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Strength of knots in surgery in relation to type of knot, type of suture material and dimension of suture thread.

The 12 commonest types of suture material in dimensions 7/0, 5/0, 000, 0 and 2 (USP, 1965) were tested in 16 types of knot with regard to tensile strength of knot using the loop method. The results are given in tabular form as the strength of the loop for alltypes of knot tested, and as the mean knoe efficiency for certain groups of knots. The knot efficiencies are compared with regard to the different types of knot, the various types of suture material, and the different dimensions of thread using statistical methods including variance analysis. The strength of unknotted thread within a given dimension showed considerable variations for different suture materials: a given material could be more than twice as strong as the weakest material of the same dimension. With very few exceptions, the knot was the weakest point in a suture loop subjected to disrupting forces. The knot efficiency depended very largely on the type of knot and the strength of different types of knots varied from 3% to 99% of the corresponding unknotted thread. With the exception of two types of steel thread and both types of catgut, the efficiency was low for most simple crossed knots and for many simple parallel knots, and here considerable variations were recorded. Knot efficiency was clearly highest and showed least fluctuation with complex and particularly complex knots, and was closely similar for these. The dependency of knot efficiency on the type of suture material (mean for 16 knots) varied from 44% (polyethylene) to 90% (multifil steel). The variations in dependency on material were greatest with simple knots and with certain materials, and decreased with increasing knot complexity. The dependency of knot efficiency on the dimension of any particular suture material was apparently of much less importance than the type of knot and type of material.

Polymers↗

Flexor tendon suture: a description of two core suture techniques and the Silfverskiöld epitendinous suture.

Flexor tendon injuries are commonly treated by orthopedic, plastic, and hand surgeons. Bunnell referred to zone 2 injuries as being in "no-man's land," plagued by poor results after surgical repair. Over the last 30 years, a better understanding of the biology of flexor tendon injuries, advanced surgical techniques, and perhaps most important, improved rehabilitation protocols, have afforded consistently good to excellent results after surgical repair at all levels of injury. Complications such as restrictive adhesions, joint contracture, and repair rupture, although less frequent, can compromise functional recovery.

Journal Article↗

Sutured calf pericardium: influence of the type and angle of the suture on mechanical behavior.

Careful selection of the biological tissue to be used in cardiac bioprostheses and a thorough knowledge of its mechanical behavior, facilitating both the prediction of this behavior and the interactions between the tissue and the other materials employed, is the best approach to designing a durable implant. For this purpose, a study involving uniaxial tensile testing of calf pericardium was carried out. Two sets of three contiguous strips of tissue were obtained from each pericardial membrane, to perform a total of 144 trials. Two samples were sewn with one of four commercially available suture materials: Gore-Tex, nylon, Prolene and silk. In each set of three samples, the center strip remained intact and unsutured to serve as a control, while the left-hand strip was sutured at a 45 degrees angle with respect to the longitudinal axis and the right-hand strip was sewn at a 90 degrees angle. All the samples were tested until rupture. The results demonstrated a significant loss of mean load (p<0.01) in the sutured samples at rupture. The angle of the suture had no influence on these results, although the stress/strain curves showed that, as the tensile stress increased, the mechanical behaviors were less uniform. The rupture of the collagen fibers could explain this phenomenon. The pericardium sutured with Gore-Tex presented a greater strain, or deformation (elongation), at lower levels of stress, regardless of the angle of the suture. The tissue selection criteria, based on the use of paired samples, enabled a correct prediction of the mechanical behavior of the tissue, with excellent correlation coefficients (>0.98) and a high degree of homogeneity in the results.

Journal Article↗

Evaluation of 5 knots and 2 suture materials for arthroscopic rotator cuff repair: very strong sutures can still slip.

