Topicalization effects in cued recall of technical prose.
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Cues↗
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Results for “Proactive Inhibition”
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Serial position and clustering effects in a chimpanzee's "free recall".
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Animals↗
Examining a processing tradeoff explanation of proactive interference.
Burns (1989) claims that proactive interference effects occur in paired-associate learning because of tradeoffs in relational and response-specific processing. Consistent with this claim, Burns demonstrated that free recall of critical-list responses is better in the interference condition than in the control condition. Burns's processing tradeoff explanation predicts that the occurrence of this reverse-interference effect should be positively correlated with the occurrence of traditional interference effects. We present several experiments whose results are inconsistent with this prediction. We hypothesize that the reverse-interference effect is a list-length effect. The results of a final experiment, contrasting the predictions of the list-length and processing tradeoff explanations, support the list-length explanation.
Adult↗
Proactive interference of a sequence of tones in a two-tone pitch comparison task.
Subjects compared pitches of a standard tone and a comparison tone separated by 1,300-3,000 msec and responded according to whether the comparison tone sounded higher or lower in pitch than the standard tone. Three interfering tones at 300-msec intervals were presented before each pair of tones. Their pitch range varied, being either below or above the pitch of the standard tone; in some of the trials, their pitches were identical to the pitch of the standard tone (no interference). The highest error rate in performance was found when the interfering tones and the comparison tone deviated in the same direction in pitch from the standard tone. In turn, their deviations in the opposite directions resulted in the lowest error rate. This effect was not found to be dependent on whether the interfering tones were randomly ordered or monotonically ordered, together with the standard tone, into melodically ascending/descending sequences. An intermediate error rate in performance was found when the interfering tones and the standard tone were identical. The results support earlier hypotheses, presented in the context of retroactive interference, by demonstrating proactive interference of a tone sequence at the level of representations of individual tones.
Acoustic Stimulation↗
Behavioral and neurophysiological correlates of episodic coding, proactive interference, and list length effects in a running span verbal working memory task.
Updating refers to (1) discarding items from, (2) repositioning items in, and (3) adding items to a running working memory span. Our behavioral and fMRI experiments varied three factors: trial length, proactive interference (PI), and group integrity. Group integrity reflected whether the grouping of items at the encoding stage was violated at discarding. Behavioral results were consistent with the idea that updating processes have a relatively short refractory period and may not fatigue, and they revealed that episodic information about group context is encoded automatically in working memory stimulus representations. The fMRI results did not show evidence that updating requirements in a task recruit executive control processes other than those supporting performance on nonupdating trials. They did reveal an item-accumulation effect, in which signal increased monotonically with the number of items presented during the trial, despite the insensitivity of behavioral measures to this factor. Behavioral and fMRI correlates of PI extended previous results and rejected an alternative explanation of PI effects in working memory.
Adult↗
The neural bases of the effects of item-nonspecific proactive interference in working memory.
We reanalyzed the behavioral and fMRI data from seven previously published studies of working memory in order to assess the behavioral and neural effects of item-nonspecific proactive interference (PI; attributable to the accrual of antecedent information independent of the repetition of particular items). We hypothesized that item-nonspecific PI, implicated in age-related declines in working memory performance, is mediated by the same mechanism(s) that mediate item-specific PI (occurring when an invalid memory probe matches a memorandum from the previous trial). Reaction time increased across trials as a function of position within the block, a trend that reversed across the duration of each multiblock experiment. The fMRI analyses revealed sensitivity to item-nonspecific PI during the probe epoch in the left anterior inferior frontal gyrus and the left dorsolateral prefrontal cortex(PFC). They also revealed a negative trend, across trials, in the transient probe-evoked component of the global signal. A common PFC-based mechanism may mediate many forms of PI.
Adult↗
Auditory list memory and interference processes in monkeys.
Memory of 2 rhesus monkeys (Macaca mulatta) was tested in a serial probe recognition task with lists of 4 natural or environmental sounds, different retention intervals, and different manipulations of interference. At short retention intervals, increasing the separation of list items reduced the primacy effect and produced a recency effect. Similar results were shown by increasing interference across lists through item repetitions or making the first 2 list items high-interference items. These results indicated that decreasing first-item performance reduced proactive interference on memory of the last list items. At long (20 s) retention intervals, making the last list items of high interference reduced the recency effect, reduced retroactive interference, and produced a primacy effect. Taken together, interference plays a role in determining the primacy and recency effects of the serial-position function.
