From DNA sequence to biological function.

S G Oliver

doi:10.1038/379597a0

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PubMed · 8628394

From DNA sequence to biological function.

S G Oliver

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Abstract

Genome sequencing is leading to the discovery of new genes at a rate 50-100 times greater than that achieved by classical genetics, but the biological function of almost half of these genes is completely unknown. In order fully to exploit genome sequence data, a systematic approach to the discovery of gene function is required. Possible strategies are discussed here in the context of functional analysis in the yeast Saccharomyces cerevisiae, a model eukaryote whose genome sequence will soon be completed.

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Base Sequence DNA, Fungal Genes, Fungal Genome Humans Molecular Sequence Data Open Reading Frames Phenotype Saccharomyces cerevisiae Sequence Homology, Nucleic Acid Journal Article Research Support, Non-U.S. Gov't

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S G Oliver. 1996-02-15. From DNA sequence to biological function.. https://doi.org/10.1038/379597a0

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