Human discrimination learning: the subset-sampling assumption.
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The effects of chlorpromazine on the acquisition of a brightness discrimination with food reward were examined. Doses of 0.5, 1.0 or 2.0 mg/kg of CPZ as well as saline were administered intraperitoneally to 4 groups of 7 Sprague-Dawley rats, 1 h prior to testing. After a 3-week period of habituation and pre-training, rats were tested 20 trials a day, 7 days a week. No drug effect was found on the number of trials to reach a criterion of 18/20 successive correct responses, which required an average of 6.2 days of training. Precriterion latencies, however, showed an increase as a function of increasing dose level. Post-choice latencies were not affected, eliminating motor retardation as an explanation for the latency effect.
Monocularly patched rats were trained on a series of visual tilt discriminations ordered from simple to difficult to measure the angular difference threshold of each eye. The stereotyped running pattern which the animal made was also recorded. Callosal section disrupted a preoperatively established running pattern and produced an ocular neglect; the animal's performance dropped to chance when it used the eye ipsilateral to the preferred side of approach.
Offspring were either adequately nourished or undernourished during the suckling period. They had free access to food from weaning, and were given 2 behavioral tests between 13 and 19 weeks of age. Motivation for water was tested on a variable interval (VI) schedule at 3 levels of deprivation and a test of light-dark discrimination made at 23.5 hr of water deprivation. The results indicated (1) no clear difference in VI response rate, but (2) significant differences in discrimination performance between the 2 groups. A learning ability or certain relevant abilities rather than motivation for water appeared responsible for the difference in discrimination learning.
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The relationship between human temporal behavior and learning was investigated by means of an experimental design which measured temporal behavior using the methods of reproduction and production as possible correlates for a complex-form of discrimination-reversal learning. The results indicated that the method of reproduction is a temporal correlate of original learning and that the method of production is a temporal correlate of reversal learning. The theoretical explanations proposed for these results employed the mechanisms of conditioning, extinction, and stimulus generalization, the intervening variables of excitation and inhibition and the Pavlovian levels of behavioral organization of the first and second signalling systems.
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