Origin DNA-binding proteins.

A M Edwards; A Bochkarev; L Frappier

doi:10.1016/s0959-440x(98)80009-2

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PubMed · 9519296

Origin DNA-binding proteins.

A M Edwards·A Bochkarev·L Frappier

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Abstract

The first step in DNA replication involves the recognition of origin DNA sequences by origin-binding proteins. The three-dimensional structures of three different origin DNA-binding proteins have recently been solved. These proteins form a structural class distinct from other DNA-binding proteins. One of the origin-binding proteins, Epstein-Barr virus nuclear antigen 1, most likely has two modes of DNA binding; the sequential use of these modes may be important for the initiation of DNA replication.

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Antigens, Polyomavirus Transforming DNA Replication DNA, Viral DNA-Binding Proteins Dimerization Epstein-Barr Virus Nuclear Antigens Herpesvirus 4, Human Models, Molecular Protein Conformation Replication Origin Sequence Homology Viral Proteins Journal Article Review

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A M Edwards, A Bochkarev, L Frappier. 1998. Origin DNA-binding proteins.. https://doi.org/10.1016/s0959-440x(98)80009-2

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