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At least 181 records · Page 10Linked to original sources
PubMed2006

[Evaluation of therapeutic effects of Chinese materia medica by tongue image analysis software 1.0 based on tongue colors].

OBJECTIVE: To evaluate the therapeutic effects of Chinese materia medica in treating patients with different syndromes by tongue image analysis software 1.0 based on tongue colors, and to discuss the feasibility of applying this computer science-based techniques into drug evaluation. METHODS: The tongue colors and the areas of tongue fur were examined and analyzed by the tongue image analysis software 1.0 in healthy persons and the patients with different syndromes before and after treatment. The parameters of tongue colors consisted of the followings: the hue (H), the lightness (L), the saturation (S), and the values of red (R), green (G) and blue (B). RESULTS: Obvious differences could be revealed in tongue color index between the healthy persons and the patients in five groups of different syndromes. There also existed some significant differences in those index between patients before and after treatment. CONCLUSION: The tongue image analysis software 1.0 based on tongue colors is helpful to evaluate the therapeutic effects of Chinese materia medica.

Adolescent↗
PubMed1998

[Relationship between lipometabolic disorder in stroke with TCM syndrome differentiation and typing].

OBJECTIVE: To analyse the relationship between lipometabolic disorder in stroke with TCM Syndrome Differentiation and Typing. METHODS: The serum lipid, lipoprotein and apo-lipoprotein level of TCM treated group (142 cases) and control group (100 cases) were determined. The patients were subdivided into three Type-groups according to TCM Syndrome Differentiation: Phlegm-Dampness Stagnation (PDS), Yin Deficiency with Yang Hyperactivity (YDYH) and Qi Deficiency with Blood Stasis (QDBS) group. RESULTS: The results showed that the level of TC, TG, HDL, LDL, apoA1, apoB and apoA1/apoB were significantly different in PDS and QDBS as compared with control group (P < 0.05, P < 0.01, respectively), while lipometabolic disorder of PDS was most serious in TCM Syndrome Differentiation of stroke. The level of TG, apoA1/apoB were significantly different in YDYH in comparing with control group (P < 0.05). While the level of TC, HDL, LDL and apoB were insignificantly different than those of control group (P > 0.05). CONCLUSIONS: This study showed that lipometabolic disorder of stroke were correlated with Syndrome Differentiation of TCM. Stroke with PDS and QSBS should give removing Phlegm-Dampness, dredging Meridian and removing blood stasis treatment besides routine treatment.

Adult↗
PubMed1999

[Immunoregulation of Youguiyin, Sijunzitang, Taohong Siwutang in treating patients with deficiency of kidney, spleen and blood stasis syndrome].

OBJECTIVE: To study the different immunoregulatory effects of Youguiyin, Sijunzitang, Taohong Siwutang to patients with deficiency of Kidney, Spleen and blood stasis Syndrome respectively. METHODS: The treated group, 40 patients in each with deficiency of Kidney, Spleen and blood stasis were treated with Youguiyin, Sijunzitang and Taohong Siwutang respectively. Three control groups (20 patients each) were established respectively. Peripheral venous level of complement C3, circulating immunocomplex (CIC), interleukin-2 (IL-2), interferon-gamma (IFN-gamma), lymphocyte transformation rate (LTR), the activity of natural killer (NK) cell, and the phagocytic function of neutrophil were measured before and after treatment. RESULTS: Sijunzitang could reduce the level of CIC (P < 0.01), raise the activity of NK cell and LRT (P < 0.01) of the patients with deficiency of Spleen syndrome; the same did the Youguiyin to that of patients with deficiency of Kidney syndrome. Also, Sijunzitang could increase the level of IL-2 in blood and the phagocytic function of neutrophil (P < 0.05); the Taohong Siwutang could lower the level of CIC to patients with blood stasis syndrome (P < 0.01), increase the activity of NK cells (P < 0.05). CONCLUSION: Youguiyin, Sijunzitang could enhance the immunoregulatory function of the patients with deficiency of Spleen and Kidney, particularly the cellular immune functions, in which the Sijunzitang effect is more complete and significant, while Taohong Siwutang eliminated the effect of CIC in blood better.

Adult↗
PubMed1999

[Clinical observation of side effects of Tripterygium preparation].

OBJECTIVE: To observe the side effects of Tripterygium preparation (TP) in the course of treatment. METHODS: Two hundred and seventy-one cases of patients with rheumatoid arthritis (RA) were treated using various TP to observe the occurrence of adverse reaction. RESULTS: The influence on reproductive system with TP extracted from the leaf ester tab were less than that from the root (TP tab and TP multiglycoside tab, TPMG). In group of TPMG the rate of side effect of 60 mg daily dosage was more than 30 mg daily (P < 0.01). The main influence on digestive tract and irregular menstruation was before age of 50 years and on renal function was after age of 50 years. Those adverse reactions mainly occur within first ten years in long therapy period. The side effects of TPMG produced in the Dampness-Heat type of RA were lower than Yin-Deficiency of Liver and Kidney type of RA (P < 0.05). CONCLUSION: TP ester tab is available for young woman and TPMG tab is suitable for the Dampness-Heat type of RA with lower dosis maintenance therapy.

