SEARCH · Search PubMed
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
I report a patient with placental chorioangioma producing third trimester polyhydramnios. The ultrasonographic diagnosis and the complications of this tumor are discussed.
Seven twin pregnancies with concurrent polyhydramnios and oligohydramnios resulted in a perinatal mortality rate of 71%. The occurrence of this complication before 26 weeks' gestational age resulted in deaths of all fetuses, despite a variety of attempted therapies.
Two patients with acute renal failure in pregnancies complicated by polyhydramnios and multiple gestations are discussed. An acute increase in the size of the gravid uterus, overdistended with excess amniotic fluid, and a twin gestation were believed to have been related causally to the observed renal failure.
Two cases of acute polyhydramnios complicating twin pregnancies were treated with repeated amniocentesis for the relief of extreme abdominal discomfort and to prevent imminent premature labor. The procedure was found to be safe and resulted in prolonging the pregnancies by 14 to 11 days respectively. This management, with the addition of tocolysis and close fetal surveillance (which resulted in 2/4 living children) can offer some hope in an otherwise hopeless situation.
Acute idiopathic polyhydramnios recurred in four pregnancies. Laboratory and ultrasonographic examinations did not reveal the underlying pathology, and no anomalies were found in the infants.
By direct fetal electrocardiography an arrhythmic pattern comparable with parasystolia was observed during the 38th week of pregnancy. The gestational course was only complicated by polyhydramnios. The record of the FHF was considerably disturbed. The normocardic pattern showed poor irregularity, rarely accelerations and decelerations during labor activity. The ectopic QRS-complex was broadened (0,06--0,08 sec) and frequently raised. Beginning the record the frequency of the parasystolia was lower than the activity of the sinus node. A hydropic neonate was delivered by vacuum and died after bradyarrhythmia 37 minutes after parturition. In spite of intensive clarification the cause of pathology was not detected.
A patient with acute polyhydramnios in two successive pregnancies is described. In both this case and the only previously reported similar one, management by frequent transabdominal removal of relatively small amniotic fluid volumes was associated with prolongation of pregnancy and a living infant, suggesting that multiple amniocenteses can improve the otherwise hopeless prognosis associated with acute polyhydramnois.
Polyhydramnios detected in a pregnancy should always be investigated thoroughly. We believe chromosomal abnormalities should be excluded, but that determination need not delay therapy. Indomethacin has been shown to reduce amniotic fluid volume in certain cases, but a strict monitoring schedule should be followed whenever it is administered. At our institution, we are investigating the effect on the fetus of newer, more selective prostaglandin synthetase inhibitors that should have beneficial effects similar to indomethacin, but be devoid of its unwanted side effects.
We report two brothers who were born after pregnancies characterized by polyhydramnios and hypokinesia. Both had brain malformation (absence of corpus callosum in one; arhinencephaly in the other), telecanthus and narrow palpebral fissures. This family and several similar phenotypes reported only in affected brothers could reflect X-linked inheritance.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A case of fetal pleural effusion in a fetus affected with Duchenne muscular dystrophy (DMD) is reported. This case is discussed in the context of the previous observation of frequent stillbirths among male fetuses in DMD families.
Explore the source record for details and available documents.