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Body composition in adult growth hormone-deficient men, assessed by anthropometry and bioimpedance analysis.

Anthropometry and bioimpedance analysis (BIA) were used to assess body composition in 42 GH-deficient (GHD) adult males (mean age, 27.2 +/- 4.7 yr). During childhood, all patients had received GH treatment for a mean period of 8.4 +/- 3.8 yr. At the start of this study, GH therapy had been discontinued for a mean period of 7.5 +/- 4.5 yr. Eighteen patients had isolated GH deficiency (I-GHD). Twenty-four patients had multiple pituitary hormone deficiencies (M-PHD), substituted adequately. Compared to age- and sex-matched controls, the sum of skinfolds measured at 7 different sites was significantly higher in I-GHD and M-PHD patients [controls, 73.1 +/- 25.4 mm; I-GHD patients, 102.1 +/- 37.7 mm (P less than 0.001); M-PHD patients, 126.8 +/- 35.4 mm (P less than 0.001)]. The increase in sc fat deposition was most pronounced on the trunk, particularly in the breast and abdominal area. Total body muscle mass was significantly lower in GHD patients (P less than 0.001). In patients, body muscle mass and plasma somatomedin-C level were positively correlated (r = 0.43; P less than 0.005). Total body resistance measured by whole body BIA was significantly higher in the patient group and was negatively correlated with plasma somatomedin-C (r = -0.53; P less than 0.001). The high resistance values observed in GHD patients could only in part be explained by their lower lean body mass. The most important cause, however, was an increase in specific electrical resistance of the lean body mass (LBM), reflecting relative dehydration. We conclude that GH deficiency in adult males is associated with an increase in sc fat and a decrease in body muscle mass. In addition, there is a qualitative change in LBM. The BIA data indicate that in these patients, the hydration state of the LBM is lower than normal, due to a decrease in extracellular water.

Adipose Tissue↗

Facial anthropometry in cleft patients: a historical appraisal.

OBJECTIVE: To present a historical appraisal of the use of anthropological and cephalometrical facial soft tissue measurements in cleft patients. DESIGN: The McDowell Indexes and a Medline search were used to trace references up to 1999. Also, references listed with chapters and articles on facial clefts were searched for anthropometrical studies. Twenty-six retrieved articles and book chapters on soft tissue anthropometry and 12 cephalometric publications on soft tissue measurements on radiographs and plaster casts of cleft patients were reviewed. RESULTS AND CONCLUSIONS: Since 1931, the facial soft tissue appearance of cleft patients has been evaluated by means of anthropometric and cephalometric techniques. Not all of the older studies were performed in a statistically correct fashion. Many of the conclusions of the studies overlap despite differences in technique of assessment. Most studies demonstrate the deficient growth of the maxilla and the deformities of the facial profile in cleft patients.

Anthropometry↗

Relationship between absorption of radiolabeled soluble insulin, subcutaneous blood flow, and anthropometry.

OBJECTIVE: To evaluate the interrelationships between the rate of absorption of soluble insulin, SCBF, and anthropometry in normal subjects. RESEARCH DESIGN AND METHODS: In 12 normal men (age range 23-30 yr, BMI 18.2-41.3 kg/m2), simultaneous assessment of the absorption of 125I-labeled soluble insulin and SCBF (99mTc clearance) was performed, on separate study days, for the anterior abdominal wall, anterior midthigh, and the upper arm sites. Each site was examined in a randomized order on two separate occasions. Absorption of 125I-soluble insulin was determined by external monitoring of residual radioactivity levels at the injection site for 6 h postinjection. Residual radioactivity level-time curves, including the characteristic early phase of slow absorption of soluble insulin (the lag phase), were described using two- and three-parameter biexponential models. Anthropometric measurements included BMI, ultrasonic measurement of the subcutaneous adipose tissue layer, and caliper skin fold thickness at the anterior abdominal wall, biceps, triceps, anterior midthigh, and subscapular sites. RESULTS: A highly significant positive relationship was observed between the rate of absorption of 125I-soluble insulin and SCBF (rS = 0.44-0.52; P < 0.01-0.001). The duration of the lag phase was inversely correlated with SCBF (rS = 0.34 - 0.51; P < 0.01-0.001). Inverse relationships also were observed for the subjects' degree of adiposity with the rate of soluble insulin absorption (rS = -0.43(-)-0.71; P < 0.001) and SCBF (rS = -0.27(-)-0.62; P < 0.05-0.001). Significantly shorter lag phase was observed for the abdominal site compared with thigh and arm injection sites (P < 0.05-0.01). CONCLUSIONS: The rate of absorption of soluble insulin, including during the lag phase, is positively correlated with SCBF. Increasing adiposity prolongs the duration of the early lag phase and reduces the rate of absorption of soluble insulin and SCBF.

