Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “POSTOPERATIVE COMPLICATIONS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 181 records · Page 10Linked to original sources
PubMedDate not supplied

Postoperative complications following gastrectomy for gastric cancer during the last decade.

BACKGROUND/AIMS: The reduction in the incidence of severe postoperative complications has resulted in a significant increase in the survival of patients with gastric cancer. METHODOLOGY: A total of 879 patients undergoing gastrectomy for gastric cancer during the last decade were retrospectively evaluated for postoperative complications, mortality and associated risk factors. RESULTS: The most frequent complications were anastomotic leakage (3.0%) and wound infection (2.8%) followed by the development of pancreatic fistulae (2.2%) and intra-abdominal abscesses (1.5%). Multiple logistic regression analysis identified various independent risk factors including the extent of lymph node dissection (D1D2 vs. D3) for anastomotic leakage (RR 3.6, P<0.05), splenectomy or distal pancreatosplenectomy for pancreatic fistulae (RR 27.4, P<0.0001) and operative time (360 min < or =) for intra-abdominal abscess (RR 4.8, P<0.05). In total, fourteen patients (1.6%, n=879) died from postoperative complications, with 5 patients dying following non-curative gastrectomy (5.6%, n=90). The complications most associated with death were anastomotic leakage (4 patients) and pneumonia (2 patients). CONCLUSIONS: In view of the potential risk of complications, we should carefully evaluate the indications for aggressive lymph node dissection and/or combined resection of neighboring organs as well as non-curative gastrectomy.

Anastomosis, Surgical↗
PubMed2004

Early postoperative complications following liver transplantation.

Liver transplantation is a highly successful treatment for patients with end-stage liver disease and acute liver failure. However, serious postoperative complications can significantly compromise patient survival. Complications can be technical, medical, or immunological in nature. The risk of developing early postoperative complications is associated with the patient's preoperative condition, the quality of the donor liver, the quality of the donor and recipient procedure, initial graft function, and perioperative anaesthesiological and intensive care management. The patient's preoperative condition can include gastrointestinal bleeding, acute renal failure, a requirement for cathecholamines or mechanical ventilation, and prolonged encephalopathy for the most detrimental risk factors for developing early postoperative complications. The necessity for prolonged mechanical ventilation or the requirement for reintubation after transplantation can significantly increase the risk of developing pneumonia, sepsis, and multiple organ dysfunction. A decrease in infectious and other complications can be achieved by early postoperative enteral nutition, including the application of probiotics.

Constriction, Pathologic↗
PubMed1986

Factors associated with postoperative complications in diabetics after biliary tract surgery.

We reviewed all first operations for cholelithiasis at the North Carolina Memorial Hospital from 1973 to 1982 to assess factors associated with postoperative morbidity in diabetics after biliary tract surgery. Diabetics (n = 126) had more frequent postoperative complications (24.6% vs. 12.5%, p less than 0.001) and higher mortality (7.9% vs. 3.0%, p = 0.02) than the nondiabetics (n = 855). Postoperative complications were more frequent in diabetics at both emergency surgery (57.9% vs. 39.1%) and at nonemergency surgery (18.7% vs. 10.2%). Diabetics were older, however, and had more preoperative renal, cardiovascular, and neurologic disease. We used logistic regression analysis to adjust for these differences and to determine independent predictors of postoperative complications. Urgent surgery, operation other than cholecystectomy, cardiovascular disease, and male sex were associated with an increased risk of postoperative morbidity. Diabetes was associated with an increase in risk that was not statistically significant. We conclude that diabetics have increased morbidity primarily because they are older and have other medical problems. The risk conferred by uncomplicated diabetes is modest, and recommendations for prophylactic surgery in asymptomatic diabetics with gallstones should be reexamined in this light.

Cholelithiasis↗
PubMed2006

The relationship between pre-operative symptoms, operative findings and postoperative complications in schwannomas.

