Replaceable polymers in DNA sequencing by capillary electrophoresis.

M A Quesada

doi:10.1016/s0958-1669(97)80162-0

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Replaceable polymers in DNA sequencing by capillary electrophoresis.

M A Quesada

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Abstract

Much progress has been made in the development of replaceable sieving polymers and capillary coatings for high-performance DNA sequencing by capillary electrophoresis. Several studies of parameters that affect resolution, read length and reproducibility have begun to reveal the physical mechanisms acting on single-stranded DNA during electrophoresis through semidilute polymer solutions. Recently developed electro-osmosis-inhibiting matrix polymers have simplified the process of coating capillaries, facilitating the automation of high-throughput parallel systems for large-scale sequencing.

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Biotechnology Electrophoresis, Capillary Evaluation Studies as Topic Models, Chemical Molecular Structure Polymers Sequence Analysis, DNA Solutions Comparative Study Journal Article Review

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M A Quesada. 1997. Replaceable polymers in DNA sequencing by capillary electrophoresis.. https://doi.org/10.1016/s0958-1669(97)80162-0

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