Absorption↗

Development of anthropometry-based equations for the estimation of the total body water in Koreans.

For developing race-specific anthropometry-based total body water (TBW) equations, we measured TBW using bioelectrical impedance analysis (TBW(BIA)) in 2,943 healthy Korean adults. Among them, 2,223 were used as a reference group. Two equations (TBW(K1) and TBW(K2)) were developed based on age, sex, height, and body weight. The adjusted R2 was 0.908 for TBW(K1) and 0.910 for TBW(K2). The remaining 720 subjects were used for the validation of our results. Watson (TBW(W)) and Hume-Weyers (TBW(H)) formulas were also used. In men, TBW(BIA) showed the highest correlation with TBW(H), followed by TBW(K1), TBW(K2) and TBW(W). TBW(K1) and TBW(K2) showed the lower root mean square errors (RMSE) and mean prediction errors (ME) than TBW(W) and TBW(H). On the Bland-Altman plot, the correlations between the differences and means were smaller for TBW(K2) than for TBW(K1). On the contrary, TBW(BIA) showed the highest correlation with TBW(W), followed by TBW(K2), TBW(K1), and TBW(H) in females. RMSE was smallest in TBW(W), followed by TBW(K2), TBW(K1) and TBW(H). ME was closest to zero for TBW(K2), followed by TBW(K1), TBW(W) and TBW(H). The correlation coefficients between the means and differences were highest in TBW(W), and lowest in TBW(K2). In conclusion, TBW(K2) provides better accuracy with a smaller bias than the TBW(W) or TBW(H) in males. TBW(K2) shows a similar accuracy, but with a smaller bias than TBW(W) in females.

Adult↗

Dietary nutrients and anthropometry of Dene/Métis and Yukon children.

OBJECTIVE: To describe nutrient intakes and anthropometry of 10-12-year-old Dene/Métis and Yukon children in the Canadian Arctic. STUDY DESIGN: 24 h-recall interviews (n = 222 interviews) were conducted on Canadian Dene/Métis and Yukon children in five communities during two seasons in 2000-2001; the children were measured for height and weight (n = 216). METHODS: Assessment of nutrient adequacy used Dietary Reference Intakes (DRIs) including cut-point procedures. Anthropometric measurements (height and weight) were assessed and body mass index (BMI) was compared to the 2000 CDC Growth Charts. RESULTS: Thirty-two percent of the children were above the 85th percentile of BMI-for-age. More than 50 percent of children were below the Estimated Average Requirement (EAR) for vitamins A and E, phosphorus and magnesium; mean intakes were below the Adequate Intake (AI) for vitamin D, calcium, dietary fiber, omega-6 fatty acids, and omega-3 fatty acids. Nutrients that were probably adequate for some gender/season groups were protein, carbohydrate, iron, copper, selenium, zinc, manganese, riboflavin and vitamins B6 and C. CONCLUSIONS: Excessive prevalence of overweight and inadequacy of some nutrients were observed among Dene/Métis and Yukon children, suggesting a necessity for dietary improvement. However, many nutrients were adequate, in some cases probably due to continued traditional food use.

Anthropometry↗

Anthropometry, lipid profile and dietary pattern of patients with chronic ischaemic heart disease.