Animals↗
Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats.
Previous electrophysiological studies and computational modeling suggest the hypothesis that cholinergic neuromodulation may reduce olfactory associative interference during learning (M. E. Hasselmo, B. P. Anderson, & J. M. Bower, 1992; M. E. Hasselmo & J. M. Bower, 1993). These results provide behavioral evidence supporting this hypothesis. A simultaneous discrimination task required learning a baseline odor pair (A+B-) and then, under the influence of scopolamine, a novel odor pair (A-C+) with an overlapping component (A) versus a novel odor pair (D+E-) with no overlapping component. As predicted by the model, rats that received scopolamine (0.50 and 0.25 mg/kg) were more impaired at acquiring overlapping than nonoverlapping odor pairs relative to their performance under normal saline or methylscopolamine. These results support the prediction that the physiological effects of acetylcholine can reduce interference between stored odor memories during associative learning.
Animals↗
Contribution of the cholinergic basal forebrain to proactive interference from stored odor memories during associative learning in rats.
E. De Rosa and M. E. Hasselmo (2000) demonstrated that 0.25 mg/kg scopolamine (SCOP) selectively increased proactive interference (PI) from stored odor memories during learning. In the present study, rats with bilateral cholinergic lesions limited to the horizontal limb of the diagonal band of Broca, made with 192 IgG-saporin, were not impaired in acquiring the same olfactory discrimination task relative to control rats. Rats with bilateral 192 IgG-saporin lesions to all basal forebrain cholinergic nuclei (BF) also showed no impairment in acquisition of this task. However, the BF-saporin rats were hypersensitive to oxotremorine-induced hypothermia and demonstrated an increased sensitivity to PI following a low dose of SCOP (0.125 mg/kg) relative to control rats. The results suggest that weaker cholinergic modulation after cholinergic BF lesions makes the system more sensitive to PI during blockade of the remaining cholinergic elements.
Animals↗
Effects of sleep deprivation on short-term recognition memory.
A probe-recognition short-term memory paradigm was used to inquire into the precise effects of sleep deprivation on human memory. It was found that recognition performance, as measured by d', was generally impaired for each subjects after 24 hr of sleep deprivation. While d' was shown to decrease exponentially as the number of items intervening between the target and the probe increased, this decay rate was not affected by sleep loss. In addition there was confirmation of a previously observed increase in the positive skewness of reaction times after wakefulness. The data were consistent with the hypothesis that sleep deprivation increases the occurrence of lapses, periods of lowered reactive capacity, which prevent the encoding of items in short-term memory.
Adult↗
Proactive interference, retroactive interference--what about self-interference? A new interpretation of the recency-primacy shift.
The recency-primacy shift (RPS) indicates that memory for early list items improves and memory for later items becomes worse as the retention interval between study and test increases. In this contribution, this puzzling experimental finding--memory improving with time--is found to be consistent with a model in which recognition is temporarily interfered with by its own storage process (self-interference). I show that this interpretation can qualitatively better account for the RPS experimental data than can the dimensional distinctiveness model, the only other outstanding explanation of the RPS. Two experimental predictions separate the 2 models: The dimensional distinctiveness model predicts no RPS for 2-item lists, in contrast to self-interference, and as the overall timescale is changed, the dimensional distinctiveness model predicts no difference in the RPS whereas self-interference predicts significant changes.
Humans↗
Retrieval variability: sources and consequences.