This study presents a retrospective review of the management of schwannomas in the limbs and examines the relationship between pre-operative clinical examination, operative findings and postoperative neurological complications. Eighteen tumours with a histological diagnosis of schwannoma in 17 patients who underwent surgery between 1998 and 2004 were the basis of this study. Enucleation of the tumour was possible in 14 cases. None of these patients had neurological complications pre-operatively but eight had mild neurological complications postoperatively. The complications consisted of sensory deficit in five cases, motor weakness in one and both in two. Enucleation of the tumours was impossible in four cases. These schwannomas originated in the brachial plexus in three cases and the ulnar nerve in the proximal arm in one case. Tumours with pre-operative symptoms and masses located at a proximal site in the limb were more likely to be impossible to enucleate completely.

Adult↗
PubMed2003

Effects of early postoperative complications and the location of trephined block on long-term intraocular pressure control after trabeculectomy.

BACKGROUND: Complications of trabeculectomy in eyes with primary open-angle glaucoma (POAG) and exfoliation glaucoma (EG) were compared. The effects of complications and the location of the trephined tissue block on the long-term success were evaluated. METHODS: One hundred thirty-eight consecutive eyes with POAG or EG of patients over 40 years of age operated on by one surgeon by trabeculectomy without using antimetabolites were analyzed retrospectively. Early postoperative complications and any additional postoperative procedures were recorded and related to the final outcome. In 118 eyes the location of the trephined tissue block was defined in a light microscopic study as anterior or posterior. The success rates in these two groups were determined by Kaplan-Meier survival curves, and the complication rates were compared. RESULTS: Postoperative complications were equally common in POAG and EG, except for hyphema, which was significantly more common in EG than in POAG. Of the early complications, only insufficient filtration at the end of the 1st postoperative month was significantly associated with failure in the long term. The location of trabeculectomy did not significantly affect the early postoperative complications or the long-term success. CONCLUSIONS: Early postoperative complications after trabeculectomy were common, but the only significant predictor of failure was increased intraocular pressure at the end of the 1st postoperative month.

Adult↗
PubMed2003

[Intra- and postoperative complications in the arthroscopy of the knee joint].

Arthroscopy of the knee joint is one of the invasive surgical procedures that are connected with a relatively low risk of complications. Currently it is considered that in the group of diagnostic arthroscopies and technically simple operative arthroscopies all possible complications (less and more serious) account for 0.8-1.2% and in technically more advanced operations performed by means and under control of arthroscopy--1.5-5%. The purpose of this study was a retrospective analysis of intra- and postoperative complications in 10,770 arthroscopies performed in the years of 1986-2001. In our material a number of 731 (6.98%) various complications was observed. General complications (anaestesiological and cardiovascular) represented 0.15%, intraoperative complications--0.31% and postoperative complications--6.34%.

Adolescent↗
PubMed1986

Distant arterial thromboembolization as a postoperative complication of cataract extractions.

This paper describes and analyzes an almost-unreported postoperative complication. Arterial thromboemboli are a concern with hospital populations, where their relative incidence is higher than in the general population. Four case reports are mentioned: Each patient underwent a cataract extraction and, following time periods varying from one day to two months, sustained a thrombosis of a main leg artery. Possible etiologies are discussed. All patients had an impaired immune status in some way, and either this or the resultant steroid treatment may be implicated in their postoperative complication. All patients had cardiovascular histories, and two had previous duodenal ulcers.

Aged↗
PubMedDate not supplied

Assessment of surgical residents' competence based on postoperative complications.

The aim of this prospective study was to evaluate surgical residents' operative skills on the assumption that differences in training might have a significant effect on postoperative complications, their type and incidence. This was accomplished using a departmental microcomputer and special non-commercial personally-developed software. There was no significant clinical difference found in the postoperative complication rate in matched groups of patients treated by senior staff and resident staff of the Department. It is suggested that the close supervision by the senior staff might play a role in this outcome. Although analysis of subgroups of patients sustaining moderate to severe postoperative complications showed a statistically significant difference between these surgeon categories, we may consider this difference attributable to the more complex operative problems handled by the senior staff in the same circumstances.

