PubMed · 9172544
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K Tanaka, M Toriumi, S Itoh, Y Ogino. 1997. [ACTH test].. https://pubmed.ncbi.nlm.nih.gov/9172544/
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Organ specific autoimmune diseases are predominantly diseases of the endocrine glands and involve amongst others the thyroid (Hashimoto's disease, primary myxoedema, Graves' disease), the islets of Langerhans (type I diabetes mellitus) and the adrenals (Addison's disease). Over the past fifty years the knowledge on the pathogenesis of these diseases has considerably increased, leading to a large number of newly developed diagnostic tools, particularly determination of autoantibodies. Most of these autoimmune diseases have a (long) subclinical latency period. During this latency period a reliable prediction of later clinical manifestation is feasible. Preventive interventions during the latency period to correct underlying abnormalities of the target endocrine gland and/or the immune system are currently being tested in experimental animal models.
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