Specificity and effector-target interaction.

M Takasugi

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PubMed · 86161

Specificity and effector-target interaction.

M Takasugi

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Abstract

When effector cells were tested on a number of target cells, the most obvious effect observed was a nonselective cytotoxicity that is now known as natural cell-mediated cytotoxicity. The apparent nonselectivity was a result of specific cytotoxic activity against many different antigens on target cells. This specificity was demonstrated in the cross-competition assay in which target cells sharing common antigens selectively inhibited natural cytotoxicity.

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Cross Reactions Cytotoxicity Tests, Immunologic Epitopes Humans Immunity, Cellular Immunity, Innate In Vitro Techniques Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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M Takasugi. 1978. Specificity and effector-target interaction.. https://pubmed.ncbi.nlm.nih.gov/86161/

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