Female↗
PubMed2004

Surgical technique and postoperative complications in pediatric cataract surgery: retrospective analysis of 21 cases.

AIM: To evaluate postoperative complications of different surgical techniques for cataract treatment in children. METHODS: We reviewed clinical records of 21 children (33 eyes) who underwent cataract surgery between January 1998 and December 2002. The median age of children at the time of cataract surgery was 39 months (range, 4-115 months). The median follow up was 26 months (range, 6-58 months). A posterior continuous curvilinear capsulorhexis with anterior vitrectomy was performed in 24 eyes, and posterior continuous curvilinear capsulorhexis without anterior vitrectomy in 9 eyes (children older than 7 years). Nine eyes were left aphakic and intraocular lens was implanted in 24 eyes. RESULTS: Opacification of the visual axis was the most frequent complication. One of nine eyes in the group of children undergoing posterior continuous curvilinear capsulorhexis developed posterior capsule opacification. This also occurred in 6 out of 24 eyes with posterior continuous curvilinear capsulorhexis and anterior vitrectomy. In 5 eyes with secondary opacification Nd:YAG laser capsulotomy was performed as a secondary procedure. In uncooperative children (2 eyes) more extensive anterior vitrectomy was repeated. Other postoperative complications included aphakic glaucoma (n=1), synechia formation (n=4), intraocular lens deposits (n=2), and pupil capture (n=1). CONCLUSIONS: The main complication in the pediatric cataract surgery was posterior capsule opacification, and the management of posterior capsule seems to be a very important factor. In younger children, cataract surgery with posterior capsulorhexis and anterior vitrectomy was advantageous, whereas in older children a clear visual axis was achieved without vitrectomy.

Capsulorhexis↗
PubMed2004

[Respiratory risk factors in development of postoperative complications after lung resection].

The objectives of the study were to identify possible associated respiratory risk factors and to assess incidence of overall postoperative complications after lung resection. We reviewed 110 patients undergoing lung resections because of malignant neoplasms or benign lung diseases. The risk of postoperative complications was evaluated using unuvariate analysis. Results confirmed that low FEV1, postoperative high PaCO2, ASA-status and advanced age were factors associated with development of postoperative complications.

Aged↗
PubMed2000

Donor and recipient postoperative complications in living related kidney transplantation. A multicentric study.

BACKGROUND: Living related kidney transplantation is considered a gold standard of renal transplantation in order to overcome end-stage renal disease within the same family members. Living donation, albeit decreasing cadaveric donor shortage, exposes donors to the risk of surgical complications. METHODS: In order to assess the postoperative complication rate in donors and recipients, we reviewed retrospectively 90 consecutive living related kidney transplants in a multicentric study. All nephrectomies were performed extraperitoneally through a left flank incision. RESULTS: Major perioperative complications (first 3 weeks after surgery) occurred in 12 subjects: these included bleeding (2.2%), symptomatic pneumothorax (1.1%), iliac thrombophlebitis (3.3%), iliac artery dissection (1.1%), laparotomic dehiscence (2.2%), perirenal hematoma (1.1%), renal artery stenosis (1.1%), urinary fistula (1.1%). Minor perioperative complications took place in 8 cases. One recipient died. Donor postoperative major complications occurred in 2 subjects. CONCLUSIONS: On the basis of these results we conclude that living related kidney transplantation is an important treatment of end stage renal disease, due to the associated low major complication rate and the high feasibility of this methodology.

Adolescent↗
PubMed2004

Registration in the danish hip arthroplasty registry: completeness of total hip arthroplasties and positive predictive value of registered diagnosis and postoperative complications.

