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At least 181 records · Page 10Linked to original sources
PubMed1984

Choice for conditioned reinforcers in the signaled absence of primary reinforcement.

Pigeons responded in a multiple schedule in which concurrent schedules of brief-stimulus presentation alternated with a component in which food was available (concurrent-chains component). In the initial links of the concurrent-chains component subjects chose either of two stimuli each correlated with the terminal link of one chain. The terminal links involved either variable-interval 30-second or variable-interval 60-second schedules. In the brief-stimulus component subjects chose between 0.5-second presentations of the terminal-link stimuli from the concurrent-chains component. Responding was generally maintained in the brief-stimulus component in two subjects for more than 300 sessions, suggesting that brief stimuli were conditioned reinforcers. During the brief-stimulus component, in 17 of 21 cases for which a minimal number of responses occurred, choice proportions above 0.55 were obtained for the brief-stimulus presentations correlated with the higher rate of primary reinforcement in the concurrent-chains component. These results support the suggestion that choice in conventional concurrent-chains procedures is partially controlled by production of the terminal-link stimuli.

Journal Article↗
PubMed1964

REINFORCEMENT OF DRINKING BY RUNNING: EFFECT OF FIXED RATIO AND REINFORCEMENT TIME.

Rats were required to complete varying numbers of licks (FR), ranging from 10 to 300, in order to free an activity wheel for predetermined times (CT) ranging from 2 to 20 sec. The reinforcement of drinking by running was shown both by an increased frequency of licking, and by changes in length of the burst of licking relative to operant-level burst length. In log-log coordinates, instrumental licking tended to be a linear increasing function of FR for the range tested, a linear decreasing function of CT for the range tested. Pause time was implicated in both of the above relations, being a generally increasing function of both FR and CT.

Alcohol Drinking↗
PubMedDate not supplied

Treatment of automatically reinforced object mouthing with noncontingent reinforcement and response blocking: experimental analysis and social validation.

A brief functional analysis indicated the object mouthing of a young girl diagnosed with autism was maintained independent of social consequences. Separate and combined effects of response blocking and noncontingent reinforcement (with preferred stimuli) were then evaluated as treatments for object mouthing. Although both interventions were unsuccessful when implemented separately, combining them resulted in generalized reductions that were socially valid.

Autistic Disorder↗
PubMedDate not supplied

The effect of noncontingent sensory reinforcement, contingent sensory reinforcement, and response interruption on stereotypical and self-injurious behavior.

Three analyses were conducted to assess the effects of different consequent stimuli on the rate of stereotypical and self-injurious behavior performed by two individuals with severe developmental disabilities and dual sensory impairments. An analogue functional analysis documented an undifferentiated pattern of problem behavior across all conditions for Participant 1. Data for Participant 2 indicated an undifferentiated pattern with lower frequencies in the demand condition. Stimuli chosen to compete with the type of sensory stimulation produced by the stereotypy and self-injurious behavior were presented noncontingently during play conditions. Noncontingent presentation of the specially selected stimuli resulted in reductions in stereotypy and self-injurious behavior. Finally, contingent presentation of the same stimuli with and without response interruption was assessed in a demand context. Contingent presentation of the specially selected stimuli plus response interruption resulted in more suppression than contingent sensory stimulus presentation alone. Results are discussed as to competing and concurrent schedules of reinforcement.

Adult↗
PubMed1987

A neurobiological alternative to the perceptual reinforcement hypothesis of stereotyped behavior: a commentary on "Self-stimulatory behavior and perceptual reinforcement".

A perceptual reinforcement theory of stereotyped movements is advanced by Lovaas, Newsom, and Hickman (1987) in an effort to integrate a number of diverse observations about the origins and maintenance of this behavior. We, in turn, argue that the theory, as presented, is logically flawed and fails to take into account important biological findings and theory concerning pathological stereotyped acts. An alternative theory, derived primarily from neurological concepts, is briefly described.

Autistic Disorder↗
PubMed2005

The role of dopamine in reinforcement: changes in reinforcement sensitivity induced by D1-type, D2-type, and nonselective dopamine receptor agonists.

Dose-dependent changes in sensitivity to reinforcement were found when rats were treated with low, moderate, and high doses of the partial dopamine D1-type receptor agonist SKF38393 and with the nonselective dopamine agonist apomorphine, but did not change when rats were treated with similar doses of the selective dopamine D2-type receptor agonist quinpirole. Estimates of bias did not differ significantly across exposure to SKF38393 or quinpirole, but did change significantly at the high dose of apomorphine. Estimates of goodness of fit (r2) did not change significantly during quinpirole exposure. Poor goodness of fit was obtained for the high doses of SKF38393 and apomorphine. Decrements in absolute rates of responding were observed at the high dose of quinpirole and at the moderate and high doses of SKF38393 and apomorphine. Changes in r2 and absolute responding may be due to increases in stereotyped behavior during SKF38393 and apomorphine exposure that, in contrast to quinpirole, were distant from the response lever. The present data provide evidence that sensitivity to reward is affected more strongly by dopamine D1-like receptors rather than D2-like receptors, consistent with evidence from other studies investigating consummatory dopamine behavior and the tonic/phasic dopamine hypothesis.

