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Injury surveillance in developing countries.

In both developed and developing countries, injuries have a substantial effect on the public's health and on quality of life. Although epidemiologic data regarding the occurrence of injuries in developing countries are limited, recent studies have documented substantial injury-related morbidity and mortality in some of these countries. For example, recent studies in rural Papua New Guinea showed that injuries are the leading cause of death for persons ages 15-44 years. Similarly, injuries are the leading cause of hospitalization in Indonesia and Egypt. Surveillance of injuries is necessary in order for public health practitioners and planners in developing countries to direct and allocate scarce resources appropriately.

Adolescent↗

Dental services and needs in developing countries.

People in developing countries are burdened excessively by oral diseases, particularly periodontal disease. These are aggravated by poverty, poor living conditions, ignorance concerning health education, and lack of government funding and policy to provide sufficient oral health care workers. WHO and FDI have identified the problems and developed strategies. However, acceptable goals and standards of oral health have to be agreed. Furthermore, barriers to oral health promotion need to be overcome through co-operation at all levels and appreciation of cultural sensitivity. There is the need for research to determine which types of oral health care systems are most effective in reducing the extent of inequality in oral health. In developing countries where there are huge problems, intervention programmes focusing on primary care and prevention should be designed and implemented urgently and their effectiveness monitored and analysed scientifically. The WHO, FDI and national and international professional organisations should play a leading role in encouraging a determined, co-ordinated effort towards improving the oral health status of disadvantaged people in developing countries.

Culture↗

Socioeconomic factors affecting fertility in the developing countries and of the developing population groups in South Africa.

"In the present paper...socioeconomic factors affecting the fertility of the developing population groups in South Africa, are discussed and compared with findings [for developing countries] from the WFS [World Fertility Survey]." Data for South Africa are from an independent survey conducted during 1981-1982. "The relationship between socioeconomic factors and three dependent variables (marital fertility, desired family size, and current contraceptive use) is analysed.... The analyses are restricted to the examination of the extent to which the wife's differentials in fertility and associated variables related to education, employment status, and rural/urban residence persist, when other socioeconomic characteristics of the couple are controlled statistically."

Africa↗

Hepatocellular carcinoma prevention: a worldwide emergence between the opulence of developed countries and the economic constraints of developing nations.

Hepatocellular carcinoma (HCC) is the fifth most common neoplasm, the major cause of death in patients with liver cirrhosis, and the third most common cause of cancer-related death in the world. The geographic distribution of HCC varies significantly and 80% of cases occur in developing countries (Far East and South Asia) where the prevalence of viral hepatitis is higher. The treatment of HCC is difficult because most patients are diagnosed when the tumour is in an advanced stage and is not amenable to potential curative therapy, thus prevention is the key to reducing HCC and its related morbidity and mortality. HCC is unique among cancers, occurring mostly in patients with a known risk factor. Ninety percent of HCCs develop in the context of chronic liver diseases and mainly in patients with cirrhosis. Viral hepatitis is the most common cause of HCC worldwide, followed by alcoholic liver disease (ALD) and other causes such as non-alcoholic fatty liver disease (NAFLD), genetic haemocromatosis (GH) and primary biliary cirrhosis in an advanced stage (III-V). In certain areas of the People's Republic of China, exposure to aflatoxin and HBV infection are thought to be responsible for the extraordinary high risk of HCC. Substantial progresses in the prevention of virusl-related hepatitis (screening of blood units, use of disposable sanitary tools, HBV vaccination) have been achieved in developed countries, but in the same areas, alcohol- and dysmetabolism-related HCCs are emerging problems which require specific interventions in terms of public health measures. In developing countries, economic constraints limit the development of any program for the prevention of viral hepatitis transmission (including health education campaigns, healthcare politics, primary prevention and the improvement of hygienic and sanitary conditions). When viral liver disease is established, only a minority of patients are treated worldwide and benefit a possible preventive effect of medical treatment on HCC development. Thus the real contribution of medical treatment to HCC prevention in patients with chronic viral hepatitis is small. Great efforts are needed to identify more effective medical measures for primary and secondary prevention of HCC.

