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PubMed · 9720263

Structure-based drug design.

L M Amzel
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Abstract

Most of the techniques used in structure-based drug design have experienced significant improvements in the past few years, resulting in a marked enhancement of the speed and the efficacy of this approach. At the same time, it was thought that the future of drug design lay in strategies involving solely combinatorial chemistry. It is becoming evident, however, that the development of future drugs will use a combination of methods that will contain a major component of structure-based design.

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Databases, FactualDrug DesignMembrane ProteinsModels, BiologicalProtein BindingProteinsJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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L M Amzel. 1998. Structure-based drug design.. https://doi.org/10.1016/s0958-1669(98)80009-8

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