BACKGROUND: There are few publications regarding the validity of data in hip arthroplasty registers. The Danish Hip Arthroplasty Registry (DHR) is a nationwide clinical database of THAs and revisions in Denmark. PATIENTS AND METHODS: We assessed the completeness of registration of primary total hip arthroplasties (THAs) and revisions in the DHR from 1995-2000. In addition, the positive predictive value (PPV) of registered data for diagnoses in patients undergoing primary THA and postoperative complications was analyzed. Completeness was assessed using the Danish National Registry of Patients (NRP) as a reference, which is a nationwide and population-based registry of all somatic hospital admissions since 1977. The positive predictive value of registered data was assessed by review of medical records and preoperative radiographs from samples of randomly selected patients registered in the DHR using a standardized form. RESULTS: The overall completeness of registration for primary THAs and/or revisions was 94% (26,129 patients registered in both NRP and DHR and 27,757 patients registered in the NRP). There was a lower degree of completeness for revisions than for primary THAs (81% versus 94%). The completeness did not vary substantially according to gender and age. Completeness of registration was lower for university hospitals than for other hospitals (91% versus 95%), and for low-volume hospitals (87%) relative to those with medium (92%) and high volumes (96%). Overall, the diagnoses in patients undergoing primary THA could be confirmed in 84% (387/459) of the patients who were reviewed. The diagnosis of fresh fracture of the proximal femur was confirmed in only one third (22/73) of the cases. Postoperative complications were confirmed in two-thirds (36/54) of the patients reviewed. The specificity of the registration of postoperative complications was, however, only one-third (8/26). INTERPRETATION: We conclude that the Danish Hip Arthroplasty Registry is a potentially valuable tool for quality improvement and research due to the high degree of completeness of registrations regarding THA, and its moderate-to-high positive predictive value of registration for diagnoses in patients undergoing primary THA. However, information on several diagnoses for primary THA and on postoperative complications should be used with caution.

Aged↗
PubMed2001

Microheterogeneous changes of the C1-esterase inhibitor in plasma cannot predict operability, postoperative complications, or recurrence in cancer surgery.

OBJECTIVE: To find out if microheterogeneous changes--such as in molecular weight, isoelectric point, electrophoretic mobility, lectin binding or complexation of the C1-esterase inhibitor--exist in plasma samples from various subgroups of patients. If so, whether these differences could be used diagnostically in single plasma samples from patients with cancer for prognostic assessment of operability or risk of recurrence, and whether any change indicated an increased risk for development of postoperative complications. DESIGN: Retrospective study. SETTING: University hospital, Sweden. SUBJECTS: 16 patients operated on as emergencies for acute peritonitis, 118 patients electively operated on for benign diseases, 274 patients electively operated on for cancer, and 212 patients admitted with acute abdominal pain. MAIN OUTCOME MEASURES: Curative operation, diagnoses, postoperative complications, recurrence of cancer within 2 years. RESULTS: There were no biochemical differences in the C1-esterase inhibitor between single or sequential plasma samples from four large groups of patients with benign disease, cancer, or inflammatory disease, with operable or inoperable cancer, with postoperative complications or not, or with or without early recurrence of cancer. CONCLUSIONS: Specialised biochemical analyses of C1-esterase inhibitor, the most important plasma protease inhibitor of the complement and kinin systems and of contact activation in plasma, cannot be used for prognostic assessment of operability, risk of postoperative complications, or risk of recurrence in patients with cancer.

Abdomen, Acute↗
PubMed1993

Randomized evaluation of pulse oximetry in 20,802 patients: II. Perioperative events and postoperative complications.

