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Inadequate response to treatment in coronary heart disease : adverse effects of type D personality and younger age on 5-year prognosis and quality of life.

BACKGROUND: Improvement in treatment of patients with coronary heart disease (CHD) has caused longer survival but also an increase in the number of patients at risk for subsequent cardiac events and impaired quality of life (QOL). We hypothesized that chronic emotional distress confers an increased risk of poor outcome despite appropriate treatment. METHODS AND RESULTS: This prospective study examined the 5-year prognosis of 319 patients with CHD. Baseline assessment included symptoms of depression/anxiety and distressed personality type (type D-ie, high negative affectivity and social inhibition). The main end points were cardiac death or nonfatal myocardial infarction and impaired QOL. There were 22 cardiac events (16 nonfatal); they were related to left ventricular ejection fraction (LVEF) </=50%, poor exercise tolerance, age </=55 years, symptoms of depression, and type D personality. Multivariate analysis yielded LVEF </=50% (OR, 3.9; P=0.009), type D personality (OR, 8.9; P=0.0001), and age </=55 years (OR, 2.6; P=0.05) as independent predictors of cardiac events. Convergence of these risk factors predicted the absence of the expected therapeutic response that was observed in 10% of the patients. When 2 or 3 risk factors occurred together, the rate of poor outcome was 4-fold higher (P=0. 0001). Estimates of medical costs increased progressively with an increasing number of risk factors. Smoking, symptoms of depression, and type D personality were independent predictors of impaired QOL. CONCLUSIONS: Decreased LVEF, type D personality, and younger age increase the risk of cardiac events; convergence of these factors predicts nonresponse to treatment. Emotionally stressed and younger patients with CHD represent high-risk groups deserving of special study.

Adult↗

Accused murderers: five MMPI personality types.

A cluster analysis of the MMPIs of 110 men accused of capital and first-degree murder identified five profile types. When these types were compared on 24 sociological and behavioral variables, they differed on 16. Significant variables include family history, drug and alcohol use, events preceding the crime, and relationship between the accused and victim. Comparisons were made with several other systems of classifying murderers.

Adult↗

Personality type and clinical evaluations in an obstetrics/gynecology medical student clerkship.

OBJECTIVE: The purpose of this study was to determine whether the Myers-Briggs type inventory extraversion is associated with clinical evaluation ratings that students earn during their (obstetrics/gynecology) junior medical student clerkship. STUDY DESIGN: The Myers-Briggs type inventory was administered to medical students during their obstetrics/gynec clerkship. Bivariate correlations between clinical evaluations, National Board of Medical Examiners subject scores, and data from the Myers-Briggs type inventory extraversion scale were analyzed. RESULTS: Pearson product-moment correlation between clinical and National Board of Medical Examiners subject scores was not significant (r = .25; P = .05). The National Board of Medical Examiners did not show significant correlations with the Myers-Briggs type inventory extraversion data. The clinical evaluations showed a significant correlation (r = .35; P = .005) with Myers-Briggs type inventory extraversion. CONCLUSION: Results show that Myers-Briggs type inventory extraversion is correlated positively with clinical evaluations. The National Board of Medical Examiners subject examination and clinical evaluations were not correlated significantly. Findings question whether clinical evaluation data should be included in the obstetrics/gynecology medical student evaluation process.

Adult↗

Relationships between suicidal behavior and personality types.

This study examined the hypotheses that introversion in general and the introverted-intuitive-feeling-perceiving (INFP) type as measured by the Meyers-Briggs Type Indicator are related to suicidal ideation and behaviors. Analyses of data from 330 university students found four interactive suicidal behavior risk models: introverted-perceiving (IP) (females); introverted-sensing-feeling (ISF) (males); introverted-intuitive-perceiving (INP) (males); extraverted-intuitive-judging (ENJ) (males). Study findings were interpreted in terms of implications for risk assessment and intervention.

Adult↗

The relationship between personality type and style of alcohol use.

Two hundred fifty male, alcoholic VA inpatients were administered the Millon Clinical Multiaxial Inventory (MCMI) and the Alcohol Use Inventory (AUI). A cluster analysis, based on the scales of the MCMI, yielded three clusters: Cluster 1 was the smallest and was described by the least overall psychopathology. Cluster 2 had significant elevations on Antisocial, Narcissistic, Paranoid, Drug and Alcohol Abuse scales. Cluster 3 was the largest and had significant elevations on Avoidant, Schizoid, Dependent, Passive-Aggressive, Anxiety, Dysthymia, and Alcohol Abuse scales.

Adult↗

Inhibitory ease--a personality type?

Measures of reactive, transmarginal and internal inhibition, inhibitory strength, extraversion (E) and neuroticism (N) were obtained from a sample of 25 Ss. A Principal Components analysis of the data disclosed factors which were identified tentatively as extinctive/reactive inhibition, transmarginal inhibition, and appetitive and aversive inhibitory strength. N loaded the transmarginal inhibition factor, and I(Introversion) the appetitive inhibitory strength factor. It is suggested that the role of E in appetitive CR extinction may be a function of the extent to which inhibitory strength is involved in inhibitory dynamism.

