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PubMed · 836084

Collagen breakdown and nitrogen dioxide inhalation.

D V Hatton·C S Leach·A E Nicogossian
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Abstract

Measurements of urinary hydroxylysine glycosides indicate that considerable collagen degradation occurred during the reentry into the earth's atmosphere of the American astronauts of the Apollo-Soyuz mission. Since the crew accidentally inhaled nitrogen dioxide, a recognized pulmonary irritant, and showed clinical and roentgenographic signs of diffuse chemical pneumonitis, it is likely that collagen degradation occurred in the pulmonary parenchyma.

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CollagenGlycosidesHumansHydroxylysineLungLung DiseasesMaleNitrogen DioxideSpace FlightJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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D V Hatton, C S Leach, A E Nicogossian. Collagen breakdown and nitrogen dioxide inhalation.. https://doi.org/10.1080/00039896.1977.10667250

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