Phage display: protein engineering by directed evolution.

K T O'Neil; R H Hoess

doi:10.1016/0959-440x(95)80027-1

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Phage display: protein engineering by directed evolution.

K T O'Neil·R H Hoess

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Abstract

Phage display of proteins has become an important tool for protein engineering. Over the past year, the versatility of the technology has expanded to include the development of DNA-binding proteins with novel specificities, energetics of protein folding and directed evolution of antibodies. In addition, display of expressed cDNA libraries opens an exciting opportunity for studying protein-protein interactions.

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Antibodies Bacteriophages Catalysis DNA-Binding Proteins Directed Molecular Evolution Enzymes Humans Protein Engineering Protein Folding Recombinant Proteins Journal Article Review

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K T O'Neil, R H Hoess. 1995. Phage display: protein engineering by directed evolution.. https://doi.org/10.1016/0959-440x(95)80027-1

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