Adult↗
PubMed1999

[Clinical and experimental study of yushen jiangtang tablet in treating non-insulin dependent diabetes mellitus].

OBJECTIVE: To evaluate the therapeutic effect and safety of Yushen Jiangtang Tablet (YSJTT) in treating non-insulin dependent diabetes mellitus (NIDDM) of Qi-Yin Deficiency Syndrome (QYD). METHODS: One hundred and one patients of NIDDM with QYD were treated with YSJTT and compared with 60 patients of the control group treated with Shenqi Jiangtang Tablet. The experimental study on pharmacologic effect and toxicity of YSJTT was also conducted. RESULTS: The total effective rate of the YSJTT group was 87.12% and the markedly effective rate 44.55%, while those of the control group were 70.00% and 18.33% respectively, comparison between the two groups showed that the effect of the YSJTT group was superior to that of the control group, P < 0.01. No acute or chronic toxic or side effect was found in animal experiment. Pharmacologic study showed that YSJTT had obvious effect in decreasing blood glucose and serum triglyceride levels in rats with alloxan induced diabetes. CONCLUSION: YSJTT is effective in treating NIDDM, and apparent toxic-side effect of it was not found.

Adult↗
PubMed2000

[Clinical observation on therapeutic effect of xinyikang oral liquid in treating 92 patients of viral myocarditis].

OBJECTIVE: To observe the clinical effect of Xinyikang Oral Liquid (XYK) in treating viral myocarditis patients of Qi-Yin Deficiency and Evil-Toxin Encroaching Heart Type. METHODS: Randomized controlled method was adopted, the 92 cases in the XYK group received XYK and 30 cases in the control group received Qidong Yixin oral liquid treatment for 4 weeks as a therapeutic course. Their symptoms, signs, white blood cell count (WBC), erythrocyte sedimentation rate (ESR), lactate, aspartate aminotransferase (AST) dehydrogenase (LDH), creatine phosphokinase (CPK), creatine phosphokinase isoenzyme (CPK-MB), electrocardiogram (ECG) and dynamic ECG changes before and after treatment were observed. RESULTS: The improvement on chest stuffiness, short breath, fatigue and spontaneous perspiration in the treatment group was better than those in the control group (P < 0.05) and XYK showed obvious improving effect on ESR, AST, LDH, CPK and CPK-MB (P < 0.01 or 0.05). There was no adverse reaction or side-toxic effects revealed in using XYK. CONCLUSION: XYK has significant therapeutic effect in treating viral myocarditis.

Adolescent↗
PubMed2001

[Comparative study on efficacy of qinggan granule and bushen granule in treating chronic hepatitis C].

OBJECTIVE: To evaluate the efficacy of Qinggan Granule (QGG) and Bushen Granule (BSG) in treating chronic hepatitis C (CHC) from blood donors clinically, biochemically and pathologically as well as to explore the therapeutical principle and methods of TCM. METHODS: Sixty-six patients with CHC were divided into three groups, the 36 patients in the QGG group treated with QGG, the 18 patients in the BSG group treated with BSG and the 12 patients in the control group untreated. The dose of QGG and BSG given was 30 g each time, three times per day for 6 consecutive months. Clinical and serum biochemical parameters as well as pathological change of liver biopsy before and after treatment were observed dynamically and compared. RESULTS: After treatment, in the two treated group, clinical symptoms were improved significantly, alanine transaminase (ALT) and aspartate aminotransferase (AST) reduced markedly. Moreover, QGG showed the effects of increasing albumin and lowering alkaline phosphatase (ALP). On the contrary, ALT still remained as before but AST further increased in the control group. Pathological examination showed that the inflammatory grade (IG) decreased in 42.2% and fibrotic stage (FS) decreased 21.2% of the patients in the QGG group, but no significant changes of the two indexes occurred in the BSG group, while in the control group, IG unchanged and FS increased in 3 cases. Chevallier's semi-quantity system analysis showed significant decrease of both scores in the QGG group (P < 0.05), only decrease of IG in the BSG group, and slight raise of IG and significant increase of FS (P < 0.05) in the control group. CONCLUSION: Condition of chronic hepatitis C patient would deteriorate progressively if not treated in time, especially the development of fibrosis. QGG and BSG could improve the clinical symptoms significantly, lower ALT and AST, eliminate inflammatory damage in the liver, slow down or reverse liver fibrosis process with stable long-term effect. Though most of the patients present a Syndrome of Liver-Kidney Yin-deficiency, the effect of QGG is superior to that of BSG, suggesting that the treatment of CHC should mainly be clearing principle, and method of clearing Liver and eliminating Dampness may be more suitable for them.

Adult↗
PubMed2001

[Preliminary study on relationship between TCM syndrome-type and insulin resistance in coronary heart disease].

