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At least 181 records · Page 10Linked to original sources
PubMed1998

Bilateral recession of superior rectus muscles: its influence on A and V pattern strabismus.

PURPOSE: To determine whether bilateral superior rectus recession modifies A and V pattern strabismus. PATIENTS AND METHODS: Three patients with V patterns and eight patients with A patterns underwent bilateral superior rectus recession with neither oblique muscle surgery nor vertical displacement of the horizontal rectus muscles. Another three patients with A patterns underwent simultaneous superior oblique tenotomy and superior oblique recession. RESULTS: Two of the patients with V patterns demonstrated an increase in the V pattern after surgery; one was unchanged. Five of the patients with A patterns converted to V patterns after surgery. In the remaining three patients the pattern was eliminated. The three patients who underwent superior oblique tenotomy along with superior rectus recession had large shifts toward V pattern (mean shift, 40 delta). CONCLUSION: Bilateral superior rectus recession tends to increase V patterns and reduce A patterns. Superior rectus recession may be synergistic with superior oblique tenotomy in collapsing an A pattern.

Accommodation, Ocular↗
PubMed2023

Exploring the complex spectrum of dominance and recessiveness in genetic cardiomyopathies.

Discrete categorization of Mendelian disease genes into dominant and recessive models often oversimplifies their underlying genetic architecture. Cardiomyopathies (CMs) are genetic diseases with complex etiologies for which an increasing number of recessive associations have recently been proposed. Here, we comprehensively analyze all published evidence pertaining to biallelic variation associated with CM phenotypes to identify high-confidence recessive genes and explore the spectrum of monoallelic and biallelic variant effects in established recessive and dominant disease genes. We classify 18 genes with robust recessive association with CMs, largely characterized by dilated phenotypes, early disease onset and severe outcomes. Several of these genes have monoallelic association with disease outcomes and cardiac traits in the UK Biobank, including LMOD2 and ALPK3 with dilated and hypertrophic CM, respectively. Our data provide insights into the complex spectrum of dominance and recessiveness in genetic heart disease and demonstrate how such approaches enable the discovery of unexplored genetic associations.

Cardiovascular genetics↗
PubMed2003

Unilateral inferior oblique muscle myectomy and recession in the treatment of inferior oblique muscle overaction: a longitudinal study.

BACKGROUND: The comparable long-term outcomes of inferior oblique muscle myectomy and recession for the treatment of superior oblique underaction (in primary position and straight right and left gaze) have not been well documented in the literature. The purpose of this study was to compare longitudinally these two procedures in a similar, patient population with binocular single vision, when both operations were performed by the same surgeon, with a minimum follow-up period of 12 months. METHODS: A total of 24 patients who randomly underwent either a unilateral myectomy (at the temporal border of the inferior rectus muscle) or a standard recession for inferior oblique muscle overaction associated with long-standing superior oblique underaction were evaluated preoperatively at 2 weeks, 4 months, and 12 months postoperatively by the same orthoptist. RESULTS: A total of 23 patients met the study criteria, (12 myectomies and 11 recessions). All but one patient had demonstrable binocular single vision. The average preoperative hyperdeviation in contralateral gaze was 26.5 prism dioptres (Delta) in the myectomies and 20 Delta in the recessions. This was reduced at 12 months postoperatively to 1.75 Delta in the myectomies and to 3 Delta in the recessions. Both procedures were largely self-grading, so that the larger the preoperative hyperdeviation, the greater the effect of surgery. CONCLUSIONS: Single inferior oblique muscle-weakening procedures were effective in the vast majority of patients, even when the preoperative primary position hyperdeviation was 15 Delta or more. An improvement occurred in both groups immediately after surgery and in many throughout the follow-up period represented by a continuing drift towards orthotropia, but there was a recurrence of the hyperdeviation in some of the recession patients.

Adolescent↗
PubMed2000

Health hazards of unemployment--only a boom phenomenon? A study of young men and women during times of prosperity and times of recession.

