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At least 181 records · Page 10Linked to original sources
PubMed1985

The Kotz modular prosthesis in massive osteo-articular resections for bone tumours: preliminary results in 27 cases.

The authors report 27 cases in which neoplasms of the proximal or distal femur were treated by resection and replacement with a Kotz modular prosthesis. In 25 cases this was not cemented but in the other 2 cases cement had to be used. After describing the prosthesis and presenting the case material, the authors discuss the advantages and limitations of this surgical technique and compare the results obtained with those reported in the literature.

Adolescent↗
PubMed1988

Resection of the proximal humerus and I.O.R. modular prosthesis in the treatment of metastatic lesions.

The authors report a series of 20 patients affected with metastatic lesions of the proximal humerus (19 cases) or scapula (one case) treated by intra-or extra-articular resection of the humerus and successive reconstruction with an I.O.R. type shoulder modular prosthesis. This method is indicated for the treatment of patients with extensive destruction of the epiphysis and cortical bone and limited invasion of the surrounding soft tissues. Prosthetic implant does not contraindicate the use of postoperative radiotherapy, and the cement used to anchor the endomedullary shaft contributes to the sterilization of any metastatic microfoces present by means of an intense esothermic polymerization reaction. The results obtained were satisfactory, with regression of pain and good functional recovery of the limb. There were no postoperative complications.

Adult↗
PubMed1985

Modular hand tiller system for joystick operation of powered wheelchairs.

A method has been developed for assembling a hand support tiller that mounts to the post of a joystick controller of an electrically powered wheelchair. The hand tiller can be custom-designed by the therapist to fit the size, shape, and position of the user's hand. This results in a functional hand grasp that is necessary for the safe operation of the powered wheelchair. The design of the modular hand tiller system consists of low-cost, commercially available plastic tubing and fittings. This allows for an efficient set-up, easy modification, and durability.

Humans↗
PubMed1979

Marmor modular knee in unicompartmental disease. Minimum four-year follow-up.

Fifty-six consecutive knees were operated on for single compartment disease using the Marmor modular knee with a minimum follow-up of four years. The information obtained indicates that single compartment replacement is valuable in restoring function and relieving pain in a high percentage of patients. There was no evidence of late degeneration of the successful results at the time of writing. No difference in the results obtained with medial or lateral compartment replacement has been noted. Degeneration of the compartment not operated on has not been a problem. Unicompartmental replacement is an excellent procedure in the elderly patient who has osteoarthritis of the knee with varus or valgus deformity.

Aged↗
PubMed1979

A modular computer system for radiologists.

A computer system was developed for two private radiology offices, consisting of six modular components, a history file, registration file, assisted reporting module, appointment management module, accounting module and statistical module. Effectiveness and efficiency of patient care have been increased substantially.

Computers↗
PubMed1984

The Arizona program: development of a modular, interactive anesthesia delivery system.

Research by the Advanced Biotechnology Group, Department of Anesthesiology, the University of Arizona, has led to the development of many of the physical and theoretic elements necessary to the creation of a new automated anesthesia delivery system. Recognizing the obligation to provide means of the highest reliability and safety for anesthesia delivery, this group is endeavoring to bring together a compact, integrated modular system of the greatest utility to the practicing anesthesiologist.

Anesthesia, Inhalation↗
PubMed1984

[Modular organization of callosal neurons in the sensomotor area of the cerebral cortex in the rabbit].

The density of distribution of callosal neurons in rabbit sensorimotor cortex was studied by means of horseradish peroxidase injection into the homotopic cortical area. The irregularity of density was evaluated visually and/or computed. Labelled callosal units were mostly small and medium-size pyramidal cells located primarily in layer III-IV and more rarely in layers V and VI. Layer III-IV revealed different patterns of labelled units grouping: in pairs, in 5-8 vertically situated cells, in clusters 120-200 micron wide, separated by areas with decreased density. The obtained results confirm previously made conclusion based on electrophysiological studies about the modular organization of callosal connections in sensorimotor cortex of rabbits.

Animals↗
PubMed1983

[Modular system for the total replacement of the femur--Endo-model].

Total femur replacement may offer a useful solution in cases of severe trauma or neoplasia and in revision arthroplasty after failed total joint replacement when gross losses of bone have resulted in an unloadable femur and all other methods of treatment would fail to provide the patient with a stable leg. Until recently, total femur components were custom-made, but now we have a comprehensive modular total femur implant available reducing problems of preoperative preparation and simplifying the manufacture of custom-made designs. The new device can be shaped and adapted to the conditions encountered at the time of operation. The "push-through" type of prosthesis can be mounted step by step and converted into a total femur replacement with either a conventional head or a saddle at the proximal end and a total axial rotating knee prosthesis at the distal end. Elongation of the entire system is feasible.

Adult↗
PubMed1982

Clinical and radiographic evaluation of modular knee replacement. A review of 95 cases.

Ninety-five modular total knee replacements, 54 of them unicompartmental, have been reviewed. The average follow-up was three years. The major indication for operation was pain. A precise reoperative radiographic evaluation and a technique for a positioning the components are described. This had led to a significant improvement in the clinical and radiographic results in 67 out of 95 knees which were operated on. The modifications concern the orientation of the tibial cut, the placing of the femoral components and the correction of axial deviation. The main causes of the 13% of failures in our series were either errors in positioning the components or a preoperative diagnosis of rheumatoid arthritis. Unicompartmental replacement gave similar results in both valgus and varus knees, and the morbidity was lower than in the biocompartmental replacements. The best results were obtained in osteoarthritic knees in elderly patients and in posttraumatic osteoarthritis.

