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PubMed · 8807822

Sonic hedgehog: making the gradient.

D A Bumcrot·A P McMahon
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Abstract

The amino-terminal peptide of Sonic hedgehog is a cell-tethered molecule, which nevertheless seems to provide a developmental signal that acts at a distance and has different effects depending on its concentration. Recent structural data suggest that zinc-dependent proteolysis may somehow be involved in Sonic hedgehog's function.

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D A Bumcrot, A P McMahon. 1996. Sonic hedgehog: making the gradient.. https://doi.org/10.1016/s1074-5521(96)90077-0

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