PURPOSE: To compare a standard suture material with a newer material using multiple arthroscopic knot configurations and to evaluate the biomechanical performance of a new sliding-locking knot compared with 4 surgical standards. TYPE OF STUDY: Controlled laboratory study. METHODS: Five knots were evaluated (Weston, Tennessee, Duncan, SMC, and the new San Diego knot) using 2 suture materials, No. 2 Ethibond (Ethicon, Somerville, NJ) or No. 2 Fiberwire (Arthrex, Naples, FL). Eight samples were tested for each knot-suture configuration. Samples were pretensioned to 10 N and then loaded from 10 to 45 N for 1,000 cycles. Intact knots were loaded to failure. RESULTS: Fiberwire had significantly higher load-to-failure (276 +/- 24 N) compared with Ethibond (111 +/- 13 N) (P < .001), although there was no significant difference as a function of knot configuration. Of the 40 Fiberwire knots, 3 failed by early slippage during cyclic loading and 8 slipped at very low tension during load-to-failure. None of the Ethibond knots and none of the San Diego knots failed by early slippage. CONCLUSIONS: Surface characteristics and suture construction affect the tendency for knot slippage. CLINICAL RELEVANCE: Surgeons should understand the impact of handling characteristics, frictional properties, and ultimate failure load when selecting suture materials and knots for arthroscopic repair.

Arthroscopy↗

A review of sutures and suturing techniques.

The ideal suture is strong, handles easily, and forms secure knots. It causes minimal tissue inflammation and does not promote infection. It stretches and accommodates wound edema. Although no single suture possesses all of these features, proper selection of sutures helps achieve better results in skin surgery. Proper suturing technique is essential for obtaining good cosmetic results and avoiding scarring and poor wound healing. Techniques that must be mastered include good eversion of skin edges, avoiding suture marks, maintaining uniform tensile strength along the skin edges, and precise approximation along skin edges.

Humans↗

Suture materials in contaminated wounds: a detailed comparison of a new suture with those currently in use.

The relationship between five different suture materials (expanded polytetrafluoroethylene (PTFE), polypropylene, polyglycolic acid, polydioxanone and polyglactin 910) and infection has been studied in 540 guinea-pig wounds contaminated with synergistic enteric organisms. The recently introduced expanded PTFE suture has been studied because, unlike the others, it has not previously been studied under these contaminated conditions. The incidence of wound infection in the control series was 26 per cent and all suture materials increased this figure significantly. The infection rate using expanded PTFE of 51 per cent was similar to all other sutures except polyglycolic acid, which produced an infection rate of 41 per cent. This difference was not statistically significant at the 5 per cent level. This confirms other studies including our own which show that the presence of most suture materials in contaminated wounds increases the incidence of infection. It further demonstrates that expanded PTFE is no different from other materials in this regard.

Animals↗

Absorbable iris suture. An experimental evaluation of polyglycolic acid suture.

Suturing of traumatic or surgical iris wounds has proved to be a safe and feasible microsurgical procedure. Various suture materials have been tried experimentally and clinically. If the human iris forms scar tissue the ideal suture would be an absorbable, inert, proteinfree material causing no uveal reaction. It was the purpose of this study to evaluate the ocular tissue reaction to nylon, virgin-silk and polyglycolic acid (Dexon) after suturing of an experimental iridomy in 24 rabbit eyes. The tissue response was studied by biomicroscopy, iris fluorescein colour angiography, and histology. Nylon did not disintegrate and caused virtually no inflammatory reaction. Silk showed fragmentation and complete absorption after four to six months with moderate tissue response. Polyglycolic acid gave rise to a marked uveal reaction and depolymerised from the fifth to the sixth week. There was no wound dehiscence of the iris scar and the pupillary function remained intact. It is concluded that the non-absorbable materials are superior to the currently available absorbable sutures in iris surgery.

Absorption↗

[Suture of fresh Achilles tendon rupture. Comparison of open with percutaneous suture technique].

