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Life-table analysis of progression to diabetes of anti-insulin autoantibody-positive relatives of individuals with type I diabetes.

Cytoplasmic islet cell antibody-negative (ICA-; less than 20 Juvenile Diabetes Foundation units, n = 1670) and ICA+ (n = 42) first-degree relatives of type I (insulin-dependent) diabetic individuals were studied for competitive insulin autoantibodies (CIAAs) with a radioassay. Overall, 3.7% of first-degree relatives (64 of 1712) were CIAA+. Of ICA- relatives, 2.7% (45 of 1670) exceeded the upper limit of our normal CIAA range (greater than 39 nU/ml), and 45% (19 of 42) of ICA+ relatives exceeded this normal range. Follow-up serums for repeat CIAA determination have been obtained from 16 of the nondiabetic CIAA+/ICA- individuals (time between samples, 0.4-5.8 yr). Fourteen of these 16 (87%) CIAA+/ICA- relatives were found to still be positive on follow-up, and 2 of the relatives who were positive on the first determination were negative on their follow-up test. With a mean follow-up of approximately 2 yr, 4 of 45 (9%) of the CIAA+/ICA- relatives, 5 of 23 (22%) of the ICA+/CIAA- relatives, and 12 of 19 (63%) of the CIAA+/ICA+ relatives developed diabetes. Life-table analysis indicated that, overall, 53% of CIAA+ relatives become diabetic after 5 yr of follow-up versus 65% of ICA+ relatives. Also by life-table analysis, the predicted risk after 5 yr of follow-up for progression to diabetes is 17% for CIAA+/ICA- relatives, 42% for ICA+/CIAA- relatives, and 77% for CIAA+/ICA+ relatives. The highest rate of progression to diabetes was found in ICA+ relatives with CIAA levels greater than 150 nU/ml (100% projected to be diabetic within 5 yr, P less than .008 vs. ICA+/CIAA- relatives).

Autoantibodies↗

Biology, life table and host specificity of the mushroom pest, Brennandania lambi (Acari: Pygmephoroidea).

Biology and life table parameters of Brennandania lambi (Krczal) were studied at different temperatures while feeding on white mushroom (Agaricus bisporus) mycelium cultured on mushroom compost. The duration of egg and larva development, preoviposition and oviposition period, female longevity, and the time to 50% mortality declined as temperature increased from 16 to 28 degrees C. The threshold temperature of development (female) was 9 degrees C and the thermal constant for completion of development (female) was 195 day-degrees. At 16, 20. 24 and 28 degrees C, the total fecundity (eggs/female) was 71, 67, 66 and 57, respectively and the daily fecundity rate (eggs/female/day) was 5.6, 8.7, 8.7 and 9.1, respectively. The sex ratio (female/male) ranged from 1.9 to 2.1 at 16-28 degrees C. At 16, 20, 24 and 28 degrees C, the intrinsic rate of natural increase (rm) was 0.11, 0.18, 0.22 and 0.27, respectively, and the population doubling time was 6.1. 3.9. 3.2 and 2.5 days, respectively. All life stages of the mite died when exposed to 35 degrees C constant temperature for 24h. or to 32 degrees C constant temperature for 12 days or to 31-35 degrees C (average 32.9 degrees C) ambient temperature for 4 days. Brennandania lambi completed development only when fed on Ag. bisporus mycelium growing on mushroom compost. It could not survive on mushroom mycelia of Auricularia auricula. Au. polytricha, Ganoderma lucidum, Hericium erinaceus, Lentinus edodes, Pleurotus ostreatus, P. sajor-caju and Tremella juciformis.

Agaricales↗

[Life table of experimental population Liposcelis bostrychophila].

The age-specific and time-specific life table of experimental population Liposcelis bostrychophila was established at 8 different temperatures (17.5-35 degrees C) and 5 different humidities (50-90% RH). The relations between population dynamics and temperature or humidity were discussed with Morris model and Weibull frequency distribution. The results indicated that the effect of temperature and humidity on survivorship was the most important factor to population trend index (I). Under suitable range of temperature and humidity, the population survival curve belonged to Deevey I; while under improper conditions, it belonged to Deevey III. Theoretically, finite increase rate (lambda) had the highest value 1.0628/day at 30.63 degrees C. The optimum range of temperature and relative humidity for its development and reproduction was estimated at 28-30 degrees C and 80% +/- RH, respectively.

