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Results for “HYPOGASTRIC PLEXUS”

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At least 181 records · Page 10Linked to original sources
PubMed1971

Sexual function following aortoiliac reconstruction.

Impotence due to atherosclerotic disease of the aorta and iliac arteries presents as failure to achieve erection. Sterility after aortoiliac reconstructive surgery is more common and presents as inability to ejaculate. If the superior hypogastric sympathetic plexus (presacral nerve) is preserved, sexual function can be maintained in 90% of cases.

Adult↗
PubMed1964

THE ACTION OF MORPHINE-LIKE DRUGS ON IMPULSE TRANSMISSION IN MAMMALIAN NERVE FIBRES.

Experiments on nerves in situ and on isolated nerves provide no evidence that morphine interferes with impulse transmission in myelinated or nonmyelinated nerve fibres. The concentrations used in experiments on isolated nerves were 10- to 100-times as high as those required to depress transmission at autonomic nerve-effector cell junctions. Examination of the resting membrane potential, the action potential and the positive after-potential, the conduction velocity, the time courses of the recovery of the size of the action potential and of the excitability after a conditioning stimulus, the ability of the axons to sustain repetitive activity and the posttetanic hyperpolarization gave no indication that morphine affects either the mechanisms involved in the initiation of the propagated impulse or those leading to restoration of the resting state after activity. Analgesic drugs, such as pethidine and methadone which have a local anaesthetic action, may cause a reversible decrease in the size of the compound action potential and in the conduction velocity of A-B and C fibres.

Analgesics↗
PubMed1964

ANGIOTENSIN AND PERIPHERAL SYMPATHETIC NERVE ACTIVITY.

On the isolated vas deferens of the guinea-pig angiotensin potentiated strongly the height of contractions due to electrical stimulation of the hypogastric nerve; it did not affect the responses to noradrenaline and acetylcholine, nor did it elicit any contraction when given alone. Angiotensin likewise potentiated the responses of the cat spleen to nerve stimulation, but it also induced by itself strong contractions of the organ and reduction of the venous outflow. In experiments on the arterial blood pressure of anaesthetized and spinal cats, in which sympathetic postganglionic transmission was temporarily blocked by nicotine or tetramethylammonium, pressor responses to angiotensin were strongly reduced. As with some ganglion-stimulating drugs, the pressor responses, enhanced after a second series of nicotine injections, were reduced to the control level by hexamethonium. These findings indicate the involvement of peripheral sympathetic nerves in the action of angiotensin: the hypothesis is advanced that angiotensin acts at the peripheral nerve endings by promoting a greater output of noradrenaline.

Acetylcholine↗
PubMed1964

THE MECHANISM OF THE PRESSOR RESPONSES TO PHYSOSTIGMINE IN THE RAT AND THEIR MODIFICATION BY MEBUTAMATE AND AMYLOBARBITONE.

Pressor responses to intravenous injections both of physostigmine and of pilocarpine were smaller in rats anaesthetized with either mebutamate or amylobarbitone than in rats anaesthetized with urethane. The response to electrical stimulation of the hypogastric nerve in the isolated hypogastric nerve-vas deferens preparation was diminished by mebutamate and by amylobarbitone, but not by urethane. Similar results were obtained with the cat isolated splenic nerve-spleen preparation. In the rat anaesthetized with urethane, pressor responses to physostigmine were only partially antagonized by hexamethonium but were completely abolished during "depolarizing" ganglionic block by nicotine or tetramethylammonium. It is suggested that, in addition to the central mechanism, there is a peripheral component in the pressor action of physostigmine and in the antihypertensive actions of mebutamate and amylobarbitone.

Ammonium Compounds↗