BACKGROUND: It has been suggested that high unemployment rates in society may be less harmful to the health of people than low unemployment rates. Therefore, a study was carried out to compare, among young men and women, the relationship between health and long-term unemployment during periods of rapid economic growth 'boom' and economic recession. METHODS: Two study groups were chosen at age 21 y (5 y after compulsory schooling ended) from an industrial town in northern Sweden. The first group (number 1083) was chosen and surveyed in 1986 (under 'boom' conditions); the second (number 898) was chosen in 1994 (under economic recession conditions). The non-response rate was 2% for the boom group and 10% for the recession group. The main outcome measurements examined were somatic and psychological symptoms. RESULTS: Health criteria for general health among long-term unemployed young men and women did not differ between the group surveyed in boom conditions and the group surveyed in recession conditions. The only exception was for psychological symptoms, which scored lower among the men in the recession group. Individual unemployment had a high explanatory power for poor health, in particular, psychological ill health. CONCLUSIONS: When comparing periods of boom and recession there was no difference in somatic and psychological symptoms for those who were long-term unemployed. Thus, the trade cycle appeared to have had no impact on their health.

Adolescent↗
PubMed2001

Plague dynamics and population genetics of the desert locust: can turnover during recession maintain population genetic structure?

The desert locust (Schistocerca gregaria) undergoes crowding-induced phase transformation from solitary form to gregarious form. The transformations involves changes in behaviour, colour, development, morphometry, fecundity and endocrine physiology. Recession populations of the desert locust exist primarily in the solitary phase as small populations in patchy environments and are prone to extinction because of climatic events. Significant genetic differentiation among recession populations along the Red Sea coast of Eritrea was previously reported. It was hypothesized that despite the mixing effect of recurrent swarms, metapopulation dynamics could have produced genetic divergence among these highly scattered recession populations. A Monte Carlo simulation of the population dynamics of the desert locust in a metapopulation setting, with a realistic range of parameter values clearly demonstrated that this is possible. Population growth was represented by a discrete-time logistic equation. The duration of recessions and swarms was sampled from normal distributions whose means and standard deviations were varied based on reported estimates. An average recession duration of 10 +/- 3 generations and swarm periods half as long but almost twice as variable produced a partitioning of the total genetic variance most similar to that in the empirical study. In conventional metapopulation analysis, whether turnover leads to increased or reduced divergence is dependent on the number of colonists relative to the number of recurrent migrants, and on whether the colonists arise from a single patch or many patches. In the case of locusts, the stochastic boom and bust cycle is the overriding factor. Divergence between patches during recession due to founder effect and recurrent drift is balanced by the high rate of mixing during plagues.

Alleles↗
PubMed2001

Unilateral recession and resection in Duane syndrome.

PURPOSE: To assess the efficacy of lateral rectus resection with medial rectus recession in the affected eye of patients with Duane retraction syndrome (DRS) with esotropia and limited abduction, compared with bilateral medial rectus recessions. METHODS: The charts of 9 patients with DRS who underwent a recession-resection procedure and 10 patients with DRS who underwent bilateral medial rectus recessions were reviewed. Ocular ductions (graded from 0 = full duction to -4 = total deficit), severity of retraction, alignment, head position, and binocular single vision field (for study group only) were recorded before and after surgery. RESULTS: Before surgery, the study and control groups did not differ in mean primary position esotropia (16.9 and 18.8 PD, respectively), face turn (16.5 degrees and 15.0 degrees, respectively), average limitation of abduction (-3.9 and -3.7, respectively), or adduction (-0.1 and -0.3, respectively). After surgery, both groups had similar mean face turns (3.9 degrees and 1.0 degrees ), esotropia (3.3 PD and 1.0 PD), and abduction limitation in the affected eye (-2.4 and -2.6). However, mean adduction was significantly worse in the control group than in the study group (-1.5 vs -0.6, P = .02). Globe retraction improved in all control subjects. It worsened in 5 study subjects and did not improve in the other 4. In the study group, 1 patient required reoperation for undercorrection and another was overcorrected. CONCLUSION: Seven of 9 patients with DRS, selected on the basis of esotropia, limited abduction, and mild retraction, benefited from a recession-resection procedure. Abduction improved to the same degree as seen after bilateral medial rectus recessions, with less tendency to limit adduction.

Adolescent↗
PubMed2002

A new dose-response curve for bilateral medial rectus recessions for infantile esotropia.