The anthropometry, lipid profile and dietary characteristics of 114 patients with chronic ischaemic heart disease (IHD) were evaluated. There were 91 (80%) men and the mean age was 56 +/- 9 years. The body mass index was near normal (24.4 +/- 3.4), but the waist: hip ratio was high (0.94 +/- 0.06) suggesting central obesity. This was well in accordance of the step II recommendations of the NCEP guidelines as regards their caloric intake and its break-up in terms of carbohydrate, protein and fat (including saturated, mono-unsaturated and poly-unsaturated fatty acids) content. Their daily cholesterol intake (31 +/- 32 mg/day, range 4-180) was very low. The total cholesterol (212 +/- 37 mg%) was marginally elevated, HDL cholesterol (33 +/- 7.5 mg%) was low, LDL cholesterol (148 +/- 39 mg%) was high and the total: HDL ratio (6.8 +/- 2.0) was significantly abnormal. The serum triglyceride level (154 +/- 68 mg%) was on the higher side of normal. These observations give further credence to the recently evolving view that there are different and hitherto unrecognised risk factors of IHD in Indians, who seem to have the highest incidence of IHD amongst all ethnic groups of the world despite consuming a diet low in fat and cholesterol content.

Adult↗

Is chronic hypoxemia in patients with chronic obstructive pulmonary disease associated with more marked nutritional deficiency? A study of the fat-free mass evaluated by anthropometry and bioelectrical impedance methods.

In order to determine wheter blood gases abnormalities, specially hypoxemia, are associated with more marked changes in fat-free mass in patients with chronic obstructive pulmonary disease (CPOD), nutritional assessment was performed on 16 normoxemic (PaO2 > 55 mm Hg) and 16 hypoxemic (PaO2 < 55 mm Hg) COPD patients in stable clinical condition. Body weight was expressed as percentage of the ideal body weight. Fat-free mass was estimated by anthropometry (FFM-Anthr) and by bioelectrical impedance (FFM-BI). Handgrip-strength was assessed as a measure of peripheral skeletal muscle strength. Patients were age-matched and presented similar degree of airway obstruction. Malnutrition, defined as body weight less than 90% of the ideal, was observed in 19% of the normoxemic patients and in 25% of the hypoxemic patients (p>0,05). FFM values in hypoxemic patients, estimated by both methods, were not different from those observed in normoxemic patients. No significant difference was observed on handgrip values between the two groups. No correlation was found between nutritional indices and pulmonary function and gases exchange parameters. FFM correlated positively with values of peripheral muscle function in normoxemic and hypoxemic patients. These data add further evidence to the hypothesis that hypoxemia is not a primary cause of the nutritional deficiency observed in COPD patients.

Aged↗

[Body composition in chronic obstructive lung patients. Comparison of bioelectric impedance and anthropometry].

Malnutrition is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). Body weight is not a reliable evaluation criterium. Body composition which is more useful can be determined routinely using 2 techniques: skinfold thickness anthropometry (Ant) and bioelectrical impedance analysis (BIA). The validity of this last technique has not been demonstrated in patients with COPD. Fat-free mass (FFM) in 58 patients (51 men, 7 women) with stable COPD (FEV1 < 50% of predicted value) was assessed using the 4-skinfold-thickness method (Ant) and BIA (Imp). Statistical analysis included correlation analysis, intraclass correlation coefficient, and the Bland and Altman analysis. Imp-FFM and Ant-FFM correlated well (r = 0.920; p < 0.0001). Intraclass correlation coefficient was high (rI = 0.9065). However, the values were scattered and there was a systematic bias (significant linear regression between the difference in estimates obtained by the 2 methods and the means). As anthropometric measurements are not reliable in the elderly patients, our results suggest that BIA could be a useful tool to determine FFM in patients with COPD. Its validity still has to be tested against a reference method.

Adipose Tissue↗

Dietary intake and anthropometry of Korean elderly people: a literature review.

