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PubMed · 8341973

[Normal sperm].

Abstract

The evaluation of male infertility rationally begins with a study of the characteristics of the semen, notably sperm count and motility assessment. However, this examination is difficult to interpret due to the important intra- and interindividual variability of these parameters, making it impossible to determine accurately the criteria of "normality". In each given subject the characteristics of semen can be influenced by the conditions of sample collection, the length of abstinence, and any disease that may have occurred in the 3 months preceding the examination. To draw firm conclusions from one single examination would be misleading and a second examination is advised. The criteria of normality laid down by WHO are not very useful to determine the degree of fertility in males: one may speak of oligozoospermia when the sperm count is below 20 million/ml, but several recent prospective studies have shown that fertility significantly falls only below 5 million/ml. A threshold value concerning the percentage of normal forms has been established at 30-40%, whereas teratozoospermia has been defined by the WHO as from 50% onwards. Sperm count can be completed by a fine analysis of sperm motions, and this has been made possible by the development of digital microvideographic analysis techniques. However, defining norms for the main parameters of sperm motility is delicate and can only be done by teams of specialists.

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J F Guérin. 1993-04-15. [Normal sperm].. https://pubmed.ncbi.nlm.nih.gov/8341973/

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MacLeod revisited: sperm count distributions in 374 fertile men from 1971 to 1994.

OBJECTIVES: There has been an enormous amount of interest as to whether sperm counts are declining over time. We sought to compare a contemporary group of fertile men to those from the MacLeod study of 1951 to ascertain whether sperm counts in fertile men have changed over time. METHODS: We obtained sperm count data from 374 fertile men who banked sperm in Minnesota prior to vasectomy from 1971 to 1994 and compared them to sperm count distributions from the 1000 fertile men of MacLeod's study. Semen analyses were performed as per World Health Organization guidelines using identical techniques in both the present and MacLeod studies. RESULTS: The contemporary group had a mean sperm count of 102 +/- 81 x 10(6)/mL (median 85 x 10(6)/mL) compared to 107 +/- 74 x 10(6)/mL (median 90 x 10(6)/mL) for MacLeod's data. There are no significant differences in mean or median sperm counts or sperm count distributions between the groups. CONCLUSIONS: We find remarkable similarities in sperm count distributions in cohorts of fertile men from 1951 and 1971 to 1994. Sperm counts in fertile men have not changed appreciably in the 40 years since MacLeod's report.

Fertility

Fertility.

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Fertility