PURPOSE: In 1982, Mims et al generated the first rigorous dose-response curve for bilateral medial rectus recessions for infantile esotropia (ET). Curve fitting calculations were hampered by substantial variability of surgical effect for the larger angles of ET, and an exponential curve was chosen for angles below 30 ET and a straight line for angles above 30 ET. In a continuing effort to improve the surgical success rate, a new series of results of 113 bilateral medial rectus recessions performed from 1990 to 1998 for infantile ET has been analyzed to produce a new dose-response curve and to study other potentially useful variables. METHODS: The amount of medial rectus recession performed in this series was the original dose-response curve from 1982, with conjunctival recessions performed for angles above 35 ET. RESULTS: The best curve that could be fitted to the effect versus millimeters of bilateral medial rectus recession was a single exponential curve. Other parameters explored with multivariate analysis, including head circumference, developmental delay, and intraoperative angles under anesthesia were not helpful in predicting effect of surgery at 6 weeks postoperative. A total of 87% were aligned at 6 months after surgery. Surgical failure at 6 months was more prevalent with larger preoperative angles (P =.0007) and with developmental delay (age when child first sat alone; P =.0078). CONCLUSION: Between 1982 and 1990, decreased variability of results of bilateral medial rectus recessions for larger angles of infantile ET enabled the generation of a single exponential dose-response curve for the entire range of angles of infantile ET.

Algorithms↗
PubMed2004

Trafficking defects of a novel autosomal recessive distal renal tubular acidosis mutant (S773P) of the human kidney anion exchanger (kAE1).

Autosomal dominant and recessive distal renal tubular acidosis (dRTA) can be caused by mutations in the anion exchanger 1 (AE1 or SLC4A1) gene, which encodes the erythroid chloride/bicarbonate anion exchanger membrane glycoprotein (eAE1) and a truncated kidney isoform (kAE1). The biosynthesis and trafficking of kAE1 containing a novel recessive missense dRTA mutation (kAE1 S773P) was studied in transiently transfected HEK-293 cells, expressing the mutant alone or in combination with wild-type kAE1 or another recessive mutant, kAE1 G701D. The kAE1 S773P mutant was expressed at a three times lower level than wild-type, had a 2-fold decrease in its half-life, and was targeted for degradation by the proteasome. It could not be detected at the plasma membrane in human embryonic kidney cells and showed predominant endoplasmic reticulum immunolocalization in both human embryonic kidney and LLC-PK1 cells. The oligosaccharide on a kAE1 S773P N-glycosylation mutant (N555) was not processed to the complex form indicating impaired exit from the endoplasmic reticulum. The kAE1 S773P mutant showed decreased binding to an inhibitor affinity resin and increased sensitivity to proteases, suggesting that it was not properly folded. The other recessive dRTA mutant, kAE1 G701D, also exhibited defective trafficking to the plasma membrane. The recessive kAE1 mutants formed dimers like wild-type AE1 and could hetero-oligomerize with wild-type kAE1 or with each other. Hetero-oligomers of wild-type kAE1 with recessive kAE1 S773P or G701D, in contrast to the dominant kAE1 R589H mutant, were delivered to the plasma membrane.

Acidosis, Renal Tubular↗
PubMed2002

Effect of inferior oblique recession in strabismus sursoadductorius.

UNLABELLED: The aim of this retrospective study was a quantitative analysis of the effect of graded inferior oblique recessions (8 mm, 10 mm or maximal) in strabismus sursoadductorius. METHOD: 234 patients (2-81 years of age) with unilateral strabismus sursoadductorius and stereopsis were operated between 1990 and 1999. Maximal recession (14.6 mm) included an anteroposition to the lateral aspect of the insertion of the inferior rectus. Before and three months after the operation, horizontal and vertical deviations (VD) were assessed by cover testing in five positions of gaze. In 121 patients, additional subjective quantitative assessment, including cyclodeviation measurement, was carried out with Harms' tangent screen. RESULTS: The mean effect of the operation on VD in 25 degrees adduction increased from 6 degrees with 8 mm recession to 10 degrees with maximal recession. It was related more to the amount of preoperative VD in adduction than to the amount of recession. One patient had a limitation of elevation with a hypotropia of >4 degrees, 7% needed further surgery because of undercorrection. DISCUSSION: Maximal recession of the inferior oblique muscle is a suitable procedure even in patients with marked strabismus sursoadductorius. The rate of functional undercorrection is low and there is no risk from general anesthesia or significant postoperative limitation of elevation.

Adolescent↗
PubMed2005

Effectiveness of aroma on work efficiency: lavender aroma during recesses prevents deterioration of work performance.