The health status of elderly people is an important issue in Korea due to the expansion of the elderly population. However, data on their nutritional status are limited. This review aims to give an overview of the dietary intake and anthropometry of Korean elderly people based on studies published, mainly in local journals in Korea. In total 18 studies were reviewed. Mean calcium and vitamin A intakes were inadequate, namely less than 67% of the Korean recommended daily allowances, in all groups of Korean elderly people. The intake of both nutrients was lower in urban elderly with a low income and in rural elderly (200-496 g/day of calcium and 117-281 retinol equivalents/day). In particular, "low income" urban elderly people had a low energy intake (less than 5300 kJ/day) with an inadequate intake of iron, thiamin, riboflavin and niacin in addition to calcium and vitamin A. In urban areas underweight (body mass index <20 kg/m2) occurred in 7-31% of "all income" groups, whereas it occurred in 15-42% of "low income" groups. Rural elderly people showed a higher proportion of underweight (37% for men and 38% for women) as well as the lowest body mass index (21.0 kg/m2 for men and 21.3 kg/m2 for women). In conclusion, an inadequate intake of several micronutrients in old age, mostly calcium and vitamin A, is a matter of concern in Korea. This was observed most frequently in elderly people with a low income. In this group an inadequate intake of micronutrients is likely to be caused by a low energy intake.

Adolescent↗

Pulmonary functions in patients with type 2 diabetes mellitus & correlation with anthropometry & microvascular complications.

BACKGROUND & OBJECTIVES: The purpose of this study was to evaluate pulmonary functions including respiratory muscle strength in patients with type 2 diabetes mellitus (T2DM) and to determine their correlations with anthropometric profile, glycaemic control, and microangiopathic diabetic complications. METHODS: Twenty nine patients with T2DM and 11 healthy control subjects were divided into the following three groups; (i) T2DM patients with any or a combination of microangiopathy(ies) (retinopathy, nephropathy, and peripheral neuropathy) (group 1, n=12); (ii) T2DM patients without any complications (group 2, n = 17); and (iii) a healthy control group (group 3, n=11). All patients were assessed with anthropometry, glycosylated haemoglobin (HbA1C), and lipid profile. Pulmonary functions were measured by spirometry. Pulmonary diffusion capacity for carbon monoxide (DLco) was measured by the steady state method. The presence of diabetic nephropathy was determined by 24 h protein excretion. RESULTS: A significant reduction of DLco was observed in group 1 (P<0.001), as compared to the other groups. There were no differences among the three groups for other pulmonary functions; forced vital capacity, forced expired volume in one second, peak expiratory flow rate, and maximal static inspiratory and expiratory pressures. Significant correlations were observed between DLco and the following parameters in group 1; HbA1c (r=0.62, P<0.05), total cholesterol level (r = -0.44, P<0.05) and creatinine clearance (r=0.42, P<0.05). INTERPRETATION & CONCLUSION: The present study shows that the impairment of pulmonary diffusion capacity for carbon monoxide was common in T2DM Asian Indian patients having microangiopathy. Pathophysiologically, it could be related to glycaemic control or dyslipidaemia. Correlation of % BF with DLCo needs to be explored further.

Adult↗

[Comparative analysis of body composition assessment methods in healthy men and in chronic obstructive pulmonary disease patients: anthropometry, bioelectrical impedance and dual-energy X-ray absorptiometry].

UNLABELLED: The aim of this study was to examine the agreement between the results of body fat (BF and BF%), fat-free mass (FFM) and FFM index (FFMI= FFM/height2) as estimated by skinfold anthropometry (ANT), bioelectrical impedance (BIA) and dual-energy X-ray absorptiometry (DXA) in two groups of men (> or = 50 y), one comprising healthy individuals (n=23) and the other, patients with chronic obstructive pulmonary disease (COPD) (n=24). Comparisons between body composition techniques were done by repeated measures ANOVA; the Bland & Altman procedure was used to analyse agreement. RESULTS AND CONCLUSIONS: 1) comparison between healthy and COPD groups showed significant differences between all studied variables; 2) in the healthy group, values for BF, BF%, FFM and FFMI were not significantly different when BIA or ANT was compared to DXA; however, in COPD, values for BF and BF% were significantly higher and for FFM and FFMI significantly lower when BIA was compared to DXA; in contrast, no differences were shown between values for these variables when ANT was compared with DXA; 3) Bland & Altman test, in both groups, showed no agreement between BIA and DXA and between ANT and DXA; it was also shown that body fat was overestimated and fat free mass underestimated by BIA in relation to DXA.

Absorptiometry, Photon↗

Anthropometry and somatotype of competitive female figure skaters 11-22 years. Variation by competitive level and discipline.

