PubMed · 9411977
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H D Schrøder. 1997-11-03. [Dissection, autopsy, postmortem examination].. https://pubmed.ncbi.nlm.nih.gov/9411977/
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This paper describes structural characterization by NMR, MS and degradative studies of mucin glycans from normal human descending colon obtained freshly at autopsy. The saccharides were mainly based on core 3 (GlcNAcbeta1-3GalNAc). Among the terminal saccharide determinants Sd(a)/Cad-antigen-like structures were prominent, and Lewis x, sialyl Lewis x and sulphated Lewis x were found as minor components, whereas blood group H and A antigenic determinants were absent. The saccharides were markedly different from those of mucins from colon cancers or colon cancer cell lines analysed so far, in which cores 1 and 2 are prominent features, and in which various other terminal determinants have been found, but not Sd(a)/Cad.
The role of the attending physician and the district medical examiner in the case of a natural or unnatural death is subject to a number of legal regulations. The different parts of a postmortem examination, the conditions for the issue of a death certificate, the term 'attending physician', and the position and duties of the district medical examiner are not, however, unequivocally specified in Dutch law. This gives rise to frequent misunderstandings.
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