Animals↗

Age-dependent fecundity and fertility life tables of the predator Brontocoris tabidus (Heteroptera: Pentatomidae) under field conditions.

Reproductive potential, longevity, life expectancy, and fertility life tables of Brontocoris tabidus (Signoret) (Heteroptera: Pentatomidae), a predator of lepidopteran defoliators in eucalyptus (Eucalyptus spp.) plantations, were studied in the field. After a 50-d preoviposition period (emergence of adults to the deposition of the first egg mass), ovipositional activity of B. tabidus continued until females died at 160 d. Females laid an average of 4.2 eggs per day and 601.1 eggs in a lifetime. Gross and net reproductive rates were 216.7 and 75.8 females, respectively. Generation time was 146.1 d, the period for doubling the population was 23.4 d, intrinsic rate was 0.03, and finite population increase was 1.03. Number of females per generation increased at 33.4 times. Results from our field studies indicate that B. tabidus has greater potential reproduction, oviposition period, and longevity than was expected from previous laboratory experiments. This suggests that B. tabidus has potential as a biological control agent to limit economically damaging pests in eucalyptus plantations.

Aging↗

Influence of diet on life table parameters of Iphiseius degenerans (Acari: Phytoseiidae).

Abstract. Studies on the reproduction, longevity and life table parameters of Iphiseius degenerans (Berlese) were carried out under laboratory conditions of 25 +/- 1 degree C, 75 +/- 5% RH and 16L:8D h. As food sources for the predatory mite, Ricinus communis L. pollen, all stages of the spider mite Tetrranchus urticae Koch, Frankliniella occidentalis (Pergande) larvae, and Ephestia kuehniella Zeller eggs were selected. All diets were accepted as food by the adult mites. Female longevity ranged from 29.5 to 42.4 days, the highest value was recorded on a diet of Ephestia eggs. The highest percentage of females escaping the experimental arena was observed on the diet consisting of thrips larvae. The highest oviposition rate (1.9 eggs/female.day) was recorded when the predator was fed on spider mites on an artificial substrate. For other diets, oviposition rates ranged from 1.0 to 1.3 eggs/female.day. The intrinsic rate of natural increase (r(m)) of I. degenerans varied between 0.015 and 0.142 females/female x day. The diet consisting of castor bean pollen resulted in the highest population growth whereas the diet on spider mites brushed off onto a bean leaf arena resulted in the slowest population growth. This can be explained by the inability of the predator to cope with the webbing of T. urticae, and the high escape rate of the progeny when reared on spider mites. The percentage of females in the offspring ranged from 40 to 73%.

Animals↗

[Life tables. An approximation to their construction].

The method suggested by the World Health Organization on constructing current life tables is described in order to analyse the mortality by age groups and to estimate life expectancy for the Grândola community, between 1990 and 1992. Mortality rates seem to be high in some younger age groups, but a more detailed investigation should be made about their causes and, if possible, appropriate measures should be taken to correct the above situation. Life expectancy at birth was estimated in 67.75 years for males and 77.42 for females, the first being lower than the average of this country. The described method has the main advantage of being mathematically and conceptually simpler than many others existing in literature, with similar final results.

Adolescent↗

Life-table analysis of primary and assisted success following endoluminal repair of abdominal aortic aneurysms: the role of supplementary endovascular intervention in improving outcome.

AIM: the aim of this study was to analyse the effect of supplementary endovascular intervention on the outcome of primary endoluminal repair of abdominal aortic aneurysm (AAA). METHODS: between May 1992 and December 1998, 266 patients underwent endoluminal repair of AAA. Minimum period of follow-up was 6 months. Those patients in whom the endoprosthesis could not be deployed were converted to open repair at the primary operation. Patients developing an early endoleak, within 31 days, were treated by a period of observation and secondary endovascular intervention in persistent cases. Patients developing a late endoleak were treated similarly, without a period of observation. Outcome was analysed by the life-table method. Primary success was defined as exclusion of the aneurysm from the circulation resulting from the original operation. Assisted success occurred when aneurysms with endoleaks became excluded from the circulation as a result of supplementary endovascular intervention. RESULTS: endoluminal repair failed in 17 patients requiring conversion to open repair at the original operation. Supplementary endovascular intervention was undertaken in 26 patients, with early endoleaks (n=6) and late endoleaks (n=20). Interventions involved deployment of secondary endoluminal grafts within the primary grafts (n=22), and coil embolisation (n=4). Successful exclusion of the aneurysm sac was achieved in 22 of 26 (85%) patients undergoing supplementary endovascular procedures. Conditional cumulative incidence of primary graft failure and secondary graft failure in the presence of all-cause mortality at 6 years was 47% and 25% respectively. CONCLUSIONS: supplementary endovascular intervention is an important adjunct to endoluminal AAA repair with the potential to improve outcome and avoid conversion to open repair. Successful supplementary endovascular intervention was achieved in 85% of patients in whom it was attempted. Life-table analysis showed these supplementary procedures to be durable in the long term.