AIM: Variation in anthropometric characteristics and somatotype of female figure skaters by level of competition and discipline was examined. METHODS EXPERIMENTAL DESIGN: ANCOVA with age as the covariate was used to compare the anthropometry of skaters by level (test stream, pre-elite, elite) and discipline (free, dance, pair), while MANCOVA was used to compare somatotype. SETTING: purposive sampling reflecting the skating population by level and discipline was used to recruit skaters in 4 American, and 7 Canadian figure skating clubs. PARTICIPANTS: a total of 161 competitive female figure skaters 11-22 years of age (15.7+/-2.4 years) comprised the sample. MEASURES: a battery of 15 anthropometric dimensions was taken on each skater. Several dimensions, ratios and Heath-Carter somatotypes were derived. RESULTS: Test skaters are heavier and generally larger than pre-elite skaters. Test stream skaters also have larger limb circumferences, estimated calf and arm musculature, and a thicker sum of skinfolds, and are more endomorphic than pre-elite skaters. Elite skaters are more mesomorphic than pre-elite skaters. The sitting height/stature (SH/ST) ratio is significantly lower in pre-elite skaters, while elite and test stream skaters do not differ in this indicator of proportions. Free skaters are taller and heavier; have a higher body mass index (BMI), limb circumferences and sum of skinfolds; and proportionally shorter legs than dancers and pair skaters. Free skaters, dancers and pair skaters, however, do not differ in somatotype. CONCLUSIONS: The results suggest that figure skating favors lightness, leanness, higher mesomorphy and lower endomorphy at more elite levels. Shortness, leanness and linearity of physique appear to be selective factors associated with specialization in dance and pair skating.

Adolescent↗

[Anthropometry and female breast cancer: a prospective cohort study in urban Shanghai].

OBJECTIVE: To investigate the association between anthropometry and risk of breast cancer among pre-and post-menopausal women in urban Shanghai. METHODS: A total of 73 461 female residents aged 40 to 70 years in urban Shanghai were recruited in a prospective cohort study (the Shanghai women's health study) during 1997 through 2000, and were actively followed up biennially. During mean follow-up period of 5.66 years, 432 incident cases of breast cancer were identified in the cohort. Cox regression model was used to estimate the adjusted relative risks (RRs) and 95% confidence intervals (CIs). RESULTS: After adjustment for some potential confounding factors, baseline weight, body mass index(BMI), waist-to-hip ratio(WHR) and weight gain since age 20 were positively associated with the increased risk of breast cancer among postmenopausal women. The positive association between height and breast cancer was found among premenopausal women. Among them, those with height taller than 161 cm at age 20 experienced 1.84 fold increased risk (95% CI: 1.30-2.61) of breast cancer compared to their counterpart with height shorter than 157.1 cm. Women who were either much heavier or lighter than average at age 20 were at reduced risk. Further analyses mutually adjusted for BMI and WHR did not substantially alter the positive association for both BMI and WHR. After further adjustment for BMI, weight gain since age 20 was significantly associated to an increased risk for postmenopausal breast cancer (RR = 1.61, 95% CI: 1.09-2.37). CONCLUSIONS: Weight gain and central obesity seemed to be strong predictors for the risk of breast cancer among postmenopausal women. Controlling weight and decreasing fat around waist were effective means to prevent postmenopausal breast cancer and height might serve as a risk factor for premenopausal breast cancer.

Adult↗

Measurement precision and reliability in craniofacial anthropometry: implications and suggestions for clinical applications.

Craniofacial anthropometry has become an important tool used by both clinical geneticists and reconstructive surgeons. Yet little attention has been paid to the potentially serious problem of measurement error. This paper examines intra-observer measurement error and precision (also called repeatability or reliability) for 52 commonly used anthropometric variables of the head and face. Two factors proved critical to reliability: magnitude of the measurement in question and the degree to which its constituant landmarks could be readily identified. Thus, all of the measurement variables with means above 10 cm proved to have good or excellent reliability. In contrast measurement variables with means below 10 cm were more likely to have poor reliability. This trend was especially evident in variables with means of 6 cm or less where 18 of the 20 variables in this range had poor reliability. The least reliable variables were those like philtrum breadth, columella breadth, and nasal root breadth that combine small magnitude with difficult to define landmarks. While these results suggest that it may be prudent to avoid using craniofacial variables with small dimensions this may be neither practical nor desirable. In such cases repeat measurements may be the best means for optimizing reliability.

