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PubMed · 9500895

Gradient- and sensitivity-enhanced TOCSY experiments.

K E Kövér·D Uhrín·V J Hruby
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Abstract

A pulsed field gradient version of the sensitivity-enhanced 2D TOCSY experiment is proposed which yields high-quality spectra with improved sensitivity and a minimum of two scans per t1 increment. For rapid acquisition of 1D TOCSY spectra, the 1D DPFGSE-TOCSY experiment was modified to include phase-encoded multiple-selective excitation followed by a simple spectral editing. Combination of these two building blocks is used in a sensitivity-enhanced 2D analog of the 3D TOCSY-TOCSY experiment which provides an efficient tool for resolving severely overlapped signals of oligomers in short experimental time.

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Analgesics, OpioidArtifactsImage EnhancementImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyOligopeptidesSensitivity and SpecificitySoftwareComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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K E Kövér, D Uhrín, V J Hruby. 1998. Gradient- and sensitivity-enhanced TOCSY experiments.. https://doi.org/10.1006/jmre.1997.1309

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