Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 879086

Urinary chemistry. A new CAP program.

G C Glenn·T K Hathaway
View original source ↗Export metadata ↓

Abstract

A pilot survey program for urinary chemistry was implemented by the College of American Pathologists during the year 1976. The nine analytes selected for the program were amylase, calcium, phosphorus, sodium, potassium, creatinine, osmolality, 17-ketosteroids and total protein. Data obtained from more than 230 enrolled laboratories indicate deficiencies in assay performance for amylase, 17-ketosteroids and total protein as measured by consensus evaluation. Acceptable performance was apparent for the remaining analytes.

Explore related subjects

17-KetosteroidsAmylasesCalciumClinical Laboratory TechniquesCreatinineHumansMethodsOsmolar ConcentrationPhosphorusPotassiumProteinuriaQuality ControlSodiumUnited StatesUrineJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

G C Glenn, T K Hathaway. 1977. Urinary chemistry. A new CAP program.. https://pubmed.ncbi.nlm.nih.gov/879086/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

[Surgical treatment of polycystic ovary syndrome. B. Postoperative examinations].

After the wedge resection of the ovaries the authors obtained the normal menses in 100%, the reduction of total testosterone in blood of 41.8% and of 17-KS in urine of 20%, an increase of fertility of 62.5% and in hirsutism a correction only of 12%, the stopping of 12% and no correction of 76%. The authors conclude that the cause of the healing or of the correction is placed in the resection of 3/4 of the changed ovaries with cysts follicles with distinct thecal layer what is accompanied by the reduction of testosterone on average of 41.8%. On contrary a weak correction in hirsutism has the explanation that the existent hirsutism is supported even by the normal level of testosterone in organism.

17-Ketosteroids↗
PubMed1992

[Hormonal correlations in stomach cancer patients].

The urinary excretion of andro- and glucocorticoidogenesis metabolites was studied in 60 patients with gastric cancer (stages II-III and IV). The androgenous activity showed a significant decrease that was manifested in a reduced excretion of 17-ketosteroids (17-KS) and their androgenicity index (AI). With advance of the disease stage androsterone/ethiocholanolon ratio reduced and became less than 1 in most patients. In patients with stage II-III gastric cancer there occurred a significant increase of the glucocorticoid function of the adrenals and a decrease in patients with stage IV cancer. Comparison with the androgenous activity revealed both an absolute and a relative androgenic insufficiency in patients with gastric cancer. It is suggested that reduced production of androgens effects favourably the catabolic manifestation of the effect of glucocorticoids. Drug-stimulated increase of the production of androgens in the body of patients with gastric cancer is desired.

17-Ketosteroids↗