BACKGROUND: The authors describe the effect of pulse oximetry monitoring on the frequency of unanticipated perioperative events, changes in patient care, and the rate of postoperative complications in a prospective randomized study. METHODS: The study included 20,802 surgical patients in Denmark randomly assigned to be monitored or not with pulse oximetry in the operating room (OR) and postanesthesia care unit (PACU). RESULTS: During anesthesia and in the PACU, significantly more patients in the oximetry group had at least one respiratory event than did the control patients. This was the result of a 19-fold increase in the incidence of diagnosed hypoxemia in the oximetry group than in the control group in both the OR and PACU (P < 0.00001). In the OR, cardiovascular events were observed in a similar number of patients in both groups, except myocardial ischemia (as defined by angina or ST-segment depression), which was detected in 12 patients in the oximetry group and in 26 patients in the control group (P < 0.03). Several changes in PACU care were observed in association with the use of pulse oximetry. These included higher flow rate of supplemental oxygen (P < 0.00001), increased use of supplemental oxygen at discharge (P < 0.00001), and increased use of naloxone (P < 0.02). The rate of changes in patient care as a consequence of the oximetry monitoring increased as the American Society of Anesthesiologists physical status worsened (P < 0.00001). One or more postoperative complications occurred in 10% of the patients in the oximetry group and in 9.4% in the control group (difference not significant). The two groups did not differ significantly in cardiovascular, respiratory, neurologic, or infectious complications. The duration of hospital stay was a median of 5 days in both groups (difference not significant). An equal number of inhospital deaths were registered in the two groups. Questionnaires, completed by the anesthesiologists at the five participating departments, revealed that 18% of the anesthesiologists had experienced a situation in which a pulse oximeter helped to avoid a serious event or complication and that 80% of the anesthesiologists felt more secure when they used a pulse oximeter. CONCLUSIONS: This study demonstrated that pulse oximetry can improve the anesthesiologist's ability to detect hypoxemia and related events in the OR and PACU and that the use of the oximeter was associated with a significant decrease in the rate of myocardial ischemia. Although monitoring with pulse oximetry prompted a number of changes in patient care, a reduction in the overall rate of postoperative complications was not observed.

Adult↗
PubMed1997

The current status of postoperative complications and risk factors after a pulmonary resection for primary lung cancer. A multivariate analysis.

OBJECTIVE: The purpose of the present study is to identify the current postoperative complications after a pulmonary resection for primary lung cancer and the associated risk factors. METHODS: From 1988 to 1992, 291 patients with primary lung cancer, excluding T4 diseases, consecutively underwent a pulmonary resection at our institute. The observed postoperative complications were divided into non-life-threatening ones (simple arrhythmia, atelectasis, liver dysfunction, etc.) and life-threatening ones (respiratory failure, pyothorax, pneumonia, bronchopleural fistula, cardiac failure, cerebral infarction, myocardial infarction, etc.). Using logistic regression procedures, both univariate and multivariate analyses of the association between various perioperative factors and the incidence of postoperative complications were performed. RESULTS: Non-life-threatening complications occurred in 60 patients (20.6%) while life-threatening ones occurred in 36 (12.4%), and resulted in five in-hospital deaths (1.75%). Multivariate analyses showed that an age of 70 or older, a combined resection, an abnormality on preoperative ECG, and diffusing capacity of carbon monoxide (%DLco) below 70 were all independently associated with an increased non-life-threatening morbidity. On the other hand, an age of 70 or older, the need for a pneumonectomy, and a %DLco below 70 were also independently predominant risk factors for life-threatening morbidity. CONCLUSION: The risk factors for life-threatening morbidity therefore did not completely correspond to those for non-life-threatening morbidity. Since the mortality was quite low, even risk factors for life-threatening morbidity were not solely considered to be a contraindication for a major pulmonary resection.

Adult↗
PubMed1982

[Malnutrition and postoperative complication rate in cancer patients (author's transl)].

The nutritional status and skin reactivity of 82 cancer patients were determined before surgery and compared with the postoperative complication rate. The nutritional status of 47 patients was evaluated by weight, height, weight-loss, arm muscle circumference, triceps skin-fold measurements, serum albumin, pre-albumin, retinolbinding protein, tranferrin, and cholinesterase. In 35 patients protein catabolism was assessed by the urea production rate (catabolism greater than 15 g/d). Immunity was assessed by the total lymphocyte count and a skin reactivity test. Using these criteria, 55% of the patients were malnourished. Curative operations could only be carried out in 17.4% of the malnourished, but in 50% of the normally nourished patients (P less than 0.0001). Postoperative complications were increased in malnourished patients (47%) when compared with normally nourished patients (20%, P less than 0.05). In anergic and malnourished cancer patients no curative surgical treatment was possible. Due to the increased postoperative complication rate in malnourished cancer patients, nutritional assessment, including the determination of cellular immunity should be performed after admission.