Adult↗

Maternal anthropometry for prediction of pregnancy outcomes: memorandum from a USAID/WHO/PAHO/MotherCare meeting.

The meeting discussed two main areas concerning maternal anthropometry in developing countries: (1) how various anthropometric indicators can be best utilized for assessing and monitoring the nutritional status of women at different times in their reproductive lives, and (2) the predictive value of various anthropometric indicators for identifying benefit or risk for maternal and perinatal/neonatal health and nutritional outcomes of pregnancy. The indicators discussed were prepregnancy weight, height, weight gain in pregnancy, arm circumference, weight-for-height and body mass index (weight (kg)/height (m)2). Some 50 experts reached consensus on the tools for assessing maternal nutritional status for widespread field application in developing countries, and on priority research needs. This Memorandum summarizes the general recommendations which have important and immediate field applications, as well as priority research issues related to specific indicators.

Anthropometry↗

Relation between body composition, anthropometry, and glucose tolerance.

Based upon the results of a 75 g oral glucose tolerance test, 305 subjects (157 men and 148 women), who were admitted to the National Cheng Kung University Hospital for health check-up, were divided into diabetic (n = 47, 25 men and 22 women), impaired glucose tolerance (IGT) (n = 53, 27 men and 26 women) and normal (n = 205, 105 men an 100 women) groups. All diabetics were of non-insulin-dependent diabetics. Body composition and anthropometries including body mass index (BMI), thickness of triceps skinfold (TSF), arm muscle circumference (AMC), and blood pressure were compared among these three groups. Body composition (percentage of fat, lean mass and total body water) was significantly correlated to BMI, TSF, AMC, blood pressure, blood glucose, hemoglobin Alc (HbAlc) and cholesterol. BMI was significantly correlated to blood pressure, blood glucose, HbAlc, triglyceride and serum glutamic pyruvic transaminase (SGPT) levels. TSF and AMC were not correlated to blood pressure, blood glucose, HbAlc or blood lipids. However, in defining adiposity, TSF seems more sensitive than BMI. The data of the IGT group did not show a significant difference from those of the normal group except for a higher systolic pressure and a 2-hour plasma glucose level after a 75 g oral glucose loading. The diabetic group showed significantly higher BMI, systolic pressure, triglyceride, and SGPT levels than both the IGT and normal groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Bioelectrical impedance, anthropometry and body composition in stunted and non-stunted children.

Bioelectrical impedance (BIA) and anthropometric measurements were taken of 129 stunted and 32 non-stunted children aged 9-24 months in Kingston, Jamaica. The reliability of BIA in such young children was examined and the relationships between impedance and anthropometry were determined. The stunted children had significantly lower body mass index (BMI) and smaller triceps skinfolds than the non-stunted children, suggesting differences in body composition between the groups. Resistance was significantly higher in the stunted children than the non-stunted children and nutritional group (stunted or non-stunted) contributed significantly to the variance in resistance after controlling for length, weight, mid-upper arm circumference, triceps and subscapular skinfolds, age and sex. This suggests that there were differences in body composition and/or body shape between the groups beyond that measured by the anthropometric indices used. Total body water (TBW) was estimated using an equation for Jamaican children of comparable age. As a percentage of body weight the TBW estimates were the same for the two groups, a finding which is inconsistent with the anthropometric data.

Anthropometry↗

[Determination of body fat by means of densitometry and anthropometry in children 6 to 10 years of age].

The authors have studied the body composition in a group of 36 boys from 7 to 10 years old, through densitometry and anthropometry. They have found significant correlations between the percentage of fat, got by densitometry and some anthropometric indices: Quetelet index (r = 0.79), sum of 4 skinfolds (r = 0.78) and logarithm of the sum of 4 skinfolds (r = 0.80). After a multiple regression analysis, they got equations which permit you to calculate the percentage of fat, using several anthropometric parameters with a 10% of error. They bring two nomograms which facilitate the estimation of body fat. They compare the results obtained with the ones described by others authors and suggest the need to extend this study to boys with other ages as well as to girls.

Anthropometry↗