INTRODUCTION: The open repair of the acute Achilles' tendon rupture reduces the incidence of rerupture compared with nonsurgical treatment; however, it yields more surgical complications. Early mobilization of the patients improves the postoperative outcome. Percutaneous suture techniques have a low incidence of rerupture and improve the conditions for early mobilization. METHODS: This study includes all patients (n = 97) with acute subcutaneous rupture of the Achilles' tendon with surgical treatment at the University of Heidelberg from 1992 to 1999. Open surgical repair and postoperative immobilization has been compared with a percutaneous suture technique and postoperative early mobilization. Altogether, 77 patients (80%) have been interviewed and 62 patients (65%) have undergone a clinical examination. RESULTS: There were local complications in 18% of the patients after open repair (n = 49) compared with 6% of the patients after percutaneous suture. In both groups there were two patients (4%) who sustained a rerupture. In the control group there were two patients with deep vein thrombosis (4%) and 1 lung embolism (2%). The clinical examination revealed no difference between open and percutaneous repair except for some disturbances in sensitivity of the sural nerve after percutaneous repair. The lower expenditure of therapy in percutaneous versus open sutures show the comparison of the hospitalization rates (29% versus 88%) and the rates of endotracheal anesthesia (53% versus 90%). CONCLUSION: Percutaneous suture technique for the repair of the Achilles' tendon is a simple and safe surgical procedure which allows early mobilization with a low rerupture rate. Thus this method should be performed as standard procedure for acute subcutaneous rupture of the Achilles' tendon.

Achilles Tendon↗

Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis.

Sutural growth depends on maintenance of a balance between proliferation of osteogenic stem cells and their differentiation to form new bone, so that the stem cell population is maintained until growth of the skull is complete. The identification of heterozygous mutations in FGFR1, -2 and -3 and TWIST as well as microdeletions of TWIST in human craniosynostosis syndromes has highlighted these genes as playing important roles in maintaining the suture as a growth centre. In contrast to Drosophila, a molecular relationship between human (or other vertebrate) TWIST and FGFR genes has not yet been established. TWIST mutations exert their effect via haploinsufficiency whereas FGFR mutations have a gain-of-function mechanism of action. To investigate the biological basis of FGFR signalling pathways in the developing calvarium we compared the expression patterns of Twist with those of Fgfr1, -2 and -3 in the fetal mouse coronal suture over the course of embryonic days 14-18, as the suture is initiated and matures. Our results show that: (1) Twist expression precedes that of Fgfr genes at the time of initiation of the coronal suture; (2) in contrast to Fgfr transcripts, which are localised within and around the developing bone domains, Twist is expressed by the midsutural mesenchyme cells. Twist expression domains show some overlap with those of Fgfr2, which is expressed in the most immature (proliferating) osteogenic tissue.

Animals↗

Biomechanical analysis of suture anchors and suture materials used for toggle pin stabilization of hip joint luxation in dogs.

OBJECTIVE: To compare in vitro mechanical properties of toggle pins and toggle rods used as suture anchors and of 3 suture materials (50-lb monofilament polybutester, No. 5 braided polyester, and 5-mm woven polyester) commonly used as prosthetic ligaments in the repair of hip joint luxation in dogs. SAMPLE POPULATION: Femoropelvic specimens from the cadavers of 18 dogs. PROCEDURE: Suture anchors were compared by use of pullout tests. Suture materials were compared by use of monotonic and cyclic tensile tests; cyclic tensile tests were performed with the suture placed over the edge of an aluminum bar to simulate the edge of the femoral bone tunnel. In vitro mechanical properties of the ligament of the femoral head were determined by use of monotonic tensile tests, using bone-ligament-bone cadaveric specimens. The in vitro mechanical properties of the acetabulum-ligament-femur complex and of this complex following rupture of the ligament and stabilization with a toggle rod and 5-mm woven polyester were determined by use of compression tests that simulated weight-bearing. RESULTS: Mechanical properties of the toggle rod were not significantly different from those of the toggle pin. Woven polyester had the longest fatigue life in cyclic testing. Hip joints stabilized with a toggle rod and woven polyester had less than half the strength in vitro of intact joints. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that a toggle rod or toggle pin can be used for stabilization of hip joint luxations in dogs. Of the materials tested, braided polyester had the best in vitro mechanical properties.