The present study investigated whether exposure to aromas during recess periods affects work performance. Subjects comprised 36 healthy male students (mean age, 24.2 +/- 2.2 years) who were randomly divided into three groups: (1) control group, not exposed to aroma during recesses; (2) jasmine group, exposed to jasmine aroma during recesses; and (3) lavender group, exposed to lavender aroma during recesses. All participants completed five work sessions performing a task requiring concentration on a computer monitor, with each session lasting 60 min. Recess periods of 30 min were provided between each session. To clarify the time at which work concentration was lowest, work performance for the control group was analyzed. Concentration was lowest in the afternoon period, where afternoon drowsiness is strongest. Comparison of the three groups for this time period indicated significantly higher concentration levels for the lavender group than for the control group. No such effect was noted for the jasmine group. Although lavender is a sedative-type aroma, use during recess periods after accumulation of fatigue seems to prevent deterioration of performance in subsequent work sessions.

Adult↗
PubMed2002

Effect of lumbar disc herniation on clinical symptoms in lateral recess syndrome.

This study investigated the differences in the clinical features of lateral recess syndrome attributable to the bony entrapment of the spinal nerve root under the superior articular facet, and lateral recess syndrome and associated lumbar disc herniation. Ninety patients with pure bony entrapment (47 men, 43 women) ranging in age from 19 to 83 years (mean age, 63 years) and 59 patients with lumbar disc herniation in the lateral recess (43 men, 16 women) 19 to 85 years of age (mean age, 49 years) were included in this study. All patients had L5 root radiculopathies and were treated surgically. Although the early symptoms of patients with lateral recess syndrome often were in the lower extremities, many of the patients with associated lumbar disc herniation had a transition initially experiencing low back pain and subsequently having lower extremity symptoms. Flexion and extension of the lumbar spine exacerbated symptoms, particularly in patients with lumbar disc herniation. The results of the current study show that the clinical presentation of lateral recess syndrome differs depending on the cause of the compression in the lateral recess.

Adult↗
PubMed2002

The axillary flap approach to the frontal recess.

OBJECTIVES: To evaluate the access to the frontal recess using the axillary flap approach by identifying the frontal ostium during endoscopic sinus surgery. STUDY DESIGN: Prospective review of 64 consecutive patients (118 sides) undergoing axillary flap exposure of the frontal recess between November 1998 and July 1999. METHODS: Demographic data, identification of the frontal ostium, findings at surgery, use of nasal packing, the presence of postoperative symptoms, revision surgery, and the endoscopic appearance of the frontal recess were collected. The operative technique is presented. RESULTS: The frontal sinus ostium was identified in 96% of patients (104 of the 118 sides). Eight sides had Kuhn type 3 cells that required removal for clearance of the frontal ostium. Eighty-two percent of sides (97 sides) had endoscopically healed sinuses without symptoms after an average follow-up of 15.4 months. Six sides had middle meatal adhesions requiring division under local anesthetic. One patient has required revision surgery. CONCLUSION: The axillary flap approach to the frontal recess provides excellent access to the frontal recess and allows clearance of cells in the recess with identification of the frontal ostium in the vast majority of cases.

Adult↗
PubMed2006

Children's physical activity during recess and outside of school.

The purpose of this study was to examine children's physical activity during recess and outside of school. Third-, fourth-, and fifth-grade students (N = 270; 121 boys, age = 9.5 +/- 0.9 years; 150 girls, age = 9.6 +/- 0.9 years) wore sealed pedometers during a 15-minute recess period and outside of school for 4 consecutive school days. A factorial analysis of variance (grade by gender) was used to examine differences among grades and between genders for the following variables: recess activity time (RAT), recess step counts (RSC), out-of-school activity time (OAT), and out-of-school step counts (OSC). For all outcome variables, there were no significant interactions between grade and gender and no significant main effect for grade. A significant main effect for gender (F(1,264)= 73.1, p < .001) indicated that boys accumulated more RSC and OSC than girls (1268 +/- 341 vs 914 +/- 261 and 7229 +/- 2877 vs 5808 +/- 2059, respectively) and more RAT and OAT than girls (11.7 +/- 2.4 vs 9.4 +/- 2.2 and 77.3 +/- 28 vs 67.4 +/- 21, respectively). Boys spent 78% and girls spent 63% of their recess time engaged in physical activity. Outside of school, girls spent 20% and boys spent 25% of their time engaged in physical activity. RAT comprised 14% and 16% of total discretionary activity time for girls and boys, respectively. Boys in this study are more active during discretionary time periods compared to girls. Study participants spent the majority of their recess time engaged in physical activity.