Antiviral Agents↗

Legacy of implementing industrial health and safety in developing countries.

Aiming to develop public attention to the hindrance of national and international efforts on industrial health and safety, this paper explores some important issues, such as the reasons for the lack of motivation to implement necessary measures in developing countries. Examples are likewise given to show why working people are significantly exposed to a number of occupational problems that are reflected in a deterioration of their health, safety and well being. In lieu thereof, an introduction of health and safety is not itself a solution, if certain changes are not rationalised according to the local need. While health and safety intervention is concerned, then local need is of prime importance. If individual situation is not clearly outlined, then preventive and control measures can be treated as a de facto measure. Hence immediate attention, collaboration and co-operation is needed from all the concerned parties such as local government authorities, semi-government or private organisations and international communities for proper implementation of work regulations as well as industrial acts and rules in various workplaces in each of the developing countries.

Developing Countries↗

Quality specifications of clinical laboratory procedures: developing country needs.

In developing countries laboratory measurements are made in specimens of populations that are usually of different genetic origin and live in a different environment, under working conditions that differ from those of industrialized countries. The setting of quality specifications of laboratory measurements must take into account such differences to improve the quality of laboratory services in these countries. Industry and professional organizations should be aware of the differences, otherwise their recommendations may counteract efforts to improve laboratory services in developing countries.

Clinical Laboratory Techniques↗

The use of ultrasound in developing countries.

In many developing countries ultrasound services are either nonexistent or inadequate, although the diagnostic problems for which ultrasound is particularly suited are common in such countries. In view of this, the World Health Organization (WHO) has outlined the indications for diagnostic ultrasound together with the technical specifications for equipment. Where there are larger hospitals the basic ultrasound services should be complemented with the proposed general-purpose ultrasound scanner while at the level of major medical centres there will be need for a variety of special purpose ultrasonic units, e.g. for cardiac, intraluminal and interventional investigations. The usefulness of any ultrasound appliance depends to a great extent on the skill and experience of the operator. Therefore, WHO provides guidance on the training of general practitioner and expert sonographer that is necessary for proper implementations of this technology. In this review the authors discuss the various problems affecting the use of ultrasound in developing countries.

Developing Countries↗

Provision of medicines in a developing country.

In many developing countries the money spent on drugs could often be used more effectively to prevent disease. A large proportion of the drug budget of one developing country is spent on expensive proprietary preparations for use mainly in the larger hospitals, draining resources from health care in rural areas. A major factor in determining the country's expenditure on drugs is the promotional activities of pharmaceutical companies; the number of drug company representatives in the country is proportionately five times that in Britain. Many drugs are promoted for diseases for which they are not indicated and in which their use may be hazardous, and information on side-effects and contraindications is inadequate. Information supplied by drug firms to health workers in different countries must be standardised and the purchase and use of drugs in Third-World countries made more appropriate to their needs.

Costs and Cost Analysis↗

A simple and low-cost Internet-based teleconsultation system that could effectively solve the health care access problems in underserved areas of developing countries.

In many developing countries including Turkey, telemedicine systems are not in wide use due to the high cost and complexity of the required technology. Lack of these systems however has serious implications on patients who live in rural areas. The objective of this paper is to present a simple and economically affordable alternative to the current systems that would allow experts to easily access the medical data of their remote patients over the Internet. The system is developed in client-server architecture with a user-friendly graphical interface and various services are implemented as dynamic web pages based on PHP. The other key features of the system are its powerful security features and platform independency. An academic prototype is implemented and presented to the evaluation of a group of physicians. The results reveal that the system could find acceptance from the medical community and it could be an effective means of providing quality health care in developing countries.

Computer Graphics↗

Management of medical technology in developing countries.