Animals↗

Hemostasis and cold knife cone biopsy: a prospective randomized trial comparing a suture versus non-suture technique.

Two methods of obtaining hemostasis after cold knife cone biopsy were compared in a prospective randomized trial involving 200 patients. One method relied primarily on hemostatic sutures, and the other involved the use of a styptic solution (Monsel's solution) and vaginal pack, thus avoiding the use of sutures altogether. The short- and long-term morbidity in these two groups were compared and 12-month follow-up was completed. The use of sutures did not reduce the incidence of primary hemorrhage. Secondary hemorrhage was twice as frequent in the suture group, although this trend did not quite reach statistical significance. During long-term follow-up, significantly more patients in the suture group developed menstrual symptoms, cervical stenosis, and unsatisfactory colposcopy, requiring further operative intervention as a result.

Adult↗

[A new technic of cutaneous suture. The SAFE technic (Suture, Assisted by adhesive Film, for Esthetic results)].

A new cutaneous suture technique is described. It is designed for tegumental closing of rectilinear incisions in nonseptic surgery. The technique involves intradermal overcasting with monofilament non-resorbable suture covered with a double adhesive film which reduces strain and provides a therapeutic pressure; after ablation of the first film, it is replaced with adhesive films continuously for 2 months. This technique provides the following advantages: rapidity of suture, simplification of postoperative care, improvement in patient comfort, major reduction in duration of the inflammatory cicatricial period, improvement in final aesthetic results, spectacular in the case of zones under high mechanical tension (arms and legs, scapular belt, etc.), reduction in total cost: suture + postoperative dressing. This technique has been studied for 1 1/2 years in more than 400 patients undergoing various procedures, both for immediate suture and for resuture of the trunk and extremities; postoperative cicatrization appears to be optimal from the standpoints of both the surgeon and the patient, and in our experience, there have been only two minor allergic reactions which did not compromise normal cicatrization. This technique is presented in detail, with a summary of indications and results.

Cicatrix↗

[Epiperineural nerve sutures and neurilemmatic sutures. Comparative clinical results about 109 cases (author's transl)].

During the last ten years, 109 medical cases of traumatic hand nerve lesions have been observed, implicating 78 big nerves (median 35, cubital 42, radial 1) and 37 little nerves (median 35, cubital 42, radial 1) and 37 little nerves (interosseous, collateral, digital). 81 "mixte" epiperineural sutures have been realized (according to a technical proceeding purposed by one of the authors since 1970, and practised with the only aid of a simple optical increase by dissection's magnifying-glasses) : In the same time, 38 neurilemmatic sutures have been seen at second hand and their clinical results noted. 64+ of the global results are very good or "good" concerning the "mixte" epiperineural sutures against 34% for the neurilemmatic sutures. To note : the best quality of the results for the median nerve as well for the primitive sutures, and unfavourable influence of the associated lesions.

Hand↗

Ectocranial suture closure: a revised method for the determination of skeletal age at death based on the lateral-anterior sutures.

A new method for estimation of age-at-death based on the degree of suture closure is presented. The method employs simple ectocranial scoring of specific sites on the external table. Composite scores for two groups of sutures, lateral-anterior and vault systems, which are used to provide estimates of age-at-death, have been developed from a sample of 236 crania from the Hamann-Todd Collection. A variety of tests show that the lateral-anterior sutures are superior to the sutures of the vault, that ectocranial is superior to endocranial observation, and that age estimates are independent of race and sex. It is concluded that suture closure can provide valuable estimates of age-at-death in both archaeological and forensic contexts when used in conjunction with other skeletal age indicators.

Adult↗

Modified cross-pin femoral fixation using long needles, polydioxanone suture, and traction suture for hamstring anterior cruciate ligament reconstruction.

