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PubMed · 879140

Abnormal liver function in chronic hypervitaminosis A.

G C Farrell·P S Bhathal·L W Powell
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Abstract

A case of chronic hypervitaminosis A is reported in a 57-year-old woman who took vitamin preparations for alopecia. Liver biopsy of the patient showed both an increase in the number and size of fat-storing cells on light microscopy and rapidly fading green autofluorescence of vitamin A. Electron microscopy confirmed the presence of engorged fat-storing cells in the space of Disse and minor toxic changes in hepatocytes. This case illustrates the early hepatic changes of chronic hypervitaminosis A and indicates a need for restriction of sales of vitamin preparations.

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Biopsy, NeedleChemical and Drug Induced Liver InjuryChronic DiseaseFemaleHumansLiverLiver Function TestsMiddle AgedVitamin ACase ReportsJournal Article

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BibTeXRIS

G C Farrell, P S Bhathal, L W Powell. 1977. Abnormal liver function in chronic hypervitaminosis A.. https://doi.org/10.1007/bf01078355

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Biopsy, Needle↗