A memory model that differentiates between active traces (ongoing electrochemical neural transmission) and passive traces (chemical/structural modification of neurons) is briefly outlined. Evidence suggests that new information is initially encoded as a passive representation within a fraction of a second, leaving little opportunity for retroactive interference with storage processes. Instead, it appears that retroactive interference results from disruption of post-acquisition processing which is necessary for subsequent retrieval. Using this hybrid cognitive-physiological framework, we examine possible sources of associative performance deficits. A distinction is made between similarity interference (arising from the content similarity of the target and interfering traces) and processing interference (arising from the competition between the two traces for use of a limited capacity processor). Both types of interference can act proactively or retroactively, and the similarity-processing and proactive-retroactive dimensions are viewed as orthogonal to the question of whether information is permanently lost or merely subject to a reversible retrieval failure. When reminder techniques (pretest cuing) are used, numerous instances of memory failure commonly identified as "acquisition failures" are found to be reversible without the occurrence of relevant new learning. This literature review constitutes the greater part of the paper. It is concluded that many memory failures are due at least in part to retrieval failure. Consideration of potential retrieval processes in light of the studies that are reviewed argues for the expansion of the initial active-passive trace distinction to three types of traces. In addition to active traces, these include two distinct types of passive traces, i.e., a small content-addressable reference catalog with innately defined dimensions that is used to locate more detailed passive traces, and a large capacity store of detailed passive traces that is location-addressable. The latter type of passive trace presumably is laid down almost instantaneously as events occur, i.e., in real time, whereas the reference catalog type of passive trace, which is used to address the detailed traces, is established somewhat after the sequence of events is complete. Hence, the reference catalog trace is more vulnerable and results in retrieval failure when it is disrupted.(ABSTRACT TRUNCATED AT 400 WORDS)
Amnesia↗
Memory and induced ECT convulsions.
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Auditory Perception↗
[Dynamics of the intellectual work capacity of hypertension patients during treatment in the biotron].
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Adult↗
The Wernicke-Korsakoff syndrome: a review of psychological, neuropathological and etiological factors.
During the past 10 years numerous investigations concerned with the neuropsychological, neuropathological and etiological factors involved in alcoholic Korsakoff's syndrome have been published. The neuropsychological research has focused on the patients' anterograde and retrograde amnesias, and several theories based upon current models of human information processing have been advanced as partial explanations of the amnesic syndrome. While neuropathological investigations have continued to implicate midline diencephalic structures in the chronic symptoms of this disorder, some very recent studies have begun to assess the role of neurotransmitters in the patients' memory disorders. The etiology of the disorder also appears to be more complex than once believed. Animal studies demonstrating the neurotoxicity of alcohol have suggested that the patients' severe memory deficits may be due to an interaction of malnutrition and the toxic effects of alcohol. Behavioral investigations reporting that non-Korsakoff alcoholics have memory deficits qualitatively similar to those of Korsakoff patients support the idea that Korsakoff's syndrome is not acute but may develop slowly during decades of alcohol abuse.
Adult↗
Cross-motivational effects of inescapable shock are associative in nature.
Exposure to inescapable shock interferes with the subsequent acquisition of an appetitive operant. This deficit may be due to either associative interference or activity reduction from the inescapable shock pretreatment. The relative importance of these two factors was examined by using an appetitive response choice discrimination procedure and concurrently measuring activity. Experiment 1 demonstrated separate associative and activity effects of inescapable shock, in that the animals exposed to inescapable shock made more incorrect responses than controls and were lower in activity. Experiment 2 demonstrated that these effects resulted from the uncontrollability of the shock, not from shock exposure per se. In Experiment 3, residual effects of inescapable shock were investigated by exposing animals to discrimination reversals. On these tests, inescapably shocked animals showed performance inferior to nonshocked controls, a result indicating that the effects of inescapable shock are not completely reversed by experience with contingent reward in the discrimination task. No evidence of an activity deficit was observed during this discrimination reversal. These results strongly suggest that associative factors play a more important role than activity reduction in mediating the effects of inescapable shock, at least when these are measured in an appetitive context.
Animals↗
Cognitive profiles in reading disability.
A group of 35 reading disable (RD) boys and 35 matched controls were studied over a two-year period in order to evaluate the validity of traditional hypotheses about the cause of serious reading impairment in preadolescent boys for whom the common disadvantages of economic privation, bilingualism, and emotional instability were absent. The popular hypothesis of perceptual deficit was not supported by the data, although the finding that most RD boys have a short-term memory deficit was affirmed. The most important new finding was that about one-fourth of the RD boys had serious difficulty in maintaining an efficient set to process and/or evaluate information, especially when that information was contained in oral speech.
Child↗
Serial probe recognition performance by a rhesus monkey and a human with 10- and 20-item lists.
A rhesus monkey performed at high accuracy in a serial probe recognition task with color pictures as stimuli. The monkey's serial position curve was similar in form to a human's and demonstrated the theoretically important primacy and recency effects with lists containing as many as 10 or 20 items. The high accuracy of the monkey was shown to be largely due to the minimization of proactive interference through the use of more than 200 distinct items. These results encourage the view of similar mechanisms of memory in monkey and humans.
Animals↗