The use of cross-pin femoral fixation in anterior cruciate ligament (ACL) reconstruction using semitendinosus and gracilis (ST/G) tendons has been shown to be biomechanically sound. As a result of some technical problems that we encountered, we modified the technique of the DePuy OrthoTech Xact ACL Graft Fixation System (DePuy, Warsaw, IN) using No. 2/0 polydioxanone suture (PDS) with long needles normally used for inside-out meniscal repair. In addition, a No. 5 Ethibond suture loop (Ethicon, Somerville, NJ) is used for traction of the ST/G graft up the femoral tunnel. Using a 2-suture loops technique, the traction suture loop offers a more effective in-line pull for the graft and it pulls the ST/G loops slightly higher than the alignment PDS. By so doing, it lessens the chance of kinking the alignment guidewire or even amputating the graft. Although not reported in literature, this type of graft complication is possible in other single-alignment suture or guidewire techniques.

Journal Article↗

[A new suture device for continuous sutures in the intestinal tract].

A new surgical sewing device for continuous sutures of gastrointestinal anastomoses with needle and suture material was used for the first time to construct a latero-lateral enterostomy (functional end-to-end anastomosis) in the small intestine of pigs. In ten animals the course was mainly uneventful during the observation period of 10 days. One animal developed a postoperative anastomotic leakage. In five cases adhesions between the anastomotic region and the small intestine were found on postmortem examination, but there was no evidence of any slight leakage. On the whole, the sewing device operated faultlessly. At present, clinical use seems possible for long sutures, which are time-consuming when sewn manually, but it is still premature. One major disadvantage of the device is its size, which restricts its application to extra-abdominal tasks. Nonetheless, the principle of a mechanical device for running sutures should be investigated further.

Anastomosis, Surgical↗

[Intracutaneous skin suture with a resorbable synthetic monofilament suture].

We report about our good experience with a monofile, synthetic, absorbable Polydioxanone thread used for skin suture in an intracutaneous technique, after we performed more than 1,500 sutures of 7 to 30 cm length in patients of any age. We consider the suture to be suitable for children to achieve a cosmetically fine scare without a subsequent necessity to pull out the thread. The breaking strength, the absorbtion rate and the loss of inflammatory reaction is so satisfactory that we could not see any disadvantage by using this absorbable, synthetic thread for skin closure. Especially there was no disturbance in wound healing. In contrast, because of the secure and undisturbed wound-edge adaptation a non-irritant, firm, and hairline-like scar could be achieved. The time to carry out the suture is no longer than for other techniques.

Dermatologic Surgical Procedures↗

Mechanical characteristics of cross-stitch epitenon suture in association with various two-strand core sutures: a biomechanical study using canine cadaver tendons.

The purpose of this study was to investigate the ultimate tensile strength and stiffness of the cross-stitch epitenon suture technique in association with three different two-strand core suture techniques (the modified Kessler, Tsuge, and two-strand Savage). Twenty-four canine cadaver flexor profundus tendons were lacerated and repaired by one of the following techniques: the cross-stitch (Group 1), the modified Kessler with cross-stitch (Group 2), the Tsuge with cross-stitch (Group 3), and the two-strand Savage with cross-stitch (Group 4). Ultimate strength was determined with a tensile testing machine and stiffness was recorded by a video dimension analyser system. The ultimate strength of Group 2 (5.704 kgf) was significantly greater than that of the other techniques, followed by Group 4 (4.608 kgf), Group 3 (3.568 kgf), and Group 1 (2.935 kgf). The stiffness of Group 2 (495.8 kgf/m) was significantly greater than that of the other techniques, followed by Group 4 (369.7 kgf/m), Group 3 (225.7 kgf/m), and Group 1 (200.1 kgf/m). These results may be helpful to surgeons in deciding which core suture technique to use in association with the cross-stitch epitenon suture.

Animals↗