Body Height↗
PubMed2006

[Analysis of postoperative complications of radical hysterectomy for 219 cervical cancer patients].

OBJECTIVE: To analyze the causes and therapeutic approaches for the complications of radical hysterectomy plus pelvic lymphadenectomy in cervical cancer patients. METHODS: From Jan. 1995 to Dec. 2003, 219 such patients were treated by radical hysterectomy plus pelvic lymphadenectomy. The stages were: 26 stage IA (17 stage IA1 and 9 stage IA2) (11.9%); 142 stage IB (78 stage IB1, 64 stage IB2) (64.8%); 40 stage IIA (18.3%) and 3 stage IIB (1.4%). 204 patients in this series were treated by radical hysterectomy plus pelvic lymphadenectomy and 15 by modified radical hysterectomy with pelvic lymphadenectomy. RESULTS: a total of 49 patients (22.4%) developed postoperative complications. The major complications included: bladder dysfunction (10.0%); formation of lymphocysts (7.8%); wound infection (6.8%); hydronephrosis (1.4%) and formation of ureteral fistulas (0.5%). The patients in the group treated by radical hysterectomy plus pelvic lymphadenectomy was likely to develop postoperative complication compared with the patients in the group by modified radical hysterectomy plus pelvic lymphadenectomy (24.0% versus 0, P = 0.067). The postoperative complication incidence in the patients who had preoperative neoadjuvant chemotherapy through intra-arterial catheter or radical radiotherapy in the other hospitals were 50.0% (2/4) and 100.0% (1/1), which were higher than that of the patients treated primarily in our hospital (21.3%, 25.3%) though without statistically significant difference among the groups. Of 52 patients who had previous abdominal surgery history, 13 developed posoperative complications, there was no significant difference between the patients with or without previous abdominal surgery history. The complication incidence of 87 patients treated with preoperative afterloaded radiotherapy was higher than that of 124 patients primarily treated by surgery (25.3% versus 19.4%), but the difference between two groups was statistically not significant (P = 0.239). CONCLUSION: The complication of radical hysterectomy with pelvic lymphadenectomy is correlated with the surgery mode. Preoperative afterloaded radiotherapy may not increase postoperative complication incidence. Properly reducing the extent of surgery may decrease incidence of complications.

Adolescent↗
PubMed1999

Visual results and postoperative complications of capsular bag and ciliary sulcus fixation of posterior chamber intraocular lenses in children with traumatic cataracts.

PURPOSE: To evaluate the visual results and postoperative complications of capsular bag and ciliary sulcus fixation of posterior chamber intraocular lenses (IOLs) for traumatic cataracts in children. SETTING: Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. METHODS: Twenty children (20 eyes) with traumatic cataracts had extracapsular cataract extraction (ECCE) and posterior chamber IOL implantation. They were randomly divided into 2 groups. Capsular bag fixation was performed in 10 children (Group A) and ciliary sulcus fixation in the other 10 (Group B). Traumatic cataracts associated with large corneal lacerations (10.0 mm or more), hyphema, angle recession, or posterior segment involvement were excluded. The best corrected visual acuity (BCVA) as well as early and delayed postoperative complications were prospectively evaluated in both groups. RESULTS: The BCVA was 6/12 or better in 9 eyes (90%) in Group A and 8 eyes (80%) in Group B at the end of the mean follow-up (24.6 months +/- 10.6 [SD]). Amblyopia (1 eye in Group A) and corneal scar and commotio retinae (1 eye each in Group B) accounted for a visual acuity of worse than 6/12. The residual refractive error did not exceed 3.50 diopters in either group. The incidences of fibrinous anterior uveitis and pupillary capture were significantly higher in Group B (P < .05, Fisher exact test). CONCLUSION: Capsular bag fixation of posterior chamber IOLs provided visual results similar to those with ciliary sulcus fixation but was associated with fewer postoperative complications, particularly uveitis and pupillary capture. This represents another important reason to attempt in-the-bag fixation in cases of traumatic cataract.

Cataract↗