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-ben↗
PubMed2004

In vitro and in vivo behavior of self-reinforced bioabsorbable polymer and self-reinforced bioabsorbable polymer/bioactive glass composites.

The aim of this study was to investigate the in vitro and in vivo properties and degradation of (1) self-reinforced (SR) lactide copolymer, P(L/DL)LA 70:30, and (2) SR composites of the same polylactide and bioactive glass 13-93. The following three polymer and polymer-bioactive glass samples were studied: SR-PLA70, SR-PLA70 + BaG15s, and SR-PLA70 + BaG20c. In vitro behavior was studied in a phosphate-buffered saline for 87 weeks at 37 degrees +/- 1 degrees C and a pH of 7.4 +/- 0.2. In vivo behavior was studied by implanting the rods in the dorsal subcutaneous tissue of rats (SR-PLA70 + BaG20c) or rabbits (SR-PLA70 and SR-PLA70 + BaG15s) for 48 weeks. The degradation of the specimens was evaluated by measuring the changes in mechanical properties, crystallinity and molecular weight of polymer, water absorption, weight loss, and structural changes. Results showed that the addition of bioactive glass filler modified the degradation kinetics and material morphology.

Absorbable Implants↗
PubMed2006

Reinforcement effect of adhesively luted fiber reinforced composite versus titanium posts.

OBJECTIVE: The aim of the present study was to investigate the influence of the rigidity of different post materials (titanium versus glass fiber reinforced composite [FRC]) on the fracture resistance of endodontically treated teeth (ETT). METHOD: Forty-eight caries-free maxillary central incisors were randomly assigned to six groups (n=8). After endodontic treatment, teeth of four groups were flattened 2mm above and two groups at the cemento-enamel junction (CEJ). As control, specimens of one group received neither composite build-up nor post, and teeth were left empty (E). In another group only a resin composite build-up was placed (C). In two groups, both titanium and FRC posts were inserted. One group with titanium (2/T) and FRC (2/FRC) post received a 2mm deep ferrule preparation. For one group with titanium (0/T) and FRC (0/FRC) post no ferrule design was provided. All-ceramic crowns were adhesively luted on all specimens. Specimens were exposed to thermomechanical loading and finally statically loaded until failure. RESULTS: The median fracture load values (min-max) were: E=317 (242-404); C=387 (335-475); 0/FRC=352 (0-440); 2/FRC=502 (326-561); 0/T=420 (0-548), 2/T=517 (416-653). Statistically significant differences were computed between E, C, 2/FRC, 0/T and 2/T; between C, 2/FRC and 2/T; between 0/FRC, 2/FRC and 2/T; between 0/T and 2/T regarding maximum fracture load. SIGNIFICANCE: Fracture resistance of ETT is not influenced by the rigidity of the post material. The combination of ferrule preparation and endodontic post results in higher load resistance after TML than any other build-up design.

Composite Resins↗
PubMed1978

Effects on choice of reinforcement delay and conditioned reinforcement.

Pigeons chose between fixed-interval schedules of different durations presented in the terminal links of concurrent-chains schedules. The pair of schedules was always in the ratio of 2:1, but the absolute duration of the fixed intervals varied. In one set of conditions, the different terminal-link schedules were associated with different keylight stimuli (cued conditions). In a second set of conditions, the different terminal-link schedules were associated with the same stimulus (uncued conditions). Results from the cued conditions replicated previous findings that preference for the shorter fixed-interval schedule increased with fixed-interval duration. Preferences in the uncued conditions were lower than in the corresponding cued conditions but also increased with fixed-interval length. In addition, the degree of control under the uncued conditions was correlated with the extent to which the schedule during the terminal link was discriminated immediately upon entry into the terminal link. The pattern of results in both conditions was inconsistent with the notion that choice behavior matches relative immediacy of reinforcement. Reanalysis of previous evidence for matching (Chung and Herrnstein, 1967) showed that matching in fact did not occur, as the preferences of their subjects for the shorter of two delays also increased with the absolute size of the delays.

Journal Article↗
PubMed1990

Fast electrotransfer of human serum proteins in their native state from polyacrylamide thin gradient gels reinforced by textiles to polyvinylidene difluoride membranes. Rapid electrotransfer from thin gradient gels reinforced by textiles.

A fast electroblotting technique of native molecules electrophoretically separated in thin (0.25 to 0.5 mm) gradient gels, onto a high capacity membrane of polyvinylidene difluoride is described. Omitting methanol during transfer, the equilibration step is avoided and the same buffer is used in electrophoresis and transfer. As the gel reinforced by fabric never swells nor shrinks, and as all the bands are blotted, the transfer matrix exactly reflects the protein pattern of the original gel. Autoradiography is enhanced and electroelution is homogeneous in all parts of the gels. Significant improvement is noticed in binding proteins of molecular weight from about 20 kDa to more than 700 kDa, as suggested by complete electroelution of all native serum components.

Blood Proteins↗