To help developing countries to improve their medical use of physical technology, it is essential to study their difficulties and real needs. The greater severity of equipment problems in the third world, relative to the developed countries, indicates the important influence of an established technological culture. Strategies such as the training of technicians cannot succeed in the absence of this culture unless effective national policies to manage technology are implemented. The training of high-level staff in medical technology management must be a priority for international action. Below this level it is necessary to train engineering graduates, rather than technicians, to manage and maintain equipment.

Developing Countries↗

Who dies of what? A comparative analysis of mortality conditions in developed countries around 1987.

The developed countries are often viewed as being relatively homogeneous in terms of health conditions. This is not the case, however. Whilst the overall level of life expectancy in these countries (73.7 years) is well in excess of that observed in the majority of developing countries, there are nonetheless very substantial differences in health status among and between the developed countries. Female life expectancy is typically 6-8 years longer than that of males. The gap in life expectancy between Japan and some countries of Northern Europe, on the one hand, and the nations of Eastern Europe on the other, is of the same order of magnitude. Of the 11 million deaths reported in the developed countries each year, roughly 5.5 million or almost exactly 50% are attributable to cardiovascular diseases. Of these deaths, 2.4 million are coded to ischaemic heart disease and 1.5 million to stroke (cerebrovascular disease). Cancer (all forms) accounts for 2.3 million deaths (21%), 500,000 of which are due to lung cancer alone. External causes of death claim 750,000 lives each year in the developed countries, with suicide and motor-vehicle accidents each accounting for around 180,000 deaths. This pattern of mortality, when viewed in conjunction with the epidemiological evidence about the principal risk factors associated with these causes of death, strongly suggests that national health-for-all strategies must continue to emphasize individual health consciousness as the primary means of achieving national health goals.

Age Factors↗

Laboratory diagnosis of iron deficiency in a developing country, Pakistan.

In developing countries, such as Pakistan, laboratories do not routinely screen for iron deficiency unless the patient presents with symptoms of anaemia. Efforts to prevent the often serious consequences of iron depletion are hampered in developing countries by the expense and impracticality of routinely screening patients using bone marrow examination. Assays for serum iron concentrations, total iron-binding capacity or haemoglobin and examinations of blood films, although more practical, cannot detect the earliest stages of iron deficiency. Serum ferritin appears to be a sensitive, early indicator of iron deficiency and can be easily and relatively inexpensively determined using an immunoassay kit. In the present study, serum ferritin levels were determined using immunoassay and compared to blood films, serum iron levels and total iron-binding capacity values in 300 apparently healthy Pakistanis. In the early stages of iron deficiency, serum ferritin appeared to be a sensitive measure of iron depletion.

Adult↗

Animal biotechnology: applications and economic implications in developing countries.

In most developing countries, biotechnological applications relating to livestock need to be suitable for animal owners who are resource-poor small-scale operators who own little or no land and few animals. Livestock is becoming increasingly important to economic growth in developing countries and the application of biotechnology is largely dictated by commercial considerations and socio-economic goals. Using technology to support livestock production is an integral part of viable agriculture in multi-enterprise systems. Livestock are part of a fragile ecosystem and a rich source of animal biodiversity, as local species and breeds possess genes and traits of excellence. Molecular markers are increasingly being used to identify and select the particular genes that lead to these desirable traits and it is now possible to select superior germ plasm and disseminate it using artificial insemination, embryo transfer and other assisted reproductive technologies. These technologies have been used in the genetic improvement of livestock, particularly in cattle and buffaloes, and the economic returns are significant. However, morbidity and mortality among animals produced using assisted reproductive technologies lead to high economic losses, so the principal application of animal biotechnology at present is in the production of cheap and dependable diagnostic kits and vaccines. Several obstacles limit the application of biotechnology at present: there is a lack of infrastructure and insufficient manpower, so funding is needed if resource-poor farmers are to benefit from biotechnology.

Animal Husbandry↗

Urbanization patterns: European versus less developed countries.

