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At least 181 records · Page 10Linked to original sources

Myositis ossificans masquerading as a recurrent spindle cell lipoma of the orbit.

A spindle cell lipoma developed in the right orbit of a 43-year-old woman whose medical history was only significant for chronic asthma. Sixteen months after nearly complete excision of the tumor, the patient presented with eyelid swelling, orbital pain, and a calcified apical mass as demonstrated by computerized tomography (CT). Recurrent tumor or a second neoplasm was suspected. Histologic examination revealed myositis ossificans. To our knowledge, this is the first reported case of myositis ossificans in the orbit.

Adult↗

Myositis ossificans of traumatic origin in the foot.

This case reviews a myositis ossificans of traumatic origin discovered beneath the fifth metatarsal in an adult male. Details of its anatomic appearance are illustrated with the assistance of plane film roentgenography and magnetic resonance imaging. Histologic sections are included to support the diagnosis and present characteristic cellular patterns. A review of the literature including etiology, clinical classification, and diagnostic criteria are also presented.

Aged↗

[Circumscribed spinal myositis ossificans of infections origin].

A case of paravertebral, non-traumatic myositis ossificans in a 4.5 year-old boy is reported. Infectious spondylitis and osteosarcoma were considered before the diagnosis was established on the basis of histological examinations of a biopsy performed during excision. A group G beta hemolytic streptococcus was isolated from the biopsy, suggesting an infectious etiology which has rarely been reported. The child appears to be completely cured one year after excision.

Child, Preschool↗

[Progressive myositis ossificans. Utility of bone scintigraphy].

47 year old woman affected by myositis ossificans, with muscular calcifications in her evolution. Bone scintigraphy showed increased polyfocal activity as well as uptake of different intensity in soft tissues. The bone scintigraphy allows for early identification of ossification areas in soft tissues, as it can even detect injuries earlier than that observed with other image techniques. It is considered to be very useful in the diagnosis and establishment of the extension of the process, as well as follow-up.

Ankylosis↗

The subcutaneous fascial analogue of myositis proliferans: electron microscopic examination of two cases and comparison with myositis ossificans localisata.

Two cases of the so-called fascial analogue of myositis proliferans were investigated by histological and electron microscopic methods. It was found that the structure of the fascial variant corresponds almost completely to the true myositis proliferans localized within the musculature. The electron microscopic observations show a preponderantly histiocytic differentiation of the cells and strongly activated proliferating capillaries, and exclude a myogenic origin of the characteristic ganglion-like giant cells. Ultrastructurally a traumatic genesis appears possibly, the cells of the lesion could derive from multipotent cells of the microvasculature. The relations to myositis ossificans and fascitis nodularis are discussed.

Adult↗

Induction of recurring myositis ossificans by intrathymic injection of 3-methylcholanthrene-treated cells in rats.

Studies were performed to ascertain the effects of transplantation of thymic cells exposed in vivo to 3-methylcholanthrene (3-MC) on the induction of malignancies in Copenhagen rats. Three recipient rats unexpectedly developed tumors which bore histological resemblance to myositis ossificans of humans. Specifically, histology revealed areas of peripheral ossification with the appearance of zones of primitive osteoid with a central cellular area. Other areas of the lesions were less well organized into characteristic zones or were more or less heterogeneous. The primary, as well as recurring, lesions appeared in the axilla and were well circumscribed, 24-68 g in weight and 2-7 cm in diameter. Flow cytometric analyses of DNA content indicated that these tumors contained cells with abnormal DNA characteristics as well as proliferating cells. Coupled with the observation that after excision these tumors recurred, the data suggest that these myositis ossificans lesions were malignancies.

Animals↗

Myositis ossificans of the thigh following manipulation of the knee. A case report.

Myositis ossificans of the thigh produced severe limitation of knee motion in a 22-year-old man after passive manipulation of a knee on three separate occasions. Motion improved after excision of the bony mass and postoperative radiation to prevent recurrence. Caution is advised in passive manipulation of the knee, because repeated attempts can result in forced extension of the quadriceps muscle, periosteal damage, partial muscle tears, and interstitial hemorrhage.

Adult↗

Myositis ossificans in children: description of a clinical case with a rare localization.

Myositis ossificans (MO) also defined as myosteosis or hematoma ossificans, is a benign condition presenting as an heterotopic, well- defined neoformation in muscles and soft tissues. It was first described by Guy Patyn in 1692 and defined in its histopathological aspects by Von Dusch in 1868. It most frequently has a post-traumatic onset (60-75% of cases), usually following small repeated traumas or a single bruising episode. MO is rare in subjects under 10 years of age, whereas it is more frequent in teen-age athletes, and over 50% of cases are diagnosed in the third decade of life. Its etiopathogenesis in unknown, although it is associated with a traumatic event in 75% of cases. MO most common localizations are arms, legs, shoulders and hands, rarely chest. The lesion presents with different degrees of maturation and diagnostic tools are echotomography (ECT) as a primary investigation, and NMR for a better diagnostic assessment. Because of the self-limiting nature of the lesion and its spontaneous resolution, a conservative treatment is advised along with radiological follow-up which is most indicated in the presence of either typical MO features or highly suggestive ECT o NMR findings. In case of uncertain diagnosis, relevant muscular function impairment, considerable lesion dimension or severe pain, exeresis and histological examinations are suggested. The present paper describes and discusses a clinical case of MO in a child, with a rare localization.

Child↗

Fine-needle aspiration biopsy cytology of myositis ossificans.

Increased utilization of fine-needle aspiration cytology to better define mass lesions before surgical excision can occasionally expose a cytologically worrisome yet biologically benign proliferative process. Such a proliferation may mimic a malignant neoplasm but is actually benign. Because of its limited exposure in the literature, we describe the cytopathology of two cases of myositis ossificans obtained by the fine-needle aspiration biopsy technique. Both lesions occurred in adolescents. One involved the deep muscle of the thigh, whereas the other was a superficial lesion of the anterior abdominal subcutaneous fat. In both instances a benign entity was favored, but in one case sarcoma could not be absolutely excluded by fine-needle aspiration cytology. Follow-up surgical excision in one case, and incisional biopsy in the other confirmed the diagnosis of myositis ossificans (MO). The cytologic differential diagnosis of this lesion is discussed.

Adolescent↗

Myositis ossificans in an infant.

We report a 15-month-old girl with myositis ossificans at the shoulder. Because of the unusual presentation at this age the differential diagnosis with osteomyelitis or a tumoral process had to be considered. It had a benign evolution without specific treatment.

Clavicle↗

Traumatic myositis ossificans of the superior belly of the omohyoid.

The first case of traumatic myositis ossificans (TMO) involving a strap muscle of the neck is reported. TMO typically presents with an unresolved mass following trauma or surgery, requiring differentiation from other soft tissue and bone neoplasms. Opacification may be present on soft tissue X-rays. Computed tomography (CT) scan may demonstrate a characteristic zoning phenomenon to establish the diagnosis. The disorder is frequently self-limiting but surgery may be required for persistent symptoms.

Adult↗