Adult↗
PubMedDate not supplied

Modular design of microcomputer-based medical instruments.

A modular design approach is effective for developing compact microcomputer-based medical instruments. Each instrument consists of two modules: a microcomputer instrument module that provides data conversion and computing functions and a characteristic module that does analog signal conditioning and includes all interfaces to the environment. The five instruments summarized here are: (a) a portable, battery-operated arrhythmia monitor for ambulatory patients; (b) a physician's computer for remote telephone communication with the portable monitor; (c) a battery-powered arrhythmia monitor/recorder for the operating room; (d) a portable, battery-operated biofeedback device for speech therapy; and (e) a neuromuscular blockade monitor for the operating room.

Computers↗
PubMed1993

A modular learning environment for protein modeling.

We propose in this paper a modular learning environment for protein modeling. In this system, the protein modeling problem is tackled in two successive phases. First, partial structural informations are determined via numerical learning techniques. Then, in the second phase, the multiple available informations are combined in pattern matching searches via dynamic programming. It is shown on real problems that various protein structure predictions can be improved in this way, such as secondary structure prediction, alignment of weakly homologous protein sequences or protein model evaluations.

Amino Acid Sequence↗
PubMed1979

Discrete modular system for automation of radioimmunoassay of serum choriomammotropin.

We describe a discrete automated radioimmunoassay system for determining choriomammotropin (placental lactogen) in human serum. With the present system it can be measured in as many as 37 unknown sera (50 muL) and three quality-control sera, in duplicate, within 1.5 h. The time required for sample preparation, incubation (15 min), and separation of free and bound radioactivities (a 150 mL/L polyethylene glycol solution is superior to a twofold volume of absolute ethanol) is less than 45 min. The remaining time required is for counting and data processing. Intra-assay precision is 4.6% (CV). The modular approach endows the instrumentation with much flexibility, and consequently is suitable for automation of a wide range of assay protocols.

Autoanalysis↗
PubMed1977

Urinalysis by modular learning.

A self-instructional approach to the entry-level presentation of urinalysis in a written modular format was used by a class of medical laboratory technician students. The course consisted of 13 modules based upon behavioral objectives. The modules used no audio or visual media but required "hands-on" performance of laboratory procedures. The achievements of a test sample of 12 students were compared with those of a previous class in which the same material was presented in lectures. Evaluation by written tests given to both classes showed no statistical difference. The self-instructed students performed adequately in their practical laboratory work, but the overall learning time was increased by 50 percent when self-pacing was used. A measurement questionnaire revealed that the students preferred instructor-led courses to self-instructional units for a variety of reasons which lead to some further considerations.

Attitude↗
PubMed1976

Modular total knee-replacement arthroplasty. A review of eighty-nine patients.

Fifty-eight osteoarthritic and thirty-one rheumatoid patients underwent modular total knee-replacement arthroplasty. The major indication for the operation was relief of pain. Contraindications to this resurfacing arthroplasty included varus-valgus instability of over 20 degrees, combined varus-valgus instability with flexion contracture of over 40 degrees, marked recurvatum, and predominant patellofemoral symptoms. In 59 per cent of the osteoarthritic and 58 per cent of the rheumatoid patients, complete relief of pain was evident when they were evaluated twenty-four months after surgery, while another 35 per cent of each group had only mild pain related to inclement weather. Their ability to walk long distances without support or limp was increased. Range of motion and ability to climb stairs were not significantly improved.

Aged↗
PubMed1976

The Modular (Marmor) knee: case report with a minimum follow-up of 2 years.

A follow-up of 2 years or more on 105 patients with the Modular (Marmor) knee replacement revealed that 88 per cent of the patients had a successful result. The complications and failures are analyzed in depth. Late loosening of the components was not observed except with the 6 mm tibial plateau. Pain relief was dramatic as well as improved function, stability and motion.

Adult↗
PubMed1981

Modular computer programs for flow cytometry and sorting: the LACEL system.

A computer-based data acquisition, display and processing system for flow cytometers has been developed. The Los Alamos Cell Analysis (LACEL) programs and electronic hardware provide the capability to acquire list mode or histogram data for up to eight parameters and control bidirectional sorting based on up to four parameters for each direction. The programs described in this paper also enable the display of single parameter and bivariate histograms and the graphical manipulation of the list mode data. The electronic hardware is described in a companion paper.

Cell Separation↗
PubMed1984

Modular structure of the beta-globin and the TK promoters.

Three regions important for transcription, the ATA box, the middle and the distal element, have been identified in the 5'-flanking region of both the rabbit beta-globin and herpes simplex virus thymidine kinase (TK) gene. To determine whether these elements are functionally equivalent, we constructed mosaic promoters containing all combinations of the three regions from both promoters and joined them to the beta-globin transcription unit. In an enhancer-dependent transient expression assay the beta-globin, the TK and all mosaic promoters retaining the beta-globin ATA box were about equally active, however, mosaic promoters with the TK ATA box were 4- to 10-fold less active. We conclude that homologous elements are, in principle, exchangeable and suggest an explanation why certain combinations of elements function poorly.

Animals↗