Aged↗

Brazil: model life tables and stable population.

"In the 1974 Meeting of the Brazilian Association for Population Studies, Frias and Leite presented a set of model life tables that were meant to reflect the sex-age structure of Brazilian mortality. A later examination of this study revealed the need for revision and further development in order to improve this valid piece of work." The present article reviews and complements the earlier study.

Age Distribution↗

Convergence in rural-urban patterns of nuptiality and mortality: a life table update.

"Based on 1979-1981 and 1989-1991 [U.S.] vital registration and 1980 and 1990 census data, we construct increment-decrement life tables for rural and urban males and females. The analysis is centered on 1980 and 1990 and describes urban-rural differences in patterns of mortality and nuptiality by age and sex. Our research updates an earlier study that described urban-rural mortality and marital transition patterns for Tennessee, 1970. The 1980 and 1990 findings parallel the 1970 results. Rural women and men have shorter life expectancies; higher infant mortality rates; younger median ages of entry into first marriage, divorce, and widowhood; a greater proportion of their cohorts ever marrying; lower probabilities of divorce; and higher probabilities of widowhood than urban women and men. However, there was a decline in urban-rural differences from 1970-1990. These changes suggest that urbanization, technological advances in communication and transportation, and the diffusion of urban lifestyles and values may have blurred the urban-rural distinction."

Age Factors↗

Marriage and mortality: a life table analysis.

This paper examines the effects of age at marriage and differential mortality of males and females on the incidence of widowhood between the sexes. Abridged life tables constructed from marital status and death registration data of a rural area of Bangladesh for the period 1974-79 were used. The difference in life expectancy between males and females varies from 0.4 to 2.2 years at the ages 0 to 65 years and over. The mortality differentials show that the probabilities of a male or a female surviving the other spouse would be approximately the same, were there no other influence. But the incidence of widows is about ten times that of widowers. Other relevant factors, under a given regime of mortality, are age at marriage and age difference between husband and wife.

Adult↗

[Life table of natural population of banana pseudostem weevil, Odoiporus longicollis Oliver, in spring].

The active factor life tables of natural population of banana pseudostem weevil were built, and the controlling effect of active factors was evaluated by using exclusion index of population control (EIPC). The results showed that the population trend indices in growing and harvested banana trunks were 4,3481 and 3,6628, and the EIPC of predation and others were 1,9256 and 2,3577, respectively. The EIPC of natural death were 1,3607 and 1,3554, and that of parasitism and disease in growing and harvested banana trunks were 1,1988 and 1,1668, respectively. The factor of predation and others was important.

Animals↗

Results of femoropopliteal and femorotibial greater saphenous vein in situ bypass. Life table analysis.

Five-hundred-ninety-four nonselected "in situ" reconstructions were analysed retrospectively using the life table method. Especially after immediate occlusion cumulative patency is very unsatisfactory. After 5 years cumulative patency rate in these cases is 39.5% vs. 64.9% in all cases. Patency rates are influenced by the anastomotic site and the run-off quality. While statistically not significant, popliteal anastomoses perform a little better after 5 years than peripheral anastomoses (67% vs. 51% cumulative patency rate). The number of patent tibial arteries seems to be the most important determinant. In non-occluded run-off cases (three patent tibial vessels) the cumulative patency rate after 5 years is 82.2% vs. 56% in cases with only one patent tibial artery. The difference is statistically significant.

Aged↗

Comparison of life table attributes from newly established colonies of Anopheles albimanus and Anopheles vestitipennis in northern Belize.

