Extradural aneurysms.

J D Barr; B P Holmes; K A Edgar

Home/Archive/PubMed

PubMed · 9336499

Extradural aneurysms.

J D Barr·B P Holmes·K A Edgar

View original source ↗Export metadata ↓

Abstract

Extradural aneurysms have distinct characteristics from their intradural counterparts. Most extradural aneurysms cannot be treated by direct surgical exposure and clip ligation or by direct endovascular means without parent vessel sacrifice. Arterial occlusion with or without bypass grafting remains the traditional treatment. Controversy about the "best" or "proper" technique of arterial balloon test occlusion is rivaled only by that of the necessity for bypass grafting when apparent tolerance for arterial occlusion has been demonstrated.

Explore related subjects

Aneurysm Carotid Artery Diseases Carotid Artery, Common Carotid Artery, Internal Cerebrovascular Circulation Collateral Circulation Dura Mater Embolization, Therapeutic Humans Ligation Regional Blood Flow Saphenous Vein Journal Article Review

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

J D Barr, B P Holmes, K A Edgar. 1997. Extradural aneurysms.. https://pubmed.ncbi.nlm.nih.gov/9336499/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2026

Mechanistic insights into Claudin-14 dysfunction implicated in veins of Galen malformation.

Claudin-14 (CLDN14) is a key component of tight junctions (TJs) critical for maintaining paracellular barrier function. Variants of CLDN14 have been linked to Vein of Galen malformations (VOGMs), a rare cerebrovascular disorder; however, the molecular mechanisms underlying their pathogenicity remain unknown. Here, we investigate the mechanistic effects of two VOGM-associated mutations, A113P and V143M, using reinforcement-learning driven enhanced sampling molecular dynamics simulations combined with DiffNets-based deep learning and independent trajectory-wide structural analyses. Our analysis reveals that A113P induces broader structural disruption of CLDN14, perturbing paracellular sealing, pore symmetry, and inter-protomer communication, whereas V143M induces structural rearrangements centred around TM3 and the TM3-ECL2 region. In both cases, mutation-specific alterations are observed in structural stability and interfacial organization across oligomeric assemblies. Notably, these effects are qualitatively consistent across different modelled architectures, despite variability in local responses. In the absence of experimentally resolved structures, the structural perturbations reported here provide a mechanistic understanding of how VOGM-associated variants may influence CLDN14 structure and dynamics.

Aneurysm↗

PubMed2001

Covered stent for renal artery aneurysm.

This is a case of a 51-year-old female with difficult-to-control hypertension and a 3-cm renal artery aneurysm. Successful exclusion of this was performed using a prefabricated stent graft. To our knowledge, this is the first report on the use of a prefabricated covered stent for this indication.

Aneurysm↗

PubMed2001

Idiopathic main pulmonary artery aneurysm.

Main pulmonary artery aneurysms with no underlying pathology are very rare, and the role of surgery in this entity is not well defined. We report our experience of one case.

Aneurysm↗