Search PubMedSearch

PubMed · 8206017

Future directions for functional mapping.

Abstract

The intracarotid amobarbital procedure and direct cortical stimulation are commonly used techniques for functional mapping in candidates for epilepsy surgery. The role of these two procedures has been challenged recently. Emerging technologies recently applied to functional mapping include optical imaging, functional positron emission tomography studies, transcranial magnetic stimulation, magnetoencephalography, and fast magnetic resonance imaging. Studies have used these new technologies and the potential for these procedures to replace the established but more invasive techniques is being considered.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

K Perrine. 1994. Future directions for functional mapping.. https://doi.org/10.1111/j.1528-1157.1994.tb05991.x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Nursing implications of the intracarotid amobarbital procedure.

The intracarotid amobarbital procedure, by inactivation of each hemisphere, provides the opportunity to evaluate language and memory function of the individual considering epilepsy surgery. Careful explanation of this procedure, and its importance to the proposed surgery are vital to the patient's cooperation and performance during this examination. The neuroscience nurse has a significant role in the success of this procedure. Nursing interventions include patient education, monitoring for potential complications, providing comfort measures, and assisting in the management of any life-threatening complications which do develop. A relatively little-known procedure outside of comprehensive epilepsy centers, the IAP offers opportunities for nursing research. These queries include investigation of emotional reactions in relation to gender differences, cultural and educational factors which may effect stimulus selection (eg, bilingual patients) and patient performance.

Amobarbital

Focal cerebral metabolic abnormality in a patient with continuous spike waves during slow-wave sleep.

We report an 11-year-old boy with continuous spike-wave discharges during sleep accompanied by partial motor and atypical absence seizures, psychomotor regression, and severe behavior problems. During wakefulness, epileptiform discharges occurred over the right parietal region, suggesting that the continuous spike-wave discharges during sleep were a manifestation of secondary bilateral synchrony. Bilateral suppression of the spike-and-wave activity was observed after right-sided intracarotid amobarbital injection, further supporting the impression of secondary bilateral synchrony. The right superior temporoparietal increase in metabolic activity during continuous spike-wave discharges and noncontinuous spike-wave discharges was seen on [18F]fluorodeoxyglucose positron emission tomography and supports a right temporoparietal focus in our case. The presence of a focal abnormality suggests that surgical therapy may be effective.

Amobarbital