A life table study was conducted for recently established colonies of Anopheles albimanus and Anopheles vestitipennis in Belize, Central America. The colonies were reared in the northern Orange Walk District under uncontrolled environmental conditions (29-32 degrees C, 87-90% RH, and 13:11 L:D photoperiod). The mean time of larval development for An. albimanus was 10.8 days for males and 11.7 days for females. Mean times for An. vestitipennis larval development were 11.3 days for males and 13.5 days for females. Anopheles albimanus exhibited a 92% survival rate from egg hatch to adult emergence, while that of An. vestitipennis was 82%. Neither species showed a sex ratio that was significantly different from 1:1. Adult male An. albimanus lived for an average of 13.6 days, while the females lived for an average of 21.2 days. The An. vestitipennis adult males lived for a mean of 14.8 days, while the females lived considerably longer with a mean of 25.6 days. The reproductive rate and age of mean cohort reproduction were calculated as 287 and 11.3 days for An. albimanus and 302 and 13.4 days for An. vestitipennis. The r/B and B/D ratios of 0.13 and 1.15, respectively, for An. albimanus and 0.1 and 1.1, respectively, for An. vestitipennis indicate that these species have a low potential for colonization.

Animals↗

Life table analysis of the United States' Year 2000 mortality objectives.

BACKGROUND: The US Year 2000 mortality objectives are model standards cast as targeted changes in age-adjusted cause-specific death rates. This research centred on the projected impact of such changes on life expectancy and the mortality toll for each sex. METHODS: A computer simulation was conducted using single decrement, multiple decrement and cause-elimination life table techniques, together with a decomposition procedure. RESULTS: Male and female life expectancy at birth was projected to increase by 1.71 and 1.51 years, respectively, between the designated 1987 baseline and 2000. The leading beneficiaries would be those aged 65 and older, followed by those aged 45-64, and infants. Declines in coronary heart disease, stroke and injury death rates would most influence the projected life expectancy changes, irrespective of sex. Approximately 782,000 male deaths and 730,000 female deaths would be averted under Year 2000 assumptions. CONCLUSIONS: Life expectancy would be a useful summary measure to incorporate into official evaluations of the Year 2000 mortality objectives. Targeting of excess male mortality in the US and other highly industrialized nations is recommended.

Adolescent↗

Life tables as "predictors" of average longevity.

Selected figures from Canadian life tables have been analysed to illustrate one potential use of routinely collected and published data. A plea is made for the inclusion of the fundamentals of demography in undergraduate medical education.

Adolescent↗

Multistate life-tables and regression models.

"A survey is given of the use of modern statistical techniques in event history analysis, and in particular in the study of multi-state life-tables in demography. Emphasis is placed on the interplay between partial likelihood and nonparametric maximum likelihood based methods, a) when analysing semi-Markov models or models with repeated spells, and b) in frailty models for unobservable heterogeneity."

Demography↗

Life table tests of evolutionary theories of senescence.

The phenomenon of senescence requires both evolutionary and proximate explanations. The most widely accepted evolutionary explanation for senescence is that it never gets exposed to natural selection because environmental hazards kill all individuals before the age at which senescence causes decreased fitness. If this explanation is sufficient, wild populations should not demonstrate senescence, and their mortality rates should therefore remain constant during adult life, except when environmental causes of mortality have recently decreased. The alternative explanation for the persistence of the genes that cause senescence is that they have been selected for because they have pleiotropic effects that are beneficial early in life when the force of selection is strongest. Where this is the case, mortality rates should increase with age in wild populations. A method is described for using life table data to calculate an estimate of the intensity of selection acting on senescence in wild populations. This method is applied to a variety of life tables. The results suggest that pleiotropic genes may be important causes of senescence in some populations, but not in others. This has implications for research on the proximate mechanisms of senescence.

Aging↗

Tenth revision U.S. mortality rates for use with the NIOSH Life Table Analysis System.

OBJECTIVE: The objective of this study was to update rate files for the NIOSH Life Table Analysis System for Personal Computers (PC LTAS) reflecting the newly adopted tenth revision changes to the International Classification of Diseases. METHODS: PC LTAS allows researchers to conduct comparative mortality and morbidity analyses for the purpose of identifying disease-exposure associations using person-time-at-risk for age, race, sex, and calendar time-specific reference rates from 1940. Previously available through 1998, files for the United States and individual states were updated through 2004 using uncensored population data. Tenth revision causes were added if compatible with earlier NIOSH death categories, based on revisions 5 through 9. A few new cause categories were added. RESULTS: The resulting NIOSH categories are described for two new U.S. rate files: 1960 through 2004 and 1940 through 2004. CONCLUSION: The new U.S. rate files are available online or on request.

Cause of Death↗