This paper develops a model in which the interaction between transport costs, increasing returns to scale, and labor migration across sectors and regions creates a tendency for urban agglomeration. Demand from rural areas favors urban dispersion. European urbanization took place mainly in the 19th century, with higher costs of spatial interaction, weaker economies of scale, and a less-elastic supply of labor to the urban sector than in less developed countries (LDCs) today. These factors could help explain why primate cities dominate in LDCs, whereas a comparatively small share of urban population lives in Europe's largest cities.

Demography↗

Interventions for micronutrient deficiency control in developing countries: past, present and future.

There has been an evolution in our understanding of the causes of undernutrition and of the nutrition intervention programs that should be prioritized. This article discusses why nutrition programs have shifted their primary emphasis from control of protein deficiency, to energy deficiency, and now to micronutrient deficiencies. It has become recognized by the nutrition community that micronutrient malnutrition is very widespread, and is probably the main nutritional problem in the world. The most commonly used strategies for micronutrient deficiency control are supplementation and fortification, because they are cost-effective and to some extent, relatively easy to deliver. They have important limitations, however. Relatively little emphasis has been placed on food-based approaches to control micronutrient malnutrition. Evidence from several past studies, including the Nutrition Collaborative Research Support Program (N-CRSP), indicated a strong positive association between animal source food (ASF) intake, micronutrient status, and many human functions. This association motivated the intervention studies supported by the Global Livestock CRSP and described in this supplement, which found benefits of increasing ASF intake. In contrast to the common assumption that increasing consumption of ASF in poor communities is infeasible, and will only cause environmental problems, the articles in this supplement show the potential economic benefits of animal ownership in poor communities, and provide examples of innovative programs that have increased local production and consumption. Much more communication is needed among the nutrition, agriculture and development communities to achieve improved dietary quality for poor populations.

Animals↗

Health problems after travel to developing countries.

Travelers to developing countries participated in a follow-up study of the health risks associated with short (less than three months) visits to these nations. Travelers to the Greek or Canary Islands served as a control cohort. Participants completed a questionnaire to elicit information regarding pretravel vaccinations, malaria prophylaxis, and health problems during and after their journey. Relevant infections were confirmed by the respondent's personal physician. The questionnaire was completed by 10,524 travelers; the answer rate was 73.8%. After a visit to developing countries, 15% of the travelers reported health problems, 8% consulted a doctor, and 3% were unable to work for an average of 15 days. The incidence of infection per month abroad was as follows: giardiasis, 7/1,000; amebiasis, 4/1,000; hepatitis, 4/1,000; gonorrhea, 3/1,000; and malaria, helminthiases, or syphilis, less than 1/1,000. There were no cases of typhoid fever or cholera.

Adult↗

The tobacco problem: commercial profit versus health--the conflict of interests in developing countries.

As smoking gradually decreases in developed countries, the tobacco epidemic is overtaking developing countries, where the legislative controls and other measures, which in industrialised countries succeed in limiting tobacco use, either do not exist or are, at best, inadequate. Of particular concern is the penetration of developing countries by the transnational tobacco companies, who with aggressive promotional campaigns and the use of political and commercial pressures, open up markets to promote foreign cigarettes. The number of smokers in developing countries will inevitably increase, due to the rise in population, increased smoking among youth and women, lack of awareness of the harmfulness of tobacco, shortage of funding for tobacco control measures, and difficulties in implementing legislation. An appalling increase is predicted in disease, disability, and death from tobacco in developing countries. Developing countries must exercise their own public health responsibility and implement measures to reduce the growing tobacco epidemic. Health concerns in Western countries can assist by bringing these issues to public and government attention in order to ensure that transnational tobacco companies, at minimum, adhere to the same standards of product, marketing, promotion, and sales in developing countries as are required in their country of origin; that these tobacco companies should desist from lobbying and pressuring the governments of developing countries to prevent the passing and implementing of antitobacco measures; that the United States and UK governments desist from helping their tobacco companies with export activities; and that Western expertise in countering the tobacco epidemic be shared with developing countries so that the West becomes an exporter of health rather than of tobacco-related diseases.

Adolescent↗