PubMed · 9047980
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O Aizawa, S Mochizuki, M Kawakami. 1996. [Systemic necrotizing angitis, hypersensitivity vasculitis].. https://pubmed.ncbi.nlm.nih.gov/9047980/
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This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later.
Apart from some inherited forms, polyneuropathy is a disorder secondary to systemic diseases. The symptoms of chronic polyneuropathy usually appear some years after the main disease has been diagnosed. However, the acute-subacute form can be the first manifestation of a systemic disease, when its typical clinical features are still absent. The diagnosis of polyneuropathy is based on clinical symptoms and electrophysiologic studies, and it also could be supported by spinal fluid examination and peripheral nerve biopsy. The authors report here a case presenting as Churg-Strauss syndrome complicated with subacute axonal polyneuropathy and eosinophilia characteristic of the disease. Although Churg-Strauss syndrome is rare, it is important to recognise it, because remission depends on immunosuppressive therapy introduced in the early stage.
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