Adult↗

Psychosexual aspects of the panic-fear personality types in asthma.

Numerous earlier studies have demonstrated the close relationship between MMPI Panic-Fear categories and various medical outcome measures in asthma. The present study relates MMPI Panic-Fear categories to psychosexual development. Specifically, High Panic-Fear patients demonstrate oral preoccupations, Low Panic-Fear patients demonstrate anal preoccupations, while Moderate Panic-Fear patients do not demonstrate pre-Oedipal preoccupations. Thus, MMPI Panic-Fear categories, useful in predicting medical outcome measures, have now been related to developmental levels, with the explanatory power of developmental concepts as well as their implications for psychological treatment.

Adolescent↗

The correlation between personality type and performance time while wearing a respirator.

Many studies have shown that individuals perform better if not wearing a respirator compared with wearing a respirator. This study examined the degree of performance reduction attributable to specific dominant character traits. The subjects performed on a treadmill at a constant speed and grade resulting in 80-85% VO(2)max. A modified M40 respirator was used to create three levels of inspiratory resistance: 2.8, 16.8, and 27.3 cmH(2)O*(sec/L). The 31 subjects were tested using a Myers-Briggs Type Indicator and State-Trait Anxiety Inventory. Multiple regressions and an ANOVA were used to test for correlation. When air intake is very constricted, the only multiple regression equation that was found to be statistically significant was sensing-intuition (how one takes in information) and thinking-feeling (how one makes a decision) vs. performance time for the highest value of inhalation resistance. A simple linear regression between trait anxiety level and performance time was not found to be statistically significant for the same highest value of inhalation resistance.

Adult↗

[D-dimer and plasminogen activator of the urokinase type: personal experiences with breast cancer].

Plasma values of d-dimer, a stable end product of plasmin-induced fibrinolysis, were ascertained in 128 female patients with mammary carcinoma. These patients demonstrated significantly increased d-dimers in comparison with the control group with benign mammary disease (p < 0.01). The sensitivity and specificity of d-dimer were slightly higher than those of the established tumour marker CA 15-3 and CEA. There was no correlation between d-dimers in the plasma and increased expression of urokinase plasminogen activator (UPA) in the tissue. Increased d-dimers in the plasma of female patients with mammary carcinoma reflect multi-factoral interactions between carcinoma growth and the haemostatic-fibrinolytic system, and may be used as tumour markers.

Adult↗

[New investigations on the melancholic type personality structure in migraine patients].

In an earlier published study [16, 17, 18], it was demonstrated that migraine sufferers have personality traits significantly more strongly associated with the typus melancholicus than healthy individuals and patients with other mental and physical illnesses. They display a fixation on tidiness which manifests itself in an excessive striving for quality and quantity in performance-oriented situations. The main features of their social relationships are excessive helpfulness combined with an exaggerated tendency towards guilt avoidance and symbiotic attachment to their own families. They do not differ from unipolar depressives in these respects. The major aim of the new study is to examine whether the concept of the typus melancholicus in relation to migraine sufferers as proposed in the first study is adaptable to explaining the personality characteristics of migraine sufferers ("typus migraenicus"). Age-matched samples of 42 female migraine sufferers, 40 female patients with unipolar depression, and 41 female control subjects took part in the new study. The test instruments used were von Zerssen's Munich Personality Test (MPT) and a questionnaire specially designed by the first author for assessing the typus migraenicus (German "Fragebogen zur Erfassung des Typus migraenicus," or FETM). The results obtained using univariate and multivariate analyses demonstrate a confirmation of the typus migraenicus concept, although to a less pronounced degree than the previous study. This can be seen as supporting evidence that, independently of the study sample and the investigators, migraine sufferers display with higher random frequency a personality profile very similar to the premorbid personality structure in unipolar depressives.

Adult↗

Evidence-based medicine, guidelines, personality types, relatives and absolutes.

There is an epidemic of guidelines but very little evidence-based information has been assembled to tell us exactly how guidelines are best implemented. Guidelines, although very valuable, are essentially a reductionistic attempt to simplify the complexities of medicine. Clinicians may appreciate that each guideline should be prefaced by a statement that 'what follows may not be applicable to all patients' but there seems little doubt that guideline adherence will be used to assess quality of care by those unfamiliar with the complexities.

Clinical Protocols↗

Body type, personality temperament and psychotherapeutic treatment of female adolescents.

In a previous study on emotionally disturbed male adolescents (Stewart, 1980), the subjects were somatotyped in accordance with Sheldon's theory, and the implications of psychotherapeutic treatment were discussed. This is an exploratory study of emotionally disturbed female adolescents in residential treatment at the Anneewakee Treatment Center which seeks to define the population and formulate tentative treatment implications from the results of somatotyping.

Adolescent↗