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[Analysis of mortality patterns in an area supplying tunnel workers away from home. Part 2. Mortality patterns among tunnel workers].

In order to clarify the long-term effect of tunnel work on the health of its workers, we examined its cause-specific mortality pattern. The subjects were 418 males who died after the age of 30 in 1977 in the southern part of Oita Prefecture, where many men come and work away from home as tunnel workers. Death certificates, 418 in number, presented to the health center were used to examine the causes of death. Occupational careers and life histories of the subjects were obtained by interviewing their families or relatives in 1980. The interviews were successfully carried out with 356 subjects (85.2%). The subjects were divided into two groups. One group was consisted of 73 males who had engaged in the tunnel work (tunnel workers) and the other was of 283 males without experience of tunnel work (others). Proportional mortality ratio (PMR) and proportional mortality classified by age were compared between the two groups. The mean ages at death were also compared among these two groups and all Japanese males over 30 years of age. The results were as follows. The proportion of the deaths of "tunnel workers" among the total deaths in the area surveyed was correlated to the regional rate of tunnel workers and the distribution of pneumoconiosis due to tunnel work. These results show that many tunnel workers suffering from pneumoconiosis had returned to their home area before they died. Excess deaths from the ICD category I; infective and parasitic diseases (000-136), tuberculosis (010-019) and silicotuberculosis (010) were found among the "tunnel workers."(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

Regeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formation.

Mitotic activity during regeneration in the planarian Dugesia (G) tigrina shows a biphasic pattern, with a first maximum at 4-12 h, a second and higher maximum at 2-4 days, and a relative minimum in between. The first peak is mainly due to pre-existing G2 cells entering mitosis shortly after cutting, whereas the second maximum is due to cells that divide after going through the S period from the onset of regeneration. From a spatial point of view, the highest mitotic values are found in stump (postblastema) regions near the wound (0-300 micron), though regions far from it also show increased mitotic values but always lower overall values. As regeneration continues the postblastema maximum shifts slightly to more proximal regions. In contrast, no mitosis has been found within the blastema, even though the number of blastema cells increases steadily during regeneration. The results suggest that blastema in planarians forms through an early accumulation of undifferentiated cells from the stump to the base of blastema. The results obtained demonstrate that blastema formation in planarians occurs through mechanisms somewhat different to those shown to occur in the classical epimorphic models of regeneration (Annelida, Insecta, Amphibia), and suggest that planarian regeneration could represent an intermediate stage between morphallactic and epimorphic modalities of regeneration.

Animals

Prevalence, group pattern, T pattern and seasonal variation of beta haemolytic streptococci in and around Shimla.

One hundred and seventy two strains of beta haemolytic streptococci were isolated from various clinical specimens over a period of one year. Group A was isolated in 69.70% and group C in 16.80 percent. Majority of the strains were isolated during winter season and only 21.00 percent in summer 93.30 percent strains were bacitracin sensitive and all were sensitive to penicillin. The most common T pattern among group A was found to be 5/11/12/27/44 followed by 3/13/B 3264.

Adolescent

Joint exercises in elderly persons with symptomatic osteoarthritis of the hip or knee. Performance patterns, medical support patterns, and the relationship between exercising and medical care.

A total of 110 community-living elderly persons with chronic hip and/or knee pain, all of whom met American College of Rheumatology classification criteria for osteoarthritis (OA), were interviewed to obtain information about their performance of therapeutic joint exercises and exercise-related medical care. Although exercises are considered standard treatment for OA and 96% of subjects had seen a physician for the problem, fewer than half had received medical advice to exercise and very few had received thorough exercise-related teaching and monitoring. Arthritis specialists provided significantly more support for exercising than primary care physicians. Forty percent of the total sample and 63% of those advised by a physician to exercise were making some attempt to do so; however, only 10% were exercising in a manner that might be expected to achieve maximum therapeutic benefit. Supportive medical care was highly related to frequency of exercising.

Aged