Tiagabine.

H Mengel

doi:10.1111/j.1528-1157.1994.tb05976.x

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PubMed · 8039477

Tiagabine.

H Mengel

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Abstract

Tiagabine (TGB), a specific gamma-aminobutyric acid (GABA)-uptake inhibitor, is a potential new antiepileptic drug with a novel mechanism of action. In animal models of epilepsy as well as in a placebo-controlled trial in patients with complex partial seizures, TGB showed significant anticonvulsant effects. TGB was well tolerated by most patients.

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Acoustic Stimulation Animals Anticonvulsants Clinical Trials as Topic Drug Evaluation, Preclinical Drug Interactions Epilepsy, Complex Partial Humans Male Mice Nipecotic Acids Rats Rats, Wistar Seizures Tiagabine Journal Article Review

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H Mengel. 1994. Tiagabine.. https://doi.org/10.1111/j.1528-1157.1994.tb05976.x

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