Fallot was the commonest cyanotic CHD observed. Transposition of great arteries (PS), tricuspid atresia with VSD, PS and double outlet right ventricle with VSD comprised 25% of the cardiac lesions. Febrile illness was the commonest mode of presentation (42.86%). Frontal lobe was the commonest site of abscess localization (37.5%) followed by parietal lobe (32.5%). Multiple abscess were seen in 32.14% and in 35.7% the pus was sterile on culture. Twelve patients died (mortality -42.8%), and autopsy reports were available in 6. Infective endocarditis was suspected in 7 on clinical grounds, while at autopsy, out of 6 only 2 had evidence of right-sided endocarditis. There was no correlation of mortality with age, sex, type of micro-organism, site of abscess localization and the nature of heart disease. Multiple abscesses, features of raised intracranial tension and associated meningitis/ventriculitis predicted a grim outcome.

Brain Abscess↗

Pancreatic abscess following acute pancreatitis.

Without surgical treatment, pancreatic abscess remains a highly lethal complication of acute pancreatitis. Many surgical series have reported mortality rates of 32 to 65 per cent in treated cases. Although pancreatic abscess is a rare condition, it is more common in patients with severe pancreatitis. A retrospective study of 130 patients admitted to our unit with severe acute pancreatitis during the period from 1965 to 1987 revealed 18 cases of pancreatic abscess. All pancreatic abscesses were primary in nature, and no infected pseudocysts were included in the series. Clinical surveillance, repeated laboratory tests, conventional radiology, and especially ultrasonography and CT scan all contributed to the preoperative diagnosis. The applied treatment was surgical debridement of all necrotic tissue and either local or extensive external drainage. In 12 cases this procedure was combined with other surgical interventions. The recorded mortality rate was 16.66 per cent. Factors adversely affecting survival include: 1) severity of precipitating pancreatitis; 2) difficulty in making early and accurate diagnosis of the pancreatic abscess; 3) marked tendency for recurrence of sepsis; and 4) life-threatening associated complications and/or diseases.

Abscess↗

[Specific features of rhino-sinusogenic brain abscesses in adults and children].

Analysis of observations of 49 patients with rhinosinusogenic brain abscesses revealed differences in their development between adults and children. This pathology occurs in adults more frequently than in children, particularly young children. In adults, brain abscesses usually develop as a result of chronic frontal- or polysinusitis, while in children they typically occur after maxillary sinusitis and in early age children also after acute suppuration in the nasal cavity. For adults, the contact pathway of infection is characteristic, whereas for children, the hematogenic-metastatic pathway is typical. Adults show single abscesses while children show both single, multiple and multichamber abscesses accompanied by separation of cranial sutures, thinning of calvaria, and protrusion and tension of the cranial fontanel. In children, abscesses may grow very large. In adults, the hypertensive syndrome is very distinct, while in children, the hydrocephalic-hypertensive syndrome comes to the foreground. In children, infectious-toxic symptoms are more significant. In adults, focal neurological symptoms become more serious than in children in whom they are also more labile.

Adolescent↗

[The subphrenic abscess. Surgical and/or percutaneous drainage].

The results indicate that the low risk percutaneous drainage of subphrenic abscesses is only feasible in carefully selected patients. The surgical intervention remains the method of choice for the drainage of subphrenic abscesses in conditions such as multiple and complicated abscesses, unfavourable access to the abscess cavities or other pathological conditions. An early and decisive diagnosis is crucial for effective treatment of subphrenic abscesses either by percutaneous drainage or surgical intervention and antibiotic therapy.

Adolescent↗

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