Analysis of Variance↗
PubMed1993

Post-traumatic angle recession glaucoma: a risk factor for bleb failure after trabeculectomy.

In order to determine if post-traumatic angle recession is a risk factor for failure of glaucoma filtering surgery independent of age or race, the surgical results of trabeculectomy performed in 35 consecutive patients with angle recession glaucoma were compared with those of 35 matched patients with primary open angle glaucoma. A postoperative intraocular pressure of < or = 21 mm Hg (with or without glaucoma medication) was found in 15 of the 35 (43%) patients with angle recession glaucoma compared with 26 of the 35 (74%) patients with primary open angle glaucoma. The long term success of trabeculectomy was significantly worse in angle recession glaucoma when the results were analysed using Kaplan-Meier survival curves. Bleb failure occurred a mean period of 3.1 (SD 1.2) months after trabeculectomy in angle recession glaucoma compared with 9.4 (5) months in primary open angle glaucoma (p < or = 0.001). The finding that posttraumatic angle recession is a risk factor for failure of trabeculectomy, supports the use of antimetabolite therapy to suppress fibrosis after trabeculectomy in these patients.

Adult↗
PubMed1985

Performance evaluation of recessed microcathodes: criteria for tissue PO2 measurement.

Measurement of local tissue PO2 using recessed microcathodes has again been criticized. Therefore, we reexamined electrode performance. Sharply beveled electrodes (3 micron external diameter) were fabricated with several tip recess lengths (4-10 micron), and some recesses were filled with hydrated polymer. In vitro, 2-mm agar (3%) sheets were equilibrated with solution of known PO2 (continuously flowing). Electrode currents at 100-micron intervals through the agar and of convected superfusion solution were compared. At the longest recess lumen length-to-diameter ratio of 10, minimum response midagar (1 mm) averaged 98%. Performance improved with the use of recess polymer and increased recess length. For in vivo studies, microcathodes (ratio approximately 10) were fluid calibrated, and PO2 was measured at 10-20 micron through canine femoral artery walls. PO2 distribution fit a model for radial diffusion with medial O2 consumption. After local cyanide application to the femoral wall, PO2 fit a model for radial diffusion without tissue O2 consumption. Carefully designed microcathodes and experiments measure accurate tissue PO2.

Agar↗
PubMed1978

Treatment of localized gingival recessions. Part II. Coronally repositioned flap with a free gingival graft.

Fourteen teeth with localized gingival recessions were treated using a coronally repositioned flap with a free gingival graft (Bernimoulin, 1973). The second step of the procedure was performed 1 month after the free gingival graft was done. Clinical measurements of the recession, sulcus depth and keratinized gingiva were taken preoperatively and at 30, 90 and 180 days after surgery. A mean reduction in the recession of 2.73 mm was obtained after 6 months, which was equivalent to a 64% decrease of the original recession. A significant increase in the width of the keratinized gingiva, averaging 3.27 mm, was found after 6 months. All results remained stable after 30 days postoperatively. The values for gingival recession, sulcus depth and width of keratinized gingiva on the teeth adjacent to the recessions remained unchanged, since they were undisturbed by the procedure.

Gingiva↗
PubMed1980

Gingival recession in the lower incisor region of 15-year-old subjects.

A sample of 1,003 children, aged 15 years, were examined for prevalence of gingival recession. It was found that 17% had pseudo gingival recession and 1% had true recession. The highest degree of association with local etiological factors was that between recession and the width of keratinized gingiva; frenal pull was the second most highly associated factor followed by tooth arch relationship and the least association existed between plaque and gingival recession. There was no association between calculus and recession.

Adolescent↗
PubMed1980

The lateral recess syndrome. A variant of spinal stenosis.

Sixteen patients with a surgically proven lateral recess stenosis were studied retrospectively. Lateral recess stenosis should be suspected in patients with disabling intermittent neurogenic claudications. The neurological examination is usually unremarkable. the diagnosis is assured when the lateral recess measures less than 2 mm in height. A lateral recess of 5 mm or more rules out the possibility of a lateral recess stenosis. Surgical decompression of the lateral recess requires removal of the horizontal portion of the superior articular facet.

Aged↗