OBJECTIVE: To observe the relationship between TCM Syndrome-type and insulin resistance (ISR) in coronary heart disease (CHD). METHODS: Fifty patients were divided into 3 groups according to the Syndrome Differentiation-typing in TCM, the Heart blood stasis (HBS) Syndrome group, the Phlegm-Turbid stagnation (PTS) Syndrome group and both Qi-Yin Deficiency (QYD) Syndrome group. The fasting blood glucose (FBG), fasting blood insulin (Ins), insulin antibody (IAA), islet cell antibody (ICA), glutamic acid decarboxylase antibody (GAD-Ab) and related blood lipid parameters in patients were determined and insulin sensitive index (ISI) was calculated simultaneously. Then the above-mentioned data were compared with those determined in 20 healthy control subjects. RESULTS: The levels of FBG and Ins in CHD group were higher than those in healthy control group significantly (P < 0.05), but ISI level was obviously lower (P < 0.01). Moreover, the positive ratio of IAA (40%) was higher in CHD group than that in the control group (5%) significantly (P < 0.01). Comparison between the 3 TCM Syndrome-type groups and the control group showed that ISI level in HBS and PTS group was obviously lower than that in the control and the QYD (P < 0.05) respectively, and the IAA positive ratio in the former 2 groups (50%, 47.3%) was higher than that in the later two (5%, P < 0.01 and 15.38%, P < 0.05) markedly. While Ins level increased only in the HBS group (P < 0.05). Besides, patients of HBS and PTS were accompanied by lipid metabolic disturbance. CONCLUSION: ISR presents in part of CHD patients particularly in those with HBS and PTS, which was partly due to the existence of IAA in patients serum.

Adult↗
PubMed2001

[Syndrome differentiation patterns for peri-operative coronary heart disease patients of coronary artery bypass graft].

OBJECTIVE: To explore the patterns of Syndrome Differentiation of coronary artery bypass graft (CABG) on the peri-operative coronary heart disease (CHD) patients. METHODS: One week after operation, thirty-seven CHD patients, who received CABG of internal mammary artery or great saphenous vein under conventional general anesthesia with low or middle temperature extracorporeal circulation were differentiated as various syndromes, the pre- and post-operational ECG, color Doppler echocardiography as well as during and after operation. The hemodynamic parameters were monitored. RESULTS: In the CHD patients, 64.9% were differentiated as Qi-Yin deficiency, 67.6% were complicated with Phlegm Syndrome and 62.2% with Stasis in blood, suggesting that Qi-deficiency, phlegm and stasis are the basic pathogenesis in patients after CABG. Moreover, the peri-operative Syndrome was correlated with the condition of coronary arterial lesions, heart and lung functions before operation, and the time for extracorporeal circulation during the operation. CONCLUSION: TCM Syndrome Differentiation conducting in peri-operative stage might be useful to explore the patterns of Syndrome alteration which provided a basis for preventing peri-operational complication and elevating success rate of operation.

Adult↗
PubMed2002

[Study on stroke syndrome of Chinese medicine and its relationship with blood hypercoagulative status and insulin resistance in diabetic ischemic stroke patients].

OBJECTIVE: To study the relationship of TCM Syndromes, involving Viscera Syndrome and involving Meridian Syndrome, with blood hypercoagulative state and insulin resistance in patients with diabetic ischemic stroke. METHODS: Insulin sensitivity index (ISI) could reflect the insulin resistance, and those reflecting blood hypercoagulative state parameters such as platelet agglutination test (PAgT), fibrinogen (FG), in vitro thrombus length (VTL) and activating partial thrombinogen time (APTT), were used to expound and prove the relationship with the stroke syndrome. RESULTS: The symptom scores, PAgT, VTL, FG levels in patients involved with Viscera Syndromes (including those of Wind Syndrome, Phlegm-Dampness Syndrome, Heat-Fire Syndrome and Yin-deficiency with Yang-excess Syndrome) were significantly higher than those in patients involved with Meridian Syndromes (P < 0.05 or P < 0.01), while the ISI level in the former was lower than that in the latter (P < 0.01). CONCLUSION: There is close relationship between blood hypercoagulative state, insulin resistance and TCM Stroke Syndromes in patients with diabetic ischemic stroke.

Aged↗
PubMed1992

[The influence of different acupuncture manipulations on the plethysmogram of the patient with kidney deficiency].

In order to prove the specific property between the tonifying manipulation (TM) and reducing manipulation (RM), and search further for the key in improving the effect of manipulation, the influence of to on two different manipulations. The plethysmogram in the same body-condition (kidney-deficiency) One was TM with slow-trusting and quick lefting; the other was RM with the converse movement. Randomized block design, cross-over design and single-blind design were used. The result showed that the TM increased the amplitude of the plethysmogram obviously, whereas the RM had no significant influence on it. There was significant difference not only between the TM group and the central group, but also between the TM group and RM group (P less than 0.01 or P less than 0.05). The difference between the RM group and the control group was not significant (P greater than 0.05). Meanwhile, it was recommended that "mind concentration" on acupuncture manipulation is important. In conclusion, the experiment demonstrated the experimental evidence for explaining the mechanism of TM and RM. It was suggested that acupuncture manipulations are worthy to pay attention so as to improve clinical effect.

Acupuncture Therapy↗