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PubMed · 9523072

Surfactant. Evolving issues.

J Kattwinkel
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Abstract

Understanding surfactant composition, function, and therapeutic usefulness has increased exponentially over the last 40 years. This article reviews the history and current understanding of surfactants, composition and comparisons of surfactants, method and timing of surfactant administration, dosage and retreatments, and the use of surfactants in conditions other than respiratory distress syndrome.

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Gestational AgeHumansInfant, NewbornInfant, PrematureMeconium Aspiration SyndromePulmonary SurfactantsRespiratory Distress SyndromeRespiratory Distress Syndrome, NewbornTime FactorsJournal ArticleReview

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J Kattwinkel. 1998. Surfactant. Evolving issues.. https://pubmed.ncbi.nlm.nih.gov/9523072/

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[TSH, FT4 and T3T evaluation in normal and preterm hospitalized newborns].

UNLABELLED: Thyroid hormones are essential for foetus and newborn development. Preterm newborns present low levels for thyroid hormones. These low levels are related with disorder in psychomotor and neurological development. In the literature, several studies concerning newborns treated with thyroid hormone have been realized in different conditions; however, there is no consensus about preterm newborn supplementation benefit. OBJECTIVE: The aim of the study was to defined hormonal values used for normal and preterm newborns. MATERIAL AND METHODS: We reported TSH, T3T and T4L levels for 195 normal or preterm newborns, eutrophic or small for gestational age (SGA). RESULTS: A positive correlation was found between hormonal level and gestational age. This work allowed us to define a threshold for preterm newborn according to their gestational age. CONCLUSION: Owing to lack of consensus, those values are useful for clinical and biological follow-up of thyroid function for newborns at risk (SGA and preterm before 32 weeks) during the first year of life. Finally, it would be interesting to study systematic supplementation of thyroid hormone for those infants in a prospective study.

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